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The map label for this gene is virG

Identifier: 16119794

GI number: 16119794

Start: 193546

End: 194307

Strand: Direct

Name: virG

Synonym: Atu6178

Alternate gene names: 16119794

Gene position: 193546-194307 (Clockwise)

Preceding gene: 41223310

Following gene: 41223311

Centisome position: 90.34

GC content: 53.81

Gene sequence:

>762_bases
ATGGCTGGCCAGGATCCTAGATTGAGAGGTGAACCGTTGAAACACGTTCTTGTCATCGATGACGATGTCGCTATGCGGCA
TCTTATAGTCGAGTATCTTACGATCCATGCCTTTAAGGTGACTGCGGTAGCCGACAGCAAGCAGTTCAATCGTGTACTCT
GCTCCGAGACGGTCGATGTCGTGGTCGTCGATCTTAATTTGGGTCGCGAAGATGGGCTTGAAATTGTTCGTAGTCTGGCC
ACGAAGTCCGATGTTCCAATCATAATTATTAGCGGCGCTCGCCTCGAAGAGGCGGACAAAGTTATTGCGCTCGAGTTGGG
AGCAACCGATTTTATTGCCAAGCCTTTTGGGACGCGGGAATTTCTGGCGCGCATCCGTGTTGCGTTACGCGTGCGGCCCA
GTGTCGCGCGAACCAAAGATCGACGCTCATTTAGTTTCGCTGACTGGACACTTAATCTCAGGCGACGCCGCTTGATTTCG
GAAGAGGGCAGTGAGGTGAAACTCACGGCAGGTGAGTTTAATCTCCTGGTTGCTTTCCTGGAGAAGCCGCGCGACGTCCT
ATCCCGGGAGCAGCTTCTGATCGCCAGTCGGGTACGCGAGGAGGAGGTGTATGACAGAAGTATTGATGTCCTCATTTTGC
GGCTGCGCCGGAAGCTTGAGGGGGATCCGACGACCCCTCAGTTGATCAAGACTGCAAGAGGTGCTGGCTATTTCTTTGAC
GCTGACGTGGATGTTTCGTACGGGGGTGTGATGGCGGCCTGA

Upstream 100 bases:

>100_bases
TGGTCGAAATCTTGCCGAAATGCCCGTGTAGTGAGAGAAAATTAAAGAGTGGAGTCTAGCAAATACAACCTTTACGTGTA
TAAATTCTGTTGAGCTGCAA

Downstream 100 bases:

>100_bases
GGTAGAGGTGCATTTCGCCTTTAGCAATCTGTTCCCAACGTGAGCAGATTGCTATGCGGCTTGGCAAAGCTGCCTTTCCT
CGGTACTATCCGAAAAACTC

Product: two-component response regulator VirG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MAGQDPRLRGEPLKHVLVIDDDVAMRHLIVEYLTIHAFKVTAVADSKQFNRVLCSETVDVVVVDLNLGREDGLEIVRSLA
TKSDVPIIIISGARLEEADKVIALELGATDFIAKPFGTREFLARIRVALRVRPSVARTKDRRSFSFADWTLNLRRRRLIS
EEGSEVKLTAGEFNLLVAFLEKPRDVLSREQLLIASRVREEEVYDRSIDVLILRLRRKLEGDPTTPQLIKTARGAGYFFD
ADVDVSYGGVMAA

Sequences:

>Translated_253_residues
MAGQDPRLRGEPLKHVLVIDDDVAMRHLIVEYLTIHAFKVTAVADSKQFNRVLCSETVDVVVVDLNLGREDGLEIVRSLA
TKSDVPIIIISGARLEEADKVIALELGATDFIAKPFGTREFLARIRVALRVRPSVARTKDRRSFSFADWTLNLRRRRLIS
EEGSEVKLTAGEFNLLVAFLEKPRDVLSREQLLIASRVREEEVYDRSIDVLILRLRRKLEGDPTTPQLIKTARGAGYFFD
ADVDVSYGGVMAA
>Mature_252_residues
AGQDPRLRGEPLKHVLVIDDDVAMRHLIVEYLTIHAFKVTAVADSKQFNRVLCSETVDVVVVDLNLGREDGLEIVRSLAT
KSDVPIIIISGARLEEADKVIALELGATDFIAKPFGTREFLARIRVALRVRPSVARTKDRRSFSFADWTLNLRRRRLISE
EGSEVKLTAGEFNLLVAFLEKPRDVLSREQLLIASRVREEEVYDRSIDVLILRLRRKLEGDPTTPQLIKTARGAGYFFDA
DVDVSYGGVMAA

Specific function: VirG is required for the positive regulation of at least two vir loci encoded by the Ti plasmid of A.tumefaciens

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=42.6086956521739, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=32.0512820512821, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=34.8936170212766, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=33.4782608695652, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.2422907488987, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=30.7359307359307, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=31.2775330396476, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=30.7359307359307, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=32.3144104803493, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=30.3418803418803, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790860, Length=186, Percent_Identity=35.4838709677419, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=28.0701754385965, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=30.1801801801802, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=28.5087719298246, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VIRG_AGRT5 (P07545)

Other databases:

- EMBL:   M36786
- EMBL:   Y00535
- EMBL:   J03320
- EMBL:   U16142
- EMBL:   AE007871
- PIR:   AH3249
- PIR:   S03760
- RefSeq:   NP_053392.1
- RefSeq:   NP_396499.1
- ProteinModelPortal:   P07545
- SMR:   P07545
- STRING:   P07545
- GeneID:   1137501
- GeneID:   1224146
- GenomeReviews:   AE007871_GR
- KEGG:   atu:Atu6178
- eggNOG:   COG0745
- HOGENOM:   HBG753323
- OMA:   FLARIRV
- ProtClustDB:   PRK13856
- BioCyc:   ATUM176299-1:ATU6178-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 28416; Mature: 28285

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQDPRLRGEPLKHVLVIDDDVAMRHLIVEYLTIHAFKVTAVADSKQFNRVLCSETVDV
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHCCCEEE
VVVDLNLGREDGLEIVRSLATKSDVPIIIISGARLEEADKVIALELGATDFIAKPFGTRE
EEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCHHHCCCCCHHH
FLARIRVALRVRPSVARTKDRRSFSFADWTLNLRRRRLISEEGSEVKLTAGEFNLLVAFL
HHHHHHHHHEECCHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
EKPRDVLSREQLLIASRVREEEVYDRSIDVLILRLRRKLEGDPTTPQLIKTARGAGYFFD
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEE
ADVDVSYGGVMAA
CCCCCCCCCEECC
>Mature Secondary Structure 
AGQDPRLRGEPLKHVLVIDDDVAMRHLIVEYLTIHAFKVTAVADSKQFNRVLCSETVDV
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHCCCEEE
VVVDLNLGREDGLEIVRSLATKSDVPIIIISGARLEEADKVIALELGATDFIAKPFGTRE
EEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCHHHCCCCCHHH
FLARIRVALRVRPSVARTKDRRSFSFADWTLNLRRRRLISEEGSEVKLTAGEFNLLVAFL
HHHHHHHHHEECCHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
EKPRDVLSREQLLIASRVREEEVYDRSIDVLILRLRRKLEGDPTTPQLIKTARGAGYFFD
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEE
ADVDVSYGGVMAA
CCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3448462; 2194232; 7601840; 11743193; 11743194