Click here to switch to the map view.

The map label for this gene is ispH

Identifier: 16127591

GI number: 16127591

Start: 3611677

End: 3612636

Strand: Direct

Name: ispH

Synonym: CC_3361

Alternate gene names: 16127591

Gene position: 3611677-3612636 (Clockwise)

Preceding gene: 16127590

Following gene: 16127594

Centisome position: 89.91

GC content: 67.5

Gene sequence:

>960_bases
ATGAACGCTCAGACCCCGATCCGTCGCCCGATCTCCCTGGTTCTGGCCAGCCCGCGCGGTTTCTGCGCCGGCGTCGACCG
GGCCATCCAGATCGTCGAACGCGCCGTCGAGAAGTTCGGCGCGCCGGTCTATGTGCGCCACGAGATCGTCCACAACCGTC
ACGTGGTTGATCGCCTGAAGGCCCTGGGCGCGGTGTTCATCGAGGAGCTGGAAGAAGCGCCCGACGATCGCCCCGTCGTG
TTCTCGGCCCACGGCGTGCCCAAGTCGGTGCCCGCCGAGGCCAAGGCCCGCCAGATGATCTATCTGGACGCCACGTGCCC
GCTGGTTTCCAAGGTCCATGTCGAGGCTCAGAAGCACTATGACGCCGGCCGCGAGATCGTCCTGATCGGCCATGCCGGCC
ACCCCGAGGTGATCGGCACCATGGGCCAGCTGCCCGAGGGCGCAGTGACCCTCATCGAGGATCTGAAGGACGCGGCGGCC
TGGGAGCCCAAGGACGCCGCCAATGTCGCCTTCCTGACCCAGACCACCCTGTCGGTCGACGACACGGCGGACATGGTGGC
CTTGCTGCGCGAGCGCTTCCCCGGCATCGCCGCGCCGCACAAGGAAGACATCTGCTACGCCACCACCAACCGTCAGGACG
CGGTCAAGCATCTGGCCGAGCAGTCCGAACTGATCCTGGTGGTCGGCTCGAAGAACTCGTCGAACTCGGTGCGCCTCAAG
GAGGTCGGCCTGAAGGCCGGCGCCCGCGACGCGCATCTGATCGACGACGCCTCGGGGATCGACTGGACCTGGTTCGACGG
GATCTCGCGCGTGGGCCTCACCGCTGGGGCCTCGGCGCCGGAGGACCTGGTGCAGGGCGTCATCGACGCGATCTCGGCGC
GGTTCGACACCACGGTCGAGGAACTGGTCGAGGCGCGGGAGACGATCACGTTCAAGCTGCCGAGGTTGCTGACGGCTTAG

Upstream 100 bases:

>100_bases
CGCCCCGCCAGCGTCATGCAGCCTGATAAAGGCATATGCGTGACGTCGCAACGACGCAGACTCCTGGCGAACGGACCGGC
GAGACGCTAGGTTCCCCGCC

Downstream 100 bases:

>100_bases
GGTGGTGAGCGGCTGTTGATCTACAACCATTCGACCTTCCAACCGGACTCGATGAAGTACCCGACAAGCTCATCGTGATC
CGCTACCCAGCCGTCGAAGC

Product: LytB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNAQTPIRRPISLVLASPRGFCAGVDRAIQIVERAVEKFGAPVYVRHEIVHNRHVVDRLKALGAVFIEELEEAPDDRPVV
FSAHGVPKSVPAEAKARQMIYLDATCPLVSKVHVEAQKHYDAGREIVLIGHAGHPEVIGTMGQLPEGAVTLIEDLKDAAA
WEPKDAANVAFLTQTTLSVDDTADMVALLRERFPGIAAPHKEDICYATTNRQDAVKHLAEQSELILVVGSKNSSNSVRLK
EVGLKAGARDAHLIDDASGIDWTWFDGISRVGLTAGASAPEDLVQGVIDAISARFDTTVEELVEARETITFKLPRLLTA

Sequences:

>Translated_319_residues
MNAQTPIRRPISLVLASPRGFCAGVDRAIQIVERAVEKFGAPVYVRHEIVHNRHVVDRLKALGAVFIEELEEAPDDRPVV
FSAHGVPKSVPAEAKARQMIYLDATCPLVSKVHVEAQKHYDAGREIVLIGHAGHPEVIGTMGQLPEGAVTLIEDLKDAAA
WEPKDAANVAFLTQTTLSVDDTADMVALLRERFPGIAAPHKEDICYATTNRQDAVKHLAEQSELILVVGSKNSSNSVRLK
EVGLKAGARDAHLIDDASGIDWTWFDGISRVGLTAGASAPEDLVQGVIDAISARFDTTVEELVEARETITFKLPRLLTA
>Mature_319_residues
MNAQTPIRRPISLVLASPRGFCAGVDRAIQIVERAVEKFGAPVYVRHEIVHNRHVVDRLKALGAVFIEELEEAPDDRPVV
FSAHGVPKSVPAEAKARQMIYLDATCPLVSKVHVEAQKHYDAGREIVLIGHAGHPEVIGTMGQLPEGAVTLIEDLKDAAA
WEPKDAANVAFLTQTTLSVDDTADMVALLRERFPGIAAPHKEDICYATTNRQDAVKHLAEQSELILVVGSKNSSNSVRLK
EVGLKAGARDAHLIDDASGIDWTWFDGISRVGLTAGASAPEDLVQGVIDAISARFDTTVEELVEARETITFKLPRLLTA

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family

Homologues:

Organism=Escherichia coli, GI1786212, Length=309, Percent_Identity=54.3689320388349, Blast_Score=330, Evalue=7e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISPH_CAUCR (Q9A345)

Other databases:

- EMBL:   AE005673
- PIR:   G87665
- RefSeq:   NP_422155.1
- GeneID:   940857
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_3361
- NMPDR:   fig|190650.1.peg.3335
- TIGR:   CC_3361
- HOGENOM:   HBG335228
- OMA:   WGAPVYV
- ProtClustDB:   CLSK891439
- BRENDA:   1.17.1.2
- HAMAP:   MF_00191
- InterPro:   IPR003451
- TIGRFAMs:   TIGR00216

Pfam domain/function: PF02401 LYTB

EC number: =1.17.1.2

Molecular weight: Translated: 34579; Mature: 34579

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQTPIRRPISLVLASPRGFCAGVDRAIQIVERAVEKFGAPVYVRHEIVHNRHVVDRLK
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHH
ALGAVFIEELEEAPDDRPVVFSAHGVPKSVPAEAKARQMIYLDATCPLVSKVHVEAQKHY
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHCCEEEEEECCCCHHHHHHHHHHHHC
DAGREIVLIGHAGHPEVIGTMGQLPEGAVTLIEDLKDAAAWEPKDAANVAFLTQTTLSVD
CCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCC
DTADMVALLRERFPGIAAPHKEDICYATTNRQDAVKHLAEQSELILVVGSKNSSNSVRLK
CHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
EVGLKAGARDAHLIDDASGIDWTWFDGISRVGLTAGASAPEDLVQGVIDAISARFDTTVE
ECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELVEARETITFKLPRLLTA
HHHHHHHHHEEECCHHHCC
>Mature Secondary Structure
MNAQTPIRRPISLVLASPRGFCAGVDRAIQIVERAVEKFGAPVYVRHEIVHNRHVVDRLK
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHH
ALGAVFIEELEEAPDDRPVVFSAHGVPKSVPAEAKARQMIYLDATCPLVSKVHVEAQKHY
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHCCEEEEEECCCCHHHHHHHHHHHHC
DAGREIVLIGHAGHPEVIGTMGQLPEGAVTLIEDLKDAAAWEPKDAANVAFLTQTTLSVD
CCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCC
DTADMVALLRERFPGIAAPHKEDICYATTNRQDAVKHLAEQSELILVVGSKNSSNSVRLK
CHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
EVGLKAGARDAHLIDDASGIDWTWFDGISRVGLTAGASAPEDLVQGVIDAISARFDTTVE
ECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELVEARETITFKLPRLLTA
HHHHHHHHHEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647