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The map label for this gene is gudP [H]

Identifier: 162146038

GI number: 162146038

Start: 220555

End: 221811

Strand: Reverse

Name: gudP [H]

Synonym: GDI_0206

Alternate gene names: 162146038

Gene position: 221811-220555 (Counterclockwise)

Preceding gene: 162146039

Following gene: 162146037

Centisome position: 5.62

GC content: 68.1

Gene sequence:

>1257_bases
TTGCTGAATATCGTCCGCCCCGATGTCGTGACACCGCGTCCTTTCCGCTACGTGATCTATGCGCTGGCGGTTGCGATGTG
CGTCATCTGCTATGGGGACCGGGCGGCGCTTTCGGTCGGAATGCCGTCGATCGCCCATGAATTCGGCCTGACGCCGGGCG
AAATCGGCTGGGTGCTGTCCAGCTTTCTCTGGTCCTATTTCATCCTGAACCTGCCCAGCGCGATCCTGCTGGACAGGCTG
GGTGCGCGCACCGTCGGCGCCCTGGCGGTGGCGCTGTGGTCGATGGCCATGATCCTGGGCAGCATGGCCGCCACCATTCC
GGCCTTCATCGCCACACGCGTGCTGCTGGGAATTGGCGAGGCACCGACCTTCTCCCTGGGCAACAAGGTGGTGCGGGCCT
GGGCCCCCCCCACCGAGCGCGGCCTGATGATGACGGCCTTTATCTGCGGCATTCCGATCGGCCTGGCATCCGGCGCCGCG
GCGGGCGCATGGCTGATCGCGCGTTTCGGCTGGCGGCCCGCCTTCGGCATCCTGGGGGCGGGCGGCCTGCTGTGGTCGGT
GGCGTGGTGGCTCGCCCATCCCGCGCAGGTGGAACGGACCCGGACGATGCGGCACGGGATCCTGTCCGTGCCGACATTGT
TCGCCTCGTCCTCGTTCTGGGGGGTCGTCATTGCCCAATGCTGCGCCAATTACGCGAACTTCCTGCTGATGTCGTGGCTG
CCGCTGGTGCTGCGGCAGGTGCTGCACCTGGACATGGTGCAGGCAGGGACCGACACCGCCTATTGCTATTGCGGGGCCGC
GGTCCTGTCGCTTGCCGCGGGCAAGGCCGGCGAACGGCTGATGGCCGGGCGGCCGCTGGTCCGTGGCGCGCGCCGCCATG
TCGTGGCCGTCTTCCTGGTCCTGGCCGCGCTGATGGGATTGCTGCCGTTCTGCACCACCGCCGGCACGATCATTCCCCTG
CTGGCCGTGTCCATGGCCTTCATGGCTGCGGGTACGGGGGCCAACATGGCGCTGCTGGCCGATCTGGTCGTGGAGCACGA
CCTGCTGGGATCGGTCACCGGCCTGACATTGACCTTCAGCAACGGCCTGGGAATCGCCGCCCCCATCATGACGGGCTACC
TGCTGCAGGCCACGGGCAATTTCCACGGCGTCTTCTACATCACCGCCGGCATCATCCTGTGCGGCGCGGCGGCGGCGCTG
ACGATGCCGCGCCGCATGATCCATGCCCGGCCCGTCGCGCGGGGCGCGGCAGGATGA

Upstream 100 bases:

>100_bases
TACTATGTGCGAACGGGCCTGAATTTCTGACCGGCCGCGCTCATCCCCCCGGTCGGATTTTCAGTTAGGCCCCCACACGC
AGTTTACAGGATAGCGCCCC

Downstream 100 bases:

>100_bases
TCCGCCTGAGCATGGCCGGCACCGGCGCCATCCTGCTGGACGCCGCAGCAGGCCCGTTCGACGCCGCGACGCAGCGCCGG
ATCTGGGCGGCGGCGCGCGC

Product: glucarate transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLNIVRPDVVTPRPFRYVIYALAVAMCVICYGDRAALSVGMPSIAHEFGLTPGEIGWVLSSFLWSYFILNLPSAILLDRL
GARTVGALAVALWSMAMILGSMAATIPAFIATRVLLGIGEAPTFSLGNKVVRAWAPPTERGLMMTAFICGIPIGLASGAA
AGAWLIARFGWRPAFGILGAGGLLWSVAWWLAHPAQVERTRTMRHGILSVPTLFASSSFWGVVIAQCCANYANFLLMSWL
PLVLRQVLHLDMVQAGTDTAYCYCGAAVLSLAAGKAGERLMAGRPLVRGARRHVVAVFLVLAALMGLLPFCTTAGTIIPL
LAVSMAFMAAGTGANMALLADLVVEHDLLGSVTGLTLTFSNGLGIAAPIMTGYLLQATGNFHGVFYITAGIILCGAAAAL
TMPRRMIHARPVARGAAG

Sequences:

>Translated_418_residues
MLNIVRPDVVTPRPFRYVIYALAVAMCVICYGDRAALSVGMPSIAHEFGLTPGEIGWVLSSFLWSYFILNLPSAILLDRL
GARTVGALAVALWSMAMILGSMAATIPAFIATRVLLGIGEAPTFSLGNKVVRAWAPPTERGLMMTAFICGIPIGLASGAA
AGAWLIARFGWRPAFGILGAGGLLWSVAWWLAHPAQVERTRTMRHGILSVPTLFASSSFWGVVIAQCCANYANFLLMSWL
PLVLRQVLHLDMVQAGTDTAYCYCGAAVLSLAAGKAGERLMAGRPLVRGARRHVVAVFLVLAALMGLLPFCTTAGTIIPL
LAVSMAFMAAGTGANMALLADLVVEHDLLGSVTGLTLTFSNGLGIAAPIMTGYLLQATGNFHGVFYITAGIILCGAAAAL
TMPRRMIHARPVARGAAG
>Mature_418_residues
MLNIVRPDVVTPRPFRYVIYALAVAMCVICYGDRAALSVGMPSIAHEFGLTPGEIGWVLSSFLWSYFILNLPSAILLDRL
GARTVGALAVALWSMAMILGSMAATIPAFIATRVLLGIGEAPTFSLGNKVVRAWAPPTERGLMMTAFICGIPIGLASGAA
AGAWLIARFGWRPAFGILGAGGLLWSVAWWLAHPAQVERTRTMRHGILSVPTLFASSSFWGVVIAQCCANYANFLLMSWL
PLVLRQVLHLDMVQAGTDTAYCYCGAAVLSLAAGKAGERLMAGRPLVRGARRHVVAVFLVLAALMGLLPFCTTAGTIIPL
LAVSMAFMAAGTGANMALLADLVVEHDLLGSVTGLTLTFSNGLGIAAPIMTGYLLQATGNFHGVFYITAGIILCGAAAAL
TMPRRMIHARPVARGAAG

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=394, Percent_Identity=22.3350253807107, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI9966811, Length=405, Percent_Identity=22.962962962963, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI21322234, Length=438, Percent_Identity=23.0593607305936, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI9945322, Length=405, Percent_Identity=21.9753086419753, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI154350196, Length=235, Percent_Identity=25.531914893617, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI223718438, Length=213, Percent_Identity=26.2910798122066, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1789152, Length=434, Percent_Identity=26.4976958525346, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082320, Length=409, Percent_Identity=26.6503667481663, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI2367379, Length=398, Percent_Identity=28.391959798995, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789515, Length=424, Percent_Identity=23.1132075471698, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI2367193, Length=260, Percent_Identity=22.6923076923077, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=393, Percent_Identity=23.4096692111959, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17554962, Length=374, Percent_Identity=23.5294117647059, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193205400, Length=355, Percent_Identity=24.7887323943662, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565914, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533556, Length=368, Percent_Identity=22.2826086956522, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533554, Length=368, Percent_Identity=22.2826086956522, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=411, Percent_Identity=24.330900243309, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997452, Length=359, Percent_Identity=21.7270194986072, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193208223, Length=380, Percent_Identity=21.8421052631579, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580790, Length=347, Percent_Identity=23.6311239193084, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24648416, Length=424, Percent_Identity=23.5849056603774, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356189, Length=424, Percent_Identity=23.5849056603774, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654215, Length=394, Percent_Identity=24.3654822335025, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922400, Length=394, Percent_Identity=24.3654822335025, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20129235, Length=425, Percent_Identity=24.9411764705882, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641682, Length=418, Percent_Identity=22.488038277512, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24584153, Length=357, Percent_Identity=21.2885154061625, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639764, Length=384, Percent_Identity=23.4375, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24655271, Length=427, Percent_Identity=22.248243559719, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20130135, Length=427, Percent_Identity=22.248243559719, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573299, Length=368, Percent_Identity=23.3695652173913, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24658666, Length=384, Percent_Identity=23.1770833333333, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24658658, Length=392, Percent_Identity=23.9795918367347, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24583789, Length=364, Percent_Identity=23.0769230769231, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920686, Length=420, Percent_Identity=24.047619047619, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573708, Length=236, Percent_Identity=22.0338983050847, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28573707, Length=236, Percent_Identity=22.0338983050847, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44001; Mature: 44001

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIVRPDVVTPRPFRYVIYALAVAMCVICYGDRAALSVGMPSIAHEFGLTPGEIGWVLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHCCCCHHHHHHHH
SFLWSYFILNLPSAILLDRLGARTVGALAVALWSMAMILGSMAATIPAFIATRVLLGIGE
HHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
APTFSLGNKVVRAWAPPTERGLMMTAFICGIPIGLASGAAAGAWLIARFGWRPAFGILGA
CCCHHHCCHHHHHCCCCCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCHHHHHCC
GGLLWSVAWWLAHPAQVERTRTMRHGILSVPTLFASSSFWGVVIAQCCANYANFLLMSWL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
PLVLRQVLHLDMVQAGTDTAYCYCGAAVLSLAAGKAGERLMAGRPLVRGARRHVVAVFLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHH
LAALMGLLPFCTTAGTIIPLLAVSMAFMAAGTGANMALLADLVVEHDLLGSVTGLTLTFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEC
NGLGIAAPIMTGYLLQATGNFHGVFYITAGIILCGAAAALTMPRRMIHARPVARGAAG
CCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLNIVRPDVVTPRPFRYVIYALAVAMCVICYGDRAALSVGMPSIAHEFGLTPGEIGWVLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHCCCCHHHHHHHH
SFLWSYFILNLPSAILLDRLGARTVGALAVALWSMAMILGSMAATIPAFIATRVLLGIGE
HHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
APTFSLGNKVVRAWAPPTERGLMMTAFICGIPIGLASGAAAGAWLIARFGWRPAFGILGA
CCCHHHCCHHHHHCCCCCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCHHHHHCC
GGLLWSVAWWLAHPAQVERTRTMRHGILSVPTLFASSSFWGVVIAQCCANYANFLLMSWL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
PLVLRQVLHLDMVQAGTDTAYCYCGAAVLSLAAGKAGERLMAGRPLVRGARRHVVAVFLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHH
LAALMGLLPFCTTAGTIIPLLAVSMAFMAAGTGANMALLADLVVEHDLLGSVTGLTLTFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEC
NGLGIAAPIMTGYLLQATGNFHGVFYITAGIILCGAAAALTMPRRMIHARPVARGAAG
CCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]