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The map label for this gene is ubiG

Identifier: 161869172

GI number: 161869172

Start: 171869

End: 172585

Strand: Direct

Name: ubiG

Synonym: NMCC_0169

Alternate gene names: 161869172

Gene position: 171869-172585 (Clockwise)

Preceding gene: 161869152

Following gene: 161869173

Centisome position: 7.98

GC content: 55.23

Gene sequence:

>717_bases
ATGTCCGACAAAAAATATAATGTCGATGAGGGGGAAATCGCCAAATTCAGCCGGATTGCCGACAAATGGTGGGACAAGTC
GGGCGAGTTCAAAACCTTGCACGACATCAATCCGCTGCGGCTGGATTATATCGACGGACACGCGGATTTGCGCGGCAAAC
GGGTTTTGGACGTGGGCTGCGGCGGCGGCATCTTGGCGGAAAGTATGGCGCGGCGCGGCGCGGCGTTTGTAAAGGGCATC
GACATGGCGGAGCAGTCGTTGGAAACCGCCCGCCTGCACGCGGCTTTGAACAATGTCGCCGATATCGAATACGAATGTAT
CCGCGTGGAAGACCTTGCCGAGGCGGAACCGCACTCGTTCGATGTGGTAACGTGCATGGAAATGATGGAACACGTCCCCG
ATCCCGCCGCCATCGTGCGTGCTTGTGCCAATCTGGTCAAACCGGACGGCATGGTGTTTTTTTCCACCATCAATAAAAAC
CCGAAATCGTACCTGCATCTGATTGTGGCGGCGGAATATCTGTTGAAGTTTGTCCCCAAAGGCACGCACGACTGGAAAAA
ATTCATCGCGCCTGCCGAGCTGGCGCGGATGTGCCGTCAGGCAGGCTTGGATGTGGCGGATACGAAGGGTATGACTTACC
ATGTGTTGTCGCAAACTTATGCCCTGTGCGATTCGACCGATGTGAATTATATGTTTGCCTGCCGTCCGGCGTTCTGA

Upstream 100 bases:

>100_bases
GTATTTGCGCCGCGCCGCCCGAAAAGGCTTTCAGACGGCATTGCGTTCCATAGTATAATCTTGGGTTTTGGAGTGGGCGG
TTCGTCAGATGGGAGGGAAA

Downstream 100 bases:

>100_bases
CGGCGGGTTTGCCCGTTTTTGAGCAAGTGAGTTGATATGTCTGTCTATACCAGTGTTTCCGATGATGAAATGCGCGGCTT
CCTGAGCGGTTACGATTTGG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLRLDYIDGHADLRGKRVLDVGCGGGILAESMARRGAAFVKGI
DMAEQSLETARLHAALNNVADIEYECIRVEDLAEAEPHSFDVVTCMEMMEHVPDPAAIVRACANLVKPDGMVFFSTINKN
PKSYLHLIVAAEYLLKFVPKGTHDWKKFIAPAELARMCRQAGLDVADTKGMTYHVLSQTYALCDSTDVNYMFACRPAF

Sequences:

>Translated_238_residues
MSDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLRLDYIDGHADLRGKRVLDVGCGGGILAESMARRGAAFVKGI
DMAEQSLETARLHAALNNVADIEYECIRVEDLAEAEPHSFDVVTCMEMMEHVPDPAAIVRACANLVKPDGMVFFSTINKN
PKSYLHLIVAAEYLLKFVPKGTHDWKKFIAPAELARMCRQAGLDVADTKGMTYHVLSQTYALCDSTDVNYMFACRPAF
>Mature_237_residues
SDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLRLDYIDGHADLRGKRVLDVGCGGGILAESMARRGAAFVKGID
MAEQSLETARLHAALNNVADIEYECIRVEDLAEAEPHSFDVVTCMEMMEHVPDPAAIVRACANLVKPDGMVFFSTINKNP
KSYLHLIVAAEYLLKFVPKGTHDWKKFIAPAELARMCRQAGLDVADTKGMTYHVLSQTYALCDSTDVNYMFACRPAF

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=242, Percent_Identity=36.7768595041322, Blast_Score=174, Evalue=6e-44,
Organism=Escherichia coli, GI1788564, Length=235, Percent_Identity=54.8936170212766, Blast_Score=248, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI115533050, Length=236, Percent_Identity=36.0169491525424, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=283, Percent_Identity=32.5088339222615, Blast_Score=131, Evalue=9e-32,
Organism=Drosophila melanogaster, GI281365311, Length=241, Percent_Identity=30.2904564315353, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24585589, Length=239, Percent_Identity=30.5439330543933, Blast_Score=134, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_NEIM0 (A9M0C4)

Other databases:

- EMBL:   CP000381
- RefSeq:   YP_001598338.1
- ProteinModelPortal:   A9M0C4
- EnsemblBacteria:   EBNEIT00000011041
- GeneID:   5796926
- GenomeReviews:   CP000381_GR
- KEGG:   nmn:NMCC_0169
- GeneTree:   EBGT00050000021250
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- BioCyc:   NMEN374833:NMCC_0169-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26583; Mature: 26452

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLRLDYIDGHADLRGKRVLDVGC
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCEEEEECC
GGGILAESMARRGAAFVKGIDMAEQSLETARLHAALNNVADIEYECIRVEDLAEAEPHSF
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCC
DVVTCMEMMEHVPDPAAIVRACANLVKPDGMVFFSTINKNPKSYLHLIVAAEYLLKFVPK
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
GTHDWKKFIAPAELARMCRQAGLDVADTKGMTYHVLSQTYALCDSTDVNYMFACRPAF
CCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCC
>Mature Secondary Structure 
SDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLRLDYIDGHADLRGKRVLDVGC
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCEEEEECC
GGGILAESMARRGAAFVKGIDMAEQSLETARLHAALNNVADIEYECIRVEDLAEAEPHSF
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCC
DVVTCMEMMEHVPDPAAIVRACANLVKPDGMVFFSTINKNPKSYLHLIVAAEYLLKFVPK
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
GTHDWKKFIAPAELARMCRQAGLDVADTKGMTYHVLSQTYALCDSTDVNYMFACRPAF
CCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA