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Identifier: 16120211

GI number: 16120211

Start: 230000

End: 231550

Strand: Direct

Name: Not Available

Synonym: VNG6298C

Alternate gene names: 16120211

Gene position: 230000-231550 (Clockwise)

Preceding gene: 16120210

Following gene: 16120214

Centisome position: 62.94

GC content: 65.38

Gene sequence:

>1551_bases
ATGGTAACACAACAGTCACGTCGAGAGGCGGTCGCGTGCGTCGAGTCCGGTGACACGGTTGGGATCGGGGGGTTCGTGGC
GACTGGCATCCCGGAAGCAGTCCTTGCTGCGCTGGGCGACCGCTATGAGCGAACGCGGGCTCCGCAGGATCTCACACTCT
ACCAGCCCGCGGCAGAGGGCGACCGGCAAGGACATGGCGTCTCACATCTCGTGCAGGAGGGCATGCTCGAACGGACGATC
GCCAGTCACTGGGGGTTCACACCGGACCTGATGGCGGCAGTCGTTAACAACGAAATCGAGGCGTACAACCTCCCGTTTGG
CGTCCTAGATCACTTGCTCCGGGACACCGCGGCTGGCAAGCCTGGAACGATCACGCATGTCGGACTGGACACGTTCGTTG
ACCCACGACGTGATGGTGGCAAAGCCAACGCCGTCACGAGCGAGGACCTCGTCGAGCGCGTCACACTCAACGGCACTGAG
TACCTGTTCTATCACGCGGTTCCGATCGACGTCGCGGTCATTCGCGGCACCACGGCCGACGAGCACGGGAACGTCACCAT
GGAGCGGGAGGCACTCGCCTCGAACATGCTGGCGCTGGCCCAAGCCGCACACAACACCGGCGGCAGGGTGATCGCGCAGG
TCGAGCGCGTCACGAGCGCGGGGACACTCGCGCCCCACGATGTCGCTGTACCCGGTGTGGTCGTTGATTCCGTCGTCGAG
GCATCGCCGGAAGACCACCCACAAACGTACGGCTCGGCCTACGACCCCGCACACAGCGGCACAGTCAAGCCACCGACGCC
CAGTACGGATCCGCTCCCGATCGACGAACGAACGATCATCGCACGCCGCGCCGCAATGGAACTCGACGCGGGCGCGGTCA
TCAACCTGGGCGTGGGGATCCCCGAACTCGTCTCAACGGCCGCCGCTGAGGGAGGTGTCGGCGACGCGATCACGGAAACC
GTGGAGTCCGGACCGGTTGGTGGGGCTGCGTCCGGCGGAATCGAGTTCGGAACGGCAGTCAACCACGATGCCCTCGTGTC
CTCACCCCAGCAGTTCGACTTCTACGACGGCGGCGGACTCGATGTCGGGTTCTTGGGGATGGCGCAGGTCGACGCGCAGG
GAAACGTCAACGTCAGCCGGTTCGGCTCCCAGTTCCCGGGCTGTGGCGGGTTCATCAACATCACGCAGAACGCCGCTGCA
GTCGTGTTCTGTGGCACGCTCACGACGGGCGGTCTCTCGGTCGCGGTCGCCGACGGAACAATCACGGTGACATCCGAGGG
GGCGCACTCGAAGTTCGTCGAGGACGTCGAACACGTCACATTCAGCGCTGATCACGCGCTGGAAACCGACCAGTCGGTTG
TGTACGTCACCGAGCGCGCCGTCTTCGAGTTGACGCCTGACGGCCTCACACTCACGGAGGTCGCACCCGGCATCGACCCC
GGAGCCGTGATCGCACAGCTCGGGTTCGACCCCGCTGTTGCGGACCCACTGGGCGTGATGCCGGCGCGGCTGTTCGCCGA
CGCGCCGCCGGATCTCACCGATGTCGTGTGA

Upstream 100 bases:

>100_bases
GCACCCCCAGTTTTCACTGTCACAGCGATCCTGCTCTCTCGGTGGCTCTATTCACGGAGCCAACACCAAGACAAAACTAT
CTGGCCTTGCACGGGGCTGT

Downstream 100 bases:

>100_bases
TCGCACGGCGGCCGCAGCTCACGGCGAACGAGCGGCGGCGTCCCGCTGAAGCGCACTGAACACTGTCCAGGCGGGATCGC
TCCCCGGGTGCACGACCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MVTQQSRREAVACVESGDTVGIGGFVATGIPEAVLAALGDRYERTRAPQDLTLYQPAAEGDRQGHGVSHLVQEGMLERTI
ASHWGFTPDLMAAVVNNEIEAYNLPFGVLDHLLRDTAAGKPGTITHVGLDTFVDPRRDGGKANAVTSEDLVERVTLNGTE
YLFYHAVPIDVAVIRGTTADEHGNVTMEREALASNMLALAQAAHNTGGRVIAQVERVTSAGTLAPHDVAVPGVVVDSVVE
ASPEDHPQTYGSAYDPAHSGTVKPPTPSTDPLPIDERTIIARRAAMELDAGAVINLGVGIPELVSTAAAEGGVGDAITET
VESGPVGGAASGGIEFGTAVNHDALVSSPQQFDFYDGGGLDVGFLGMAQVDAQGNVNVSRFGSQFPGCGGFINITQNAAA
VVFCGTLTTGGLSVAVADGTITVTSEGAHSKFVEDVEHVTFSADHALETDQSVVYVTERAVFELTPDGLTLTEVAPGIDP
GAVIAQLGFDPAVADPLGVMPARLFADAPPDLTDVV

Sequences:

>Translated_516_residues
MVTQQSRREAVACVESGDTVGIGGFVATGIPEAVLAALGDRYERTRAPQDLTLYQPAAEGDRQGHGVSHLVQEGMLERTI
ASHWGFTPDLMAAVVNNEIEAYNLPFGVLDHLLRDTAAGKPGTITHVGLDTFVDPRRDGGKANAVTSEDLVERVTLNGTE
YLFYHAVPIDVAVIRGTTADEHGNVTMEREALASNMLALAQAAHNTGGRVIAQVERVTSAGTLAPHDVAVPGVVVDSVVE
ASPEDHPQTYGSAYDPAHSGTVKPPTPSTDPLPIDERTIIARRAAMELDAGAVINLGVGIPELVSTAAAEGGVGDAITET
VESGPVGGAASGGIEFGTAVNHDALVSSPQQFDFYDGGGLDVGFLGMAQVDAQGNVNVSRFGSQFPGCGGFINITQNAAA
VVFCGTLTTGGLSVAVADGTITVTSEGAHSKFVEDVEHVTFSADHALETDQSVVYVTERAVFELTPDGLTLTEVAPGIDP
GAVIAQLGFDPAVADPLGVMPARLFADAPPDLTDVV
>Mature_516_residues
MVTQQSRREAVACVESGDTVGIGGFVATGIPEAVLAALGDRYERTRAPQDLTLYQPAAEGDRQGHGVSHLVQEGMLERTI
ASHWGFTPDLMAAVVNNEIEAYNLPFGVLDHLLRDTAAGKPGTITHVGLDTFVDPRRDGGKANAVTSEDLVERVTLNGTE
YLFYHAVPIDVAVIRGTTADEHGNVTMEREALASNMLALAQAAHNTGGRVIAQVERVTSAGTLAPHDVAVPGVVVDSVVE
ASPEDHPQTYGSAYDPAHSGTVKPPTPSTDPLPIDERTIIARRAAMELDAGAVINLGVGIPELVSTAAAEGGVGDAITET
VESGPVGGAASGGIEFGTAVNHDALVSSPQQFDFYDGGGLDVGFLGMAQVDAQGNVNVSRFGSQFPGCGGFINITQNAAA
VVFCGTLTTGGLSVAVADGTITVTSEGAHSKFVEDVEHVTFSADHALETDQSVVYVTERAVFELTPDGLTLTEVAPGIDP
GAVIAQLGFDPAVADPLGVMPARLFADAPPDLTDVV

Specific function: Unknown

COG id: COG4670

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae AtoD [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=523, Percent_Identity=26.9598470363289, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI11545841, Length=490, Percent_Identity=26.3265306122449, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1787985, Length=504, Percent_Identity=43.2539682539683, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1788551, Length=232, Percent_Identity=28.0172413793103, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788552, Length=226, Percent_Identity=28.7610619469027, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531517, Length=500, Percent_Identity=26, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21358325, Length=517, Percent_Identity=25.531914893617, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24655794, Length=517, Percent_Identity=25.531914893617, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014388
- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: NA

Molecular weight: Translated: 53361; Mature: 53361

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTQQSRREAVACVESGDTVGIGGFVATGIPEAVLAALGDRYERTRAPQDLTLYQPAAEG
CCCCHHHHHHHHHEECCCEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
DRQGHGVSHLVQEGMLERTIASHWGFTPDLMAAVVNNEIEAYNLPFGVLDHLLRDTAAGK
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCC
PGTITHVGLDTFVDPRRDGGKANAVTSEDLVERVTLNGTEYLFYHAVPIDVAVIRGTTAD
CCCEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECEEEEEEEECCCCC
EHGNVTMEREALASNMLALAQAAHNTGGRVIAQVERVTSAGTLAPHDVAVPGVVVDSVVE
CCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
ASPEDHPQTYGSAYDPAHSGTVKPPTPSTDPLPIDERTIIARRAAMELDAGAVINLGVGI
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCC
PELVSTAAAEGGVGDAITETVESGPVGGAASGGIEFGTAVNHDALVSSPQQFDFYDGGGL
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCC
DVGFLGMAQVDAQGNVNVSRFGSQFPGCGGFINITQNAAAVVFCGTLTTGGLSVAVADGT
CEEEEEEEEECCCCCCCHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEEECCE
ITVTSEGAHSKFVEDVEHVTFSADHALETDQSVVYVTERAVFELTPDGLTLTEVAPGIDP
EEEECCCCHHHHHHHHHHHEECCCCCCCCCCCEEEEEECEEEEECCCCEEHHHHCCCCCH
GAVIAQLGFDPAVADPLGVMPARLFADAPPDLTDVV
HHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHCC
>Mature Secondary Structure
MVTQQSRREAVACVESGDTVGIGGFVATGIPEAVLAALGDRYERTRAPQDLTLYQPAAEG
CCCCHHHHHHHHHEECCCEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
DRQGHGVSHLVQEGMLERTIASHWGFTPDLMAAVVNNEIEAYNLPFGVLDHLLRDTAAGK
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCC
PGTITHVGLDTFVDPRRDGGKANAVTSEDLVERVTLNGTEYLFYHAVPIDVAVIRGTTAD
CCCEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECEEEEEEEECCCCC
EHGNVTMEREALASNMLALAQAAHNTGGRVIAQVERVTSAGTLAPHDVAVPGVVVDSVVE
CCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
ASPEDHPQTYGSAYDPAHSGTVKPPTPSTDPLPIDERTIIARRAAMELDAGAVINLGVGI
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCC
PELVSTAAAEGGVGDAITETVESGPVGGAASGGIEFGTAVNHDALVSSPQQFDFYDGGGL
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCCCCCCC
DVGFLGMAQVDAQGNVNVSRFGSQFPGCGGFINITQNAAAVVFCGTLTTGGLSVAVADGT
CEEEEEEEEECCCCCCCHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEEECCE
ITVTSEGAHSKFVEDVEHVTFSADHALETDQSVVYVTERAVFELTPDGLTLTEVAPGIDP
EEEECCCCHHHHHHHHHHHEECCCCCCCCCCCEEEEEECEEEEECCCCEEHHHHCCCCCH
GAVIAQLGFDPAVADPLGVMPARLFADAPPDLTDVV
HHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 3541912; 7984428 [H]