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The map label for this gene is hyuB

Identifier: 16119835

GI number: 16119835

Start: 33744

End: 35699

Strand: Direct

Name: hyuB

Synonym: Atu6023

Alternate gene names: NA

Gene position: 33744-35699 (Clockwise)

Preceding gene: 16119834

Following gene: 159161955

Centisome position: 15.75

GC content: 60.07

Gene sequence:

>1956_bases
ATGGATGCCGTTCGTACTGCCGTCATGAACAATCGCTTCAACGCGATTGTCGAAGAAGCCTCTGCCGCGATCTACCGCAC
CGCCCATACGACTTTTGTTAAGATCGTCCAGGATTACCAGTGTGCGATTGCGACTGCCGAAGGCGAAATGTTCGCTTATC
CGATGTTGTCTGGCGTCAATGTCTTCGTCGGCTCCCCGTTGAAGCCGACGCTGGATGCCATCGGCCGGGAGAACCTGAAG
CCAGGCGATATCATCATCACCAACGATCCCTTTGCCACGGACGGTCTGGTGACGCACCTGATGGACGTTACGCTGCTTTA
TCCGATCTTCTTCGACGAGAAGCTGATCGCGATCGGCTGGGCATTTGTCCATGCGTCCGATATCGGCGGCGCCGTTCCGG
GAAGTATCTCGCCAGCCTTCACGGAAGTATTCCAGGAGGGCCTCCGTGTCAGGCCAATGAAGCTCTACGAAGGAGGGGTG
TTGAACGAAGCGATCAAGTCGATCTTCCAGGACAACAGCCGAATTCCGACCGAGTTGTGGGGCGACATTCAGGCCATGAT
CTCGGGCCTGAAGAGCATGGACCGGCGCGTGAGCGAGCTTTGCGAGCGATATGATCGTGAGAGTGTCGAGGAGGGGATGC
AGGACGTCATCAACTACGCGGAGACCAAGGCCCGCGCGGTGATCAGGACGATTCGAGACGGTGTCTATACCTTCTCGGAC
TATCTTGAAGGGATCCATGATGGTCAGCTGGCCTATTTCAGCGTGACCATGACGGTGAAGGACAGCGAGATCGAGGTTGA
TTTTACCGGCACGGATCCGCAATTGGCGGCCGCCTACAACCTGGTAACGGGGGCAACCACCCACCCCTACATTATCCAGT
GCCTTTACGCCTACATCCTGACCGTTGATCCGCTGACGCCGCGCAACTCCGGTATCTTGCGGGCGATCCACGGCCATGCT
CCGCGTGGCACGGTTCTCAACGCGGTCTATCCCGCTTCCGGCGGGTCTCGTGCTGCATCAGCGACACGCGCCTACGACGT
TATCCTGGGGTGCCTCAATCAGGCACTACCGGAGGGCCTTGCCGCAGCCGGTGGCGGTATGAGCGGGGTTATCGTCGTTT
CGGCTCCCGATCCTCGTACAGGCCGTGACCGTGTCAACGTGGTGGGTACGATCGACGGCGGCGGCGGTGCCCGCCGTGGC
GTTGACGGCCTGGACGGATCGGAAGTACGCTACTCACAGCGCAGCGTGCCAGTCGAAGTCATCGAGATCGAAACGGTGCT
AGTCATGCGGGCGCTCCGCCTCGTGCCGGACAGTCGCCGCGCGGGAAGGTTCGCCAGCGGCGCCGCGCTCGAAATTGAAA
TGGAAAACACGTCAAATCGCGCGGTCATAACGGTCAGAAACCTGAACCGGTTTGTGTTCGCGCCGTGGGGCTTCAAGGGG
GGAGAGATCGGTCTTCTGGGTAAGGCAGTCGTCAATCCTGGCCGACCCGATGAGCGATCGGTCGGCAAGATCTCGGTGCT
GGAGCTCGGACAGGGCGATATTCTCAGGATCACCAGTTCCACAGGCGGGGCGTTCGGCGAACCTCTTGAGCGGGATGTGG
CGGCGATCGCGCGCGAGATCGAAAACGGCATGCTTTCCCCGGAGCGGGCCGCCGACGTCTATGCTGTCGTCTTCGACCGG
GACAGTAAGATCGACGAGGCGGCGACCGCAGAACATCGCCGCGAACGCGCAAACCGAAAGTCAGACGACTTTAATTTCTG
CATCGTACGCCAGCGTCAGGACCAGGTGTGGTCGCAGCAGACACGCAGGGAACTGGCATCGCGGGCGTTGACCTATGAAC
AGCGCATCCGCAGCCAGCTCGTCGATCGCGTTCATCACCGCCTGTTGGCGAAAGGTGAGCGGGTTGATGCCGGGAAACTG
GATCAAGTCATTGCCGAAGAAGCCGGCCGGTTGTAG

Upstream 100 bases:

>100_bases
GGCCGTCATCGAGCAGCGTGATGCGACGATCGTCGTTCCGCCAGAGTTCGTTGCCCGCGTCGGAGCCTTTGGCGCAATCC
TCATGACCCGGAGCTGATCA

Downstream 100 bases:

>100_bases
CGGCGATGGTCCTGTGATCGTAATCAGTTAGACTAGTGTGAACGGTCGTCTGAAAGTGCGGCTATTGGGATGCCTCCTCC
AGGGGCATCCTTTGTTCATT

Product: N-methylhydantoinase B/acetone carboxylase, alpha subunit

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MDAVRTAVMNNRFNAIVEEASAAIYRTAHTTFVKIVQDYQCAIATAEGEMFAYPMLSGVNVFVGSPLKPTLDAIGRENLK
PGDIIITNDPFATDGLVTHLMDVTLLYPIFFDEKLIAIGWAFVHASDIGGAVPGSISPAFTEVFQEGLRVRPMKLYEGGV
LNEAIKSIFQDNSRIPTELWGDIQAMISGLKSMDRRVSELCERYDRESVEEGMQDVINYAETKARAVIRTIRDGVYTFSD
YLEGIHDGQLAYFSVTMTVKDSEIEVDFTGTDPQLAAAYNLVTGATTHPYIIQCLYAYILTVDPLTPRNSGILRAIHGHA
PRGTVLNAVYPASGGSRAASATRAYDVILGCLNQALPEGLAAAGGGMSGVIVVSAPDPRTGRDRVNVVGTIDGGGGARRG
VDGLDGSEVRYSQRSVPVEVIEIETVLVMRALRLVPDSRRAGRFASGAALEIEMENTSNRAVITVRNLNRFVFAPWGFKG
GEIGLLGKAVVNPGRPDERSVGKISVLELGQGDILRITSSTGGAFGEPLERDVAAIAREIENGMLSPERAADVYAVVFDR
DSKIDEAATAEHRRERANRKSDDFNFCIVRQRQDQVWSQQTRRELASRALTYEQRIRSQLVDRVHHRLLAKGERVDAGKL
DQVIAEEAGRL

Sequences:

>Translated_651_residues
MDAVRTAVMNNRFNAIVEEASAAIYRTAHTTFVKIVQDYQCAIATAEGEMFAYPMLSGVNVFVGSPLKPTLDAIGRENLK
PGDIIITNDPFATDGLVTHLMDVTLLYPIFFDEKLIAIGWAFVHASDIGGAVPGSISPAFTEVFQEGLRVRPMKLYEGGV
LNEAIKSIFQDNSRIPTELWGDIQAMISGLKSMDRRVSELCERYDRESVEEGMQDVINYAETKARAVIRTIRDGVYTFSD
YLEGIHDGQLAYFSVTMTVKDSEIEVDFTGTDPQLAAAYNLVTGATTHPYIIQCLYAYILTVDPLTPRNSGILRAIHGHA
PRGTVLNAVYPASGGSRAASATRAYDVILGCLNQALPEGLAAAGGGMSGVIVVSAPDPRTGRDRVNVVGTIDGGGGARRG
VDGLDGSEVRYSQRSVPVEVIEIETVLVMRALRLVPDSRRAGRFASGAALEIEMENTSNRAVITVRNLNRFVFAPWGFKG
GEIGLLGKAVVNPGRPDERSVGKISVLELGQGDILRITSSTGGAFGEPLERDVAAIAREIENGMLSPERAADVYAVVFDR
DSKIDEAATAEHRRERANRKSDDFNFCIVRQRQDQVWSQQTRRELASRALTYEQRIRSQLVDRVHHRLLAKGERVDAGKL
DQVIAEEAGRL
>Mature_651_residues
MDAVRTAVMNNRFNAIVEEASAAIYRTAHTTFVKIVQDYQCAIATAEGEMFAYPMLSGVNVFVGSPLKPTLDAIGRENLK
PGDIIITNDPFATDGLVTHLMDVTLLYPIFFDEKLIAIGWAFVHASDIGGAVPGSISPAFTEVFQEGLRVRPMKLYEGGV
LNEAIKSIFQDNSRIPTELWGDIQAMISGLKSMDRRVSELCERYDRESVEEGMQDVINYAETKARAVIRTIRDGVYTFSD
YLEGIHDGQLAYFSVTMTVKDSEIEVDFTGTDPQLAAAYNLVTGATTHPYIIQCLYAYILTVDPLTPRNSGILRAIHGHA
PRGTVLNAVYPASGGSRAASATRAYDVILGCLNQALPEGLAAAGGGMSGVIVVSAPDPRTGRDRVNVVGTIDGGGGARRG
VDGLDGSEVRYSQRSVPVEVIEIETVLVMRALRLVPDSRRAGRFASGAALEIEMENTSNRAVITVRNLNRFVFAPWGFKG
GEIGLLGKAVVNPGRPDERSVGKISVLELGQGDILRITSSTGGAFGEPLERDVAAIAREIENGMLSPERAADVYAVVFDR
DSKIDEAATAEHRRERANRKSDDFNFCIVRQRQDQVWSQQTRRELASRALTYEQRIRSQLVDRVHHRLLAKGERVDAGKL
DQVIAEEAGRL

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=552, Percent_Identity=26.0869565217391, Blast_Score=126, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI133901900, Length=556, Percent_Identity=27.8776978417266, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI133901902, Length=519, Percent_Identity=27.3603082851638, Blast_Score=124, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322634, Length=560, Percent_Identity=25.3571428571429, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550492, Length=561, Percent_Identity=26.0249554367201, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71054; Mature: 71054

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVRTAVMNNRFNAIVEEASAAIYRTAHTTFVKIVQDYQCAIATAEGEMFAYPMLSGVN
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEHHHCCCE
VFVGSPLKPTLDAIGRENLKPGDIIITNDPFATDGLVTHLMDVTLLYPIFFDEKLIAIGW
EEECCCCCHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHEE
AFVHASDIGGAVPGSISPAFTEVFQEGLRVRPMKLYEGGVLNEAIKSIFQDNSRIPTELW
HHEEHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCHHHH
GDIQAMISGLKSMDRRVSELCERYDRESVEEGMQDVINYAETKARAVIRTIRDGVYTFSD
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLEGIHDGQLAYFSVTMTVKDSEIEVDFTGTDPQLAAAYNLVTGATTHPYIIQCLYAYIL
HHCCCCCCCEEEEEEEEEEECCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
TVDPLTPRNSGILRAIHGHAPRGTVLNAVYPASGGSRAASATRAYDVILGCLNQALPEGL
CCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAGGGMSGVIVVSAPDPRTGRDRVNVVGTIDGGGGARRGVDGLDGSEVRYSQRSVPVEV
HHCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEE
IEIETVLVMRALRLVPDSRRAGRFASGAALEIEMENTSNRAVITVRNLNRFVFAPWGFKG
EEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEEEEECCCCCC
GEIGLLGKAVVNPGRPDERSVGKISVLELGQGDILRITSSTGGAFGEPLERDVAAIAREI
CCEEEEEHHHCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
ENGMLSPERAADVYAVVFDRDSKIDEAATAEHRRERANRKSDDFNFCIVRQRQDQVWSQQ
HHCCCCCCHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHH
TRRELASRALTYEQRIRSQLVDRVHHRLLAKGERVDAGKLDQVIAEEAGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MDAVRTAVMNNRFNAIVEEASAAIYRTAHTTFVKIVQDYQCAIATAEGEMFAYPMLSGVN
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEHHHCCCE
VFVGSPLKPTLDAIGRENLKPGDIIITNDPFATDGLVTHLMDVTLLYPIFFDEKLIAIGW
EEECCCCCHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHEE
AFVHASDIGGAVPGSISPAFTEVFQEGLRVRPMKLYEGGVLNEAIKSIFQDNSRIPTELW
HHEEHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCHHHH
GDIQAMISGLKSMDRRVSELCERYDRESVEEGMQDVINYAETKARAVIRTIRDGVYTFSD
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLEGIHDGQLAYFSVTMTVKDSEIEVDFTGTDPQLAAAYNLVTGATTHPYIIQCLYAYIL
HHCCCCCCCEEEEEEEEEEECCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
TVDPLTPRNSGILRAIHGHAPRGTVLNAVYPASGGSRAASATRAYDVILGCLNQALPEGL
CCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAGGGMSGVIVVSAPDPRTGRDRVNVVGTIDGGGGARRGVDGLDGSEVRYSQRSVPVEV
HHCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEE
IEIETVLVMRALRLVPDSRRAGRFASGAALEIEMENTSNRAVITVRNLNRFVFAPWGFKG
EEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEEEEECCCCCC
GEIGLLGKAVVNPGRPDERSVGKISVLELGQGDILRITSSTGGAFGEPLERDVAAIAREI
CCEEEEEHHHCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
ENGMLSPERAADVYAVVFDRDSKIDEAATAEHRRERANRKSDDFNFCIVRQRQDQVWSQQ
HHCCCCCCHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHH
TRRELASRALTYEQRIRSQLVDRVHHRLLAKGERVDAGKLDQVIAEEAGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]