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The map label for this gene is cysK [H]

Identifier: 160903162

GI number: 160903162

Start: 1890521

End: 1891987

Strand: Direct

Name: cysK [H]

Synonym: Pmob_1727

Alternate gene names: 160903162

Gene position: 1890521-1891987 (Clockwise)

Preceding gene: 160903161

Following gene: 160903163

Centisome position: 87.14

GC content: 36.88

Gene sequence:

>1467_bases
ATGATAGATTTTACTATGGACAAAGAGGTACTCGAAAAAGCAGTAGAAAGGGCTATAGAGAATAATATTATTATACCTAC
CTTTGCACAGATGCGAGATCCAGCTTTGATTCCTGATAAAATCAAACAACAGCTAAAAAATATAGGTTTATGGGATGTTA
ATTCATACAACTTATTTAGAATTACATGGAAAAACGAACCAGTTCCAAAAGGTGGTTTATATGGTGATGTAAATTACTTT
GAGTTACCATCTGAATTAACGGGCGTTAAAGCTCGAATCGTGGCATTGGTAGGTAAATGGTTCCCAACCGGCTCCCACAA
GGTTGGTGCCACCTTTGGGTGCCTTGTACCAAGGCTTGTAACCGGTCAATTTGATCCTACTACTCAAAAAGCCGTTTGGC
CTTCAACAGGAAATTATTGTCGCGGAGGAGCTTATAACGCCCAGCTTTTAGGATGTGAATCCATAGCTATATTGCCTGAA
GGTATGAGTAGAGAAAGATTCGAATGGTTATCAAAAGTTGCGGGGGAAGTAATAGGAACACCCGGAAGTGAGAGTAACGT
AAAAGAGATATTCGATAAATGTAATGAATTAAAGTCTACTCACGACAATATTGTTATTTTCAACCAGTTTGATGAAATGG
GCAATCGTTTGTGGCATTATGTAGTTACCGGGCCTGCTATGGAAGAGGTGCTGCAAAAAATTATGGGGGAAAAAGACAGA
TTGGCAGGAACCGTCCTCACTTCAGGATCTTCTGGAACGTTGGGTTCAGGAGAATATTTAAAATCTAAGTACCCAAATAG
TAAATTAGCTGTCTCAGAGGCACTGCAGTGTCCCACTTTATTATACAACGGATTTGGTGCCCATCGAATTGAGGGCATAG
GAGATAAACATGTGCCTTGGATTCATAACGTTAAAAATACCGATATGGTTATGGCAATAGATGACAATGATGCTATGAAT
TTAATAAGGCTTTTCAACGAACCTGAAGGGAAAGACTTTTTAAGAAAACAGGGAGTCTCTTCGTCGATAGTAAATAATTT
ATCTTTACTGGGAATCTCTTCTATTGCAAATGTTCTTTCTGCTATAAAATTTGCCAAATACTACGAATTAACAGATAAAG
ATGTTGTGATGACCGTATTCACTGATTCAATGGAATTATACGATTCTAGGCTTAAAGAGTTACAAGAGCAAAAAGGTAAA
TATTCTGAACAGCAGGCTGCTGTAGATTTTGAGAAGCATCTAATGGGGGTAAAAACAGACTTTATTCAGGAACTGAGTTA
TTATGATAAAAAAAGAATACACAATTTAAAATACTATACTTGGATAGAACAGCAGGGTAAAGAATTAGAAGAATTGAACG
AGCAATGGTACAACGATGAAAAATATTGGGGTAATGCCTTTGAAATTGCAGACAAAATCGATCAATTAATAAATGAATTT
AACAAAAAAACGGGATTATTAGGCTAA

Upstream 100 bases:

>100_bases
AAAAAGGCTTTGATCTTGAAAGTACATCACTGTGAAGCCTTTTTGATTCCAAGTATGAGAACATATCTAAAAAATATTTA
AAAGACCTAGGAGGAATAAG

Downstream 100 bases:

>100_bases
ATTGGAGGGGAGAAAACTGAAATATGTAAAAGATTTGGTTTGTATTTCTTGTGGGGAAAAATACGAAGCTTCACCAACAC
AATATCTTTGCCCAAAATGT

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: CSase; O-acetylserine (thiol)-lyase; OAS-TL; O-acetylserine sulfhydrylase [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MIDFTMDKEVLEKAVERAIENNIIIPTFAQMRDPALIPDKIKQQLKNIGLWDVNSYNLFRITWKNEPVPKGGLYGDVNYF
ELPSELTGVKARIVALVGKWFPTGSHKVGATFGCLVPRLVTGQFDPTTQKAVWPSTGNYCRGGAYNAQLLGCESIAILPE
GMSRERFEWLSKVAGEVIGTPGSESNVKEIFDKCNELKSTHDNIVIFNQFDEMGNRLWHYVVTGPAMEEVLQKIMGEKDR
LAGTVLTSGSSGTLGSGEYLKSKYPNSKLAVSEALQCPTLLYNGFGAHRIEGIGDKHVPWIHNVKNTDMVMAIDDNDAMN
LIRLFNEPEGKDFLRKQGVSSSIVNNLSLLGISSIANVLSAIKFAKYYELTDKDVVMTVFTDSMELYDSRLKELQEQKGK
YSEQQAAVDFEKHLMGVKTDFIQELSYYDKKRIHNLKYYTWIEQQGKELEELNEQWYNDEKYWGNAFEIADKIDQLINEF
NKKTGLLG

Sequences:

>Translated_488_residues
MIDFTMDKEVLEKAVERAIENNIIIPTFAQMRDPALIPDKIKQQLKNIGLWDVNSYNLFRITWKNEPVPKGGLYGDVNYF
ELPSELTGVKARIVALVGKWFPTGSHKVGATFGCLVPRLVTGQFDPTTQKAVWPSTGNYCRGGAYNAQLLGCESIAILPE
GMSRERFEWLSKVAGEVIGTPGSESNVKEIFDKCNELKSTHDNIVIFNQFDEMGNRLWHYVVTGPAMEEVLQKIMGEKDR
LAGTVLTSGSSGTLGSGEYLKSKYPNSKLAVSEALQCPTLLYNGFGAHRIEGIGDKHVPWIHNVKNTDMVMAIDDNDAMN
LIRLFNEPEGKDFLRKQGVSSSIVNNLSLLGISSIANVLSAIKFAKYYELTDKDVVMTVFTDSMELYDSRLKELQEQKGK
YSEQQAAVDFEKHLMGVKTDFIQELSYYDKKRIHNLKYYTWIEQQGKELEELNEQWYNDEKYWGNAFEIADKIDQLINEF
NKKTGLLG
>Mature_488_residues
MIDFTMDKEVLEKAVERAIENNIIIPTFAQMRDPALIPDKIKQQLKNIGLWDVNSYNLFRITWKNEPVPKGGLYGDVNYF
ELPSELTGVKARIVALVGKWFPTGSHKVGATFGCLVPRLVTGQFDPTTQKAVWPSTGNYCRGGAYNAQLLGCESIAILPE
GMSRERFEWLSKVAGEVIGTPGSESNVKEIFDKCNELKSTHDNIVIFNQFDEMGNRLWHYVVTGPAMEEVLQKIMGEKDR
LAGTVLTSGSSGTLGSGEYLKSKYPNSKLAVSEALQCPTLLYNGFGAHRIEGIGDKHVPWIHNVKNTDMVMAIDDNDAMN
LIRLFNEPEGKDFLRKQGVSSSIVNNLSLLGISSIANVLSAIKFAKYYELTDKDVVMTVFTDSMELYDSRLKELQEQKGK
YSEQQAAVDFEKHLMGVKTDFIQELSYYDKKRIHNLKYYTWIEQQGKELEELNEQWYNDEKYWGNAFEIADKIDQLINEF
NKKTGLLG

Specific function: Cysteine biosynthesis. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788754, Length=268, Percent_Identity=26.865671641791, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17535051, Length=262, Percent_Identity=29.7709923664122, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562970, Length=309, Percent_Identity=28.8025889967638, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32566674, Length=266, Percent_Identity=29.6992481203008, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115535073, Length=288, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566672, Length=272, Percent_Identity=29.7794117647059, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561720, Length=304, Percent_Identity=26.9736842105263, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321594, Length=318, Percent_Identity=26.4150943396226, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: 2820 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005859
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 55188; Mature: 55188

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFTMDKEVLEKAVERAIENNIIIPTFAQMRDPALIPDKIKQQLKNIGLWDVNSYNLFR
CCCCCCCHHHHHHHHHHHHHCCEEEECHHHHCCCCCCCHHHHHHHHHCCCEECCCCEEEE
ITWKNEPVPKGGLYGDVNYFELPSELTGVKARIVALVGKWFPTGSHKVGATFGCLVPRLV
EEECCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
TGQFDPTTQKAVWPSTGNYCRGGAYNAQLLGCESIAILPEGMSRERFEWLSKVAGEVIGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCC
PGSESNVKEIFDKCNELKSTHDNIVIFNQFDEMGNRLWHYVVTGPAMEEVLQKIMGEKDR
CCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHEEEEEECCHHHHHHHHHHHCCHHH
LAGTVLTSGSSGTLGSGEYLKSKYPNSKLAVSEALQCPTLLYNGFGAHRIEGIGDKHVPW
CCEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCHHCCCCCCCCCCC
IHNVKNTDMVMAIDDNDAMNLIRLFNEPEGKDFLRKQGVSSSIVNNLSLLGISSIANVLS
EECCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIKFAKYYELTDKDVVMTVFTDSMELYDSRLKELQEQKGKYSEQQAAVDFEKHLMGVKTD
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FIQELSYYDKKRIHNLKYYTWIEQQGKELEELNEQWYNDEKYWGNAFEIADKIDQLINEF
HHHHHHHHHHHHHCCCHHEEEHHHHCHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHH
NKKTGLLG
HHHHCCCC
>Mature Secondary Structure
MIDFTMDKEVLEKAVERAIENNIIIPTFAQMRDPALIPDKIKQQLKNIGLWDVNSYNLFR
CCCCCCCHHHHHHHHHHHHHCCEEEECHHHHCCCCCCCHHHHHHHHHCCCEECCCCEEEE
ITWKNEPVPKGGLYGDVNYFELPSELTGVKARIVALVGKWFPTGSHKVGATFGCLVPRLV
EEECCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
TGQFDPTTQKAVWPSTGNYCRGGAYNAQLLGCESIAILPEGMSRERFEWLSKVAGEVIGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCC
PGSESNVKEIFDKCNELKSTHDNIVIFNQFDEMGNRLWHYVVTGPAMEEVLQKIMGEKDR
CCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHEEEEEECCHHHHHHHHHHHCCHHH
LAGTVLTSGSSGTLGSGEYLKSKYPNSKLAVSEALQCPTLLYNGFGAHRIEGIGDKHVPW
CCEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHCCCCCHHCCCCCCCCCCC
IHNVKNTDMVMAIDDNDAMNLIRLFNEPEGKDFLRKQGVSSSIVNNLSLLGISSIANVLS
EECCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIKFAKYYELTDKDVVMTVFTDSMELYDSRLKELQEQKGKYSEQQAAVDFEKHLMGVKTD
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FIQELSYYDKKRIHNLKYYTWIEQQGKELEELNEQWYNDEKYWGNAFEIADKIDQLINEF
HHHHHHHHHHHHHCCCHHEEEHHHHCHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHH
NKKTGLLG
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA