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The map label for this gene is trh_2

Identifier: 16120323

GI number: 16120323

Start: 341585

End: 341866

Strand: Reverse

Name: trh_2

Synonym: VNG6451G

Alternate gene names: 16120323

Gene position: 341866-341585 (Counterclockwise)

Preceding gene: 16120324

Following gene: 16120320

Centisome position: 93.55

GC content: 67.73

Gene sequence:

>282_bases
GTGTTCTACGCGGTGGGCCACACGCCGAACACGCGGTTCCTGGATGAGACTGCCGTCGAACGAGACGAAAGCGGCTACAT
CTTCACGCAGGCAGACGATGTCGGCCGACCGACGGCCCGGACGAGCGTCGATGGCGTGTTCGCCGCCGGCGACGTCGCCG
ACCCCCGGTACCGCCAGGCGATCACGTCCGCCGGCACCGGGAGTATGGCTGCCCTCGATGCCGAGGAGTTCCTCGAGACG
CTGCGCGAATCAGACGAGCTGACGGCGACTGCGACCGCCTAA

Upstream 100 bases:

>100_bases
CGTCACCGGTGCCACGCTCGTCTCCCACCCCGATGGCTACCCCACGGAGAAGGCCGAGTCCGGGGTCGACGTCGAGCGGG
AGACCGTCGATGTTGGCGGC

Downstream 100 bases:

>100_bases
CTGTTCACCCTTCTCAGGAGGCGGTGTTCAGATAAGGATTGAAAGGTGAGGCGGAGCGTTTTCTGAGTGATCTATGCCCG
AAAACGCTCGCCTCGACGAG

Product: thioredoxin reductase-like protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 93; Mature: 93

Protein sequence:

>93_residues
MFYAVGHTPNTRFLDETAVERDESGYIFTQADDVGRPTARTSVDGVFAAGDVADPRYRQAITSAGTGSMAALDAEEFLET
LRESDELTATATA

Sequences:

>Translated_93_residues
MFYAVGHTPNTRFLDETAVERDESGYIFTQADDVGRPTARTSVDGVFAAGDVADPRYRQAITSAGTGSMAALDAEEFLET
LRESDELTATATA
>Mature_93_residues
MFYAVGHTPNTRFLDETAVERDESGYIFTQADDVGRPTARTSVDGVFAAGDVADPRYRQAITSAGTGSMAALDAEEFLET
LRESDELTATATA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=81, Percent_Identity=58.0246913580247, Blast_Score=82, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320560, Length=81, Percent_Identity=55.5555555555556, Blast_Score=85, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321898, Length=78, Percent_Identity=52.5641025641026, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 9968; Mature: 9968

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYAVGHTPNTRFLDETAVERDESGYIFTQADDVGRPTARTSVDGVFAAGDVADPRYRQA
CEEECCCCCCCCCCCCHHCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHH
ITSAGTGSMAALDAEEFLETLRESDELTATATA
HHCCCCCCEEEECHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MFYAVGHTPNTRFLDETAVERDESGYIFTQADDVGRPTARTSVDGVFAAGDVADPRYRQA
CEEECCCCCCCCCCCCHHCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHH
ITSAGTGSMAALDAEEFLETLRESDELTATATA
HHCCCCCCEEEECHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]