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The map label for this gene is gntK [H]

Identifier: 162146123

GI number: 162146123

Start: 305685

End: 306233

Strand: Direct

Name: gntK [H]

Synonym: GDI_0293

Alternate gene names: 162146123

Gene position: 305685-306233 (Clockwise)

Preceding gene: 162146122

Following gene: 162146124

Centisome position: 7.75

GC content: 66.67

Gene sequence:

>549_bases
ATGAACGCCCCCCTGCCGGAAGCGGCGGGCATCCGGCCGCAGATCCTGGTCATCATGGGCGTGTCCGGCTGCGGCAAGAC
CACGGTGGCCGAAGGACTGCACAACATCCTGGGCTGGCCCTACCAGGAAGGCGACCTGCTGCATCCCCGGGCCAATGTCG
AGAAGATGGCCGCCGGCATTCCGCTGACGGACGAGGATCGCTGGCCCTGGCTGGCACAATGCCGGGCGTGGATCGAGGCC
CGGATCAGGGACGGCGGCGGCGGCATCCTGACCTGCTCGGCGCTGAAACGCGCCTATCGCGACGTGCTGCGCCAGGGGGA
TATGGACCCGGTGGTGTTCGTGTATCTCAAGGTGCCGGAATCGATCCTGAAGGCCCGGCTGGCTCGGCGCACGGGGCATT
ACATGCCGCCCAGCCTGCTGCCCAGCCAGCTCGCGACCCTGGAAGAGCCCACGGCGGACGAGCACGCGCTGGTCATCGAA
AGCGAAAACGCCCCGGCCGAAGTCATCGCCAAGACGATCGGCCAGTTGAAATACCGCATCAAGCGATAA

Upstream 100 bases:

>100_bases
TCCGCGCCATCGTGGGCGTGATCGAAAGCGGACTGTTCATCCGTCGCACGTCCGAAGTCATCGTGGCCGGCCGCAGCGGC
CTGACCCGCCTGGTGGCGGC

Downstream 100 bases:

>100_bases
GGGGCGGCCTGGAATTGGGGCGGTCTCGGCCGGCGGCGGCCCTGTCCTTCGGGCTGGCGGCCGCGTTCGCGCTGCCTCTG
CGCGCGCAGCCCGCGCCGGT

Product: shikimate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MNAPLPEAAGIRPQILVIMGVSGCGKTTVAEGLHNILGWPYQEGDLLHPRANVEKMAAGIPLTDEDRWPWLAQCRAWIEA
RIRDGGGGILTCSALKRAYRDVLRQGDMDPVVFVYLKVPESILKARLARRTGHYMPPSLLPSQLATLEEPTADEHALVIE
SENAPAEVIAKTIGQLKYRIKR

Sequences:

>Translated_182_residues
MNAPLPEAAGIRPQILVIMGVSGCGKTTVAEGLHNILGWPYQEGDLLHPRANVEKMAAGIPLTDEDRWPWLAQCRAWIEA
RIRDGGGGILTCSALKRAYRDVLRQGDMDPVVFVYLKVPESILKARLARRTGHYMPPSLLPSQLATLEEPTADEHALVIE
SENAPAEVIAKTIGQLKYRIKR
>Mature_182_residues
MNAPLPEAAGIRPQILVIMGVSGCGKTTVAEGLHNILGWPYQEGDLLHPRANVEKMAAGIPLTDEDRWPWLAQCRAWIEA
RIRDGGGGILTCSALKRAYRDVLRQGDMDPVVFVYLKVPESILKARLARRTGHYMPPSLLPSQLATLEEPTADEHALVIE
SENAPAEVIAKTIGQLKYRIKR

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=185, Percent_Identity=38.9189189189189, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI87082265, Length=165, Percent_Identity=42.4242424242424, Blast_Score=135, Evalue=1e-33,
Organism=Escherichia coli, GI1790719, Length=143, Percent_Identity=42.6573426573427, Blast_Score=126, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25146487, Length=168, Percent_Identity=44.047619047619, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320454, Length=151, Percent_Identity=36.4238410596026, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 20070; Mature: 20070

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLPEAAGIRPQILVIMGVSGCGKTTVAEGLHNILGWPYQEGDLLHPRANVEKMAAGI
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHCCC
PLTDEDRWPWLAQCRAWIEARIRDGGGGILTCSALKRAYRDVLRQGDMDPVVFVYLKVPE
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCH
SILKARLARRTGHYMPPSLLPSQLATLEEPTADEHALVIESENAPAEVIAKTIGQLKYRI
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KR
CC
>Mature Secondary Structure
MNAPLPEAAGIRPQILVIMGVSGCGKTTVAEGLHNILGWPYQEGDLLHPRANVEKMAAGI
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHCCC
PLTDEDRWPWLAQCRAWIEARIRDGGGGILTCSALKRAYRDVLRQGDMDPVVFVYLKVPE
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCH
SILKARLARRTGHYMPPSLLPSQLATLEEPTADEHALVIESENAPAEVIAKTIGQLKYRI
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]