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The map label for this gene is pdxA [H]

Identifier: 161523770

GI number: 161523770

Start: 645791

End: 646780

Strand: Direct

Name: pdxA [H]

Synonym: Bmul_0590

Alternate gene names: 161523770

Gene position: 645791-646780 (Clockwise)

Preceding gene: 161523769

Following gene: 161523771

Centisome position: 18.73

GC content: 72.22

Gene sequence:

>990_bases
ATGAGCGCGCGCGCCTTGCAGATCGCGATCACGACCGGCGAGCCGGCTGGCGTCGGTCCGGAGCTGACCGTGCAGGCGCT
GCGCGACGCCGGCGAGCGCTGGCCCGATGCGCAGTTCACGGTGCTCGGCGACGCCGCGCTGCTCGAAGCGCGCGCGGCGG
CCGTCGGTGCCGACTGGGCCGCGCTGGTCGGCGGTTCGCGCGTGTCGGTCGCGCATCATGCGCTCGCGGCGCCCGCGCAT
GCGGGCCGGCTCGACGCGGCGAACGGCCGCTACGTGCTCGCGCTGCTCGATGCGGCGATCGACGGCGCCGTGGCCGGCCG
CTACGACGCGATCGTCACCGCGCCGCTGCAGAAGAGCACGATCAACGATGCCGGCGTGCCGTTCACCGGCCATACCGAAT
ATCTGGCCGAGCGCACGCATACGGCGCGCGTCGTGATGATGCTCGCGGGCACCGGCGCAACGCCCCTGCGCGTCGCGCTC
GCCACGACGCATCTGCCGCTGAAGGACGTGTCGGCCGCGCTGACGATCGACGGGCTCGTCGAGACGCTCGCGATCATCGA
CCGCGACCTGCGGCGCGACTTCGGGCTCGCCAGGCCGCGGATCCTCGTGACGGGCCTCAATCCGCATGCGGGCGAAAACG
GTTATCTCGGCCGCGAGGAAATCGACGTGATCGCACCGGCGCTCGCGCGTGCCCAGGCGCAGCAGATCGACGCACGCGGC
CCGTATCCGGCCGACACGCTGTTCCAGCCGCGCTATCTCGCCGACGCCGACTGCGTGCTCGCGATGTTCCACGATCAGGG
GCTGCCGGTACTGAAGTACGCGACGTTCGGTGAAGGCATCAACGTGACGCTCGGGCTGCCGATCATCCGCACGTCGGTCG
ACCACGGCACCGCGCTCGACCTCGCCGGCACCGGCCGCGCCGATCCCGGCAGCATGATCGCGGCGCTCGATACGGCCGTG
ACGATGGCGCGGCATCGGCGCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCAAGGCCGAGCAGGCGTATGCGGACTGGCTGCGCGAACTGCGCGATTCGTCCTACGTGCAGTACAAGATCGGCGGCCT
GCCGTCGAACTGAGCCGACG

Downstream 100 bases:

>100_bases
CGCGGCATGCCTGACCCGGCCCGGCCTGACGCGGCCAGCGTCGCTCGCGGCCGCCGCTTCCTTACTCATCGCATTTTTGG
TTTTTTCTTCAGCCGATGTC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSARALQIAITTGEPAGVGPELTVQALRDAGERWPDAQFTVLGDAALLEARAAAVGADWAALVGGSRVSVAHHALAAPAH
AGRLDAANGRYVLALLDAAIDGAVAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTARVVMMLAGTGATPLRVAL
ATTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLARPRILVTGLNPHAGENGYLGREEIDVIAPALARAQAQQIDARG
PYPADTLFQPRYLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAV
TMARHRRAA

Sequences:

>Translated_329_residues
MSARALQIAITTGEPAGVGPELTVQALRDAGERWPDAQFTVLGDAALLEARAAAVGADWAALVGGSRVSVAHHALAAPAH
AGRLDAANGRYVLALLDAAIDGAVAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTARVVMMLAGTGATPLRVAL
ATTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLARPRILVTGLNPHAGENGYLGREEIDVIAPALARAQAQQIDARG
PYPADTLFQPRYLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAV
TMARHRRAA
>Mature_328_residues
SARALQIAITTGEPAGVGPELTVQALRDAGERWPDAQFTVLGDAALLEARAAAVGADWAALVGGSRVSVAHHALAAPAHA
GRLDAANGRYVLALLDAAIDGAVAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTARVVMMLAGTGATPLRVALA
TTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLARPRILVTGLNPHAGENGYLGREEIDVIAPALARAQAQQIDARGP
YPADTLFQPRYLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAVT
MARHRRAA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=329, Percent_Identity=53.1914893617021, Blast_Score=327, Evalue=7e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34299; Mature: 34167

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARALQIAITTGEPAGVGPELTVQALRDAGERWPDAQFTVLGDAALLEARAAAVGADWA
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCHH
ALVGGSRVSVAHHALAAPAHAGRLDAANGRYVLALLDAAIDGAVAGRYDAIVTAPLQKST
HHHCCCEEHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCEEEECCCCCCC
INDAGVPFTGHTEYLAERTHTARVVMMLAGTGATPLRVALATTHLPLKDVSAALTIDGLV
CCCCCCCCCCCHHHHHHHHHHEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHEEHHHHH
ETLAIIDRDLRRDFGLARPRILVTGLNPHAGENGYLGREEIDVIAPALARAQAQQIDARG
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PYPADTLFQPRYLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
CCCCCCCCCCCCCCCCHHEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCCEEE
LAGTGRADPGSMIAALDTAVTMARHRRAA
ECCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SARALQIAITTGEPAGVGPELTVQALRDAGERWPDAQFTVLGDAALLEARAAAVGADWA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCHH
ALVGGSRVSVAHHALAAPAHAGRLDAANGRYVLALLDAAIDGAVAGRYDAIVTAPLQKST
HHHCCCEEHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCEEEECCCCCCC
INDAGVPFTGHTEYLAERTHTARVVMMLAGTGATPLRVALATTHLPLKDVSAALTIDGLV
CCCCCCCCCCCHHHHHHHHHHEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHEEHHHHH
ETLAIIDRDLRRDFGLARPRILVTGLNPHAGENGYLGREEIDVIAPALARAQAQQIDARG
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PYPADTLFQPRYLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
CCCCCCCCCCCCCCCCHHEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCCEEE
LAGTGRADPGSMIAALDTAVTMARHRRAA
ECCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA