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The map label for this gene is glmS [H]

Identifier: 161869049

GI number: 161869049

Start: 25395

End: 27233

Strand: Reverse

Name: glmS [H]

Synonym: NMCC_0032

Alternate gene names: 161869049

Gene position: 27233-25395 (Counterclockwise)

Preceding gene: 161869051

Following gene: 161869048

Centisome position: 1.26

GC content: 57.53

Gene sequence:

>1839_bases
ATGTGCGGTATCGTCGGCGCCATCCGCGCCCATCACAACGTCGTCGATTTTCTGACCGACGGTCTCAAACGCCTCGAATA
CCGGGGTTATGACTCATCAGGCATTGCCGTCAACACCGACGGCAAAATCAAACGCGTGCGCCGTGTCGGACGCGTGCAGC
TTATGGAGGACGCGGCACGTGAAAAAGGCATCAGCGGCGGCATCGGCATCGGACATACGCGTTGGGCGACACACGGCGGC
GTTACTGAGCCGAACGCCCACCCGCACATCAGCGGCGGTATGATTGCGGTCGTACACAACGGCATCATCGAAAACTTTGA
AAGCGAACGCAAACGTTTGGAAGGTTTGGGATACCGTTTTGAATCGCAAACGGATACCGAAGTCATCGCACACAGCATCA
ATCACGAATACGCGCAAAACGGCGGCAGGCTGTTTGAAGCGGTACAAGAAGCGGTCAAACGTTTCCACGGCGCATACGCC
ATCGCGGTTATTGCCCAAGACAAGCCTGATGAATTAGTTGTGGCGCGTATGGGCTGCCCGCTTTTGGTCGCTTTGGGCGA
CGATGAAACCTTTATCGCTTCGGACGTATCCGCCGTCATCGCCTTTACGCGCCGCGTGGCGTACCTCGAAGACGGCGACA
TCGCGCTGCTGGCTTCAGACGGCATCAAAAGGCTGACCGATAAAAACGGCCTGCCTGCCGAACGCAAAGTCAAGGTATCC
GAACTCTCGCTCGCCTCTTTGGAACTGGGACCGTACAGCCACTTTATGCAAAAGGAAATCCATGAGCAGCCGCGCGCGAT
TGCAGACACGGCGGAGGTTTTCCTCGACGGCGGCTTCATCCCCGAAAACTTCGGCAAAAACGCCCAAAGCGTGTTTGAAA
GCATCCGCAGCGTCAAAATCCTTGCCTGCGGCACGTCCTATTACGCCGCGCTGACCGCCAAATATTGGTTGGAATCCATC
GCCAAAATCCCGGCCGATGTCGAAATCGCCAGCGAATACCGATACCGCAGCGTGATTGCCGATCCGGACCAACTGGTCAT
TACCATTTCCCAATCCGGCGAAACGCTGGACACGATGGAGGCGTTGAAATACGCAAAATCCTTGGGACACCGCCACAGCC
TCTCCATCTGCAACGTGATGGAATCCGCCCTGCCGCGCGAAAGCAGCCTCGTGCTTTATACCCGTGCCGGTGCGGAAATC
GGCGTCGCCTCAACCAAAGCATTTACCACGCAGCTGGTTGCGCTGTTCGGTTTGGCGGTAACGCTGGCGAAGGTACGCGG
TTTGGTTTCCGGCGAAGATGAAGCACGTTACACCGAAGAACTCCGCCAGCTTCCCGGCAGCGTGCAGCACGCTTTGAACC
TCGAACCGCAAATTGCCGCATGGGCGCAACAGTTTGCCAAGAAAAGCAGCGCGCTGTTTTTAGGGCGCGGCATCCATTAT
CCGATTGCCCTCGAAGGTGCGTTGAAGCTGAAGGAAATCACCTACATCCACGCCGAAGCCTATCCTGCCGGCGAACTGAA
GCACGGGCCGCTTGCCTTAGTGGACGAAAATATGCCCGTCGTCGTCATCGCGCCCAACGACAGCCTATTGGACAAAGTCA
AAGCCAATATGCAGGAAGTCGGCGCGCGCGGCGGCGAACTTTTCGTCTTTGCCGACCTCGACAGCAATTTTAATGCCACC
GAAGGCGTGCACGTTATCCGTGCGCCGCGCCATGTCGGCGAACTGTCCCCCGTCGTGCATACCATCCCCGTGCAGCTCCT
CGCCTACCACACCGCCCTCGCGCGCGGCACGGATGTAGACAAGCCGCGCAACCTGGCGAAATCCGTAACCGTCGAATAA

Upstream 100 bases:

>100_bases
TGTTTTTCGGCGCGGGAGGCGGTTTATAATCCGAAGCGGAAGGTGCGGCACGAGAGCCGTCCGCGCCTGTTTTTTTTCAA
CCGGATACTAAGGAACAGTT

Downstream 100 bases:

>100_bases
ATACCGCCGGTTGGCAAAAATGCCGTCTGAAGCCCGATTTTTCAGGCTTCAGACGGCATTTCCCCGTTTGATTTGCGGTA
TAATCCGCCTTTACCCTTTG

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAAREKGISGGIGIGHTRWATHGG
VTEPNAHPHISGGMIAVVHNGIIENFESERKRLEGLGYRFESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYA
IAVIAQDKPDELVVARMGCPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLASDGIKRLTDKNGLPAERKVKVS
ELSLASLELGPYSHFMQKEIHEQPRAIADTAEVFLDGGFIPENFGKNAQSVFESIRSVKILACGTSYYAALTAKYWLESI
AKIPADVEIASEYRYRSVIADPDQLVITISQSGETLDTMEALKYAKSLGHRHSLSICNVMESALPRESSLVLYTRAGAEI
GVASTKAFTTQLVALFGLAVTLAKVRGLVSGEDEARYTEELRQLPGSVQHALNLEPQIAAWAQQFAKKSSALFLGRGIHY
PIALEGALKLKEITYIHAEAYPAGELKHGPLALVDENMPVVVIAPNDSLLDKVKANMQEVGARGGELFVFADLDSNFNAT
EGVHVIRAPRHVGELSPVVHTIPVQLLAYHTALARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_612_residues
MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAAREKGISGGIGIGHTRWATHGG
VTEPNAHPHISGGMIAVVHNGIIENFESERKRLEGLGYRFESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYA
IAVIAQDKPDELVVARMGCPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLASDGIKRLTDKNGLPAERKVKVS
ELSLASLELGPYSHFMQKEIHEQPRAIADTAEVFLDGGFIPENFGKNAQSVFESIRSVKILACGTSYYAALTAKYWLESI
AKIPADVEIASEYRYRSVIADPDQLVITISQSGETLDTMEALKYAKSLGHRHSLSICNVMESALPRESSLVLYTRAGAEI
GVASTKAFTTQLVALFGLAVTLAKVRGLVSGEDEARYTEELRQLPGSVQHALNLEPQIAAWAQQFAKKSSALFLGRGIHY
PIALEGALKLKEITYIHAEAYPAGELKHGPLALVDENMPVVVIAPNDSLLDKVKANMQEVGARGGELFVFADLDSNFNAT
EGVHVIRAPRHVGELSPVVHTIPVQLLAYHTALARGTDVDKPRNLAKSVTVE
>Mature_612_residues
MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAAREKGISGGIGIGHTRWATHGG
VTEPNAHPHISGGMIAVVHNGIIENFESERKRLEGLGYRFESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYA
IAVIAQDKPDELVVARMGCPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLASDGIKRLTDKNGLPAERKVKVS
ELSLASLELGPYSHFMQKEIHEQPRAIADTAEVFLDGGFIPENFGKNAQSVFESIRSVKILACGTSYYAALTAKYWLESI
AKIPADVEIASEYRYRSVIADPDQLVITISQSGETLDTMEALKYAKSLGHRHSLSICNVMESALPRESSLVLYTRAGAEI
GVASTKAFTTQLVALFGLAVTLAKVRGLVSGEDEARYTEELRQLPGSVQHALNLEPQIAAWAQQFAKKSSALFLGRGIHY
PIALEGALKLKEITYIHAEAYPAGELKHGPLALVDENMPVVVIAPNDSLLDKVKANMQEVGARGGELFVFADLDSNFNAT
EGVHVIRAPRHVGELSPVVHTIPVQLLAYHTALARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=693, Percent_Identity=35.7864357864358, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=35.8187134502924, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI1790167, Length=615, Percent_Identity=52.8455284552846, Blast_Score=619, Evalue=1e-178,
Organism=Escherichia coli, GI87082251, Length=323, Percent_Identity=20.4334365325077, Blast_Score=66, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17539970, Length=716, Percent_Identity=31.8435754189944, Blast_Score=307, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17532897, Length=441, Percent_Identity=38.0952380952381, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17532899, Length=441, Percent_Identity=38.0952380952381, Blast_Score=283, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6322745, Length=441, Percent_Identity=39.0022675736961, Blast_Score=284, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6323731, Length=437, Percent_Identity=29.5194508009153, Blast_Score=190, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=34.6341463414634, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357745, Length=694, Percent_Identity=38.6167146974063, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI28573187, Length=144, Percent_Identity=32.6388888888889, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66512; Mature: 66512

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAAR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
EKGISGGIGIGHTRWATHGGVTEPNAHPHISGGMIAVVHNGIIENFESERKRLEGLGYRF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEE
ESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYAIAVIAQDKPDELVVARMGCP
CCCCHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCC
LLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLASDGIKRLTDKNGLPAERKVKVS
EEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEECCCHHHHHCCCCCCHHHEEEHH
ELSLASLELGPYSHFMQKEIHEQPRAIADTAEVFLDGGFIPENFGKNAQSVFESIRSVKI
HEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHCEEE
LACGTSYYAALTAKYWLESIAKIPADVEIASEYRYRSVIADPDQLVITISQSGETLDTME
EEECCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
ALKYAKSLGHRHSLSICNVMESALPRESSLVLYTRAGAEIGVASTKAFTTQLVALFGLAV
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
TLAKVRGLVSGEDEARYTEELRQLPGSVQHALNLEPQIAAWAQQFAKKSSALFLGRGIHY
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCC
PIALEGALKLKEITYIHAEAYPAGELKHGPLALVDENMPVVVIAPNDSLLDKVKANMQEV
CEEECCCEEEEEEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHH
GARGGELFVFADLDSNFNATEGVHVIRAPRHVGELSPVVHTIPVQLLAYHTALARGTDVD
CCCCCEEEEEEECCCCCCCCCCEEEEECCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC
KPRNLAKSVTVE
CHHHHHHHCCCC
>Mature Secondary Structure
MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAAR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
EKGISGGIGIGHTRWATHGGVTEPNAHPHISGGMIAVVHNGIIENFESERKRLEGLGYRF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEE
ESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYAIAVIAQDKPDELVVARMGCP
CCCCHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCC
LLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLASDGIKRLTDKNGLPAERKVKVS
EEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEECCCHHHHHCCCCCCHHHEEEHH
ELSLASLELGPYSHFMQKEIHEQPRAIADTAEVFLDGGFIPENFGKNAQSVFESIRSVKI
HEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHCEEE
LACGTSYYAALTAKYWLESIAKIPADVEIASEYRYRSVIADPDQLVITISQSGETLDTME
EEECCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
ALKYAKSLGHRHSLSICNVMESALPRESSLVLYTRAGAEIGVASTKAFTTQLVALFGLAV
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
TLAKVRGLVSGEDEARYTEELRQLPGSVQHALNLEPQIAAWAQQFAKKSSALFLGRGIHY
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCC
PIALEGALKLKEITYIHAEAYPAGELKHGPLALVDENMPVVVIAPNDSLLDKVKANMQEV
CEEECCCEEEEEEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHH
GARGGELFVFADLDSNFNATEGVHVIRAPRHVGELSPVVHTIPVQLLAYHTALARGTDVD
CCCCCEEEEEEECCCCCCCCCCEEEEECCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC
KPRNLAKSVTVE
CHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA