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The map label for this gene is 161524726

Identifier: 161524726

GI number: 161524726

Start: 1704731

End: 1705114

Strand: Reverse

Name: 161524726

Synonym: Bmul_1553

Alternate gene names: NA

Gene position: 1705114-1704731 (Counterclockwise)

Preceding gene: 161524727

Following gene: 161524725

Centisome position: 49.45

GC content: 66.41

Gene sequence:

>384_bases
ATGACACTGATCGATCGCATCGACCATCTCGTGCTGACCTGCGTCGATCCCGAGCGCACGCGGCAGTTCTATGTCGACGT
GCTGCAGATGCGGCTCGAAACGTTCGGCGCGGGCCGCATCGCGTTTCGCTTCGGCAACCAGAAGATCAACCTCCACGTGC
GTGGCGCGGAGTTCGAGCCGAAAGCGCACCTGCCGGTGCCGGGCGCGCTCGATCTGTGTCTGATCGCGGCCGTGCCGCTC
GACGACGTGATCGCACACCTGGCACGCGTCGGCTGGCCGATCGTCGAAGGGCCCGTCGAGCGCACCGGCGCGACGCAGCG
GATCCGGTCCGTCTACGTGCGCGATCCCGATCTGAACCTGATCGAGATCGCCGAGCCGGTCTGA

Upstream 100 bases:

>100_bases
TGCCGAGCCAGTTGCTGAAAGCCGGGCGCCGCTCGGACCTGCATCGCCCGCCGGCCGAAGCGAGCGCAGCGCCGCGCGTT
GTCGTCGATGGAGCACGCAC

Downstream 100 bases:

>100_bases
ACGAACCGATCTCGCGGCGCCAGCCGGCGCGGCAGCGCCGTCTCACATGTGCGGCGCGCCGGCTCGCGCACGGCCGCGCC
GACTGTCAACCTGCCAATCC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MTLIDRIDHLVLTCVDPERTRQFYVDVLQMRLETFGAGRIAFRFGNQKINLHVRGAEFEPKAHLPVPGALDLCLIAAVPL
DDVIAHLARVGWPIVEGPVERTGATQRIRSVYVRDPDLNLIEIAEPV

Sequences:

>Translated_127_residues
MTLIDRIDHLVLTCVDPERTRQFYVDVLQMRLETFGAGRIAFRFGNQKINLHVRGAEFEPKAHLPVPGALDLCLIAAVPL
DDVIAHLARVGWPIVEGPVERTGATQRIRSVYVRDPDLNLIEIAEPV
>Mature_126_residues
TLIDRIDHLVLTCVDPERTRQFYVDVLQMRLETFGAGRIAFRFGNQKINLHVRGAEFEPKAHLPVPGALDLCLIAAVPLD
DVIAHLARVGWPIVEGPVERTGATQRIRSVYVRDPDLNLIEIAEPV

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=122, Percent_Identity=54.0983606557377, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14248; Mature: 14117

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIDRIDHLVLTCVDPERTRQFYVDVLQMRLETFGAGRIAFRFGNQKINLHVRGAEFEP
CCHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCC
KAHLPVPGALDLCLIAAVPLDDVIAHLARVGWPIVEGPVERTGATQRIRSVYVRDPDLNL
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHEEECCCCCE
IEIAEPV
EECCCCC
>Mature Secondary Structure 
TLIDRIDHLVLTCVDPERTRQFYVDVLQMRLETFGAGRIAFRFGNQKINLHVRGAEFEP
CHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCC
KAHLPVPGALDLCLIAAVPLDDVIAHLARVGWPIVEGPVERTGATQRIRSVYVRDPDLNL
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHEEECCCCCE
IEIAEPV
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]