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The map label for this gene is thrB [H]

Identifier: 161869173

GI number: 161869173

Start: 172622

End: 173539

Strand: Direct

Name: thrB [H]

Synonym: NMCC_0170

Alternate gene names: 161869173

Gene position: 172622-173539 (Clockwise)

Preceding gene: 161869172

Following gene: 161869176

Centisome position: 8.02

GC content: 55.56

Gene sequence:

>918_bases
ATGTCTGTCTATACCAGTGTTTCCGATGATGAAATGCGCGGCTTCCTGAGCGGTTACGATTTGGGGGAATTTGTTTCCCT
GCAGGGCATCGCGCAGGGGATTACCAACAGCAATTATTTTCTGACGACGACTTCGGGACGTTATGTGCTGACCGTGTTTG
AAGTGTTGAAACAGGAAGAGCTGCCGTTTTTTCTGGAGCTTAACCGGCATTTGAGTATGAAGGGCGTGGCGGTTGCCGCG
CCGGTTGCGCGCAAAGACGGCCGGCTTGATTCCGTTTTGGCGGGCAAGCCCGCATGCCTGGTTGCCTGCCTGAAAGGTTC
GGACACCGCGCTGCCGACGGCGGAACAGTGTTTCCATACCGGCGCGATGTTGGCGAAAATGCACCTTGCCGCCGCCGATT
TCCCTTTGGAAATGGAAAACCCGCGTTATGATGCGTGGTGGACAGAGGCGTGCGCCCGACTGCTGCCCGTCCTGCCGCGA
GACGATGCCGCGCTGCTGTGTTCCGAAATCGATGCGCTGAAGGACAATCTCGGCAACCATCTGCCTTCGGGCATCATCCA
CGCCGATTTGTTCAAGGATAATGTGTTGCTTGACGGCGGTCAGGTATCGGGTTTCATCGATTTCTATTATGCCTGCCGGG
GCAATTTTATGTATGACTTGGCGATTGCGGTCAACGATTGGGTAAGGACGGCGGACAATAAGTTGGATGAGGCGTTGAAA
AAGGCGTTTATCGGCGGTTATGAGGGCGTGCGCCCCTTGAGTGCCGAAGAAAAGGCGTATTTCCCGACCGCCCAACGCGC
CGGCTGCATCCGTTTTTGGGTGTCGCGCCTGTTGGATTTTCATTTTCCGCAGGCGGGCGAGATGACGTTTATCAAAGACC
CGAACGCGTTCCGCAACCTGCTGTTGAGTTTGGGTTGA

Upstream 100 bases:

>100_bases
AACTTATGCCCTGTGCGATTCGACCGATGTGAATTATATGTTTGCCTGCCGTCCGGCGTTCTGACGGCGGGTTTGCCCGT
TTTTGAGCAAGTGAGTTGAT

Downstream 100 bases:

>100_bases
GTGCGTCCGGCGTTTGACAGAAATGCCGTCTGAAAGGGTTTCAGACGGCATTTTTATGGCTGATTAAAACGAAAATGAGA
CGATAGCCGGGTATTTTCCA

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTTSGRYVLTVFEVLKQEELPFFLELNRHLSMKGVAVAA
PVARKDGRLDSVLAGKPACLVACLKGSDTALPTAEQCFHTGAMLAKMHLAAADFPLEMENPRYDAWWTEACARLLPVLPR
DDAALLCSEIDALKDNLGNHLPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMYDLAIAVNDWVRTADNKLDEALK
KAFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSRLLDFHFPQAGEMTFIKDPNAFRNLLLSLG

Sequences:

>Translated_305_residues
MSVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTTSGRYVLTVFEVLKQEELPFFLELNRHLSMKGVAVAA
PVARKDGRLDSVLAGKPACLVACLKGSDTALPTAEQCFHTGAMLAKMHLAAADFPLEMENPRYDAWWTEACARLLPVLPR
DDAALLCSEIDALKDNLGNHLPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMYDLAIAVNDWVRTADNKLDEALK
KAFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSRLLDFHFPQAGEMTFIKDPNAFRNLLLSLG
>Mature_304_residues
SVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTTSGRYVLTVFEVLKQEELPFFLELNRHLSMKGVAVAAP
VARKDGRLDSVLAGKPACLVACLKGSDTALPTAEQCFHTGAMLAKMHLAAADFPLEMENPRYDAWWTEACARLLPVLPRD
DAALLCSEIDALKDNLGNHLPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMYDLAIAVNDWVRTADNKLDEALKK
AFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSRLLDFHFPQAGEMTFIKDPNAFRNLLLSLG

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 33687; Mature: 33556

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTTSGRYVLTVFEVLKQEE
CCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCC
LPFFLELNRHLSMKGVAVAAPVARKDGRLDSVLAGKPACLVACLKGSDTALPTAEQCFHT
CCEEEEECCCCCCCCEEEECCCHHCCCCCHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
GAMLAKMHLAAADFPLEMENPRYDAWWTEACARLLPVLPRDDAALLCSEIDALKDNLGNH
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
LPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMYDLAIAVNDWVRTADNKLDEALK
CCCCCEEHHHHCCCEEEECCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHH
KAFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSRLLDFHFPQAGEMTFIKDPNAFRNL
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHH
LLSLG
HHHCC
>Mature Secondary Structure 
SVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTTSGRYVLTVFEVLKQEE
CEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCC
LPFFLELNRHLSMKGVAVAAPVARKDGRLDSVLAGKPACLVACLKGSDTALPTAEQCFHT
CCEEEEECCCCCCCCEEEECCCHHCCCCCHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
GAMLAKMHLAAADFPLEMENPRYDAWWTEACARLLPVLPRDDAALLCSEIDALKDNLGNH
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
LPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMYDLAIAVNDWVRTADNKLDEALK
CCCCCEEHHHHCCCEEEECCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHH
KAFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSRLLDFHFPQAGEMTFIKDPNAFRNL
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHH
LLSLG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]