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The map label for this gene is cutS [H]

Identifier: 160903174

GI number: 160903174

Start: 1905099

End: 1905593

Strand: Direct

Name: cutS [H]

Synonym: Pmob_1739

Alternate gene names: 160903174

Gene position: 1905099-1905593 (Clockwise)

Preceding gene: 160903173

Following gene: 160903175

Centisome position: 87.81

GC content: 35.15

Gene sequence:

>495_bases
TTGAAAATAAGCTTTACCATAAATGGTATTAAAAGAGAATGCAATGTAAATTCAACTACCCGTTTGTTAGACTTAATTAG
GGACGATCTGAATCTTACAGGTACAAAAGAAGGTTGTGGAAAAGGAGAATGTGGTGCATGTACGGTTATAATGAATGATA
AAATCGTAGCTTCTTGCTTAGTGCTTGCATACGAAGCAGATGGCGCAGAAATAGTTACTATTGAAGGTTTGAGTGATAAA
AATATTTTACATCCTATACAAGAGGCATACATTGAAACTGGAGCTGTACAATGTGGTTTTTGCACACCTGGATTTATACT
AGCAACTAAAAAACTTCTTGACGAAAATCCAAACCCAACGGAAGAGGAAATAAAAATAGGTTTATCTGGCAATATCTGTA
GATGTACTGGATACCAAAAAATAATAGATGCGGTCAAACTCTCGGCCACTAAAATTGCTGAGTATAAGAGAGGTGAGAAA
GTTGAAACCAAATAA

Upstream 100 bases:

>100_bases
CAATAGATGACATAAGAGGTACCAAAGAATATCGGAGGGAAGTTGCTAAAAATCTAACAATTAGCGCATTAAACGAAATA
GAAAGGATGGTGAGGGTAGA

Downstream 100 bases:

>100_bases
ATACGTTGGAGAGAATGTTTTCAAAGTTGATGCCAAAGACAAAGTATTGGGTAAAGCCATCTATCCGGATGATATATACT
TTGAGGATATGCTCTATGTG

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKISFTINGIKRECNVNSTTRLLDLIRDDLNLTGTKEGCGKGECGACTVIMNDKIVASCLVLAYEADGAEIVTIEGLSDK
NILHPIQEAYIETGAVQCGFCTPGFILATKKLLDENPNPTEEEIKIGLSGNICRCTGYQKIIDAVKLSATKIAEYKRGEK
VETK

Sequences:

>Translated_164_residues
MKISFTINGIKRECNVNSTTRLLDLIRDDLNLTGTKEGCGKGECGACTVIMNDKIVASCLVLAYEADGAEIVTIEGLSDK
NILHPIQEAYIETGAVQCGFCTPGFILATKKLLDENPNPTEEEIKIGLSGNICRCTGYQKIIDAVKLSATKIAEYKRGEK
VETK
>Mature_164_residues
MKISFTINGIKRECNVNSTTRLLDLIRDDLNLTGTKEGCGKGECGACTVIMNDKIVASCLVLAYEADGAEIVTIEGLSDK
NILHPIQEAYIETGAVQCGFCTPGFILATKKLLDENPNPTEEEIKIGLSGNICRCTGYQKIIDAVKLSATKIAEYKRGEK
VETK

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=41.875, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI71773480, Length=154, Percent_Identity=42.8571428571429, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=40.7185628742515, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=47.2972972972973, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1789246, Length=151, Percent_Identity=32.4503311258278, Blast_Score=77, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540638, Length=152, Percent_Identity=44.7368421052632, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=40.6451612903226, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=37.012987012987, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17737937, Length=168, Percent_Identity=38.0952380952381, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=38.7096774193548, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=34.7826086956522, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=34.7826086956522, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=39.3548387096774, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647193, Length=156, Percent_Identity=37.1794871794872, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17791; Mature: 17791

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISFTINGIKRECNVNSTTRLLDLIRDDLNLTGTKEGCGKGECGACTVIMNDKIVASCL
CEEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHE
VLAYEADGAEIVTIEGLSDKNILHPIQEAYIETGAVQCGFCTPGFILATKKLLDENPNPT
EEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHCCCCCCC
EEEIKIGLSGNICRCTGYQKIIDAVKLSATKIAEYKRGEKVETK
HHHEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKISFTINGIKRECNVNSTTRLLDLIRDDLNLTGTKEGCGKGECGACTVIMNDKIVASCL
CEEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHE
VLAYEADGAEIVTIEGLSDKNILHPIQEAYIETGAVQCGFCTPGFILATKKLLDENPNPT
EEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHCCCCCCC
EEEIKIGLSGNICRCTGYQKIIDAVKLSATKIAEYKRGEKVETK
HHHEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]