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The map label for this gene is exsB

Identifier: 16120215

GI number: 16120215

Start: 235629

End: 236318

Strand: Reverse

Name: exsB

Synonym: VNG6303G

Alternate gene names: 16120215

Gene position: 236318-235629 (Counterclockwise)

Preceding gene: 16120216

Following gene: 16120213

Centisome position: 64.67

GC content: 65.94

Gene sequence:

>690_bases
ATGAGCGCGAAGCGCGCTGTCGTGCTTGCATCCGGCGGGATGGACAGCGCCACCGCCGCTGCGGTTGCGCACAACGCCGG
CTACGAGGTGTACATGCTCCACACCTCGTACGGCCAGCAGACCGAGCACAAAGAACACGAGTGCGCAACGGCCCAAGCAG
CGGCCCTCGGTGCCGCGGACTTCCTCCATTTGACCACGGATCACCTCTCGAAGATCGGCGCGTCGAGCCTCACTGACGAC
GAGATGGCGGTCGCGGACGCCGACATGGAGAGCGACGAAATCCCCACCTCCTACGTGCCGTTCCGGAACGCCAACCTGCT
GGCGATGGCGACGTCGTACGCCGAGGCCAACGACTGTGAGGCGGTGTTCATCGGCGCGCACAGCGAGGACTTCTCGGGGT
ATCCGGACTGCCAGCCCGCGTTCTTCGAGGCGTTCCAGCAGACCGTCGCTGCCGGCACCAAACCCGACACCGAAATCAGC
ATCAACGCACCGTTCGTCGACTGGTCGAAGACCGACATCGCCGAGCGCGGCCTGGAACTCGGTGTCCCCTACGAGCACAC
GTGGAGTTGCTACCGCGCCGAGGCCCCCGCGTGTGGGACGTGCGACGCGTGTGCGTTCCGCCTCCAGGCGTTCCAGAACC
TGGGCGAACGCGACCCGATCGAATACGCCGAGCGCCCGTCGTACACGTAA

Upstream 100 bases:

>100_bases
CTGACGATACGATCGACACGAACGCACGCGCTCGGCGCGACCGCACAGCGACGACCAACCGCAGAACGGCCGCGGGTGCC
ACGCACCCGAGTGGTGGACG

Downstream 100 bases:

>100_bases
TGGCGGCCGTTCGCGCGCCCCGGTGGAAACGGCGAGCGCCGGTGACCGCTCCGGTCAGGAGTCGGGAGTCACCGTCAGCG
ACGTGATCCGTGCGCCGTCG

Product: succinoglycan biosynthesis

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSAKRAVVLASGGMDSATAAAVAHNAGYEVYMLHTSYGQQTEHKEHECATAQAAALGAADFLHLTTDHLSKIGASSLTDD
EMAVADADMESDEIPTSYVPFRNANLLAMATSYAEANDCEAVFIGAHSEDFSGYPDCQPAFFEAFQQTVAAGTKPDTEIS
INAPFVDWSKTDIAERGLELGVPYEHTWSCYRAEAPACGTCDACAFRLQAFQNLGERDPIEYAERPSYT

Sequences:

>Translated_229_residues
MSAKRAVVLASGGMDSATAAAVAHNAGYEVYMLHTSYGQQTEHKEHECATAQAAALGAADFLHLTTDHLSKIGASSLTDD
EMAVADADMESDEIPTSYVPFRNANLLAMATSYAEANDCEAVFIGAHSEDFSGYPDCQPAFFEAFQQTVAAGTKPDTEIS
INAPFVDWSKTDIAERGLELGVPYEHTWSCYRAEAPACGTCDACAFRLQAFQNLGERDPIEYAERPSYT
>Mature_228_residues
SAKRAVVLASGGMDSATAAAVAHNAGYEVYMLHTSYGQQTEHKEHECATAQAAALGAADFLHLTTDHLSKIGASSLTDDE
MAVADADMESDEIPTSYVPFRNANLLAMATSYAEANDCEAVFIGAHSEDFSGYPDCQPAFFEAFQQTVAAGTKPDTEISI
NAPFVDWSKTDIAERGLELGVPYEHTWSCYRAEAPACGTCDACAFRLQAFQNLGERDPIEYAERPSYT

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=206, Percent_Identity=35.9223300970874, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_HALSA (Q9HHN8)

Other databases:

- EMBL:   AE004438
- RefSeq:   NP_395803.1
- ProteinModelPortal:   Q9HHN8
- SMR:   Q9HHN8
- GeneID:   1449186
- GenomeReviews:   AE004438_GR
- KEGG:   hal:VNG6303G
- NMPDR:   fig|64091.1.peg.2487
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK537269
- BioCyc:   HSP64091:VNG6303G-MONOMER
- HAMAP:   MF_01633_A
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24660; Mature: 24529

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKRAVVLASGGMDSATAAAVAHNAGYEVYMLHTSYGQQTEHKEHECATAQAAALGAAD
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
FLHLTTDHLSKIGASSLTDDEMAVADADMESDEIPTSYVPFRNANLLAMATSYAEANDCE
HHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
AVFIGAHSEDFSGYPDCQPAFFEAFQQTVAAGTKPDTEISINAPFVDWSKTDIAERGLEL
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCCC
GVPYEHTWSCYRAEAPACGTCDACAFRLQAFQNLGERDPIEYAERPSYT
CCCCHHCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAKRAVVLASGGMDSATAAAVAHNAGYEVYMLHTSYGQQTEHKEHECATAQAAALGAAD
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
FLHLTTDHLSKIGASSLTDDEMAVADADMESDEIPTSYVPFRNANLLAMATSYAEANDCE
HHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
AVFIGAHSEDFSGYPDCQPAFFEAFQQTVAAGTKPDTEISINAPFVDWSKTDIAERGLEL
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCCC
GVPYEHTWSCYRAEAPACGTCDACAFRLQAFQNLGERDPIEYAERPSYT
CCCCHHCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11016950