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The map label for this gene is surA [H]

Identifier: 161523769

GI number: 161523769

Start: 644428

End: 645783

Strand: Direct

Name: surA [H]

Synonym: Bmul_0589

Alternate gene names: 161523769

Gene position: 644428-645783 (Clockwise)

Preceding gene: 161523768

Following gene: 161523770

Centisome position: 18.69

GC content: 67.7

Gene sequence:

>1356_bases
ATGAAGAAAACCCTTCGTTTCGCGGCAGTCGTGTCCAGCCTCGCCGCGTCCGCCGCGCTGCTCGCCGCCGCGCCGGCCGC
GGCGCAGGCGCTCGGTTCGCAAGGCGCGCAGCTCGCCGACGAAGTCGTCGCGGTCGTCAACAACGACGTGATCACGGGCC
GCGAACTCGACCAGCGCGTCGGCCTGATCTCGCGTCGGCTGCAGCAGCAGAACGCGCCCGTGCCGCCGATCGACCAGTTG
CGCGCGCAGGTGCTGAACCAGATGGTGCTCGAGCGCATCCAGGTGCAGAAGGCGAAGGACGACGGGATCCGCGTCGACGA
CGCGACGGTGCAGGCCACGCTGCAGCGCCTCGCGCAGGCGAACGGGATGACGCTCGACCAGTATCGCTCGCGTCTCGAAG
CGCAAGGCGTGCCGTGGAGCATCTTCACGGCCGATGCGCGTACCGAACTGATGCTGTCGAAGCTGCGCGAGCGCGAGGTC
GACAGCAAGATCACCGTGTCGGACGCCGAAGTCGCAAGCTACATCGCGAGCCAGCGCGGGCCGAACGCCTCGCAGCAACA
GGACCTGCGCTTCCAGCACATCTTCATCAAGGCGCCGACCAACGCGCCGCAGACGCAGATCGAAGCCGCGCAGAAGAAGG
CCGAGGCGCTGCTGCAGCAAGCGACATCGGGTGCCGATTTCGAGAAGCTCGCGAAGAACAATTCGGAAGCCGACGATGCG
AAGAAGGGCGGCGATCTCGGCTTCAAGTCGCCGAGCGCGCTGCCGGCCGATGTCGTCGACGCCGCGGCGAAGCTGCGTCC
GGGGCAGGTCAACCCGACGCTGATCCGCGTGCCGGACGGCTTCGAGATCATCCGCCTCGTCGATCGCCGGCAGAGCCAGG
GCGCGACGGCCGCGGCGCCGAAGATCGTGCAGACGCACGTGCGCCACATCCTGCTGCGCGTCGGCGAAGGCAAGTCCGAA
GGGCAGGCGCGCCAGCAACTGATCGACATCCGCCGGCAGATCGAGGCCGGCGGCGACTTCGAGAAGTTCGCGCGTACCTA
TTCGCAGGACGGTTCCGCGTCGCAGGGCGGCGATCTCGGCTGGATCAGCCCCGGCGAGACGGTGCCCGAATTCGAGCGCG
CGATGAACGCGCTGCAGGACGGCCAGATCAGCCAGCCCATTCGTACCGAGTACGGCTATCACCTGATCCAGGTCGTCGGC
CGCCGCGAAGCGGAAGGCTCGGTGCAGCAGCAGATGGATATCGCGCGTCAGGCGATCGGCCAGCGCAAGGCCGAGCAGGC
GTATGCGGACTGGCTGCGCGAACTGCGCGATTCGTCCTACGTGCAGTACAAGATCGGCGGCCTGCCGTCGAACTGA

Upstream 100 bases:

>100_bases
GCCGCTGCCGTCGGCACCGCCGCCGATGTCCCGCTTCAGCAACTACGAGTAACGCGGCCTGTCTGACCGGTCAGCCGATT
TCAATGGAGTATCAGTGGCA

Downstream 100 bases:

>100_bases
GCCGACGATGAGCGCGCGCGCCTTGCAGATCGCGATCACGACCGGCGAGCCGGCTGGCGTCGGTCCGGAGCTGACCGTGC
AGGCGCTGCGCGACGCCGGC

Product: SurA domain-containing protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKKTLRFAAVVSSLAASAALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRVGLISRRLQQQNAPVPPIDQL
RAQVLNQMVLERIQVQKAKDDGIRVDDATVQATLQRLAQANGMTLDQYRSRLEAQGVPWSIFTADARTELMLSKLREREV
DSKITVSDAEVASYIASQRGPNASQQQDLRFQHIFIKAPTNAPQTQIEAAQKKAEALLQQATSGADFEKLAKNNSEADDA
KKGGDLGFKSPSALPADVVDAAAKLRPGQVNPTLIRVPDGFEIIRLVDRRQSQGATAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNALQDGQISQPIRTEYGYHLIQVVG
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGLPSN

Sequences:

>Translated_451_residues
MKKTLRFAAVVSSLAASAALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRVGLISRRLQQQNAPVPPIDQL
RAQVLNQMVLERIQVQKAKDDGIRVDDATVQATLQRLAQANGMTLDQYRSRLEAQGVPWSIFTADARTELMLSKLREREV
DSKITVSDAEVASYIASQRGPNASQQQDLRFQHIFIKAPTNAPQTQIEAAQKKAEALLQQATSGADFEKLAKNNSEADDA
KKGGDLGFKSPSALPADVVDAAAKLRPGQVNPTLIRVPDGFEIIRLVDRRQSQGATAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNALQDGQISQPIRTEYGYHLIQVVG
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGLPSN
>Mature_451_residues
MKKTLRFAAVVSSLAASAALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRVGLISRRLQQQNAPVPPIDQL
RAQVLNQMVLERIQVQKAKDDGIRVDDATVQATLQRLAQANGMTLDQYRSRLEAQGVPWSIFTADARTELMLSKLREREV
DSKITVSDAEVASYIASQRGPNASQQQDLRFQHIFIKAPTNAPQTQIEAAQKKAEALLQQATSGADFEKLAKNNSEADDA
KKGGDLGFKSPSALPADVVDAAAKLRPGQVNPTLIRVPDGFEIIRLVDRRQSQGATAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNALQDGQISQPIRTEYGYHLIQVVG
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGLPSN

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=390, Percent_Identity=33.5897435897436, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49145; Mature: 49145

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLRFAAVVSSLAASAALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GLISRRLQQQNAPVPPIDQLRAQVLNQMVLERIQVQKAKDDGIRVDDATVQATLQRLAQA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NGMTLDQYRSRLEAQGVPWSIFTADARTELMLSKLREREVDSKITVSDAEVASYIASQRG
CCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHCCC
PNASQQQDLRFQHIFIKAPTNAPQTQIEAAQKKAEALLQQATSGADFEKLAKNNSEADDA
CCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHH
KKGGDLGFKSPSALPADVVDAAAKLRPGQVNPTLIRVPDGFEIIRLVDRRQSQGATAAAP
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHH
KIVQTHVRHILLRVGEGKSEGQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
WISPGETVPEFERAMNALQDGQISQPIRTEYGYHLIQVVGRREAEGSVQQQMDIARQAIG
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QRKAEQAYADWLRELRDSSYVQYKIGGLPSN
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure
MKKTLRFAAVVSSLAASAALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GLISRRLQQQNAPVPPIDQLRAQVLNQMVLERIQVQKAKDDGIRVDDATVQATLQRLAQA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NGMTLDQYRSRLEAQGVPWSIFTADARTELMLSKLREREVDSKITVSDAEVASYIASQRG
CCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHCCC
PNASQQQDLRFQHIFIKAPTNAPQTQIEAAQKKAEALLQQATSGADFEKLAKNNSEADDA
CCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHH
KKGGDLGFKSPSALPADVVDAAAKLRPGQVNPTLIRVPDGFEIIRLVDRRQSQGATAAAP
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHH
KIVQTHVRHILLRVGEGKSEGQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
WISPGETVPEFERAMNALQDGQISQPIRTEYGYHLIQVVGRREAEGSVQQQMDIARQAIG
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QRKAEQAYADWLRELRDSSYVQYKIGGLPSN
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA