Click here to switch to the map view.

The map label for this gene is ywlC [H]

Identifier: 161523856

GI number: 161523856

Start: 739553

End: 740581

Strand: Direct

Name: ywlC [H]

Synonym: Bmul_0676

Alternate gene names: 161523856

Gene position: 739553-740581 (Clockwise)

Preceding gene: 161523855

Following gene: 161523860

Centisome position: 21.45

GC content: 73.57

Gene sequence:

>1029_bases
ATGTCCACCGATCTCCCGAAGTCCGTGACGCCCGCGCAGATCGACGCGGCGGCCGCGCTGCTCGATGCGGGGCAGCTCGT
CGCGTTTCCGACCGAAACCGTCTACGGGCTCGGCGGCGACGCGGCGAGCCCCGACGCCGTCGCGCGCATCTACGCGGCGA
AGGGGCGGCCCGCGAACCATCCGGTGATCGTGCATCTGCCGCCCGGCGGCGATCCCGCGTACTGGGCGGCCGAGCTGCCG
GCCGATGCGCAGAAGCTGATCGACGCATTCTGGCCCGGCCCGCTGACGCTGATCCTGAAGCGCCATCCGCGCATTCCGGA
CGCGGTGAGCGGCGGTCAGGACTCGGTCGGGCTGCGCTGCCCGTCGCATCCGGTCGCGCAGGCGCTGCTCGCCGCATTCA
GCGCGCGGCGCGGCGGTCACGGCGGCGTGGCTGCGCCGTCCGCGAACCGGTTCGGCCACGTGAGCCCGACGACCGCGCAG
CACGTGCGCGACGAATTCGGCGACACGGTGCACGTGCTCGACGGCGGCGCGTCCGAAGTCGGGATCGAATCGACGATTCT
CGATCTGTCGCGCGGCTTTCCGGCGCTGCTGCGCCCGGGCCACGTGACGCCGCAGCAGATCGCCGACGTGCTCGGCCGTG
CGCCGCGGCTGCCGGACGGCAGCGACGCGACTGCGCCGCGCGCGTCGGGCACGCTGAAGGCGCACTACGCGCCCCGCACG
CCGCTCGCGCTGCTGCCGTTCGATGCGCTGGAGCCGCTGCTCGCGGCGGCGCAGGCCGACGGCGAACGCGTCGCGCTGGT
CGCGCGCGCATCGCGCGCCGGGCGCTGGGCACAGGCCGACGGCGTGCATTTCGTCGCGGCGCCCGAAGATCCGCAAGCCT
ATGCGCGCGACCTGTACGGGATGCTGCGCGCGCTCGATCGCGCACAGGTCGCGCGGATTCTCGTCGAAAAGCTGCCCGAG
ACGGTCGAGTGGATCGCGGTCAACGATCGTCTCGGCCGCGCGGCCGCGGCGTTCGAAGCCAGCGATTGA

Upstream 100 bases:

>100_bases
GCCACGTGAATTTCACGGCCGCGACGCGCGACGAAGCGGTCGCCGCCGCGCACGCGTGCGCGCAGCTGCTGCGCGTGCCG
CTCGACTGAGGCGCCGGCCG

Downstream 100 bases:

>100_bases
GCCGCGCCGGCCGCATGCCTTGCGCGCATGTCGGCCCGGTCGTCGTCGCAATGAAAAACCGCCCGACCGGCGAACCGGTC
GGGCGGTTTTTTCGTTGAAG

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSTDLPKSVTPAQIDAAAALLDAGQLVAFPTETVYGLGGDAASPDAVARIYAAKGRPANHPVIVHLPPGGDPAYWAAELP
ADAQKLIDAFWPGPLTLILKRHPRIPDAVSGGQDSVGLRCPSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQ
HVRDEFGDTVHVLDGGASEVGIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
PLALLPFDALEPLLAAAQADGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYGMLRALDRAQVARILVEKLPE
TVEWIAVNDRLGRAAAAFEASD

Sequences:

>Translated_342_residues
MSTDLPKSVTPAQIDAAAALLDAGQLVAFPTETVYGLGGDAASPDAVARIYAAKGRPANHPVIVHLPPGGDPAYWAAELP
ADAQKLIDAFWPGPLTLILKRHPRIPDAVSGGQDSVGLRCPSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQ
HVRDEFGDTVHVLDGGASEVGIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
PLALLPFDALEPLLAAAQADGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYGMLRALDRAQVARILVEKLPE
TVEWIAVNDRLGRAAAAFEASD
>Mature_341_residues
STDLPKSVTPAQIDAAAALLDAGQLVAFPTETVYGLGGDAASPDAVARIYAAKGRPANHPVIVHLPPGGDPAYWAAELPA
DAQKLIDAFWPGPLTLILKRHPRIPDAVSGGQDSVGLRCPSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQH
VRDEFGDTVHVLDGGASEVGIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRTP
LALLPFDALEPLLAAAQADGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYGMLRALDRAQVARILVEKLPET
VEWIAVNDRLGRAAAAFEASD

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI2367210, Length=182, Percent_Identity=29.6703296703297, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=179, Percent_Identity=31.8435754189944, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=376, Percent_Identity=30.3191489361702, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI78707274, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35685; Mature: 35553

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDLPKSVTPAQIDAAAALLDAGQLVAFPTETVYGLGGDAASPDAVARIYAAKGRPANH
CCCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCHHHHHHHHHHCCCCCCC
PVIVHLPPGGDPAYWAAELPADAQKLIDAFWPGPLTLILKRHPRIPDAVSGGQDSVGLRC
CEEEEECCCCCCCCEEECCCHHHHHHHHHHCCCHHEEHHHCCCCCCCCCCCCCCCCCCCC
PSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDTVHVLDGGASEV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCC
GIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
CHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCC
PLALLPFDALEPLLAAAQADGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYG
CEEECCHHHHHHHHHHHHCCCCEEEEEEECHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
MLRALDRAQVARILVEKLPETVEWIAVNDRLGRAAAAFEASD
HHHHHHHHHHHHHHHHHCCHHEEEEEECCHHCHHHHHCCCCC
>Mature Secondary Structure 
STDLPKSVTPAQIDAAAALLDAGQLVAFPTETVYGLGGDAASPDAVARIYAAKGRPANH
CCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCHHHHHHHHHHCCCCCCC
PVIVHLPPGGDPAYWAAELPADAQKLIDAFWPGPLTLILKRHPRIPDAVSGGQDSVGLRC
CEEEEECCCCCCCCEEECCCHHHHHHHHHHCCCHHEEHHHCCCCCCCCCCCCCCCCCCCC
PSHPVAQALLAAFSARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDTVHVLDGGASEV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCC
GIESTILDLSRGFPALLRPGHVTPQQIADVLGRAPRLPDGSDATAPRASGTLKAHYAPRT
CHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCC
PLALLPFDALEPLLAAAQADGERVALVARASRAGRWAQADGVHFVAAPEDPQAYARDLYG
CEEECCHHHHHHHHHHHHCCCCEEEEEEECHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
MLRALDRAQVARILVEKLPETVEWIAVNDRLGRAAAAFEASD
HHHHHHHHHHHHHHHHHCCHHEEEEEECCHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]