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The map label for this gene is mcpA [H]

Identifier: 16124683

GI number: 16124683

Start: 443064

End: 444677

Strand: Direct

Name: mcpA [H]

Synonym: CC_0428

Alternate gene names: 16124683

Gene position: 443064-444677 (Clockwise)

Preceding gene: 16124682

Following gene: 16124685

Centisome position: 11.03

GC content: 67.29

Gene sequence:

>1614_bases
ATGGGGACCGCCATGAACCAGGACTACGCGATCGGTGAACGGACCGCGTTCATGGGCATCGACGACAAGGCGCGATCGGC
GCTGCGCGACCTGCGCCCTGTTATTCGGGCCGAGATCGGCAAGGCGCTCGACAACTTCTACGGCAAGGTCCGGGCGACCC
CCGAGACGCGCAAGTTCTTCAGTGACGACCGACATATGAACGCGGCGAGTTCGCGGCAGCAGGCGCACTGGGGCGTGATC
GCCGAAGGACAGTTCAGCGACGACTACGTGCAGGCGGTGCGAGCGATCGGCCAGACCCATGCCCGCATCGGCCTGGAGCC
GCGCTGGTACATCGGCGGCTATGCCGTCGTCGGCGACCATCTGGTTCGCGCAGTGATCGACTCGATGTGGCCCAGGGGGC
TGCTGGCCAAGGGCGGCTCTGACCGCGCGGGCGAGGCGGTCGCCGCCCTGATGAAGGCGATCTTCCTGGACATGGACTTC
GCCATCTCGATCTATCTTGAAACCCTGGAGAACGAGCGGCAACGCCTGGAGGCCGAGCAGAAGGCCACCCGAGCGCGTCA
GGAGCACGTCGTCACCCTCCTGGCCGAAGCGCTGGACCGCCTCGCCGCCGGCGACTTGCTGGCGAGGATCGATGGTGAGG
TCTGCAGCGAATTCGAGAAGCTCAAGGCCGACTTCAACCACGCCGTGGAGCTTCTGGATCAAGCGATGTGCGGCGTCGGC
GGCGCGACGGAGGGCATCCGCTCCAGCACCGAGGAAATCAGTGTCGCGGCCGACGACCTGTCGCGTCGCACCGAACAGCA
GGCCGCCAGCCTCGAGCAGACGGCCGCCGCCTTGGACGAGATCACCGCCACCGTCCGGCGCTCAGCGGCCGGCGCCAAAC
AGGCGCAGGAGGTCGTGGCCGGCGCCAAGACCGAAGCCGAGCGATCGGGCTCGGTCGTCAATCAGGCCGTCGCGGCGATG
GGTGAGATCGAGACAAGCTCCCGCGAGATCGGCAACATCATCGGGGTGATCGACGAGATCGCCTTCCAGACCAACCTCCT
GGCCCTGAACGCGGGGGTCGAGGCGGCCCGCGCCGGCGAGGCCGGCAGAGGTTTCGCGGTGGTCGCTCAGGAGGTTCGGG
CGTTGGCGCAGCGCTCGGCCGACGCGGCCAAGGAGATTAAGGCGCTGATCAATACCTCGACCAAGCAGGTCGAGGCGGGC
GTCGCCTTGGTGGGCCAGACGGGGGACGCGTTGCGCGGCATCGTCTCGAAGGTCGCCGAGATCGATGAGCTGATCGCGCA
GATCTCCGTCTCGGCGCAGGAGCAGTCTGGCGGACTGCATGAAGTCAACACCGCCGTGAACCAGATGGATCAGGTGACCC
AGCAGAACGCGGCGATGGTCGAGCAGACCACGGCGGCGACCCATTCGCTGAAGAGTCAGACAGGAGAACTGGTGAGGCAG
GTGGAGACCTTCCGGACCTCCGAGGGGCGACGTTCCTCTGCGGCGGCATCTCCGGCTCCCGTCCAGATGGCGCAACCGGC
TCGCTCGCCGCGTCCGCAGAGCCGGCCGGGCGGACCGCCGATCTCACGGGGCGCTACGGCGGTCGCGGTCAAGGAAGAGT
GGGAAGAATTCTAG

Upstream 100 bases:

>100_bases
TTGCAACCTGAGCGGGGGTGCGGCGAGGCGCCGCACTCGCTGCGAGAATATTTAAGCGCTCATTAGGGATAAGGGTCCGA
GGATTTCCCCAAGCGAAACA

Downstream 100 bases:

>100_bases
CGCGCGGACCCTCGAGCGCCCTGGGTTCAGGCATGTTCGCTTAGACCGTACGAACGCGCTCAGCAGATTTGGTTCGGGAG
CTTCTCGACAGCGGGGCCGT

Product: methyl-accepting chemotaxis protein McpB

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MGTAMNQDYAIGERTAFMGIDDKARSALRDLRPVIRAEIGKALDNFYGKVRATPETRKFFSDDRHMNAASSRQQAHWGVI
AEGQFSDDYVQAVRAIGQTHARIGLEPRWYIGGYAVVGDHLVRAVIDSMWPRGLLAKGGSDRAGEAVAALMKAIFLDMDF
AISIYLETLENERQRLEAEQKATRARQEHVVTLLAEALDRLAAGDLLARIDGEVCSEFEKLKADFNHAVELLDQAMCGVG
GATEGIRSSTEEISVAADDLSRRTEQQAASLEQTAAALDEITATVRRSAAGAKQAQEVVAGAKTEAERSGSVVNQAVAAM
GEIETSSREIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSADAAKEIKALINTSTKQVEAG
VALVGQTGDALRGIVSKVAEIDELIAQISVSAQEQSGGLHEVNTAVNQMDQVTQQNAAMVEQTTAATHSLKSQTGELVRQ
VETFRTSEGRRSSAAASPAPVQMAQPARSPRPQSRPGGPPISRGATAVAVKEEWEEF

Sequences:

>Translated_537_residues
MGTAMNQDYAIGERTAFMGIDDKARSALRDLRPVIRAEIGKALDNFYGKVRATPETRKFFSDDRHMNAASSRQQAHWGVI
AEGQFSDDYVQAVRAIGQTHARIGLEPRWYIGGYAVVGDHLVRAVIDSMWPRGLLAKGGSDRAGEAVAALMKAIFLDMDF
AISIYLETLENERQRLEAEQKATRARQEHVVTLLAEALDRLAAGDLLARIDGEVCSEFEKLKADFNHAVELLDQAMCGVG
GATEGIRSSTEEISVAADDLSRRTEQQAASLEQTAAALDEITATVRRSAAGAKQAQEVVAGAKTEAERSGSVVNQAVAAM
GEIETSSREIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSADAAKEIKALINTSTKQVEAG
VALVGQTGDALRGIVSKVAEIDELIAQISVSAQEQSGGLHEVNTAVNQMDQVTQQNAAMVEQTTAATHSLKSQTGELVRQ
VETFRTSEGRRSSAAASPAPVQMAQPARSPRPQSRPGGPPISRGATAVAVKEEWEEF
>Mature_536_residues
GTAMNQDYAIGERTAFMGIDDKARSALRDLRPVIRAEIGKALDNFYGKVRATPETRKFFSDDRHMNAASSRQQAHWGVIA
EGQFSDDYVQAVRAIGQTHARIGLEPRWYIGGYAVVGDHLVRAVIDSMWPRGLLAKGGSDRAGEAVAALMKAIFLDMDFA
ISIYLETLENERQRLEAEQKATRARQEHVVTLLAEALDRLAAGDLLARIDGEVCSEFEKLKADFNHAVELLDQAMCGVGG
ATEGIRSSTEEISVAADDLSRRTEQQAASLEQTAAALDEITATVRRSAAGAKQAQEVVAGAKTEAERSGSVVNQAVAAMG
EIETSSREIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSADAAKEIKALINTSTKQVEAGV
ALVGQTGDALRGIVSKVAEIDELIAQISVSAQEQSGGLHEVNTAVNQMDQVTQQNAAMVEQTTAATHSLKSQTGELVRQV
ETFRTSEGRRSSAAASPAPVQMAQPARSPRPQSRPGGPPISRGATAVAVKEEWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=345, Percent_Identity=44.0579710144928, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1788195, Length=311, Percent_Identity=43.4083601286174, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788194, Length=322, Percent_Identity=44.4099378881988, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1787690, Length=304, Percent_Identity=42.7631578947368, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=38.4615384615385, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57375; Mature: 57244

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTAMNQDYAIGERTAFMGIDDKARSALRDLRPVIRAEIGKALDNFYGKVRATPETRKFF
CCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SDDRHMNAASSRQQAHWGVIAEGQFSDDYVQAVRAIGQTHARIGLEPRWYIGGYAVVGDH
CCCCCCCHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHH
LVRAVIDSMWPRGLLAKGGSDRAGEAVAALMKAIFLDMDFAISIYLETLENERQRLEAEQ
HHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KATRARQEHVVTLLAEALDRLAAGDLLARIDGEVCSEFEKLKADFNHAVELLDQAMCGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GATEGIRSSTEEISVAADDLSRRTEQQAASLEQTAAALDEITATVRRSAAGAKQAQEVVA
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GAKTEAERSGSVVNQAVAAMGEIETSSREIGNIIGVIDEIAFQTNLLALNAGVEAARAGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCC
AGRGFAVVAQEVRALAQRSADAAKEIKALINTSTKQVEAGVALVGQTGDALRGIVSKVAE
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHCCCCEECCCCHHHHHHHHHHHH
IDELIAQISVSAQEQSGGLHEVNTAVNQMDQVTQQNAAMVEQTTAATHSLKSQTGELVRQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VETFRTSEGRRSSAAASPAPVQMAQPARSPRPQSRPGGPPISRGATAVAVKEEWEEF
HHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCC
>Mature Secondary Structure 
GTAMNQDYAIGERTAFMGIDDKARSALRDLRPVIRAEIGKALDNFYGKVRATPETRKFF
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SDDRHMNAASSRQQAHWGVIAEGQFSDDYVQAVRAIGQTHARIGLEPRWYIGGYAVVGDH
CCCCCCCHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHH
LVRAVIDSMWPRGLLAKGGSDRAGEAVAALMKAIFLDMDFAISIYLETLENERQRLEAEQ
HHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KATRARQEHVVTLLAEALDRLAAGDLLARIDGEVCSEFEKLKADFNHAVELLDQAMCGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GATEGIRSSTEEISVAADDLSRRTEQQAASLEQTAAALDEITATVRRSAAGAKQAQEVVA
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GAKTEAERSGSVVNQAVAAMGEIETSSREIGNIIGVIDEIAFQTNLLALNAGVEAARAGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCC
AGRGFAVVAQEVRALAQRSADAAKEIKALINTSTKQVEAGVALVGQTGDALRGIVSKVAE
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHCCCCEECCCCHHHHHHHHHHHH
IDELIAQISVSAQEQSGGLHEVNTAVNQMDQVTQQNAAMVEQTTAATHSLKSQTGELVRQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VETFRTSEGRRSSAAASPAPVQMAQPARSPRPQSRPGGPPISRGATAVAVKEEWEEF
HHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]