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The map label for this gene is mcpA

Identifier: 16124685

GI number: 16124685

Start: 445545

End: 447518

Strand: Direct

Name: mcpA

Synonym: CC_0430

Alternate gene names: 16124685

Gene position: 445545-447518 (Clockwise)

Preceding gene: 16124683

Following gene: 16124686

Centisome position: 11.09

GC content: 65.45

Gene sequence:

>1974_bases
ATGAAACGGATCCGGCTCGTCGATCTACCATTGATCATCAAGATCGGCTTTGCGCCGGCGTTCGCGCTTCTGATGCTGGC
CGTGATGGCCGGCGGCGCGATCCTTGTTCAGAAGAGCCAGTCGGCTGCGCTGAAGCAGGTCGTGGAACGCGACATGCGTC
AGAATTTGGAGATCCAGCGGATTTCCAAGCGCATCTCGAACATCAACGGCGAGTTGTTCGTCGTGATGACTCATAAGGCT
GGCAATATCGACGTCGACAAGAACGACGCGCGTATGGCCGCCGTTCTGGTCGAGACCGACGCGGTCAAGAAGGACCTGCT
GGCGCTGAAGAGCAAGCTGCCGGCCGAGGAACAGCCGAAGATCGCTGAACTGATCAAGTCGCTTGAAGAGTGCCGCAGCG
CTATCGACACGGTCAGCGGTATGATCAGCGTCGACTTCAACATGGCCGCAGGCTTCATCGCGCCGTTCGAAGAACAATAC
GTCAAGATGACGGGCCAGCTGGACCAGGTCGTCGCCGCCGCTAATCAGCGAATCGAGTCCGAGAGCGCCAAGCGTCAGGC
TCAGGCCACCGCCGCCATGAGCGTGACGATCATCATGTCGCTCCTGACCCTGGGTGCGGTCGGCGCTCTGGCGTTCCTGA
CGGTCATGACGACGCGCAAGTCCATCAACGACATCGCCGCCGCGACCGATAAGCTGTCGAAGGGCGACAACAGCATCGAT
CTTGAGAAGATGACGCGCGGTGACGAACTGGGCGGCATCGTTACGGCCCTGAAGGTCTTCCGCGACAACCAGGTGCACCT
TGAGCAACTGCGCGCCGATCAGGAAAAGTCCGCCGCCCTCACGGCTGATGAACGTCGGTCCAAGGAAGCCGCCGCCGCCG
CCGCCGCCCAGGAAGCCTCGCTGGTTGTTTCCAACCTGGCCGAGGGCCTTGAGAAGCTGGCCTCGGGCGACCTGACCTTC
CGCGTCACCGCCGACTTCCCGGGCGACTACCGCAAGCTGAAGGACGACTTCAACGCCGCCATGGGCTCGCTGCAGGAGAC
GATGAAGGTCATCGCCGCCTCGACCGACGGCCTAAGCACCGGCGCCGACGAGATCGCTCACGCTTCGGACGACCTGTCGC
GCCGTACCGAGCAACAGGCTGCGAGCCTGGAAGAAACCGCCGCCGCCCTCGACGAGCTGACCGCCACGGTGCGCCGCACC
GCCGCCGGCGCCCGTCAGGCCTCGGACGTCGTCTCCACCACCCGTGGCGAAGCGACGCATAGCGGTCAGGTCGTGCACCA
GGCAGTCTCGGCCATGGGCGAGATCGAGAAGAGCTCGGGCCAGATCAGCCAGATCATCGGGGTCATCGACGAAATCGCCT
TCCAGACCAACCTTCTGGCCCTGAACGCAGGCGTCGAAGCCGCCCGGGCGGGCGAGGCGGGCCGCGGCTTCGCGGTCGTC
GCTCAGGAAGTCCGGGCCCTGGCCCAGCGCTCGGCCGAGGCCGCCAAGGAGATCAAGGCTCTGATCTCCAGCTCGACCCA
GCAGGTCAGCCAAGGCGTGAGCCTGGTGGGTCAAACGGGCGAGGCGCTGCAGCGGATCGTGACGAAGGTCGGCGAGATCG
ACGCCCTGGTCACCGAGATCGCCGCGTCGGCCGCCGAACAGGCCACCGGCCTGAACGAAGTGAACACCGCTGTGAACCAG
ATGGACCAGGTCACCCAGCAGAACGCCGCCATGGTCGAGCAGTCGACCGCCGCGACGCACTCGCTGAAGGGCGAGACCGC
CGAGCTGGTCCGCCTGATGGCCCGCTTCCAGGTGGGCTCCGGTTCGTCGTCCTACGCCCGTCCGGCCGTCGCCGACGCGG
GTCATCACGCCCCCGCGCGAAATCCGGTGGCCGAGCAACAGGCCCGTCTGAACACCTTCGCCCGTCCGGGTCGGAGCAGC
GGTTCGGCGGCCCTCGCCCAGGCCCCCGCCTCGGATGGTTGGGAGGAATTCTAA

Upstream 100 bases:

>100_bases
TCCTTTAACCAAGTCAGAGTCTGTTAGGAATCTATCGGGATTATCACCCTTCATGTTGGCGATCCGTGGGCACGGAGCGC
TGGTTGGAGGGGACCTTGCG

Downstream 100 bases:

>100_bases
TGGTTGCCGCGATCTCGCTGCCCGAAAACCTGGATCTCAAGACCGCAGCCCCTCTGAAGGCGGCTTTCCTCGAGCGGCGC
GGCGCGGAGATCATCGTCGA

Product: methyl-accepting chemotaxis protein McpA

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MKRIRLVDLPLIIKIGFAPAFALLMLAVMAGGAILVQKSQSAALKQVVERDMRQNLEIQRISKRISNINGELFVVMTHKA
GNIDVDKNDARMAAVLVETDAVKKDLLALKSKLPAEEQPKIAELIKSLEECRSAIDTVSGMISVDFNMAAGFIAPFEEQY
VKMTGQLDQVVAAANQRIESESAKRQAQATAAMSVTIIMSLLTLGAVGALAFLTVMTTRKSINDIAAATDKLSKGDNSID
LEKMTRGDELGGIVTALKVFRDNQVHLEQLRADQEKSAALTADERRSKEAAAAAAAQEASLVVSNLAEGLEKLASGDLTF
RVTADFPGDYRKLKDDFNAAMGSLQETMKVIAASTDGLSTGADEIAHASDDLSRRTEQQAASLEETAAALDELTATVRRT
AAGARQASDVVSTTRGEATHSGQVVHQAVSAMGEIEKSSGQISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVV
AQEVRALAQRSAEAAKEIKALISSSTQQVSQGVSLVGQTGEALQRIVTKVGEIDALVTEIAASAAEQATGLNEVNTAVNQ
MDQVTQQNAAMVEQSTAATHSLKGETAELVRLMARFQVGSGSSSYARPAVADAGHHAPARNPVAEQQARLNTFARPGRSS
GSAALAQAPASDGWEEF

Sequences:

>Translated_657_residues
MKRIRLVDLPLIIKIGFAPAFALLMLAVMAGGAILVQKSQSAALKQVVERDMRQNLEIQRISKRISNINGELFVVMTHKA
GNIDVDKNDARMAAVLVETDAVKKDLLALKSKLPAEEQPKIAELIKSLEECRSAIDTVSGMISVDFNMAAGFIAPFEEQY
VKMTGQLDQVVAAANQRIESESAKRQAQATAAMSVTIIMSLLTLGAVGALAFLTVMTTRKSINDIAAATDKLSKGDNSID
LEKMTRGDELGGIVTALKVFRDNQVHLEQLRADQEKSAALTADERRSKEAAAAAAAQEASLVVSNLAEGLEKLASGDLTF
RVTADFPGDYRKLKDDFNAAMGSLQETMKVIAASTDGLSTGADEIAHASDDLSRRTEQQAASLEETAAALDELTATVRRT
AAGARQASDVVSTTRGEATHSGQVVHQAVSAMGEIEKSSGQISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVV
AQEVRALAQRSAEAAKEIKALISSSTQQVSQGVSLVGQTGEALQRIVTKVGEIDALVTEIAASAAEQATGLNEVNTAVNQ
MDQVTQQNAAMVEQSTAATHSLKGETAELVRLMARFQVGSGSSSYARPAVADAGHHAPARNPVAEQQARLNTFARPGRSS
GSAALAQAPASDGWEEF
>Mature_657_residues
MKRIRLVDLPLIIKIGFAPAFALLMLAVMAGGAILVQKSQSAALKQVVERDMRQNLEIQRISKRISNINGELFVVMTHKA
GNIDVDKNDARMAAVLVETDAVKKDLLALKSKLPAEEQPKIAELIKSLEECRSAIDTVSGMISVDFNMAAGFIAPFEEQY
VKMTGQLDQVVAAANQRIESESAKRQAQATAAMSVTIIMSLLTLGAVGALAFLTVMTTRKSINDIAAATDKLSKGDNSID
LEKMTRGDELGGIVTALKVFRDNQVHLEQLRADQEKSAALTADERRSKEAAAAAAAQEASLVVSNLAEGLEKLASGDLTF
RVTADFPGDYRKLKDDFNAAMGSLQETMKVIAASTDGLSTGADEIAHASDDLSRRTEQQAASLEETAAALDELTATVRRT
AAGARQASDVVSTTRGEATHSGQVVHQAVSAMGEIEKSSGQISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVV
AQEVRALAQRSAEAAKEIKALISSSTQQVSQGVSLVGQTGEALQRIVTKVGEIDALVTEIAASAAEQATGLNEVNTAVNQ
MDQVTQQNAAMVEQSTAATHSLKGETAELVRLMARFQVGSGSSSYARPAVADAGHHAPARNPVAEQQARLNTFARPGRSS
GSAALAQAPASDGWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI1788195, Length=331, Percent_Identity=44.1087613293051, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI2367378, Length=273, Percent_Identity=47.985347985348, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787690, Length=302, Percent_Identity=44.0397350993377, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1788194, Length=239, Percent_Identity=51.0460251046025, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=36.8200836820084, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MCPA_CAUCR (Q00986)

Other databases:

- EMBL:   X66502
- EMBL:   AE005673
- PIR:   S23064
- RefSeq:   NP_419249.1
- ProteinModelPortal:   Q00986
- SMR:   Q00986
- GeneID:   942024
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_0430
- NMPDR:   fig|190650.1.peg.429
- TIGR:   CC_0430
- HOGENOM:   HBG752668
- OMA:   ESESAKR
- ProtClustDB:   CLSK2301612
- GO:   GO:0006935
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- PRINTS:   PR00260
- SMART:   SM00304
- SMART:   SM00283

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal

EC number: NA

Molecular weight: Translated: 69346; Mature: 69346

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc4c633c)-; HASH(0xc5a8ef4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIRLVDLPLIIKIGFAPAFALLMLAVMAGGAILVQKSQSAALKQVVERDMRQNLEIQR
CCCCEEECCCHHEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCHHHH
ISKRISNINGELFVVMTHKAGNIDVDKNDARMAAVLVETDAVKKDLLALKSKLPAEEQPK
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCH
IAELIKSLEECRSAIDTVSGMISVDFNMAAGFIAPFEEQYVKMTGQLDQVVAAANQRIES
HHHHHHHHHHHHHHHHHHHHHHEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ESAKRQAQATAAMSVTIIMSLLTLGAVGALAFLTVMTTRKSINDIAAATDKLSKGDNSID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LEKMTRGDELGGIVTALKVFRDNQVHLEQLRADQEKSAALTADERRSKEAAAAAAAQEAS
HHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVVSNLAEGLEKLASGDLTFRVTADFPGDYRKLKDDFNAAMGSLQETMKVIAASTDGLST
HHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GADEIAHASDDLSRRTEQQAASLEETAAALDELTATVRRTAAGARQASDVVSTTRGEATH
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGQVVHQAVSAMGEIEKSSGQISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVV
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHH
AQEVRALAQRSAEAAKEIKALISSSTQQVSQGVSLVGQTGEALQRIVTKVGEIDALVTEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AASAAEQATGLNEVNTAVNQMDQVTQQNAAMVEQSTAATHSLKGETAELVRLMARFQVGS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GSSSYARPAVADAGHHAPARNPVAEQQARLNTFARPGRSSGSAALAQAPASDGWEEF
CCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCH
>Mature Secondary Structure
MKRIRLVDLPLIIKIGFAPAFALLMLAVMAGGAILVQKSQSAALKQVVERDMRQNLEIQR
CCCCEEECCCHHEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCHHHH
ISKRISNINGELFVVMTHKAGNIDVDKNDARMAAVLVETDAVKKDLLALKSKLPAEEQPK
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCH
IAELIKSLEECRSAIDTVSGMISVDFNMAAGFIAPFEEQYVKMTGQLDQVVAAANQRIES
HHHHHHHHHHHHHHHHHHHHHHEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ESAKRQAQATAAMSVTIIMSLLTLGAVGALAFLTVMTTRKSINDIAAATDKLSKGDNSID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LEKMTRGDELGGIVTALKVFRDNQVHLEQLRADQEKSAALTADERRSKEAAAAAAAQEAS
HHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVVSNLAEGLEKLASGDLTFRVTADFPGDYRKLKDDFNAAMGSLQETMKVIAASTDGLST
HHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GADEIAHASDDLSRRTEQQAASLEETAAALDELTATVRRTAAGARQASDVVSTTRGEATH
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGQVVHQAVSAMGEIEKSSGQISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVV
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHH
AQEVRALAQRSAEAAKEIKALISSSTQQVSQGVSLVGQTGEALQRIVTKVGEIDALVTEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AASAAEQATGLNEVNTAVNQMDQVTQQNAAMVEQSTAATHSLKGETAELVRLMARFQVGS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GSSSYARPAVADAGHHAPARNPVAEQQARLNTFARPGRSSGSAALAQAPASDGWEEF
CCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647