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The map label for this gene is actP [H]

Identifier: 161485705

GI number: 161485705

Start: 4910201

End: 4911928

Strand: Reverse

Name: actP [H]

Synonym: XAC4176

Alternate gene names: 161485705

Gene position: 4911928-4910201 (Counterclockwise)

Preceding gene: 21244894

Following gene: 21244892

Centisome position: 94.91

GC content: 64.24

Gene sequence:

>1728_bases
ATGAGCAAGATTTCGCGCCTTCTCCTGATTCTGGCCGGCCTGATGCCCGCCGGCATCGCACTGGCAGCCGGCGGCGACCT
GGGTCAGGTCGACAAGCAGCCCACCAACTGGGTGGCGATCGGCATGTTCGGCTTCTTCGTGCTGGCCACCCTGTGGATCA
CCAAATGGGCAGCGGCCAAGACCAAGTCGGCCGCTGACTTCTATACCGCTGGCGGTGGCATCACCGGTTTCCAGAACGGC
CTGGCGATCGCAGGCGACTTCATGTCGGCGGCCTCGTTCCTGGGCATCACCGCTGCGGTGATGGCCAACGGCTACGACGG
CCTGATCTATGCGATCGGTTTTCTGGTGGGCTGGCCGATCCTGACCTTCCTGATGGCCGAACGCCTGCGCAACCTCGGCA
AGTACACGTTTGCCGACGTGGCCGGTTACCGCTTCGCGCCGACGGCGATCCGCAGCTTTGCGGCGTCGGGCACGTTGGTG
GTGGTGCTGTTCTATCTGATCGCACAGATGGTCGGTGCCGGTGCGCTGATCAAGTTGCTGTTCGGCCTGGACTACTGGGT
GGCGGTGACCCTGGTCGGCGTGCTGATGATGATCTACGTGTTGTTCGGCGGCATGACCGCAACGACCTGGGTGCAGATCA
TCAAGGCCGTGCTGCTGCTGACCGGCGTGACCTTCATGGCCGTGGCGATCATGTGGCATTTCAACTTCAGCTTCGAGGCG
CTGTTTGCCGAAGGCGTGCGGGTCAAAACCGCGGTCGCGGCCAGCGGTGGCGCTTCGCCCGAGGATGCGGCAAAAGCAGG
CCTGTCGATCATGGGACCGGGCGGTTTCGTCAAGGACCCGATTTCGGCGATTTCCTTCGGCATGGCGCTGATGTTCGGTA
CCGCCGGCCTGCCGCACATCCTGATGCGCTTCTTCACCGTTCCCGATGCCAAGCAGGCGCGTAAGTCGGTGCTGTGGGCC
ACCACCTGGATCGGCTACTTCTACATCCTGATCTTCATCATCGGCTTCGGTGCGATCGCACTGGTGCTGACCAACCCGCA
GTTCGCCGATGTTGCCACCGGCACCATCCATGGCGGCAAGGGTGCGGCCAACATGGCGGCGGTGCTGGTCGGTAACGCCG
TGGGCGGCAACGTGTTCATGGGCTTCATCTCGGCAGTGGCCTTCGCCACCATCCTGGCGGTGGTGGCGGGCCTGACCCTG
TCCGGCGCCTCGGCGGTGTCGCATGACCTGTACGCCACGGTGATCAAGAAGGGCAACCCGGCGCCGGGCTCGGAGCTCAA
GGTCTCGCGTGCCACCACCCTGGTGCTGGGCGTGATCGCGGTGCTGCTGGGCATCGTGTTCGAGAAGCAGAATGTGGCCT
TCATGGTGTCGCTGGCGTTCGCCATCGCGGCCTCGGCCAACTTCCCGGTGCTGATCCTGTCGTTGTTGTGGAAGAACTGC
ACCACCCGTGGCGCAGTGATCGGCGGTTTCCTCGGCCTGATCTCTTCGCTGGTGCTGACGATCCTGTCGCCATCGGTGTG
GGTGGACACGCTGGGCAACGCGGCCGGCTCGGCGCCGTTCCCGTACACCTCGCCGGCGCTGTTCTCGATGACGATTGGCT
TTGTGGGCATCTGGTTGTTCTCCGTGCTGGATCGCAGCCCGCAGGCAGCCAACGAACGCGCCGCCTTCAAGGCGCAGCAG
ATCCGTGCCGAAACCGGCCTGGGTGCCAGTGGTGCGTCCGGTCACTGA

Upstream 100 bases:

>100_bases
GGGTGATGGTATTCACCATCGTCATCACCGCCATCTACGTGCGTCGCGCCAACAGCACCTACGACCAGCTGACCGCGCAG
ATCCTGGAGGAAGCCCGCAA

Downstream 100 bases:

>100_bases
TCGACCAGCGTCATTGTTGGTGTGATCGCAGACGCCGGCCCAGTGCCGGCGTTTTGCGTTTGGGCGAGGCGGCTTCGTTG
GTGATGCTTCAGCCGGACGA

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MSKISRLLLILAGLMPAGIALAAGGDLGQVDKQPTNWVAIGMFGFFVLATLWITKWAAAKTKSAADFYTAGGGITGFQNG
LAIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPILTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLV
VVLFYLIAQMVGAGALIKLLFGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEA
LFAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKQARKSVLWA
TTWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGKGAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTL
SGASAVSHDLYATVIKKGNPAPGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNC
TTRGAVIGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLFSVLDRSPQAANERAAFKAQQ
IRAETGLGASGASGH

Sequences:

>Translated_575_residues
MSKISRLLLILAGLMPAGIALAAGGDLGQVDKQPTNWVAIGMFGFFVLATLWITKWAAAKTKSAADFYTAGGGITGFQNG
LAIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPILTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLV
VVLFYLIAQMVGAGALIKLLFGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEA
LFAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKQARKSVLWA
TTWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGKGAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTL
SGASAVSHDLYATVIKKGNPAPGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNC
TTRGAVIGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLFSVLDRSPQAANERAAFKAQQ
IRAETGLGASGASGH
>Mature_574_residues
SKISRLLLILAGLMPAGIALAAGGDLGQVDKQPTNWVAIGMFGFFVLATLWITKWAAAKTKSAADFYTAGGGITGFQNGL
AIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPILTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLVV
VLFYLIAQMVGAGALIKLLFGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEAL
FAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKQARKSVLWAT
TWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGKGAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTLS
GASAVSHDLYATVIKKGNPAPGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNCT
TRGAVIGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLFSVLDRSPQAANERAAFKAQQI
RAETGLGASGASGH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=472, Percent_Identity=23.9406779661017, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790503, Length=572, Percent_Identity=62.7622377622378, Blast_Score=677, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=513, Percent_Identity=23.7816764132554, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59785; Mature: 59654

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SKISRLLLILAGLMPAGIALAAGGDLGQVDKQPTNWVAIGMFGFFVLATLWITKWAAAK
CHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHC
TKSAADFYTAGGGITGFQNGLAIAGDFMSAASFLGITAAVMANGYDGLIYAIGFLVGWPI
CCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LTFLMAERLRNLGKYTFADVAGYRFAPTAIRSFAASGTLVVVLFYLIAQMVGAGALIKLL
HHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHH
FGLDYWVAVTLVGVLMMIYVLFGGMTATTWVQIIKAVLLLTGVTFMAVAIMWHFNFSFEA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LFAEGVRVKTAVAASGGASPEDAAKAGLSIMGPGGFVKDPISAISFGMALMFGTAGLPHI
HHHCCCEEEEEEECCCCCCCHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LMRFFTVPDAKQARKSVLWATTWIGYFYILIFIIGFGAIALVLTNPQFADVATGTIHGGK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCHHHCCCCCCCCCC
GAANMAAVLVGNAVGGNVFMGFISAVAFATILAVVAGLTLSGASAVSHDLYATVIKKGNP
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
APGSELKVSRATTLVLGVIAVLLGIVFEKQNVAFMVSLAFAIAASANFPVLILSLLWKNC
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TTRGAVIGGFLGLISSLVLTILSPSVWVDTLGNAAGSAPFPYTSPALFSMTIGFVGIWLF
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SVLDRSPQAANERAAFKAQQIRAETGLGASGASGH
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA