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The map label for this gene is clpC [H]

Identifier: 161525458

GI number: 161525458

Start: 2499855

End: 2501027

Strand: Direct

Name: clpC [H]

Synonym: Bmul_2288

Alternate gene names: 161525458

Gene position: 2499855-2501027 (Clockwise)

Preceding gene: 161525457

Following gene: 161525459

Centisome position: 72.49

GC content: 63.85

Gene sequence:

>1173_bases
ATGGCCAGAAAACAATGCCAAGTCTGCGGCCAGCCCGCCACGGTGCGGGTGGAAGCCAATCTCAATGGTCGCCACAGCAC
CATGCTGTTGTGTGACGATCACTATCGCCAATTGGTGCGCCAGCAAAAGCGCACCGTCTCGCCGCTCGAAGCGTTGTTCG
GCTCACGCAGCGGCCTGTTCGAAGACTTCCTCGGCAGCGACTTCTTCCGCATCGGTGACGATTCGCCGTCGGGTGCGGCC
GACACCGACGAGGTGGTCGATGCCTCGTTCGGCGAACCCGCCCCGGCTGCTACGGGTACAACGCGCCGGCGCGGCAGTGG
GCTCGCCAGCCGCATCAGCGAACAGTCCGAGGCTTTGTTGCAGGAGGCCGCCAAACATGCCGCCGAATTTGGCCGCGCCG
AAGTCGATACCGAACACCTGCTGCTGGCGCTATCCGACAGCGACGTGGTCAAGACCATCCTGGGGCAGTTCAAGATCAAG
GTCGATGACCTCAAGCGCCAGATCGAATCCGAAGCCAAGCGCGGCGATAAGCCGTTCGAGGGCGAGATCGGCGTGTCGCC
CCGGGTCAAGGACGCGCTCAGCCGTGCTTTCGTGGCCTCCAACGAACTCGGCCACTCTTATGTCGGGCCGGAGCATTTCC
TGATCGGGCTCGCCGAGGAAGGCGAAGGTTTGGCGGCCAACCTGCTGCGCCGTTACGGCCTCACGCCGCAAGCGCTGCGC
CAGCAGGTAAGCAAGGTGGTCGGCAAAGGGGCCGAGGATGGCCGCGCCGAGACGCCGACCAACACGCCCGAGCTGGATAA
ATACTCGCGCGACCTCACCAAGATGGCGCGCGAGGGCAAACTCGATCCAGTCATCGGCCGTGCGCAGGAGATCGAGACCA
CCATCGAGGTGCTGGCCCGGCGCAAGAAAAACAACCCGGTGTTGATCGGTGAGCCCGGCGTCGGCAAGACCGCCATTGTC
GAAGGACTGGCGCAGCGGATGGTCGCCGGCGAAGTGCCCGAGACGCTGCGCGACAAGCGTCTGGTCGAACTCAACATCAA
CGCCATGGTGGCAGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGCGTGCAGAAGGTGCTCAAGGAAGTGACCGAGCACC
AGGGCGAGCTGATTCTGCGTATTTCGGCGAGCGTGATCAGCGATTTCGGTTGA

Upstream 100 bases:

>100_bases
ATGGCTGACGCTGGTCGGCTCGCTTTTCTCAAAACCACAAAAGGATGAGGCTTCGTGATCGGCGGCGTCTCATCAAATCC
ATCTTTACAGGAGCATCAGC

Downstream 100 bases:

>100_bases
ACGTGATCAGTGGTTCCGATTGATGGTGATCGGTCGTTTCGGTCGAAGGTGATCACTTATCACCGGTTTCCGAAACGAGC
GATCATCTTGCCGAAGCGGG

Product: Clp domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MARKQCQVCGQPATVRVEANLNGRHSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGDDSPSGAA
DTDEVVDASFGEPAPAATGTTRRRGSGLASRISEQSEALLQEAAKHAAEFGRAEVDTEHLLLALSDSDVVKTILGQFKIK
VDDLKRQIESEAKRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMAREGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIV
EGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQGELILRISASVISDFG

Sequences:

>Translated_390_residues
MARKQCQVCGQPATVRVEANLNGRHSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGDDSPSGAA
DTDEVVDASFGEPAPAATGTTRRRGSGLASRISEQSEALLQEAAKHAAEFGRAEVDTEHLLLALSDSDVVKTILGQFKIK
VDDLKRQIESEAKRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMAREGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIV
EGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQGELILRISASVISDFG
>Mature_389_residues
ARKQCQVCGQPATVRVEANLNGRHSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGDDSPSGAAD
TDEVVDASFGEPAPAATGTTRRRGSGLASRISEQSEALLQEAAKHAAEFGRAEVDTEHLLLALSDSDVVKTILGQFKIKV
DDLKRQIESEAKRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALRQ
QVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMAREGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIVE
GLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQGELILRISASVISDFG

Specific function: Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1788943, Length=184, Percent_Identity=50.5434782608696, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1787109, Length=282, Percent_Identity=32.2695035460993, Blast_Score=138, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6323002, Length=282, Percent_Identity=34.7517730496454, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6320464, Length=119, Percent_Identity=59.6638655462185, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 42541; Mature: 42409

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKQCQVCGQPATVRVEANLNGRHSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLF
CCCCHHHHCCCCCEEEEEECCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHHHCCCCCHH
EDFLGSDFFRIGDDSPSGAADTDEVVDASFGEPAPAATGTTRRRGSGLASRISEQSEALL
HHHHCCCCEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHH
QEAAKHAAEFGRAEVDTEHLLLALSDSDVVKTILGQFKIKVDDLKRQIESEAKRGDKPFE
HHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCC
GEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHH
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMAREGKLDPVIGRAQEIETTIEVLAR
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHH
RKKNNPVLIGEPGVGKTAIVEGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFE
HCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEEEECCEEEECCHHCCCHH
ERVQKVLKEVTEHQGELILRISASVISDFG
HHHHHHHHHHHHCCCCEEEEEEHHHHHCCC
>Mature Secondary Structure 
ARKQCQVCGQPATVRVEANLNGRHSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLF
CCCHHHHCCCCCEEEEEECCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHHHCCCCCHH
EDFLGSDFFRIGDDSPSGAADTDEVVDASFGEPAPAATGTTRRRGSGLASRISEQSEALL
HHHHCCCCEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHH
QEAAKHAAEFGRAEVDTEHLLLALSDSDVVKTILGQFKIKVDDLKRQIESEAKRGDKPFE
HHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCC
GEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHH
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMAREGKLDPVIGRAQEIETTIEVLAR
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHH
RKKNNPVLIGEPGVGKTAIVEGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFE
HCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEEEECCEEEECCHHCCCHH
ERVQKVLKEVTEHQGELILRISASVISDFG
HHHHHHHHHHHHCCCCEEEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8016066; 7584024; 9384377; 8195092 [H]