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The map label for this gene is thrC [H]

Identifier: 160903163

GI number: 160903163

Start: 1891989

End: 1893254

Strand: Direct

Name: thrC [H]

Synonym: Pmob_1728

Alternate gene names: 160903163

Gene position: 1891989-1893254 (Clockwise)

Preceding gene: 160903162

Following gene: 160903164

Centisome position: 87.21

GC content: 37.12

Gene sequence:

>1266_bases
TTGGAGGGGAGAAAACTGAAATATGTAAAAGATTTGGTTTGTATTTCTTGTGGGGAAAAATACGAAGCTTCACCAACACA
ATATCTTTGCCCAAAATGTGGAGAAAAAGGTATTTTAGATGTTGAATACGATTACGAAAAGATAAAAAAAGATTGGAATA
AGCAAGATTTAAAAGCAAATCCTGATCCATCTATATGGAGATATTCACCACTCTTACCTATAGAACCTAACACCCCTAAA
CCCCCTTTGAAGATTGGAGGCACACCTTTATACAAAAGTGATGTTATGGCGAAACTGTTAGGTATAGAAACCCTTTACAT
TAAAGATGATGGTTTAAATCCAACAGGATCTTTGAAAGATAGGGCTTCAGCTATAGCTGTTGTAAAAGCACAAGAGGCAG
GCATGAACATCGTTGCCTGCGCTTCTACTGGGAACGCTGCCTCTTCGTTGGCGGGGAACATAGCATCTATGGGAAATGAA
ATGAAGGCTGTTATTTTTGTTCCCTCGCGAGCCCCAATTGGAAAAGTTACTCAGCTATTGGTTTTTGGAGCTTTAGTTTT
ATCAGTAAAGGGGTCTTATGAAGAAACTTTTTATCTATCACAACAAGCTATTGATAAGTGGGGCTGGTATAACAGAAACG
CTGCGATAAACCCCTACTTAGTTGAAGGTAAAAAAACTTCTTCAATTGAAATCGCTGAACAATTAAATTGGGAAATGGTT
GATTGGTTAGTTTACTCCGTGGGTGATGGCTGCACAATAGCAGGTGCTTGGAAAGGTATGTATGATTTAAAACAAATAGG
ATTCATCGATAAACTACCAAGGCTATTAGGGGTGCAATCTGAAGGCTGTGCGCCAATTACTCAGGCATTTAAAAGCGATA
CAGATCTTGTTCCAGTTCCCGAAAATACCATCGCTGATAGCATTGCTGTTGGAAAACCTCGAAATTATATAAAAGCTATT
AAAGCAGTTAAAGATTCAAATGGTGATATGATCAATGTAACAGATGATGAAATACTAAATATGATAAAAATTTTAGGAAA
GAATACTGGCATTTTTGGTGAACCTGCAGGAGTTGCAGGAGTGGCTGGTATAAAAAAAGCTGTTGAAAACGGCATAATCA
AACCTTCTGAAAGTGTTGCGGTTGTTGTTACTGGGAACGGTCTGAAAGATATTAAAAATGCTGAAAAAGCAACGGGCGCT
CCTTTGTCTTTAGATCCGAATTTAAATGAATTATCTCAACTATTAGAAAAATATAATTTTAAATAA

Upstream 100 bases:

>100_bases
TACAACGATGAAAAATATTGGGGTAATGCCTTTGAAATTGCAGACAAAATCGATCAATTAATAAATGAATTTAACAAAAA
AACGGGATTATTAGGCTAAA

Downstream 100 bases:

>100_bases
CTTATTAAATAGTTGAACGAGATTTATTTCTATCATAAAAAAAACAGCAATAAGCAATAAAACTATCAGATAAAAGGGGG
TTCATTAAAATATATGAATT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MEGRKLKYVKDLVCISCGEKYEASPTQYLCPKCGEKGILDVEYDYEKIKKDWNKQDLKANPDPSIWRYSPLLPIEPNTPK
PPLKIGGTPLYKSDVMAKLLGIETLYIKDDGLNPTGSLKDRASAIAVVKAQEAGMNIVACASTGNAASSLAGNIASMGNE
MKAVIFVPSRAPIGKVTQLLVFGALVLSVKGSYEETFYLSQQAIDKWGWYNRNAAINPYLVEGKKTSSIEIAEQLNWEMV
DWLVYSVGDGCTIAGAWKGMYDLKQIGFIDKLPRLLGVQSEGCAPITQAFKSDTDLVPVPENTIADSIAVGKPRNYIKAI
KAVKDSNGDMINVTDDEILNMIKILGKNTGIFGEPAGVAGVAGIKKAVENGIIKPSESVAVVVTGNGLKDIKNAEKATGA
PLSLDPNLNELSQLLEKYNFK

Sequences:

>Translated_421_residues
MEGRKLKYVKDLVCISCGEKYEASPTQYLCPKCGEKGILDVEYDYEKIKKDWNKQDLKANPDPSIWRYSPLLPIEPNTPK
PPLKIGGTPLYKSDVMAKLLGIETLYIKDDGLNPTGSLKDRASAIAVVKAQEAGMNIVACASTGNAASSLAGNIASMGNE
MKAVIFVPSRAPIGKVTQLLVFGALVLSVKGSYEETFYLSQQAIDKWGWYNRNAAINPYLVEGKKTSSIEIAEQLNWEMV
DWLVYSVGDGCTIAGAWKGMYDLKQIGFIDKLPRLLGVQSEGCAPITQAFKSDTDLVPVPENTIADSIAVGKPRNYIKAI
KAVKDSNGDMINVTDDEILNMIKILGKNTGIFGEPAGVAGVAGIKKAVENGIIKPSESVAVVVTGNGLKDIKNAEKATGA
PLSLDPNLNELSQLLEKYNFK
>Mature_421_residues
MEGRKLKYVKDLVCISCGEKYEASPTQYLCPKCGEKGILDVEYDYEKIKKDWNKQDLKANPDPSIWRYSPLLPIEPNTPK
PPLKIGGTPLYKSDVMAKLLGIETLYIKDDGLNPTGSLKDRASAIAVVKAQEAGMNIVACASTGNAASSLAGNIASMGNE
MKAVIFVPSRAPIGKVTQLLVFGALVLSVKGSYEETFYLSQQAIDKWGWYNRNAAINPYLVEGKKTSSIEIAEQLNWEMV
DWLVYSVGDGCTIAGAWKGMYDLKQIGFIDKLPRLLGVQSEGCAPITQAFKSDTDLVPVPENTIADSIAVGKPRNYIKAI
KAVKDSNGDMINVTDDEILNMIKILGKNTGIFGEPAGVAGVAGIKKAVENGIIKPSESVAVVVTGNGLKDIKNAEKATGA
PLSLDPNLNELSQLLEKYNFK

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. Does not catalyze the conversion of O-acetyl-L- homoserine into threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 45543; Mature: 45543

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGRKLKYVKDLVCISCGEKYEASPTQYLCPKCGEKGILDVEYDYEKIKKDWNKQDLKAN
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCEEEEECCHHHHHHCCCCCCCCCC
PDPSIWRYSPLLPIEPNTPKPPLKIGGTPLYKSDVMAKLLGIETLYIKDDGLNPTGSLKD
CCCCCEEECCEEECCCCCCCCCCEECCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCHH
RASAIAVVKAQEAGMNIVACASTGNAASSLAGNIASMGNEMKAVIFVPSRAPIGKVTQLL
HHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
VFGALVLSVKGSYEETFYLSQQAIDKWGWYNRNAAINPYLVEGKKTSSIEIAEQLNWEMV
HHHHHHHHCCCCCCHHEEEHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHCCHHHH
DWLVYSVGDGCTIAGAWKGMYDLKQIGFIDKLPRLLGVQSEGCAPITQAFKSDTDLVPVP
HHHHHHCCCCCEEEHHHCCHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECC
ENTIADSIAVGKPRNYIKAIKAVKDSNGDMINVTDDEILNMIKILGKNTGIFGEPAGVAG
CCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCHHH
VAGIKKAVENGIIKPSESVAVVVTGNGLKDIKNAEKATGAPLSLDPNLNELSQLLEKYNF
HHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCC
K
C
>Mature Secondary Structure
MEGRKLKYVKDLVCISCGEKYEASPTQYLCPKCGEKGILDVEYDYEKIKKDWNKQDLKAN
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCEEEEECCHHHHHHCCCCCCCCCC
PDPSIWRYSPLLPIEPNTPKPPLKIGGTPLYKSDVMAKLLGIETLYIKDDGLNPTGSLKD
CCCCCEEECCEEECCCCCCCCCCEECCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCHH
RASAIAVVKAQEAGMNIVACASTGNAASSLAGNIASMGNEMKAVIFVPSRAPIGKVTQLL
HHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
VFGALVLSVKGSYEETFYLSQQAIDKWGWYNRNAAINPYLVEGKKTSSIEIAEQLNWEMV
HHHHHHHHCCCCCCHHEEEHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHCCHHHH
DWLVYSVGDGCTIAGAWKGMYDLKQIGFIDKLPRLLGVQSEGCAPITQAFKSDTDLVPVP
HHHHHHCCCCCEEEHHHCCHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECC
ENTIADSIAVGKPRNYIKAIKAVKDSNGDMINVTDDEILNMIKILGKNTGIFGEPAGVAG
CCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCHHH
VAGIKKAVENGIIKPSESVAVVVTGNGLKDIKNAEKATGAPLSLDPNLNELSQLLEKYNF
HHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]