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The map label for this gene is ndhF [H]

Identifier: 160903173

GI number: 160903173

Start: 1904185

End: 1905102

Strand: Direct

Name: ndhF [H]

Synonym: Pmob_1738

Alternate gene names: 160903173

Gene position: 1904185-1905102 (Clockwise)

Preceding gene: 160903172

Following gene: 160903174

Centisome position: 87.77

GC content: 36.49

Gene sequence:

>918_bases
ATGAAAGAATACACAGGAGAACTAGGGAGCAAGCAAGAAGATTTTGGGAGAGATTCTGATGATTACTTTGCTCCCACCAC
ATTGAAAGAAGCCACAGAGATTCTCGCAAAATACAGCCCCAACATCAAAATCATCGCAGGGGGCACAGATCTTCTGGTGG
ATTATTTTGACCGCCTTTATGAAGTAGACAGGTGGATCAGCTTAAAGAACCTCGATGAACTAAAAAAAATTGAAATAAAC
AACGATCGAATAGAAGTTGGTGCTCTAGTCACACACGAGGAATTAGTAAAATCTGAAATTATACAAAAATATTTACCGCT
AATAAGTCAAGCTGCCTTAGATGTTGGTTCACCACAAATCAGAAACAGGGGTACCATTGGTGGTAATATTGCAAATTCTT
CCCCAGCAGGAGATTTATTACCTCCCTTAATAGCTTACGATGCTGTATTCAAAATAACTTCCCAAAATGAAACCCGTGAG
GTACCTGCAAAAGAGTTTTTCCTAGGACCTAAAAAAAACGTACTTAGAAATGATGAAATTTTAGAAAAAATTATCATTCC
AATACCTCAAAAACACACTTATGGAAAATGGTTAAAAGTTGGAAAAAGAAACGCCTTGATAATTTCAAGTATAACGTTGG
CTATTGTTGTGACCTTCAATGATGATGAACGCATAAAAACAGTGAAATGTTCTCTTGGTTCTGTAGCTCCAGTTCCAATT
GAGATATCTCAAATTCAACCTCTTATGGTTGAAAAAAGGTTTAACGAATTAGACTATTCTCAGATTGGAAAAGTAGTCTC
CAATAACATTTCACCAATAGATGACATAAGAGGTACCAAAGAATATCGGAGGGAAGTTGCTAAAAATCTAACAATTAGCG
CATTAAACGAAATAGAAAGGATGGTGAGGGTAGATTGA

Upstream 100 bases:

>100_bases
TATTCTCATATCCTTTTTGGAATGAACGGGGGAATGGTTGAAACTGTAATTATTGACGGCAAAATTATTATGGATGATCG
GGAGGTGACGATTTTAGATT

Downstream 100 bases:

>100_bases
AAATAAGCTTTACCATAAATGGTATTAAAAGAGAATGCAATGTAAATTCAACTACCCGTTTGTTAGACTTAATTAGGGAC
GATCTGAATCTTACAGGTAC

Product: FAD-binding molybdopterin dehydrogenase

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase FAD-subunit; NAH [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKEYTGELGSKQEDFGRDSDDYFAPTTLKEATEILAKYSPNIKIIAGGTDLLVDYFDRLYEVDRWISLKNLDELKKIEIN
NDRIEVGALVTHEELVKSEIIQKYLPLISQAALDVGSPQIRNRGTIGGNIANSSPAGDLLPPLIAYDAVFKITSQNETRE
VPAKEFFLGPKKNVLRNDEILEKIIIPIPQKHTYGKWLKVGKRNALIISSITLAIVVTFNDDERIKTVKCSLGSVAPVPI
EISQIQPLMVEKRFNELDYSQIGKVVSNNISPIDDIRGTKEYRREVAKNLTISALNEIERMVRVD

Sequences:

>Translated_305_residues
MKEYTGELGSKQEDFGRDSDDYFAPTTLKEATEILAKYSPNIKIIAGGTDLLVDYFDRLYEVDRWISLKNLDELKKIEIN
NDRIEVGALVTHEELVKSEIIQKYLPLISQAALDVGSPQIRNRGTIGGNIANSSPAGDLLPPLIAYDAVFKITSQNETRE
VPAKEFFLGPKKNVLRNDEILEKIIIPIPQKHTYGKWLKVGKRNALIISSITLAIVVTFNDDERIKTVKCSLGSVAPVPI
EISQIQPLMVEKRFNELDYSQIGKVVSNNISPIDDIRGTKEYRREVAKNLTISALNEIERMVRVD
>Mature_305_residues
MKEYTGELGSKQEDFGRDSDDYFAPTTLKEATEILAKYSPNIKIIAGGTDLLVDYFDRLYEVDRWISLKNLDELKKIEIN
NDRIEVGALVTHEELVKSEIIQKYLPLISQAALDVGSPQIRNRGTIGGNIANSSPAGDLLPPLIAYDAVFKITSQNETRE
VPAKEFFLGPKKNVLRNDEILEKIIIPIPQKHTYGKWLKVGKRNALIISSITLAIVVTFNDDERIKTVKCSLGSVAPVPI
EISQIQPLMVEKRFNELDYSQIGKVVSNNISPIDDIRGTKEYRREVAKNLTISALNEIERMVRVD

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=304, Percent_Identity=24.3421052631579, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1789231, Length=285, Percent_Identity=30.8771929824561, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789245, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540638, Length=261, Percent_Identity=23.3716475095785, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17737937, Length=258, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 34314; Mature: 34314

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYTGELGSKQEDFGRDSDDYFAPTTLKEATEILAKYSPNIKIIAGGTDLLVDYFDRLY
CCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
EVDRWISLKNLDELKKIEINNDRIEVGALVTHEELVKSEIIQKYLPLISQAALDVGSPQI
HHHHHHCCCCHHHHHHEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RNRGTIGGNIANSSPAGDLLPPLIAYDAVFKITSQNETREVPAKEFFLGPKKNVLRNDEI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCHHHHCCCCCHHHHCCHHH
LEKIIIPIPQKHTYGKWLKVGKRNALIISSITLAIVVTFNDDERIKTVKCSLGSVAPVPI
HHHHHCCCCCCCCCHHHHHHCCCCEEEEEEEEEEEEEEECCCCCEEEEEECCCCCCCCCE
EISQIQPLMVEKRFNELDYSQIGKVVSNNISPIDDIRGTKEYRREVAKNLTISALNEIER
EHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHH
MVRVD
HHCCC
>Mature Secondary Structure
MKEYTGELGSKQEDFGRDSDDYFAPTTLKEATEILAKYSPNIKIIAGGTDLLVDYFDRLY
CCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
EVDRWISLKNLDELKKIEINNDRIEVGALVTHEELVKSEIIQKYLPLISQAALDVGSPQI
HHHHHHCCCCHHHHHHEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RNRGTIGGNIANSSPAGDLLPPLIAYDAVFKITSQNETREVPAKEFFLGPKKNVLRNDEI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCHHHHCCCCCHHHHCCHHH
LEKIIIPIPQKHTYGKWLKVGKRNALIISSITLAIVVTFNDDERIKTVKCSLGSVAPVPI
HHHHHCCCCCCCCCHHHHHHCCCCEEEEEEEEEEEEEEECCCCCEEEEEECCCCCCCCCE
EISQIQPLMVEKRFNELDYSQIGKVVSNNISPIDDIRGTKEYRREVAKNLTISALNEIER
EHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHH
MVRVD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA