Click here to switch to the map view.

The map label for this gene is trxB1_2

Identifier: 16120324

GI number: 16120324

Start: 341993

End: 342610

Strand: Reverse

Name: trxB1_2

Synonym: VNG6452G

Alternate gene names: 16120324

Gene position: 342610-341993 (Counterclockwise)

Preceding gene: 16120325

Following gene: 16120323

Centisome position: 93.76

GC content: 68.77

Gene sequence:

>618_bases
ATGACTGAGGACAGCCACGACCTAGTCATCGCCGGGTCGGGAATCGCCGGCCTCTCGGCAGCGGTCTACGCAGCGCGTGC
CGACCTCGAACCCCTCGTCTTGGAGGGCGACGAGCCGGGCGGCCAGCTCACGCTGACGACCGACGTCGAGAACTACCTCG
GCTTCCCCGACGGCGTCGGCGGCATGGACCTCGTCCAACGCGGCAAAGAGCAGGCCGAGCAGTTCGGCGCCCAGTTCGAA
CACGGCCGCATCGAGGCTGCGGACCTGGACGGCCAGCCGCTGGAGCTATCGCTGTCGACCGGCGACACGCTCTACACGCG
GTCGCTGATCGTCGCCACCGGCGCGAGCGCGCGCTGGGTCGGTGCCGAGAACGAAGACGAGCTGATGGGGGCCGGGCTCT
CGACGTGTGCGACCTGTGACGGCGCGTTCCACCGCGGCGACGATGTCCTCGTCGTCGGCGGCGGCGACAGCGCCATGGAG
GAAGCGTTGTTCCTCGCGAAGTTCGCCGACTCTGTGACGGTCGTCCACCGACGTGAGGAGCTGCGTGCGTCCGAGATCAT
GGCCGACCGCGCTCGCGACCACGACGACGTCCAGTTCCGCTGGAACACGGAGCTCTAA

Upstream 100 bases:

>100_bases
CACGCTCGTTCTCTTCGCGGACGGCGAGCAAGTCGAGGAAGTCGTCGGCCTTCAGGATGAAGACGCGCTCAAGGACCTCA
TCGAGAGCTACACCGAGTAA

Downstream 100 bases:

>100_bases
GCCATCCACGGCTCCCAGGAGACGGGCGTCACCGGTGCCACGCTCGTCTCCCACCCCGATGGCTACCCCACGGAGAAGGC
CGAGTCCGGGGTCGACGTCG

Product: thioredoxin reductase

Products: NA

Alternate protein names: Thioredoxin reductase; TRXR; Thioredoxin [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTEDSHDLVIAGSGIAGLSAAVYAARADLEPLVLEGDEPGGQLTLTTDVENYLGFPDGVGGMDLVQRGKEQAEQFGAQFE
HGRIEAADLDGQPLELSLSTGDTLYTRSLIVATGASARWVGAENEDELMGAGLSTCATCDGAFHRGDDVLVVGGGDSAME
EALFLAKFADSVTVVHRREELRASEIMADRARDHDDVQFRWNTEL

Sequences:

>Translated_205_residues
MTEDSHDLVIAGSGIAGLSAAVYAARADLEPLVLEGDEPGGQLTLTTDVENYLGFPDGVGGMDLVQRGKEQAEQFGAQFE
HGRIEAADLDGQPLELSLSTGDTLYTRSLIVATGASARWVGAENEDELMGAGLSTCATCDGAFHRGDDVLVVGGGDSAME
EALFLAKFADSVTVVHRREELRASEIMADRARDHDDVQFRWNTEL
>Mature_204_residues
TEDSHDLVIAGSGIAGLSAAVYAARADLEPLVLEGDEPGGQLTLTTDVENYLGFPDGVGGMDLVQRGKEQAEQFGAQFEH
GRIEAADLDGQPLELSLSTGDTLYTRSLIVATGASARWVGAENEDELMGAGLSTCATCDGAFHRGDDVLVVGGGDSAMEE
ALFLAKFADSVTVVHRREELRASEIMADRARDHDDVQFRWNTEL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=193, Percent_Identity=46.1139896373057, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87081763, Length=205, Percent_Identity=33.1707317073171, Blast_Score=95, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320560, Length=208, Percent_Identity=39.4230769230769, Blast_Score=153, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321898, Length=208, Percent_Identity=38.4615384615385, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF00085 Thioredoxin [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 21831; Mature: 21700

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDSHDLVIAGSGIAGLSAAVYAARADLEPLVLEGDEPGGQLTLTTDVENYLGFPDGVG
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECHHHHCCCCCCCC
GMDLVQRGKEQAEQFGAQFEHGRIEAADLDGQPLELSLSTGDTLYTRSLIVATGASARWV
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCEEEEEEEEEEECCCEEEE
GAENEDELMGAGLSTCATCDGAFHRGDDVLVVGGGDSAMEEALFLAKFADSVTVVHRREE
CCCCCHHHHCCCCHHHHHCCCCEECCCCEEEECCCCHHHHHHHHHHHHHCHHHEEHHHHH
LRASEIMADRARDHDDVQFRWNTEL
HHHHHHHHHHCCCCCCEEEEECCCC
>Mature Secondary Structure 
TEDSHDLVIAGSGIAGLSAAVYAARADLEPLVLEGDEPGGQLTLTTDVENYLGFPDGVG
CCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECHHHHCCCCCCCC
GMDLVQRGKEQAEQFGAQFEHGRIEAADLDGQPLELSLSTGDTLYTRSLIVATGASARWV
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCEEEEEEEEEEECCCEEEE
GAENEDELMGAGLSTCATCDGAFHRGDDVLVVGGGDSAMEEALFLAKFADSVTVVHRREE
CCCCCHHHHCCCCHHHHHCCCCEECCCCEEEECCCCHHHHHHHHHHHHHCHHHEEHHHHH
LRASEIMADRARDHDDVQFRWNTEL
HHHHHHHHHHCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969512; 7476189; 11234002 [H]