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The map label for this gene is purC [H]

Identifier: 161523853

GI number: 161523853

Start: 736831

End: 737721

Strand: Direct

Name: purC [H]

Synonym: Bmul_0673

Alternate gene names: 161523853

Gene position: 736831-737721 (Clockwise)

Preceding gene: 161523852

Following gene: 161523854

Centisome position: 21.37

GC content: 66.33

Gene sequence:

>891_bases
ATGTCTACCCTTTACGAATCCACGCTCCGCTCGCTGCCGCTCCTCGGTCGCGGCAAGGTCCGCGACAACTATGCGGTCGG
CAACGACAAGCTCCTGATCGTCACGACCGATCGTCTGTCGGCATTCGACGTGATCATGGGCGAGCCGATTCCGAACAAGG
GCCGCGTGCTGAACCAGATGGCGAACTTCTGGTTCGACAAGCTCGCGCACATCGTGCCGAACCACCTGACCGGCGACGCA
CCCGAAGCCGTCGTCGCGGCGGACGAGGTCGAGCAGGTGAAGGGCCGCGCCGTGGTCGTCAAGCGTCTCGAGCCGATCCT
GATCGAAGCGGTCGTGCGCGGTTATCTGGCCGGCAGCGGCTGGAAGGAATACCAGGCGACGGGCGCCGTATGCGGCGTGC
AGCTGCCGGCCGGCCTGCAGAACGCGCAGAAGCTGCCCGAGCCGATCTTCACGCCCGCGGCCAAGGCCGAGATGGGCGAA
CACGACGAGAACATCACGTTCGAGGAAACCGAGCGCCGCATCGGCACCGAGCTCGCCGCGACGATCCGCGACATCTCGAT
CAAGCTGTACAAGGAAGCGGCCGACTACGCGGCCACGCGCGGCATCATCATCGCCGACACGAAGTTCGAATTCGGCCTCG
ACAATCACGGCAAGCTGTATCTGATGGACGAAGTGCTGACGGCCGACTCGTCGCGCTTCTGGCCGGCCGACCAGTACCAG
GTCGGCACGAACCCGCCGTCGTTCGACAAGCAGTTCGTGCGCGACTGGCTCGAGGCGCAGCCGTGGGGCAAGACCGCGCC
GGCGCCGGCGCTGCCGGCCGACGTCGTCGAGAAGACGGCCGCGAAGTACCAGGAAGCGCTCGAGCGCATCACGGGCCAGC
CGCTCGCCTGA

Upstream 100 bases:

>100_bases
CCGCCCGCCGGTTCGCCGACGTATCGCAAGGCCGCCGTTCCCGCCAGCCGCGGGGAACGGCGTTTCCCTTTTTGTTTGGC
TCCTTATCTGCGAAAAGACG

Downstream 100 bases:

>100_bases
CGGGGGAATGCACGAAATGAACGAAGTCCAGACCGCCCACACGCACAGCGCGCCGCTCGTCGGCGTGCTGATGGGTTCGA
GTTCCGACTGGGACGTGATG

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSTLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVIMGEPIPNKGRVLNQMANFWFDKLAHIVPNHLTGDA
PEAVVAADEVEQVKGRAVVVKRLEPILIEAVVRGYLAGSGWKEYQATGAVCGVQLPAGLQNAQKLPEPIFTPAAKAEMGE
HDENITFEETERRIGTELAATIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGKLYLMDEVLTADSSRFWPADQYQ
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQPLA

Sequences:

>Translated_296_residues
MSTLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVIMGEPIPNKGRVLNQMANFWFDKLAHIVPNHLTGDA
PEAVVAADEVEQVKGRAVVVKRLEPILIEAVVRGYLAGSGWKEYQATGAVCGVQLPAGLQNAQKLPEPIFTPAAKAEMGE
HDENITFEETERRIGTELAATIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGKLYLMDEVLTADSSRFWPADQYQ
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQPLA
>Mature_295_residues
STLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVIMGEPIPNKGRVLNQMANFWFDKLAHIVPNHLTGDAP
EAVVAADEVEQVKGRAVVVKRLEPILIEAVVRGYLAGSGWKEYQATGAVCGVQLPAGLQNAQKLPEPIFTPAAKAEMGEH
DENITFEETERRIGTELAATIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGKLYLMDEVLTADSSRFWPADQYQV
GTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQPLA

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=291, Percent_Identity=46.7353951890034, Blast_Score=266, Evalue=3e-72,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 32594; Mature: 32463

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVIMGEPIPNKGRVLNQM
CCHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
ANFWFDKLAHIVPNHLTGDAPEAVVAADEVEQVKGRAVVVKRLEPILIEAVVRGYLAGSG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
WKEYQATGAVCGVQLPAGLQNAQKLPEPIFTPAAKAEMGEHDENITFEETERRIGTELAA
CHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
TIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGKLYLMDEVLTADSSRFWPADQYQ
HHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCEEEEHHHHHCCCCCCCCCCCEE
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQPLA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVIMGEPIPNKGRVLNQM
CHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
ANFWFDKLAHIVPNHLTGDAPEAVVAADEVEQVKGRAVVVKRLEPILIEAVVRGYLAGSG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
WKEYQATGAVCGVQLPAGLQNAQKLPEPIFTPAAKAEMGEHDENITFEETERRIGTELAA
CHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
TIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGKLYLMDEVLTADSSRFWPADQYQ
HHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCEEEEHHHHHCCCCCCCCCCCEE
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQPLA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA