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The map label for this gene is apaH [H]

Identifier: 161869599

GI number: 161869599

Start: 630733

End: 631623

Strand: Reverse

Name: apaH [H]

Synonym: NMCC_0615

Alternate gene names: 161869599

Gene position: 631623-630733 (Counterclockwise)

Preceding gene: 161869600

Following gene: 161869598

Centisome position: 29.33

GC content: 57.35

Gene sequence:

>891_bases
ATGATATTTCAAAACCATGCCGTCCGAACCGCAACACTTTCCCACTTCACAACATCTGCAATGGCACATTACGCAATCGG
CGACATACAAGGCTGTTTCGACGAACTGACCGCGCTGCTCGGCAAAATCGGTTTCAACCACGGCACGGACACCCTCTGGC
TGACGGGCGACATCGTCAACCGCGGCCCGAAATCCCTCGAAACGCTGCAATTCTGCATCCGGCACGAAAACAGCGTGCAA
ATCGTCCTCGGCAACCACGACCTGCACCTGCTCGCTGTCGGCTGCGGCGAAGGCGCGCCCAAACGCAGCGACACAATCGA
ACCCATACTCAAACACCCCGACGGAAAAAAAATGCTCGACTGGCTGCGTGCGCAACCGCTGTTGATACGCGAGGGCAGCC
GCGTGATGGTACACGCCGGCATCCTGCCGCAATGGCGCATCGCCAAAGCCGAATCGCTCGCTAGAGAAGCCGAAGCCGAA
CTGCGCGGCAAAAAATACGTCAAATTCTTCTCCAAAATGTACGGCAACAAACCGGCCGCGTGGGACGAAGGTTTGGAAGG
CTATGCCCGCCTGCGCTTCATCGTCAACGCCTTCACGCGGATGCGCGCCCTGACCTTTAAAAACGAACTGGATTTCGACT
ACAAATCCACAGTGAAAAAAATGCCGCCTTACCTGCGCCCGTGGTTCAAAGCCCCCGACCGGCAAAACCTCGACCGCACC
ATCATCTTCGGACACTGGTCCTCGCTGGGCTACACGAATGCCGACAACGTCATCTCGCTGGACACCGGCGCGCTGTGGGG
CGGACAGCTGACCGCCGTCAACCTCGAAACGGAAGAAATTACCCAAGTCCAAGCCGCCGGCGGCATAGACTGGAAAAGCT
TCGCAAAATAA

Upstream 100 bases:

>100_bases
CCGCCCGCGCCGCCGTCGGCGTTGCCTCGCTGCCCAAAGGCGTGCAGGTCGAAGCCGAAGCCGTCCTCGTTTTGAACGCA
TAATTCCACGTTCGGACTGC

Downstream 100 bases:

>100_bases
CGGACCGCCCCACTATGCACAAAATCCTGCCCATCGCCCACGTCCTCTCCCGACTGGGTATGCTGTTTTCCTTTATCCTG
CTGATACCCGCCGCCCTCTC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MIFQNHAVRTATLSHFTTSAMAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVNRGPKSLETLQFCIRHENSVQ
IVLGNHDLHLLAVGCGEGAPKRSDTIEPILKHPDGKKMLDWLRAQPLLIREGSRVMVHAGILPQWRIAKAESLAREAEAE
LRGKKYVKFFSKMYGNKPAAWDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLDRT
IIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK

Sequences:

>Translated_296_residues
MIFQNHAVRTATLSHFTTSAMAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVNRGPKSLETLQFCIRHENSVQ
IVLGNHDLHLLAVGCGEGAPKRSDTIEPILKHPDGKKMLDWLRAQPLLIREGSRVMVHAGILPQWRIAKAESLAREAEAE
LRGKKYVKFFSKMYGNKPAAWDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLDRT
IIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK
>Mature_296_residues
MIFQNHAVRTATLSHFTTSAMAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVNRGPKSLETLQFCIRHENSVQ
IVLGNHDLHLLAVGCGEGAPKRSDTIEPILKHPDGKKMLDWLRAQPLLIREGSRVMVHAGILPQWRIAKAESLAREAEAE
LRGKKYVKFFSKMYGNKPAAWDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLDRT
IIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=262, Percent_Identity=47.7099236641221, Blast_Score=242, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 33259; Mature: 33259

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFQNHAVRTATLSHFTTSAMAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVN
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHC
RGPKSLETLQFCIRHENSVQIVLGNHDLHLLAVGCGEGAPKRSDTIEPILKHPDGKKMLD
CCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHH
WLRAQPLLIREGSRVMVHAGILPQWRIAKAESLAREAEAELRGKKYVKFFSKMYGNKPAA
HHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLDRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCEE
IIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK
EEEEECCCCCCCCCCCEEEECCCCEECCEEEEEECCHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure
MIFQNHAVRTATLSHFTTSAMAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVN
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHC
RGPKSLETLQFCIRHENSVQIVLGNHDLHLLAVGCGEGAPKRSDTIEPILKHPDGKKMLD
CCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHH
WLRAQPLLIREGSRVMVHAGILPQWRIAKAESLAREAEAELRGKKYVKFFSKMYGNKPAA
HHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDEGLEGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLDRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCEE
IIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK
EEEEECCCCCCCCCCCEEEECCCCEECCEEEEEECCHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA