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The map label for this gene is trkH [H]

Identifier: 161869598

GI number: 161869598

Start: 629261

End: 630718

Strand: Reverse

Name: trkH [H]

Synonym: NMCC_0614

Alternate gene names: 161869598

Gene position: 630718-629261 (Counterclockwise)

Preceding gene: 161869599

Following gene: 161869575

Centisome position: 29.29

GC content: 58.98

Gene sequence:

>1458_bases
ATGCACAAAATCCTGCCCATCGCCCACGTCCTCTCCCGACTGGGTATGCTGTTTTCCTTTATCCTGCTGATACCCGCCGC
CCTCTCCTACGCCTTTTCGGACGGCGCGTACACCGCCTTCGCCACCACCGCGACCGTTACCCTTTCCGGCTCGTGCATCG
TCCGGCTCGCCACCCTCCGGTTCAGGCGCGAACTGCGCCCGCGCGACGGCTTCACCCTCGTCCTGATGTTGTGGCTGGCG
TTTGCCGCTATGGCTGCGATGCCGATGTACCTGTATTTCCCGAATATGGGCTTTACCGACGCATTTTTTGAATCGATGTC
GGGACTGACCACCACCGGCGCGACCGTCATCCCCCACGTCGACGGGCTCGCCCCCTCCGTCAACTTTTGGCGGCATATGC
TCAACTGGCTGGGCGGGATGGGCATCATCGTCCTTGCCGTCGCCATCCTGCCTATGCTCGGCGTAGGCGGCACGCAGTTA
TTCAAAGCCGAAATCCCCGGCATTGACAAAGAAAGCAAAATGTCGCCGCGCATTTCCCAAGTGGCGAAAAAACTTTGGTT
CGGCTACACCCTGATCACCATCCTCGCGGCAGCCTGCCTGCATTTTGCCGGGATGGGCTGGTTCGATGCCGTCTGTCACG
CGATGGCGACCCTCTCGCTGGGCGGGTTTTCCACCCACGATGCCAGCATAGCTTATTACAACTCCCCCCTCATCGAAGCA
GTCATCATCGTTTTCACCATTGTCGGCGGCATCAATTTTGCCAGCCATTTCGCCGCCCTCAACAGCCGCAGCCTCAAAAC
CTATTGGAAAGACGAAGAATGCCGGACGATGATGCTGCTGCTCTCCGGCAGCATCCTTGCCGCCGCCCTGTACCTGTGGC
ACACCGGCTATTACGCCGGCTTTATCGAATCCCTGCGCTACACCGCCTTCAACTTCGTCTCCATCGGATTGGCAAACGGG
CTGGCCAACACCGACTTCGCACAATGGCCGCTCCTGATTTCCCTGTGGATGTTTTTCCTCGCCAACATCCTCCCCAACTC
CGGCTCGACCGGCGGCGGCATCAAAACCATACGCGCCCTCGTCCTGTTCAAATTCAGCCTGCGCGAAATGATGGTGCTGC
TGCACCCCAAAGCCGTCCGCACCGTCAAAATCAGCGGCAAGGCCATACCCGACCGCCTCGCGCTGACCGTTATGTCCTTC
ATCTTCATCTACTTTATGACCGTCGTCCTCTTCAGCTTCCTGCTGATGGCGAGCGGTATGGAATTTACCACCGCCTTCAC
CGCCGTCATCGCCTGCATTACCAATTCCGGCCCCGGCCTGGGCGAAGTCGGGCCCGCCGGCAATTACGCCGGTTTGGACG
TGATGCAGAAATGGATCTGCGTTGCCGCCATGCTCTTGGGCAGGCTGGAAATCTTCACCGTCTTCATCCTCTTCACCCCC
GCCTACTGGAAGAAATAA

Upstream 100 bases:

>100_bases
AGCTGACCGCCGTCAACCTCGAAACGGAAGAAATTACCCAAGTCCAAGCCGCCGGCGGCATAGACTGGAAAAGCTTCGCA
AAATAACGGACCGCCCCACT

Downstream 100 bases:

>100_bases
AAAATGCCGTCTGAAAACTTTTCAGACGGCATCTTGTCCTTTAAAGAAGCGGAAGCTCTACAAAAGGAAAGAAATGCTGA
AACCTCTGATAAATTTCAGG

Product: trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MHKILPIAHVLSRLGMLFSFILLIPAALSYAFSDGAYTAFATTATVTLSGSCIVRLATLRFRRELRPRDGFTLVLMLWLA
FAAMAAMPMYLYFPNMGFTDAFFESMSGLTTTGATVIPHVDGLAPSVNFWRHMLNWLGGMGIIVLAVAILPMLGVGGTQL
FKAEIPGIDKESKMSPRISQVAKKLWFGYTLITILAAACLHFAGMGWFDAVCHAMATLSLGGFSTHDASIAYYNSPLIEA
VIIVFTIVGGINFASHFAALNSRSLKTYWKDEECRTMMLLLSGSILAAALYLWHTGYYAGFIESLRYTAFNFVSIGLANG
LANTDFAQWPLLISLWMFFLANILPNSGSTGGGIKTIRALVLFKFSLREMMVLLHPKAVRTVKISGKAIPDRLALTVMSF
IFIYFMTVVLFSFLLMASGMEFTTAFTAVIACITNSGPGLGEVGPAGNYAGLDVMQKWICVAAMLLGRLEIFTVFILFTP
AYWKK

Sequences:

>Translated_485_residues
MHKILPIAHVLSRLGMLFSFILLIPAALSYAFSDGAYTAFATTATVTLSGSCIVRLATLRFRRELRPRDGFTLVLMLWLA
FAAMAAMPMYLYFPNMGFTDAFFESMSGLTTTGATVIPHVDGLAPSVNFWRHMLNWLGGMGIIVLAVAILPMLGVGGTQL
FKAEIPGIDKESKMSPRISQVAKKLWFGYTLITILAAACLHFAGMGWFDAVCHAMATLSLGGFSTHDASIAYYNSPLIEA
VIIVFTIVGGINFASHFAALNSRSLKTYWKDEECRTMMLLLSGSILAAALYLWHTGYYAGFIESLRYTAFNFVSIGLANG
LANTDFAQWPLLISLWMFFLANILPNSGSTGGGIKTIRALVLFKFSLREMMVLLHPKAVRTVKISGKAIPDRLALTVMSF
IFIYFMTVVLFSFLLMASGMEFTTAFTAVIACITNSGPGLGEVGPAGNYAGLDVMQKWICVAAMLLGRLEIFTVFILFTP
AYWKK
>Mature_485_residues
MHKILPIAHVLSRLGMLFSFILLIPAALSYAFSDGAYTAFATTATVTLSGSCIVRLATLRFRRELRPRDGFTLVLMLWLA
FAAMAAMPMYLYFPNMGFTDAFFESMSGLTTTGATVIPHVDGLAPSVNFWRHMLNWLGGMGIIVLAVAILPMLGVGGTQL
FKAEIPGIDKESKMSPRISQVAKKLWFGYTLITILAAACLHFAGMGWFDAVCHAMATLSLGGFSTHDASIAYYNSPLIEA
VIIVFTIVGGINFASHFAALNSRSLKTYWKDEECRTMMLLLSGSILAAALYLWHTGYYAGFIESLRYTAFNFVSIGLANG
LANTDFAQWPLLISLWMFFLANILPNSGSTGGGIKTIRALVLFKFSLREMMVLLHPKAVRTVKISGKAIPDRLALTVMSF
IFIYFMTVVLFSFLLMASGMEFTTAFTAVIACITNSGPGLGEVGPAGNYAGLDVMQKWICVAAMLLGRLEIFTVFILFTP
AYWKK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=480, Percent_Identity=42.0833333333333, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1787626, Length=426, Percent_Identity=40.1408450704225, Blast_Score=323, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53108; Mature: 53108

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKILPIAHVLSRLGMLFSFILLIPAALSYAFSDGAYTAFATTATVTLSGSCIVRLATLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCHHHHHHHHHH
FRRELRPRDGFTLVLMLWLAFAAMAAMPMYLYFPNMGFTDAFFESMSGLTTTGATVIPHV
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHCCCCCCCCCCCCCC
DGLAPSVNFWRHMLNWLGGMGIIVLAVAILPMLGVGGTQLFKAEIPGIDKESKMSPRISQ
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCHHHH
VAKKLWFGYTLITILAAACLHFAGMGWFDAVCHAMATLSLGGFSTHDASIAYYNSPLIEA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHH
VIIVFTIVGGINFASHFAALNSRSLKTYWKDEECRTMMLLLSGSILAAALYLWHTGYYAG
HHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIESLRYTAFNFVSIGLANGLANTDFAQWPLLISLWMFFLANILPNSGSTGGGIKTIRAL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VLFKFSLREMMVLLHPKAVRTVKISGKAIPDRLALTVMSFIFIYFMTVVLFSFLLMASGM
HHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EFTTAFTAVIACITNSGPGLGEVGPAGNYAGLDVMQKWICVAAMLLGRLEIFTVFILFTP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AYWKK
HHHCC
>Mature Secondary Structure
MHKILPIAHVLSRLGMLFSFILLIPAALSYAFSDGAYTAFATTATVTLSGSCIVRLATLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCHHHHHHHHHH
FRRELRPRDGFTLVLMLWLAFAAMAAMPMYLYFPNMGFTDAFFESMSGLTTTGATVIPHV
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHCCCCCCCCCCCCCC
DGLAPSVNFWRHMLNWLGGMGIIVLAVAILPMLGVGGTQLFKAEIPGIDKESKMSPRISQ
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCHHHH
VAKKLWFGYTLITILAAACLHFAGMGWFDAVCHAMATLSLGGFSTHDASIAYYNSPLIEA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHH
VIIVFTIVGGINFASHFAALNSRSLKTYWKDEECRTMMLLLSGSILAAALYLWHTGYYAG
HHHHHHHHHCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIESLRYTAFNFVSIGLANGLANTDFAQWPLLISLWMFFLANILPNSGSTGGGIKTIRAL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VLFKFSLREMMVLLHPKAVRTVKISGKAIPDRLALTVMSFIFIYFMTVVLFSFLLMASGM
HHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EFTTAFTAVIACITNSGPGLGEVGPAGNYAGLDVMQKWICVAAMLLGRLEIFTVFILFTP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AYWKK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]