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The map label for this gene is cobQ [H]

Identifier: 16125995

GI number: 16125995

Start: 1927340

End: 1928794

Strand: Direct

Name: cobQ [H]

Synonym: CC_1751

Alternate gene names: 16125995

Gene position: 1927340-1928794 (Clockwise)

Preceding gene: 16125994

Following gene: 16125997

Centisome position: 47.98

GC content: 70.58

Gene sequence:

>1455_bases
ATGGCCGCCTTGATGATCCAGGGCTGCGGCTCGGATGTCGGAAAGTCGGTGCTGGTCGCCGGCCTGTGCCGGGTGTTCGC
CAATCGCGGCTTCGCGGTGCGGCCCTTCAAGCCTCAGAACATGTCGAACAACGCCGCCGTCACCGCAGACGGCGGCGAGA
TCGGCCGCGCCCAGGCCCTGCAGGCGATCGCCTGTCGGACGGCGCCGACGGTCGACATGAACCCCGTGCTGCTCAAGCCG
CAGAGCGATATCGGCGCGCAGGTGGTGGTGCGCGGGCGGATGGCGGGGTCCTGGGCGGCGCGCGGCTATCAGGACCACAA
GGCTAGCCTGCTGCCGACCGTGGTGGAGAGCTTTCGCACGCTGGAACGCCAGAGCGATCTGGTCATCGTCGAGGGGGCCG
GCAGCCCGGCTGAGATCAACCTTCGGGTCGGCGACATCGCCAATATGGGCTTCGCCCGCGCCGCCGACGTGCCGGTCGTC
CTGGTCGGCGATATCGACCGGGGCCATGTGATCGCCGCGCTCGTCGGGGCGCACGCCGTGCTCGATCCGGAGGATCGGGC
GATGATCAAGGGCTTCCTGATCAACAAGTTTCGCGGCGATCCGGCCCTGTTCGACGACGGTCGGCGGGCGATCGTGGAGC
GCACCGGCTGGGCCGACCTTGGCATGGCGCCGTGGCTGGCGGCGGCGCGCCGGCTCCCGGCCGAGGACGCGGTTGTGCTG
GACGCGCGTTCGGCCGGGCGTGGCGGCAAGGTCCGCATCGTCGTTCCAATGCTCTCCCGCATCGCCAATTTCGACGAGTT
CGACGCGCTGCGCGCTGAGCCTGGGGTCGAGTTCGCCTTCGTGCCGCCAGGCTCGGCGCTGCCGGGCGACGCCGACCTGG
TGATCCTGCCCGGCACGAAGGCCACGCGGGCGGATCTCGACTTTGTTCGCGCCCAGGGCTGGGACATCGACCTGCGTGCC
CATCTGCGGCGCGGCGGCCGCGTGCTGGGGATCTGCGGCGGCTATCAGATGCTGGGCCGGCGCGTGGCCGATCCCGACGG
CGTCGAGGGCGCGCCGGGGACTTCGGAAGGCCTTGGCCTGCTCGACGTCGAAACCGTGATGACCGGCGACAAGACCTTGC
GGCCGGTCACGGGCCGCCTGGACGGCTGCGCGCGCTTCGAGGGGTATGAGATGCATGTCGGCCGCACGTCTGGCGCGGCG
CGACCGATGTTGATCTTTGACACGGGTGAGCCGGACGGCGCCGTTTCGGCGGACGGGCGGATCAGCGGCTGCTACGTCCA
CGGCCTGTTCGATCGCGGTGAGGCCCGCGCGGCGCTTCTGGCGGCGCTGGGCGCGGTCTCGGACGCCGTCAATCAGGCCG
CGCGCGTGGATCTGGCCCTCGACGAGATCGCGGCGGTCCTGGAGCAATCGTTCGACATTCCGGCCCTGGCCAAACTGGCC
GGACTGTCGCTCTAG

Upstream 100 bases:

>100_bases
GTGGCGCGTTCCTGGGTCTGCGGGCGCGCTTCTAGGGATGGGAGGGGCGGGGGGCTGTGTCCCTCGCCCCCGGCCACCTT
GTCTTGGAGGAAAGCAGCGC

Downstream 100 bases:

>100_bases
GTCGCGGGCGCGAGGTCGATCCGCACCAGTTTCCAACGGAACAGGCCTTGCCGCTCCAGCGTGAGACCAAATGCGGGCTC
GTCCGGCTTGGCTTTGTCGC

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MAALMIQGCGSDVGKSVLVAGLCRVFANRGFAVRPFKPQNMSNNAAVTADGGEIGRAQALQAIACRTAPTVDMNPVLLKP
QSDIGAQVVVRGRMAGSWAARGYQDHKASLLPTVVESFRTLERQSDLVIVEGAGSPAEINLRVGDIANMGFARAADVPVV
LVGDIDRGHVIAALVGAHAVLDPEDRAMIKGFLINKFRGDPALFDDGRRAIVERTGWADLGMAPWLAAARRLPAEDAVVL
DARSAGRGGKVRIVVPMLSRIANFDEFDALRAEPGVEFAFVPPGSALPGDADLVILPGTKATRADLDFVRAQGWDIDLRA
HLRRGGRVLGICGGYQMLGRRVADPDGVEGAPGTSEGLGLLDVETVMTGDKTLRPVTGRLDGCARFEGYEMHVGRTSGAA
RPMLIFDTGEPDGAVSADGRISGCYVHGLFDRGEARAALLAALGAVSDAVNQAARVDLALDEIAAVLEQSFDIPALAKLA
GLSL

Sequences:

>Translated_484_residues
MAALMIQGCGSDVGKSVLVAGLCRVFANRGFAVRPFKPQNMSNNAAVTADGGEIGRAQALQAIACRTAPTVDMNPVLLKP
QSDIGAQVVVRGRMAGSWAARGYQDHKASLLPTVVESFRTLERQSDLVIVEGAGSPAEINLRVGDIANMGFARAADVPVV
LVGDIDRGHVIAALVGAHAVLDPEDRAMIKGFLINKFRGDPALFDDGRRAIVERTGWADLGMAPWLAAARRLPAEDAVVL
DARSAGRGGKVRIVVPMLSRIANFDEFDALRAEPGVEFAFVPPGSALPGDADLVILPGTKATRADLDFVRAQGWDIDLRA
HLRRGGRVLGICGGYQMLGRRVADPDGVEGAPGTSEGLGLLDVETVMTGDKTLRPVTGRLDGCARFEGYEMHVGRTSGAA
RPMLIFDTGEPDGAVSADGRISGCYVHGLFDRGEARAALLAALGAVSDAVNQAARVDLALDEIAAVLEQSFDIPALAKLA
GLSL
>Mature_483_residues
AALMIQGCGSDVGKSVLVAGLCRVFANRGFAVRPFKPQNMSNNAAVTADGGEIGRAQALQAIACRTAPTVDMNPVLLKPQ
SDIGAQVVVRGRMAGSWAARGYQDHKASLLPTVVESFRTLERQSDLVIVEGAGSPAEINLRVGDIANMGFARAADVPVVL
VGDIDRGHVIAALVGAHAVLDPEDRAMIKGFLINKFRGDPALFDDGRRAIVERTGWADLGMAPWLAAARRLPAEDAVVLD
ARSAGRGGKVRIVVPMLSRIANFDEFDALRAEPGVEFAFVPPGSALPGDADLVILPGTKATRADLDFVRAQGWDIDLRAH
LRRGGRVLGICGGYQMLGRRVADPDGVEGAPGTSEGLGLLDVETVMTGDKTLRPVTGRLDGCARFEGYEMHVGRTSGAAR
PMLIFDTGEPDGAVSADGRISGCYVHGLFDRGEARAALLAALGAVSDAVNQAARVDLALDEIAAVLEQSFDIPALAKLAG
LSL

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 50783; Mature: 50652

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALMIQGCGSDVGKSVLVAGLCRVFANRGFAVRPFKPQNMSNNAAVTADGGEIGRAQAL
CCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECCCCCCHHHHH
QAIACRTAPTVDMNPVLLKPQSDIGAQVVVRGRMAGSWAARGYQDHKASLLPTVVESFRT
HHHHHCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHH
LERQSDLVIVEGAGSPAEINLRVGDIANMGFARAADVPVVLVGDIDRGHVIAALVGAHAV
HHCCCCEEEEECCCCCEEEEEEECCCCCCCCCHHCCCCEEEEECCCCCHHHHHHHHHHHE
LDPEDRAMIKGFLINKFRGDPALFDDGRRAIVERTGWADLGMAPWLAAARRLPAEDAVVL
ECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEHHCCCCCCCCHHHHHHHHHCCCCCCEEEE
DARSAGRGGKVRIVVPMLSRIANFDEFDALRAEPGVEFAFVPPGSALPGDADLVILPGTK
EECCCCCCCEEEEEHHHHHHHCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCC
ATRADLDFVRAQGWDIDLRAHLRRGGRVLGICGGYQMLGRRVADPDGVEGAPGTSEGLGL
CCCCCHHHHHHCCCCEEHHHHHHCCCEEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCE
LDVETVMTGDKTLRPVTGRLDGCARFEGYEMHVGRTSGAARPMLIFDTGEPDGAVSADGR
EEEHEEECCCCEECCCCCCCCCCEECCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCE
ISGCYVHGLFDRGEARAALLAALGAVSDAVNQAARVDLALDEIAAVLEQSFDIPALAKLA
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GLSL
CCCC
>Mature Secondary Structure 
AALMIQGCGSDVGKSVLVAGLCRVFANRGFAVRPFKPQNMSNNAAVTADGGEIGRAQAL
CEEEEECCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECCCCCCHHHHH
QAIACRTAPTVDMNPVLLKPQSDIGAQVVVRGRMAGSWAARGYQDHKASLLPTVVESFRT
HHHHHCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHH
LERQSDLVIVEGAGSPAEINLRVGDIANMGFARAADVPVVLVGDIDRGHVIAALVGAHAV
HHCCCCEEEEECCCCCEEEEEEECCCCCCCCCHHCCCCEEEEECCCCCHHHHHHHHHHHE
LDPEDRAMIKGFLINKFRGDPALFDDGRRAIVERTGWADLGMAPWLAAARRLPAEDAVVL
ECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEHHCCCCCCCCHHHHHHHHHCCCCCCEEEE
DARSAGRGGKVRIVVPMLSRIANFDEFDALRAEPGVEFAFVPPGSALPGDADLVILPGTK
EECCCCCCCEEEEEHHHHHHHCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCC
ATRADLDFVRAQGWDIDLRAHLRRGGRVLGICGGYQMLGRRVADPDGVEGAPGTSEGLGL
CCCCCHHHHHHCCCCEEHHHHHHCCCEEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCE
LDVETVMTGDKTLRPVTGRLDGCARFEGYEMHVGRTSGAARPMLIFDTGEPDGAVSADGR
EEEHEEECCCCEECCCCCCCCCCEECCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCE
ISGCYVHGLFDRGEARAALLAALGAVSDAVNQAARVDLALDEIAAVLEQSFDIPALAKLA
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GLSL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA