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The map label for this gene is cysJ [H]

Identifier: 16127293

GI number: 16127293

Start: 3288478

End: 3289992

Strand: Direct

Name: cysJ [H]

Synonym: CC_3063

Alternate gene names: 16127293

Gene position: 3288478-3289992 (Clockwise)

Preceding gene: 16127292

Following gene: 16127295

Centisome position: 81.87

GC content: 73.73

Gene sequence:

>1515_bases
ATGCCCGACCTCGCCTTCCTCCCGCCTGAGGCCCGGCGTTGGGTCTGGGCAGGCGTCGTCGTGGCGCTGTACGCCCTGTT
CTGCCTGGCCATCGCCCTGCGCGAAGCCTGGCGCGGCCGCCAGGCGCGCAAGGCCGCCGACGCCCTTTCTCAAGGCTCCG
GCGAGCCGGTGCTCGTCGCCTACGCCAGCCAGACAGGCTTCGCCGAGGAGTTGGCGACGGCCACAGCCAAGGCCCTGGCG
GACACCGGCGCGCCGGTGACCCTGAAGGACCTCTCGGCCGTCACCGCCGGCGACCTTGCGGGCCGCGCCCTGTTCGTGGT
CAGCACCACCGGCGAGGGCGACGCTCCCGACCCGGCCCGCGCCTTCATCCGCGACGTGATGAAGGACGAAGCTGACCTTT
CGGCCCTGCGCTACGGCGTGCTGGCCCTGGGCGATTCCAGCTACGCCCACTACTGCGCCTTCGGGCGGTCGCTGGACGCC
TGGCTGTCGGGCCGGGGCGGCCAGCCGCTGTTCGACCGCGTGGAGGTCGACGACGCCGATCCGGCCGCCCTGCGCCACTG
GCAGGGACAGCTCGCAACCCTGACCGGCGTCACCGACGCGCCCGACTGGACGCGGCCGACCTATGACGCCTGGACCCTGG
CCGAGCGGACGCTGCTGAACCCCGGCAGCCCCGGCGGCGAGGCCTGGCATCTGCGCCTGACGCCGCCCAAGGGCGCGGTC
TGGCAAGCCGGCGACATTGTCGAGATCGGCCCGCGCAACGACCCCGCGCAGGTCGCCGCCCTGATCGCGGCGCTGGACCT
TCCCGCCGAAGCCGCCGACACCCTGGCGGGTCTTCGCCTGCCGCAGGACGCGGCCGCCCTCGACGCCCTGCGCGGCCTAC
CGCTCGAAGCCCTGGCCGAGCGCCTGACCGCCCTGCCCCATCGCGAATACTCGATCGCCTCGCTGCCCGACGACGGCGGC
GTCGAGCTGATCGTCCGGCTGATGACCCGCGCCGACGGGGCGCCGGGCCTGGGCTCGGGCTGGCTGTGCCGCCATGCGCC
GATCGGCGCGGCGATCGAGGCCCGGGTGCGCGTCAACCGCAGCTTCCACGCGCCCGAGACCAAGCGGCCGCTGATCCTGA
TCGGTTCGGGCACGGGTCTGGCGGGCCTGCGCGCGCACCTGAAGGCCCGGGCCGCCGCCGGCGTGCGCTGGAACTGGCTG
ATCTTCGGCGAGCGCACCGCCGCCCACGACTATTTCCACCGCGCCGAACTGGAAGCCTGGCAGGCCTCGGGCCTGCTGGA
CCGGCTGGACCTGGCCTTCTCCCGCGACCAGGCCGAGCGGGTCTATGTTCAGCACCGCCTGCGGGAGTCGGCCGACATCC
TGCGCCGCTGGGTGGCCAACGGCGCGGCGATCTATGTCTGCGGGTCGCTGGAAGGCATGTCGCGCGAGGCCCACACGGCG
CTCGTCGAAATCCTCGGCGCGCCGATGCTGGAGCGCCTGACCGACGAGGGGCGGTATCGGCGGGACGTGTACTAG

Upstream 100 bases:

>100_bases
CCTTCGCCGCCGCCCACGATCTGGCCGCCCTGATCGTCAGCCGAGGCCCGTCCGGTCTTGAGGAACGGCTGTCGCCCGCC
CTGCAGGCGATGCTGGACTG

Downstream 100 bases:

>100_bases
CTTGTCATCCCGGAAAGCCCGCAGGGCTTATCCGGGACCCAGGGGCGGCCGGCGCGGCGCTCTTTCACCCCCTGGGTCCC
GGCGCTCCGCGCTTTGCGCT

Product: sulfite reductase (NADPH) flavoprotein alpha-component

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MPDLAFLPPEARRWVWAGVVVALYALFCLAIALREAWRGRQARKAADALSQGSGEPVLVAYASQTGFAEELATATAKALA
DTGAPVTLKDLSAVTAGDLAGRALFVVSTTGEGDAPDPARAFIRDVMKDEADLSALRYGVLALGDSSYAHYCAFGRSLDA
WLSGRGGQPLFDRVEVDDADPAALRHWQGQLATLTGVTDAPDWTRPTYDAWTLAERTLLNPGSPGGEAWHLRLTPPKGAV
WQAGDIVEIGPRNDPAQVAALIAALDLPAEAADTLAGLRLPQDAAALDALRGLPLEALAERLTALPHREYSIASLPDDGG
VELIVRLMTRADGAPGLGSGWLCRHAPIGAAIEARVRVNRSFHAPETKRPLILIGSGTGLAGLRAHLKARAAAGVRWNWL
IFGERTAAHDYFHRAELEAWQASGLLDRLDLAFSRDQAERVYVQHRLRESADILRRWVANGAAIYVCGSLEGMSREAHTA
LVEILGAPMLERLTDEGRYRRDVY

Sequences:

>Translated_504_residues
MPDLAFLPPEARRWVWAGVVVALYALFCLAIALREAWRGRQARKAADALSQGSGEPVLVAYASQTGFAEELATATAKALA
DTGAPVTLKDLSAVTAGDLAGRALFVVSTTGEGDAPDPARAFIRDVMKDEADLSALRYGVLALGDSSYAHYCAFGRSLDA
WLSGRGGQPLFDRVEVDDADPAALRHWQGQLATLTGVTDAPDWTRPTYDAWTLAERTLLNPGSPGGEAWHLRLTPPKGAV
WQAGDIVEIGPRNDPAQVAALIAALDLPAEAADTLAGLRLPQDAAALDALRGLPLEALAERLTALPHREYSIASLPDDGG
VELIVRLMTRADGAPGLGSGWLCRHAPIGAAIEARVRVNRSFHAPETKRPLILIGSGTGLAGLRAHLKARAAAGVRWNWL
IFGERTAAHDYFHRAELEAWQASGLLDRLDLAFSRDQAERVYVQHRLRESADILRRWVANGAAIYVCGSLEGMSREAHTA
LVEILGAPMLERLTDEGRYRRDVY
>Mature_503_residues
PDLAFLPPEARRWVWAGVVVALYALFCLAIALREAWRGRQARKAADALSQGSGEPVLVAYASQTGFAEELATATAKALAD
TGAPVTLKDLSAVTAGDLAGRALFVVSTTGEGDAPDPARAFIRDVMKDEADLSALRYGVLALGDSSYAHYCAFGRSLDAW
LSGRGGQPLFDRVEVDDADPAALRHWQGQLATLTGVTDAPDWTRPTYDAWTLAERTLLNPGSPGGEAWHLRLTPPKGAVW
QAGDIVEIGPRNDPAQVAALIAALDLPAEAADTLAGLRLPQDAAALDALRGLPLEALAERLTALPHREYSIASLPDDGGV
ELIVRLMTRADGAPGLGSGWLCRHAPIGAAIEARVRVNRSFHAPETKRPLILIGSGTGLAGLRAHLKARAAAGVRWNWLI
FGERTAAHDYFHRAELEAWQASGLLDRLDLAFSRDQAERVYVQHRLRESADILRRWVANGAAIYVCGSLEGMSREAHTAL
VEILGAPMLERLTDEGRYRRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=238, Percent_Identity=32.3529411764706, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI169790958, Length=261, Percent_Identity=29.1187739463602, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI169790956, Length=261, Percent_Identity=29.1187739463602, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7657393, Length=217, Percent_Identity=33.6405529953917, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI221316709, Length=212, Percent_Identity=33.9622641509434, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI221316705, Length=226, Percent_Identity=32.3008849557522, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI221316707, Length=180, Percent_Identity=36.1111111111111, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI24041029, Length=235, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI10835173, Length=225, Percent_Identity=29.3333333333333, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789123, Length=536, Percent_Identity=28.3582089552239, Blast_Score=171, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17566446, Length=220, Percent_Identity=30.4545454545455, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17554134, Length=203, Percent_Identity=31.5270935960591, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531441, Length=127, Percent_Identity=37.007874015748, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32563863, Length=127, Percent_Identity=37.007874015748, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321143, Length=235, Percent_Identity=25.9574468085106, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6325305, Length=201, Percent_Identity=28.8557213930348, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321832, Length=174, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17137192, Length=236, Percent_Identity=30.5084745762712, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24582192, Length=236, Percent_Identity=30.5084745762712, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24660907, Length=228, Percent_Identity=28.0701754385965, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660903, Length=228, Percent_Identity=28.0701754385965, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583543, Length=257, Percent_Identity=29.1828793774319, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI78706876, Length=257, Percent_Identity=29.1828793774319, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI78706872, Length=257, Percent_Identity=29.1828793774319, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 54240; Mature: 54109

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLAFLPPEARRWVWAGVVVALYALFCLAIALREAWRGRQARKAADALSQGSGEPVLVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
YASQTGFAEELATATAKALADTGAPVTLKDLSAVTAGDLAGRALFVVSTTGEGDAPDPAR
EECCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHH
AFIRDVMKDEADLSALRYGVLALGDSSYAHYCAFGRSLDAWLSGRGGQPLFDRVEVDDAD
HHHHHHHHCHHHHHHHHHHHEEECCCCCHHHHHHCCCHHHHHCCCCCCCCHHCCCCCCCC
PAALRHWQGQLATLTGVTDAPDWTRPTYDAWTLAERTLLNPGSPGGEAWHLRLTPPKGAV
HHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
WQAGDIVEIGPRNDPAQVAALIAALDLPAEAADTLAGLRLPQDAAALDALRGLPLEALAE
CCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
RLTALPHREYSIASLPDDGGVELIVRLMTRADGAPGLGSGWLCRHAPIGAAIEARVRVNR
HHHHCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECC
SFHAPETKRPLILIGSGTGLAGLRAHLKARAAAGVRWNWLIFGERTAAHDYFHRAELEAW
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHH
QASGLLDRLDLAFSRDQAERVYVQHRLRESADILRRWVANGAAIYVCGSLEGMSREAHTA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
LVEILGAPMLERLTDEGRYRRDVY
HHHHHCCHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
PDLAFLPPEARRWVWAGVVVALYALFCLAIALREAWRGRQARKAADALSQGSGEPVLVA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
YASQTGFAEELATATAKALADTGAPVTLKDLSAVTAGDLAGRALFVVSTTGEGDAPDPAR
EECCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHH
AFIRDVMKDEADLSALRYGVLALGDSSYAHYCAFGRSLDAWLSGRGGQPLFDRVEVDDAD
HHHHHHHHCHHHHHHHHHHHEEECCCCCHHHHHHCCCHHHHHCCCCCCCCHHCCCCCCCC
PAALRHWQGQLATLTGVTDAPDWTRPTYDAWTLAERTLLNPGSPGGEAWHLRLTPPKGAV
HHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
WQAGDIVEIGPRNDPAQVAALIAALDLPAEAADTLAGLRLPQDAAALDALRGLPLEALAE
CCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
RLTALPHREYSIASLPDDGGVELIVRLMTRADGAPGLGSGWLCRHAPIGAAIEARVRVNR
HHHHCCCCCCEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECC
SFHAPETKRPLILIGSGTGLAGLRAHLKARAAAGVRWNWLIFGERTAAHDYFHRAELEAW
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHH
QASGLLDRLDLAFSRDQAERVYVQHRLRESADILRRWVANGAAIYVCGSLEGMSREAHTA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
LVEILGAPMLERLTDEGRYRRDVY
HHHHHCCHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA