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The map label for this gene is ywkD [H]

Identifier: 160901974

GI number: 160901974

Start: 542684

End: 543091

Strand: Direct

Name: ywkD [H]

Synonym: Pmob_0498

Alternate gene names: 160901974

Gene position: 542684-543091 (Clockwise)

Preceding gene: 160901973

Following gene: 160901975

Centisome position: 25.01

GC content: 31.62

Gene sequence:

>408_bases
ATGGATTTTAATTTTGATCATTTAGCAATCACAGTTTCCGATTTGGAAAAATCTGTTGGATTTTACAGAGATATTATGGG
TTTTAGAGTTTTAGGAAAACTTGTTCAAGACAATGGGAATTTCGTAATTGTTTACCTTGATATGGGGGATAAAGTACTCG
AATTATTCAATTTTACAGAAAAAGGAAAATATCTAACAACTCAAAACGATAAAGACATGGGCATAAAACACTTTGCTTTT
AAAGTAAAAAGTGTCGATCAAGCCTTTAAATATCTAAGAGAAAAAGGTGTAGAATTCACAATGGAACCTAACAATGCTGT
GGGCGGCGTACGAATCGCTTTTTTCAAAGACCCTGATAACATTCTAATAGAGATAATTGAGGGAGAACTTAATTTAGAAA
CATATTAA

Upstream 100 bases:

>100_bases
ACTTCTTTACTCTTTTTCCATCCTATCAAAAAGTTTTAAATAATATTGAAGGGGAAATTAGCATAAAAAGCGCCTTTGAT
TATTTGAGGAGATGAGTATT

Downstream 100 bases:

>100_bases
GTGTAACCTTTGAGGTGAGAAAAATGGCAACGATAAGAGAAATCGCTAAAGCTTCGGGCTTCTCTATTGCAACGGTGTCT
CGAGTTCTCAGTGGAAGCGA

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MDFNFDHLAITVSDLEKSVGFYRDIMGFRVLGKLVQDNGNFVIVYLDMGDKVLELFNFTEKGKYLTTQNDKDMGIKHFAF
KVKSVDQAFKYLREKGVEFTMEPNNAVGGVRIAFFKDPDNILIEIIEGELNLETY

Sequences:

>Translated_135_residues
MDFNFDHLAITVSDLEKSVGFYRDIMGFRVLGKLVQDNGNFVIVYLDMGDKVLELFNFTEKGKYLTTQNDKDMGIKHFAF
KVKSVDQAFKYLREKGVEFTMEPNNAVGGVRIAFFKDPDNILIEIIEGELNLETY
>Mature_135_residues
MDFNFDHLAITVSDLEKSVGFYRDIMGFRVLGKLVQDNGNFVIVYLDMGDKVLELFNFTEKGKYLTTQNDKDMGIKHFAF
KVKSVDQAFKYLREKGVEFTMEPNNAVGGVRIAFFKDPDNILIEIIEGELNLETY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15535; Mature: 15535

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNFDHLAITVSDLEKSVGFYRDIMGFRVLGKLVQDNGNFVIVYLDMGDKVLELFNFTE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCC
KGKYLTTQNDKDMGIKHFAFKVKSVDQAFKYLREKGVEFTMEPNNAVGGVRIAFFKDPDN
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCC
ILIEIIEGELNLETY
EEEEEEECEEEEECC
>Mature Secondary Structure
MDFNFDHLAITVSDLEKSVGFYRDIMGFRVLGKLVQDNGNFVIVYLDMGDKVLELFNFTE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCC
KGKYLTTQNDKDMGIKHFAFKVKSVDQAFKYLREKGVEFTMEPNNAVGGVRIAFFKDPDN
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCC
ILIEIIEGELNLETY
EEEEEEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]