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The map label for this gene is rpiA [H]

Identifier: 162146122

GI number: 162146122

Start: 304984

End: 305688

Strand: Direct

Name: rpiA [H]

Synonym: GDI_0292

Alternate gene names: 162146122

Gene position: 304984-305688 (Clockwise)

Preceding gene: 162146121

Following gene: 162146123

Centisome position: 7.73

GC content: 67.8

Gene sequence:

>705_bases
ATGGGCGTCCAGAATTCGGACCCGATGATTGAACTGAAACGCATGGCGGCGGAAGAAGCCGCCGCCATGGTCCAGGACGG
AATGGCCGTCGGGCTGGGATCGGGCAGCACCTCGGCGATGATGATCGACGCGCTGGGCCGCCGCTGGGCCGAGGGGCTGC
GCTTCGTGGCCATCCCCACCTCGGAACACTCGGCCGAACAGGCGCGCGCGCATGGGATCACGCTGGTGACGTTCGCCACC
CATCCGCAGCTCGACATGGCCATCGACGGCGCGGACGAGGTGGAACGCGGCTCGCTGAACCTGGTCAAGGGTCTGGGGGG
CGCCCTGTTCCGCGAAAAGATCGTCGCCTCGGCAGCGAAGCGCTTCATCATCGTGGTCGATGAAAGCAAGCTGGTCGATC
ATCTGGGCAGCCGGGTCGCGGTCCCGGTCGAAGTCACGTCGTTCGGCTGGGAAAGCACGGCGCGGCAACTGGGCGAACTC
GGCGCCCGGGTGTCGCAGCGCATGGACCGCAATGGCGGCCTGTTCGTGACCGACGGCGGCAACATGATCCTGGACTGCGC
CTTCGGCCCCATCGCCGACCCGCCGCAACTGGCGGCGGACATCCGCGCCATCGTGGGCGTGATCGAAAGCGGACTGTTCA
TCCGTCGCACGTCCGAAGTCATCGTGGCCGGCCGCAGCGGCCTGACCCGCCTGGTGGCGGCATGA

Upstream 100 bases:

>100_bases
GTCTGGCTGCTGGACAAGGCGGCCGCCGCCGTCTGAAAATCGGCCGGCGCGAAAGACAAGAGGACCGCCGGAACACCGGC
AGGTTCCGGGAGGAAGCAAG

Downstream 100 bases:

>100_bases
ACGCCCCCCTGCCGGAAGCGGCGGGCATCCGGCCGCAGATCCTGGTCATCATGGGCGTGTCCGGCTGCGGCAAGACCACG
GTGGCCGAAGGACTGCACAA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MGVQNSDPMIELKRMAAEEAAAMVQDGMAVGLGSGSTSAMMIDALGRRWAEGLRFVAIPTSEHSAEQARAHGITLVTFAT
HPQLDMAIDGADEVERGSLNLVKGLGGALFREKIVASAAKRFIIVVDESKLVDHLGSRVAVPVEVTSFGWESTARQLGEL
GARVSQRMDRNGGLFVTDGGNMILDCAFGPIADPPQLAADIRAIVGVIESGLFIRRTSEVIVAGRSGLTRLVAA

Sequences:

>Translated_234_residues
MGVQNSDPMIELKRMAAEEAAAMVQDGMAVGLGSGSTSAMMIDALGRRWAEGLRFVAIPTSEHSAEQARAHGITLVTFAT
HPQLDMAIDGADEVERGSLNLVKGLGGALFREKIVASAAKRFIIVVDESKLVDHLGSRVAVPVEVTSFGWESTARQLGEL
GARVSQRMDRNGGLFVTDGGNMILDCAFGPIADPPQLAADIRAIVGVIESGLFIRRTSEVIVAGRSGLTRLVAA
>Mature_233_residues
GVQNSDPMIELKRMAAEEAAAMVQDGMAVGLGSGSTSAMMIDALGRRWAEGLRFVAIPTSEHSAEQARAHGITLVTFATH
PQLDMAIDGADEVERGSLNLVKGLGGALFREKIVASAAKRFIIVVDESKLVDHLGSRVAVPVEVTSFGWESTARQLGELG
ARVSQRMDRNGGLFVTDGGNMILDCAFGPIADPPQLAADIRAIVGVIESGLFIRRTSEVIVAGRSGLTRLVAA

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=223, Percent_Identity=37.219730941704, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1789280, Length=216, Percent_Identity=41.2037037037037, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17551758, Length=226, Percent_Identity=33.1858407079646, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=237, Percent_Identity=33.7552742616034, Blast_Score=122, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281364072, Length=218, Percent_Identity=33.4862385321101, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24683; Mature: 24552

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVQNSDPMIELKRMAAEEAAAMVQDGMAVGLGSGSTSAMMIDALGRRWAEGLRFVAIPT
CCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEC
SEHSAEQARAHGITLVTFATHPQLDMAIDGADEVERGSLNLVKGLGGALFREKIVASAAK
CCCCHHHHHHCCEEEEEEECCCCEEEEECCCCHHCCCCHHHHHHCCHHHHHHHHHHHHHC
RFIIVVDESKLVDHLGSRVAVPVEVTSFGWESTARQLGELGARVSQRMDRNGGLFVTDGG
EEEEEECCHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
NMILDCAFGPIADPPQLAADIRAIVGVIESGLFIRRTSEVIVAGRSGLTRLVAA
CEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCHHHHCC
>Mature Secondary Structure 
GVQNSDPMIELKRMAAEEAAAMVQDGMAVGLGSGSTSAMMIDALGRRWAEGLRFVAIPT
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEC
SEHSAEQARAHGITLVTFATHPQLDMAIDGADEVERGSLNLVKGLGGALFREKIVASAAK
CCCCHHHHHHCCEEEEEEECCCCEEEEECCCCHHCCCCHHHHHHCCHHHHHHHHHHHHHC
RFIIVVDESKLVDHLGSRVAVPVEVTSFGWESTARQLGELGARVSQRMDRNGGLFVTDGG
EEEEEECCHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
NMILDCAFGPIADPPQLAADIRAIVGVIESGLFIRRTSEVIVAGRSGLTRLVAA
CEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA