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The map label for this gene is thrB

Identifier: 16127594

GI number: 16127594

Start: 3613858

End: 3614811

Strand: Direct

Name: thrB

Synonym: CC_3364

Alternate gene names: 16127594

Gene position: 3613858-3614811 (Clockwise)

Preceding gene: 16127591

Following gene: 16127595

Centisome position: 89.97

GC content: 67.4

Gene sequence:

>954_bases
ATGGCCGTCTATACCGACATCACCGACCAGGAACTCGAAGCCTTCCTCGAAGGCTATGACCTCGGCGCGCCGCTGGCGTT
CAAGGGCATCGCCGAGGGCGTGGAGAACTCCAACTTCCTGCTGGAGACGGAGAAGGGTCGCTACATCCTCACCGTCTACG
AGCGGCGGGTGAAGGCTGAAGACCTCCCGTACTTCCTCAACATGCTGACCTGGCTGGCCGATCGCGGCTATCCCAGCGCG
CGGCCGATCCCGACCCGCAGCGGCGCCACACTGTCGAGCCTGCGCGGCAAGCCCGCCGCCATCGTCGAGTTCCTGCCGGG
CCTTTCGGTGCGCAAGCCCACCGCCGCCCACTGCCGCGAGGCCGGCGAGGGCCTGGCGTGGCTGCATCTGGCCGGCGAGG
GCTATCCGGGCCGCCGCGCCAATGATCTTGGCCAAGCCGCCTGGTCGCCGCTGTTTTCCAAGCACCGCAAGGCCGCCGAG
GACCTCAAGCCGGGCCTCTCGGCGACGATCGACAACGACCTGGCGCAGCTCTCCTTGATGTGGCCGCGAAATCTGCCGAC
CGGGACGATCCACGCCGACTATTTCCCGGACAACGTCTTCTTCCAGTCGAACGGCAAGTTCGCCGCCGCGATCGACTTCT
ATTTCGCCTGCGACGACGCCTACGCCTACGACGTGGCCGTGACCCTGAACGCCTGGTGCTTCGAGGCCGACGGCAGCTTC
AACATCACCGCCGCCAAGGCGCTGCTGAACGGCTATGAGCGTCGCCGGCCGCTGAGCCCGATCGAGAAGGAAGCCCTGCC
GATCCTGGCGCGCGGCGCAGCGATGCGGTTCTTCCTGACCCGTCTGGCCGACTGGGGTTCGACCCCGGCCGGCGCGCTGG
TCAGGCCCAAGGACCCGCTAGAGTACGAGCGCAAGCTGGCCGTCCACCGCGAGGGTCTCGTGCTGTTCGCATGA

Upstream 100 bases:

>100_bases
ACAGTTTCAGGGCGATCATGGCGGCGCTCCAAACGTTAGAACAAACGTTATACCTCACCGCCCCCTTGACCGCCAGCGCC
CGCTCCCGCATCCCCGCGTC

Downstream 100 bases:

>100_bases
CGCCGAAGGTCACGATCTATACCGACGGCGCCTGCAAGGGGAATCCGGGCCCCGGCGGCTGGGGCGCCATCCTGTTCTAT
GGCGACAAGAAAAAGGAAAT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAVYTDITDQELEAFLEGYDLGAPLAFKGIAEGVENSNFLLETEKGRYILTVYERRVKAEDLPYFLNMLTWLADRGYPSA
RPIPTRSGATLSSLRGKPAAIVEFLPGLSVRKPTAAHCREAGEGLAWLHLAGEGYPGRRANDLGQAAWSPLFSKHRKAAE
DLKPGLSATIDNDLAQLSLMWPRNLPTGTIHADYFPDNVFFQSNGKFAAAIDFYFACDDAYAYDVAVTLNAWCFEADGSF
NITAAKALLNGYERRRPLSPIEKEALPILARGAAMRFFLTRLADWGSTPAGALVRPKDPLEYERKLAVHREGLVLFA

Sequences:

>Translated_317_residues
MAVYTDITDQELEAFLEGYDLGAPLAFKGIAEGVENSNFLLETEKGRYILTVYERRVKAEDLPYFLNMLTWLADRGYPSA
RPIPTRSGATLSSLRGKPAAIVEFLPGLSVRKPTAAHCREAGEGLAWLHLAGEGYPGRRANDLGQAAWSPLFSKHRKAAE
DLKPGLSATIDNDLAQLSLMWPRNLPTGTIHADYFPDNVFFQSNGKFAAAIDFYFACDDAYAYDVAVTLNAWCFEADGSF
NITAAKALLNGYERRRPLSPIEKEALPILARGAAMRFFLTRLADWGSTPAGALVRPKDPLEYERKLAVHREGLVLFA
>Mature_316_residues
AVYTDITDQELEAFLEGYDLGAPLAFKGIAEGVENSNFLLETEKGRYILTVYERRVKAEDLPYFLNMLTWLADRGYPSAR
PIPTRSGATLSSLRGKPAAIVEFLPGLSVRKPTAAHCREAGEGLAWLHLAGEGYPGRRANDLGQAAWSPLFSKHRKAAED
LKPGLSATIDNDLAQLSLMWPRNLPTGTIHADYFPDNVFFQSNGKFAAAIDFYFACDDAYAYDVAVTLNAWCFEADGSFN
ITAAKALLNGYERRRPLSPIEKEALPILARGAAMRFFLTRLADWGSTPAGALVRPKDPLEYERKLAVHREGLVLFA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_CAUCN (B8H4W6)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002518848.1
- ProteinModelPortal:   B8H4W6
- SMR:   B8H4W6
- GeneID:   7332472
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_03475
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 35025; Mature: 34894

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDITDQELEAFLEGYDLGAPLAFKGIAEGVENSNFLLETEKGRYILTVYERRVKAE
CEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHCCC
DLPYFLNMLTWLADRGYPSARPIPTRSGATLSSLRGKPAAIVEFLPGLSVRKPTAAHCRE
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCCHHHHHH
AGEGLAWLHLAGEGYPGRRANDLGQAAWSPLFSKHRKAAEDLKPGLSATIDNDLAQLSLM
HCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHEEEEE
WPRNLPTGTIHADYFPDNVFFQSNGKFAAAIDFYFACDDAYAYDVAVTLNAWCFEADGSF
CCCCCCCCEEEECCCCCCEEEECCCCEEEEEEEEEEECCCEEEEEEEEEEEEEEECCCCC
NITAAKALLNGYERRRPLSPIEKEALPILARGAAMRFFLTRLADWGSTPAGALVRPKDPL
CHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCH
EYERKLAVHREGLVLFA
HHHHHHHHHHCCEEEEC
>Mature Secondary Structure 
AVYTDITDQELEAFLEGYDLGAPLAFKGIAEGVENSNFLLETEKGRYILTVYERRVKAE
EEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHCCC
DLPYFLNMLTWLADRGYPSARPIPTRSGATLSSLRGKPAAIVEFLPGLSVRKPTAAHCRE
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCCHHHHHH
AGEGLAWLHLAGEGYPGRRANDLGQAAWSPLFSKHRKAAEDLKPGLSATIDNDLAQLSLM
HCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHEEEEE
WPRNLPTGTIHADYFPDNVFFQSNGKFAAAIDFYFACDDAYAYDVAVTLNAWCFEADGSF
CCCCCCCCEEEECCCCCCEEEECCCCEEEEEEEEEEECCCEEEEEEEEEEEEEEECCCCC
NITAAKALLNGYERRRPLSPIEKEALPILARGAAMRFFLTRLADWGSTPAGALVRPKDPL
CHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCH
EYERKLAVHREGLVLFA
HHHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA