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The map label for this gene is appB [H]

Identifier: 160902774

GI number: 160902774

Start: 1420591

End: 1421571

Strand: Direct

Name: appB [H]

Synonym: Pmob_1327

Alternate gene names: 160902774

Gene position: 1420591-1421571 (Clockwise)

Preceding gene: 160902773

Following gene: 160902775

Centisome position: 65.48

GC content: 38.43

Gene sequence:

>981_bases
GTGATCTTGCTCAAATATATAATTAGAAGGCTTATTCTTGCTATACCTGTGTTGTTAGGAGTATCGGTTATCTCGTTTTT
TGTAATGCAGTTGGCACCTGGTGACTTTTTGGATACATATAGAATAAACCCCAATATCAGTCGCGAACAGATTCAAGAAT
TAGAAAGATTGTATGGATTGGATAAAAATCCTGTAACCCAGTATTTCTTGTGGTTAGGAAACATTATGAAGGGAGATTGG
GGTTACTCTTTTGTTTATAAAATAGATGTTTGGCAAGTGATGCTGAGAAGACTTGAAGCCACACTTTTATTGGGAGTGAC
AACTTTTATATTTACCTGGGGGATTGGTATACCTTTAGGAATAACAGCAGCGCTTCACCAATACAAATTTACTGACCAAG
CTCTTTCAACTCTTGGGTTGATAGGTCTTTCAATTCCGAACTTCTTTTTTGCGTTATTATGGTTAATGTGGTCTGCAAAT
ACTGGAATATTTCCCATCGGGGGGATGCTATCACGCGAATTTGCTAATCTTCCCTGGTATAAACAGATAGGTGATTTCTT
CTGGCATGTGGCTGGTCCTGTAGTTACATTGGGGACAGCATCTCTTGCTGGAACTATGCGTGTTATGAGAGGACAGATCT
TAGATGAGATGAACCAAGATTATGCAGAGTTTGCAAGAGCAAAGGGAATGCCTTCAGACGTTGTCATATACAAGCATACG
TTGAGAAACGCTATAAACCCTGTAATTACCTCATTGGGATTCAGTTTATCTTCGATATTGGGTGGTGCGTTGATAACGGA
ATATGTGTTTTCATGGCCAGGTTTAGGAACTTTGATGAGAGATGCGATCTTCCAGCAAGATATTTATTTAGTAATGGCTA
ATTTGTTTTTGCAAGGTATTCTATTAATTACTGGTAATTTGATCGCTGATATCTTACTTGCTGCATCTGATCCTCGTGTC
AGATTAAGAATGAGTGCTTAA

Upstream 100 bases:

>100_bases
AAAATTGAGTACGCCTGGAAAGAACAGTAATTGTTAGGTTTATTAAAAAAGGGCGGAAGGGAAACCTTCTGCCTTTTTAA
AATCATAGTAGGGAGGCTTC

Downstream 100 bases:

>100_bases
ATTGGAGGGATTTTTAAGTGAGAAAAAAGCAGAAGGACAATTTGAAGAACACACCCCAAAACACACAAAACGATGAAGAA
CTTTTTGAGCGAGAATTCAT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MILLKYIIRRLILAIPVLLGVSVISFFVMQLAPGDFLDTYRINPNISREQIQELERLYGLDKNPVTQYFLWLGNIMKGDW
GYSFVYKIDVWQVMLRRLEATLLLGVTTFIFTWGIGIPLGITAALHQYKFTDQALSTLGLIGLSIPNFFFALLWLMWSAN
TGIFPIGGMLSREFANLPWYKQIGDFFWHVAGPVVTLGTASLAGTMRVMRGQILDEMNQDYAEFARAKGMPSDVVIYKHT
LRNAINPVITSLGFSLSSILGGALITEYVFSWPGLGTLMRDAIFQQDIYLVMANLFLQGILLITGNLIADILLAASDPRV
RLRMSA

Sequences:

>Translated_326_residues
MILLKYIIRRLILAIPVLLGVSVISFFVMQLAPGDFLDTYRINPNISREQIQELERLYGLDKNPVTQYFLWLGNIMKGDW
GYSFVYKIDVWQVMLRRLEATLLLGVTTFIFTWGIGIPLGITAALHQYKFTDQALSTLGLIGLSIPNFFFALLWLMWSAN
TGIFPIGGMLSREFANLPWYKQIGDFFWHVAGPVVTLGTASLAGTMRVMRGQILDEMNQDYAEFARAKGMPSDVVIYKHT
LRNAINPVITSLGFSLSSILGGALITEYVFSWPGLGTLMRDAIFQQDIYLVMANLFLQGILLITGNLIADILLAASDPRV
RLRMSA
>Mature_326_residues
MILLKYIIRRLILAIPVLLGVSVISFFVMQLAPGDFLDTYRINPNISREQIQELERLYGLDKNPVTQYFLWLGNIMKGDW
GYSFVYKIDVWQVMLRRLEATLLLGVTTFIFTWGIGIPLGITAALHQYKFTDQALSTLGLIGLSIPNFFFALLWLMWSAN
TGIFPIGGMLSREFANLPWYKQIGDFFWHVAGPVVTLGTASLAGTMRVMRGQILDEMNQDYAEFARAKGMPSDVVIYKHT
LRNAINPVITSLGFSLSSILGGALITEYVFSWPGLGTLMRDAIFQQDIYLVMANLFLQGILLITGNLIADILLAASDPRV
RLRMSA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=33.7278106508876, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1789888, Length=322, Percent_Identity=33.2298136645963, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787053, Length=324, Percent_Identity=32.0987654320988, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1788504, Length=356, Percent_Identity=29.2134831460674, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=32.0872274143302, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=31.3432835820896, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787761, Length=296, Percent_Identity=30.0675675675676, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36648; Mature: 36648

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLKYIIRRLILAIPVLLGVSVISFFVMQLAPGDFLDTYRINPNISREQIQELERLYGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCC
DKNPVTQYFLWLGNIMKGDWGYSFVYKIDVWQVMLRRLEATLLLGVTTFIFTWGIGIPLG
CCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ITAALHQYKFTDQALSTLGLIGLSIPNFFFALLWLMWSANTGIFPIGGMLSREFANLPWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHCCCHH
KQIGDFFWHVAGPVVTLGTASLAGTMRVMRGQILDEMNQDYAEFARAKGMPSDVVIYKHT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHH
LRNAINPVITSLGFSLSSILGGALITEYVFSWPGLGTLMRDAIFQQDIYLVMANLFLQGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLITGNLIADILLAASDPRVRLRMSA
HHHHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MILLKYIIRRLILAIPVLLGVSVISFFVMQLAPGDFLDTYRINPNISREQIQELERLYGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCC
DKNPVTQYFLWLGNIMKGDWGYSFVYKIDVWQVMLRRLEATLLLGVTTFIFTWGIGIPLG
CCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ITAALHQYKFTDQALSTLGLIGLSIPNFFFALLWLMWSANTGIFPIGGMLSREFANLPWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHCCCHH
KQIGDFFWHVAGPVVTLGTASLAGTMRVMRGQILDEMNQDYAEFARAKGMPSDVVIYKHT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHH
LRNAINPVITSLGFSLSSILGGALITEYVFSWPGLGTLMRDAIFQQDIYLVMANLFLQGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLITGNLIADILLAASDPRVRLRMSA
HHHHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]