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The map label for this gene is purE [H]

Identifier: 161523854

GI number: 161523854

Start: 737729

End: 738259

Strand: Direct

Name: purE [H]

Synonym: Bmul_0674

Alternate gene names: 161523854

Gene position: 737729-738259 (Clockwise)

Preceding gene: 161523853

Following gene: 161523855

Centisome position: 21.39

GC content: 68.55

Gene sequence:

>531_bases
ATGCACGAAATGAACGAAGTCCAGACCGCCCACACGCACAGCGCGCCGCTCGTCGGCGTGCTGATGGGTTCGAGTTCCGA
CTGGGACGTGATGAAGCACGCGGTAGCGATCCTGCAGGAATTCGGCGTGCCCTACGAAGCGAAGGTCGTGTCCGCGCACC
GGATGCCCGACGAGATGTTCGACTATGCGGAGAAGGCGCGCGAGCGCGGGCTGCGCGCGATCATCGCGGGCGCCGGCGGT
GCCGCGCACCTGCCCGGCATGCTCGCGGCGAAGACGACGGTGCCCGTGCTCGGCGTGCCGGTCGCGAGCAAGTATCTGAA
GGGCGTCGATTCGCTGCACTCGATCGTGCAGATGCCGAAGGGCGTGCCGGTCGCGACGTTCGCGATCGGCGAGGCTGGCG
CCGCGAATGCCGCGCTGTTCGCGGTGTCGATCCTGTCCGGCACGTCGGTCGACTACGCGAACCGGCTCGCGGCGTTCCGC
GTGCGCCAGAACGAAGCCGCGCACGCGATGGTGCTGCCGCCGCTCGAATGA

Upstream 100 bases:

>100_bases
CCGGCGCCGGCGCTGCCGGCCGACGTCGTCGAGAAGACGGCCGCGAAGTACCAGGAAGCGCTCGAGCGCATCACGGGCCA
GCCGCTCGCCTGACGGGGGA

Downstream 100 bases:

>100_bases
CGGGACGGCGCGCGCCGCACGGCACGCGCCGGATTTTCCCAGTGCGGCGGGTGCTTCCCGTTTCCCGTCGCGATCGATCA
CTGACATGACCGCAACTCCT

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MHEMNEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFGVPYEAKVVSAHRMPDEMFDYAEKARERGLRAIIAGAGG
AAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFR
VRQNEAAHAMVLPPLE

Sequences:

>Translated_176_residues
MHEMNEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFGVPYEAKVVSAHRMPDEMFDYAEKARERGLRAIIAGAGG
AAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFR
VRQNEAAHAMVLPPLE
>Mature_176_residues
MHEMNEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFGVPYEAKVVSAHRMPDEMFDYAEKARERGLRAIIAGAGG
AAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFR
VRQNEAAHAMVLPPLE

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=110, Percent_Identity=62.7272727272727, Blast_Score=145, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324702, Length=150, Percent_Identity=57.3333333333333, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 18525; Mature: 18525

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMNEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFGVPYEAKVVSAHRMPDEMF
CCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
DYAEKARERGLRAIIAGAGGAAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPK
HHHHHHHHCCCEEEEECCCCHHHCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCC
GVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFRVRQNEAAHAMVLPPLE
CCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
>Mature Secondary Structure
MHEMNEVQTAHTHSAPLVGVLMGSSSDWDVMKHAVAILQEFGVPYEAKVVSAHRMPDEMF
CCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
DYAEKARERGLRAIIAGAGGAAHLPGMLAAKTTVPVLGVPVASKYLKGVDSLHSIVQMPK
HHHHHHHHCCCEEEEECCCCHHHCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCC
GVPVATFAIGEAGAANAALFAVSILSGTSVDYANRLAAFRVRQNEAAHAMVLPPLE
CCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]