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The map label for this gene is ruvA [H]

Identifier: 162138516

GI number: 162138516

Start: 4855064

End: 4855681

Strand: Reverse

Name: ruvA [H]

Synonym: RPB_4271

Alternate gene names: 162138516

Gene position: 4855681-4855064 (Counterclockwise)

Preceding gene: 86751375

Following gene: 86751373

Centisome position: 91.07

GC content: 68.93

Gene sequence:

>618_bases
ATGATCGGCAAGCTCAAAGGCATCATCGATTCCTACGGCGAGGACTATGTGGTGCTCGACGTCCACGGCGTCGGCTATCA
GGTGCATTGCGCCAGCCGCACGCTGCAGGCGCTGCCGGCGCCGGGCGAGGCGGCGGTGCTGTCGATCGAGACCTATGTGC
GCGAGGATCAGATCAAGCTGTTCGGCTTCCGCACCGATACCGAGCGCGAATGGTTCCGGCTGCTGCAGACGGTGCAGAGC
GTCGGCGCCAAGGTGGCGCTGGCGGTGCTGTCGACGCTGCCGCCGAACGACCTCGCCAACGCCATCGCGCTGCGCGACAA
GGCGGCGGTGGCGCGCACGCCCGGCGTCGGGCCTAAGGTCGCCGAGCGCATCGTCACCGAGTTGAAGGACAAGGTGCCGG
CGCTCGGCAATGTCGATCCGGCGGTGGTGCATCTGTCCGGCGCGCTCGACGATCACCGCGCGCCGCGCCCGGTGACGGAC
GCGATCTCGGCGCTGGTCAATCTCGGCTACGGCCAGCCGCAGGCCGCCGCCGCGATTGCGGCTGCGTCCCGCGCCGCCGG
CGACGATGCCGCGACCGCGCAACTGATCAAGCTCGGCTTGAAGGAGCTGTCTAAGTGA

Upstream 100 bases:

>100_bases
CGGATCGCTACGCGATCCGACCTCCCCCGCAAGCGGGAGAGGTTGCGGAGTGCCGCTTGGCGATTCCGATATCAAGATCG
CGCCTCCCCGGAGCGGTTGC

Downstream 100 bases:

>100_bases
GCCTGACCGAGACCGACCGCGAGTTGATCGCCAGCGCGATCGAGGCGATCAGCCGGCGCTATCGCAACGACTGGCAGGAG
GTCGGCGCCGCGCTGCTGAC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGKLKGIIDSYGEDYVVLDVHGVGYQVHCASRTLQALPAPGEAAVLSIETYVREDQIKLFGFRTDTEREWFRLLQTVQS
VGAKVALAVLSTLPPNDLANAIALRDKAAVARTPGVGPKVAERIVTELKDKVPALGNVDPAVVHLSGALDDHRAPRPVTD
AISALVNLGYGQPQAAAAIAAASRAAGDDAATAQLIKLGLKELSK

Sequences:

>Translated_205_residues
MIGKLKGIIDSYGEDYVVLDVHGVGYQVHCASRTLQALPAPGEAAVLSIETYVREDQIKLFGFRTDTEREWFRLLQTVQS
VGAKVALAVLSTLPPNDLANAIALRDKAAVARTPGVGPKVAERIVTELKDKVPALGNVDPAVVHLSGALDDHRAPRPVTD
AISALVNLGYGQPQAAAAIAAASRAAGDDAATAQLIKLGLKELSK
>Mature_205_residues
MIGKLKGIIDSYGEDYVVLDVHGVGYQVHCASRTLQALPAPGEAAVLSIETYVREDQIKLFGFRTDTEREWFRLLQTVQS
VGAKVALAVLSTLPPNDLANAIALRDKAAVARTPGVGPKVAERIVTELKDKVPALGNVDPAVVHLSGALDDHRAPRPVTD
AISALVNLGYGQPQAAAAIAAASRAAGDDAATAQLIKLGLKELSK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=208, Percent_Identity=36.0576923076923, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21565; Mature: 21565

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLKGIIDSYGEDYVVLDVHGVGYQVHCASRTLQALPAPGEAAVLSIETYVREDQIKL
CCCHHHHHHHHCCCCEEEEEEECCCEEEEEHHHHHHHCCCCCCCEEEEHHHHHHHCCEEE
FGFRTDTEREWFRLLQTVQSVGAKVALAVLSTLPPNDLANAIALRDKAAVARTPGVGPKV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
AERIVTELKDKVPALGNVDPAVVHLSGALDDHRAPRPVTDAISALVNLGYGQPQAAAAIA
HHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
AASRAAGDDAATAQLIKLGLKELSK
HHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLKGIIDSYGEDYVVLDVHGVGYQVHCASRTLQALPAPGEAAVLSIETYVREDQIKL
CCCHHHHHHHHCCCCEEEEEEECCCEEEEEHHHHHHHCCCCCCCEEEEHHHHHHHCCEEE
FGFRTDTEREWFRLLQTVQSVGAKVALAVLSTLPPNDLANAIALRDKAAVARTPGVGPKV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
AERIVTELKDKVPALGNVDPAVVHLSGALDDHRAPRPVTDAISALVNLGYGQPQAAAAIA
HHHHHHHHHHHCCCCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
AASRAAGDDAATAQLIKLGLKELSK
HHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA