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The map label for this gene is nhaC3

Identifier: 16120222

GI number: 16120222

Start: 242960

End: 244417

Strand: Reverse

Name: nhaC3

Synonym: VNG6313G

Alternate gene names: 16120222

Gene position: 244417-242960 (Counterclockwise)

Preceding gene: 16120223

Following gene: 16120218

Centisome position: 66.89

GC content: 58.64

Gene sequence:

>1458_bases
ATGGTAGAATTCGAACCGAGAAGTTACGAGGACTTTGATCCGGAGAAACGACCGTCGTTCGGACAAGCGCTCCTCCCGAT
CGCTGGGATGATTACGTTCCTGGCCGTCGGTATCGTTCTTTTGGGCCTTGACGCCCAAATGCCCCTGCTTTGGGGGATCG
CCTTCACTGGTGTGATCGCACGATACGGCTGGGGATACACGTGGGACGAACTCTTCGACGGGATTTCAAACAGCATTGTC
ATGGGATTGGGGGCGATATTTATCCTGTTTATTATCTACATGCTGATCGCGTCCTGGGTTGATGCTGGGACGATCCCGTT
CATCATGTACTGGGGGCTGGAGTTCCTCACACCGGCGGTCTTCGTTCCGTTGGCAGCGCTCCTTTCGTTCGTGGTTGCGA
CGGCAATCGGTTCCTCATGGACGACAGCCGGCTCGCTCGGTATCGCGCTGGTCGGCATTGGCTCCGGACTCGGGATCCCA
GCGCCGCTGACTGCGGGTGCGATCCTCTCCGGCGTGTACATGGGCGACAAGCAGTCGCCGCTTTCCGACACTACACTGCT
CGCCTCGGGTGTCAGTGACGTTGACCTCTGGGATCACGTGCGCGGGATGTTCCCGAACACTATCATCGTTGGGGTTATCT
CTCTTGCACTCTACGCCGTCCTCGGGTTGATGGCAGAGACCGGTGGCACTGGTGGTACAGGCGCGGAAGTCGCACAGATC
CAGGGCGGTCTGGCAGGCACATACACGCTTTCTGTCCTGGTGTTGCTCCCGCTGGTCATTACCTTCGGGTTGGCGATCAA
GGGGTACCCCGCGCTGCCGTCGCTCGGTGCCGGCGTGTTCTCCGCGGCAGGCGTCTCGATCCTCATCCAGGGTCGTGGGT
TCGCTGAGGCATGGCAGATCATCTATAGCGGAACAGGACCGAAGACGGGTGTCGACCTCGTTAACAACCTCCTCAGTACC
GGTGGGCTTGAAGGGTCGATCTGGGTTATTACCATTGTCTTCGGTGCCCTCTCGATCGGAGGTATACTTGAGGCGACAGG
CGTATTGTCGGTTATAGCGCACAACACTGCAAAAGCTGTCGATAGTGTCGGAGGGGCAACTCTTGTCACCGCGCTCGGCC
CGCTCGTGATCAACGCACTCACTGCGGACCAGTACATGTCCATCGTTATCCCTGGCATGACGTTCCGCGACCTCAACGAC
GAGTACGATCTCGACGGAACGAGCCTGTCCCGGACCCTCGAAGAGACTGGGACTGTCTCGGAGCCGATGATTCCGTGGAA
CTCCGGTGGCGTGTTCATGGCCAGTGCGCTCGGGGTGCCCGTGTTGAGTTATCTGCCGTACTACTTCGTGGGGATTCTCT
CGCCCATCCTGGTTGTTATCATGGGTTTCACCGGCTGGAAGATGTACATGAAAGACCCCGAGGAGTCACCCGAAGAGTCG
GCCGATACGGCCGCATAA

Upstream 100 bases:

>100_bases
GGAATAACGCCAACACGTAGGAGAATAAGAGATGCTCCTGACGCCACAAACGGCAGCTGATGGATCGCCAACTAAAATGA
AAACAAACAAATAATTACCA

Downstream 100 bases:

>100_bases
CGTCGGCGTCTCGGATCCGGTCTTCGAGCCGTCTTTTTTACTAGTCCGTACGGAAGACACCGGCGCTCCTGTGTCGTTCT
TACAGCGATCGTAGTAGCTG

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MVEFEPRSYEDFDPEKRPSFGQALLPIAGMITFLAVGIVLLGLDAQMPLLWGIAFTGVIARYGWGYTWDELFDGISNSIV
MGLGAIFILFIIYMLIASWVDAGTIPFIMYWGLEFLTPAVFVPLAALLSFVVATAIGSSWTTAGSLGIALVGIGSGLGIP
APLTAGAILSGVYMGDKQSPLSDTTLLASGVSDVDLWDHVRGMFPNTIIVGVISLALYAVLGLMAETGGTGGTGAEVAQI
QGGLAGTYTLSVLVLLPLVITFGLAIKGYPALPSLGAGVFSAAGVSILIQGRGFAEAWQIIYSGTGPKTGVDLVNNLLST
GGLEGSIWVITIVFGALSIGGILEATGVLSVIAHNTAKAVDSVGGATLVTALGPLVINALTADQYMSIVIPGMTFRDLND
EYDLDGTSLSRTLEETGTVSEPMIPWNSGGVFMASALGVPVLSYLPYYFVGILSPILVVIMGFTGWKMYMKDPEESPEES
ADTAA

Sequences:

>Translated_485_residues
MVEFEPRSYEDFDPEKRPSFGQALLPIAGMITFLAVGIVLLGLDAQMPLLWGIAFTGVIARYGWGYTWDELFDGISNSIV
MGLGAIFILFIIYMLIASWVDAGTIPFIMYWGLEFLTPAVFVPLAALLSFVVATAIGSSWTTAGSLGIALVGIGSGLGIP
APLTAGAILSGVYMGDKQSPLSDTTLLASGVSDVDLWDHVRGMFPNTIIVGVISLALYAVLGLMAETGGTGGTGAEVAQI
QGGLAGTYTLSVLVLLPLVITFGLAIKGYPALPSLGAGVFSAAGVSILIQGRGFAEAWQIIYSGTGPKTGVDLVNNLLST
GGLEGSIWVITIVFGALSIGGILEATGVLSVIAHNTAKAVDSVGGATLVTALGPLVINALTADQYMSIVIPGMTFRDLND
EYDLDGTSLSRTLEETGTVSEPMIPWNSGGVFMASALGVPVLSYLPYYFVGILSPILVVIMGFTGWKMYMKDPEESPEES
ADTAA
>Mature_485_residues
MVEFEPRSYEDFDPEKRPSFGQALLPIAGMITFLAVGIVLLGLDAQMPLLWGIAFTGVIARYGWGYTWDELFDGISNSIV
MGLGAIFILFIIYMLIASWVDAGTIPFIMYWGLEFLTPAVFVPLAALLSFVVATAIGSSWTTAGSLGIALVGIGSGLGIP
APLTAGAILSGVYMGDKQSPLSDTTLLASGVSDVDLWDHVRGMFPNTIIVGVISLALYAVLGLMAETGGTGGTGAEVAQI
QGGLAGTYTLSVLVLLPLVITFGLAIKGYPALPSLGAGVFSAAGVSILIQGRGFAEAWQIIYSGTGPKTGVDLVNNLLST
GGLEGSIWVITIVFGALSIGGILEATGVLSVIAHNTAKAVDSVGGATLVTALGPLVINALTADQYMSIVIPGMTFRDLND
EYDLDGTSLSRTLEETGTVSEPMIPWNSGGVFMASALGVPVLSYLPYYFVGILSPILVVIMGFTGWKMYMKDPEESPEES
ADTAA

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 50523; Mature: 50523

Theoretical pI: Translated: 3.85; Mature: 3.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEFEPRSYEDFDPEKRPSFGQALLPIAGMITFLAVGIVLLGLDAQMPLLWGIAFTGVIA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RYGWGYTWDELFDGISNSIVMGLGAIFILFIIYMLIASWVDAGTIPFIMYWGLEFLTPAV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FVPLAALLSFVVATAIGSSWTTAGSLGIALVGIGSGLGIPAPLTAGAILSGVYMGDKQSP
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCC
LSDTTLLASGVSDVDLWDHVRGMFPNTIIVGVISLALYAVLGLMAETGGTGGTGAEVAQI
CCHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
QGGLAGTYTLSVLVLLPLVITFGLAIKGYPALPSLGAGVFSAAGVSILIQGRGFAEAWQI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEEEEECCCHHHHHHH
IYSGTGPKTGVDLVNNLLSTGGLEGSIWVITIVFGALSIGGILEATGVLSVIAHNTAKAV
HHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSVGGATLVTALGPLVINALTADQYMSIVIPGMTFRDLNDEYDLDGTSLSRTLEETGTVS
HHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCEEECCCCCCCCCCHHHHHHHHHCCCCC
EPMIPWNSGGVFMASALGVPVLSYLPYYFVGILSPILVVIMGFTGWKMYMKDPEESPEES
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
ADTAA
CCCCC
>Mature Secondary Structure
MVEFEPRSYEDFDPEKRPSFGQALLPIAGMITFLAVGIVLLGLDAQMPLLWGIAFTGVIA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RYGWGYTWDELFDGISNSIVMGLGAIFILFIIYMLIASWVDAGTIPFIMYWGLEFLTPAV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FVPLAALLSFVVATAIGSSWTTAGSLGIALVGIGSGLGIPAPLTAGAILSGVYMGDKQSP
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCC
LSDTTLLASGVSDVDLWDHVRGMFPNTIIVGVISLALYAVLGLMAETGGTGGTGAEVAQI
CCHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
QGGLAGTYTLSVLVLLPLVITFGLAIKGYPALPSLGAGVFSAAGVSILIQGRGFAEAWQI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEEEEECCCHHHHHHH
IYSGTGPKTGVDLVNNLLSTGGLEGSIWVITIVFGALSIGGILEATGVLSVIAHNTAKAV
HHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSVGGATLVTALGPLVINALTADQYMSIVIPGMTFRDLNDEYDLDGTSLSRTLEETGTVS
HHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCEEECCCCCCCCCCHHHHHHHHHCCCCC
EPMIPWNSGGVFMASALGVPVLSYLPYYFVGILSPILVVIMGFTGWKMYMKDPEESPEES
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
ADTAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]