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The map label for this gene is aaeB [H]

Identifier: 160877523

GI number: 160877523

Start: 5224046

End: 5226118

Strand: Direct

Name: aaeB [H]

Synonym: Sbal195_4422

Alternate gene names: 160877523

Gene position: 5224046-5226118 (Clockwise)

Preceding gene: 160877522

Following gene: 160877524

Centisome position: 97.7

GC content: 50.8

Gene sequence:

>2073_bases
ATGACGCTGTTACTGAAGAGTTTATTCTTTCCAGACCGACGAACCCTCATCTTCGCGATTAAGGGCGTGATCTCGATGGC
GCTCGCCTTATATGTGGCCATGTTCTTAAATCTAGAACGGCCATATTGGGCGCTGGTGTCGGCGGTATTCCTGCAAATCC
GCCCCGAAAGTGGACTCGTGATCGAAAAGGGCTTATGCCAAATCGGCGGCACCTTAGTCGGCGCGCTCGCGGGGATTGCC
ATACTCAACTGGTTTACGCCCTATCCCGAACTCGCCTTAGGATTACTCGCCTGCTGGATAGGGCTAAATTCTGGGTTGTC
GGCCATGGTACGCCAGCAAAACTTTGTCTATGCCTTTGCTATGGCGGGCATGACCGCCTGCTTGATAGTGCTCATTGTGA
TGGCAAGCCCGAGCACGGCCGATAGCGCAAAAATATTCGATGTGGCGCAGTCGAGGATCAGCGAGATTGTTGTTGGGGCG
ATATGCGCCGTCTTGGTCAGCTCGCTACTTTGGCCGACCAAGGTAAAACATAGTCTGCAACTGCATGCTAAAAACACAAT
TAATCATACGCTTAACTATCTTGCATTAGAACTCGATTTACAGGGGGAACATGCGAGTCGCCATGAACATATCGACACGA
TTATGGAGTCAGTATCGGCGCTGAGTGACGATTCCAGTGCGGTGATTTATGAAGGCCCCGAAGGACGCGGGCAGAGCCAT
GCGGCGAACTTTCTCTGCAATAAAACCCTTTCGCTATTGGCGGCAATCCAAATATTTGGCCGGCTGCAACGCAATCATTC
CCATCTTGTTAGCGAACCACTCGCGAAATCCTTAGCCAATATGCGCAGTAGTTTTACCTTGATGGCGCAATCGAGTGATT
ACCAAGAATGCTACAAAATGGCGCGCACCTTGAGGTATCAACTCCAACAAAACCTGATGCAATACCGCGACCGCGCGCCG
CTAGAGACACGCTTACTCAAAGTTGCGATGGAATTAAGCGCCGATCTGATCATGGTGCTCAAGAGTTATAACGTGCTAAC
CAGTCATTCTGCGGTACAGCTCAGCGCGCCGCCGATGGAGTTTCACCGAGACCCATTAATAGGCGTTACCACGGGCCTGC
GCAGCATGGCGGTGTTTGTCATTGGGGCTTCACTGTGGATTGGCACAGGGTCGAGCGCGGTCCTCATGATGATCCTGCTG
CCCGTGGTCTTTTCCATCATGATGGCGCGCCAGCCATTACCGATGTTAACCACGATTTTGCGCCGCATTCTTGTCGGCAT
CACTATCGCTGTGCCCCTCACAGTGTTTTACGCTTTACCTTTACTAGCACAGAGTAGCGGCGATTTTGAAATCCTCGTTT
TAGTGCTCGCTGGGCCGTTTTTTATTGGCCTACTCGCCTTGGCGAATCGACCAACCTTGCCCTATGGGCTCGGCATTTGC
GTGCCGTTTGCTGTGTTAGTGCAGCCCAGCAACACCATTTCATTTGCGATAGAAAACACCGTCAGCAATGCCTTAGCGAT
TTTTGTTGGCGTTACTGTACTGTATTGGTTGTTTAAATTGATTACCGAACCCAGCCAGCGGTTGATGCAATATCGTCTAC
TGCAATCCATCCAAAAAGATCTGGTGCATATCGCGCAGCATGATGATCCTGAGCCTTGGTTTAACGCCCGCATGGGCGAT
CGACTGCTGCGGATCGCCAGTTACGAAAAAGGCTCGGGCAAGAGTTCGAGGGTATTTACCGATCTGGTGTTTACGGCACT
TAATCTAGGCCATGTGTCGATTCGGATGCGGCGCATGTTGCAGGGCATTTCAGATACGCACTTAAACTTAGGCTTAGAAA
ATGCACTCAACCTCTGGCAACACAATTTAGGTCAGGCATTTATCGCCTGCGCCCACGGACAAGTCGCAGAAGAGTTTAAA
ATCAGCAACGAGGCCTTATTACAAGCGCTGGCCCAATGTCCGTTACCCCACGAACAATTCACTATGATTACTGGGATGTT
TGAACGCATCACTTTAACCTTCGAACGCACAGCCCACAGTATCGCCGAGCAGAAAAACACCTCAGAAAAATAG

Upstream 100 bases:

>100_bases
GTATTCCGGTCGATATTGAGCTAGATAGCATTCCTAAGGACATAGAGCTGAGCGTCGGCATGACAGTTTCCATCCAGCTA
CAGACTGACAAATAGTCATT

Downstream 100 bases:

>100_bases
TCAGTTCTCAAACTATTTTCCACCCCAAAAGCCACTCTTTTACTGCCACCAAAACCATTTAAATCTAATAGAAGCTTGAT
ATTTGGCCGATAAAATGCCT

Product: fusaric acid resistance protein region

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MTLLLKSLFFPDRRTLIFAIKGVISMALALYVAMFLNLERPYWALVSAVFLQIRPESGLVIEKGLCQIGGTLVGALAGIA
ILNWFTPYPELALGLLACWIGLNSGLSAMVRQQNFVYAFAMAGMTACLIVLIVMASPSTADSAKIFDVAQSRISEIVVGA
ICAVLVSSLLWPTKVKHSLQLHAKNTINHTLNYLALELDLQGEHASRHEHIDTIMESVSALSDDSSAVIYEGPEGRGQSH
AANFLCNKTLSLLAAIQIFGRLQRNHSHLVSEPLAKSLANMRSSFTLMAQSSDYQECYKMARTLRYQLQQNLMQYRDRAP
LETRLLKVAMELSADLIMVLKSYNVLTSHSAVQLSAPPMEFHRDPLIGVTTGLRSMAVFVIGASLWIGTGSSAVLMMILL
PVVFSIMMARQPLPMLTTILRRILVGITIAVPLTVFYALPLLAQSSGDFEILVLVLAGPFFIGLLALANRPTLPYGLGIC
VPFAVLVQPSNTISFAIENTVSNALAIFVGVTVLYWLFKLITEPSQRLMQYRLLQSIQKDLVHIAQHDDPEPWFNARMGD
RLLRIASYEKGSGKSSRVFTDLVFTALNLGHVSIRMRRMLQGISDTHLNLGLENALNLWQHNLGQAFIACAHGQVAEEFK
ISNEALLQALAQCPLPHEQFTMITGMFERITLTFERTAHSIAEQKNTSEK

Sequences:

>Translated_690_residues
MTLLLKSLFFPDRRTLIFAIKGVISMALALYVAMFLNLERPYWALVSAVFLQIRPESGLVIEKGLCQIGGTLVGALAGIA
ILNWFTPYPELALGLLACWIGLNSGLSAMVRQQNFVYAFAMAGMTACLIVLIVMASPSTADSAKIFDVAQSRISEIVVGA
ICAVLVSSLLWPTKVKHSLQLHAKNTINHTLNYLALELDLQGEHASRHEHIDTIMESVSALSDDSSAVIYEGPEGRGQSH
AANFLCNKTLSLLAAIQIFGRLQRNHSHLVSEPLAKSLANMRSSFTLMAQSSDYQECYKMARTLRYQLQQNLMQYRDRAP
LETRLLKVAMELSADLIMVLKSYNVLTSHSAVQLSAPPMEFHRDPLIGVTTGLRSMAVFVIGASLWIGTGSSAVLMMILL
PVVFSIMMARQPLPMLTTILRRILVGITIAVPLTVFYALPLLAQSSGDFEILVLVLAGPFFIGLLALANRPTLPYGLGIC
VPFAVLVQPSNTISFAIENTVSNALAIFVGVTVLYWLFKLITEPSQRLMQYRLLQSIQKDLVHIAQHDDPEPWFNARMGD
RLLRIASYEKGSGKSSRVFTDLVFTALNLGHVSIRMRRMLQGISDTHLNLGLENALNLWQHNLGQAFIACAHGQVAEEFK
ISNEALLQALAQCPLPHEQFTMITGMFERITLTFERTAHSIAEQKNTSEK
>Mature_689_residues
TLLLKSLFFPDRRTLIFAIKGVISMALALYVAMFLNLERPYWALVSAVFLQIRPESGLVIEKGLCQIGGTLVGALAGIAI
LNWFTPYPELALGLLACWIGLNSGLSAMVRQQNFVYAFAMAGMTACLIVLIVMASPSTADSAKIFDVAQSRISEIVVGAI
CAVLVSSLLWPTKVKHSLQLHAKNTINHTLNYLALELDLQGEHASRHEHIDTIMESVSALSDDSSAVIYEGPEGRGQSHA
ANFLCNKTLSLLAAIQIFGRLQRNHSHLVSEPLAKSLANMRSSFTLMAQSSDYQECYKMARTLRYQLQQNLMQYRDRAPL
ETRLLKVAMELSADLIMVLKSYNVLTSHSAVQLSAPPMEFHRDPLIGVTTGLRSMAVFVIGASLWIGTGSSAVLMMILLP
VVFSIMMARQPLPMLTTILRRILVGITIAVPLTVFYALPLLAQSSGDFEILVLVLAGPFFIGLLALANRPTLPYGLGICV
PFAVLVQPSNTISFAIENTVSNALAIFVGVTVLYWLFKLITEPSQRLMQYRLLQSIQKDLVHIAQHDDPEPWFNARMGDR
LLRIASYEKGSGKSSRVFTDLVFTALNLGHVSIRMRRMLQGISDTHLNLGLENALNLWQHNLGQAFIACAHGQVAEEFKI
SNEALLQALAQCPLPHEQFTMITGMFERITLTFERTAHSIAEQKNTSEK

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=530, Percent_Identity=22.6415094339623, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1787933, Length=533, Percent_Identity=23.2645403377111, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 76171; Mature: 76039

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLLKSLFFPDRRTLIFAIKGVISMALALYVAMFLNLERPYWALVSAVFLQIRPESGLV
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCE
IEKGLCQIGGTLVGALAGIAILNWFTPYPELALGLLACWIGLNSGLSAMVRQQNFVYAFA
ECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
MAGMTACLIVLIVMASPSTADSAKIFDVAQSRISEIVVGAICAVLVSSLLWPTKVKHSLQ
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LHAKNTINHTLNYLALELDLQGEHASRHEHIDTIMESVSALSDDSSAVIYEGPEGRGQSH
HHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
AANFLCNKTLSLLAAIQIFGRLQRNHSHLVSEPLAKSLANMRSSFTLMAQSSDYQECYKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHH
ARTLRYQLQQNLMQYRDRAPLETRLLKVAMELSADLIMVLKSYNVLTSHSAVQLSAPPME
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEECCCCHH
FHRDPLIGVTTGLRSMAVFVIGASLWIGTGSSAVLMMILLPVVFSIMMARQPLPMLTTIL
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RRILVGITIAVPLTVFYALPLLAQSSGDFEILVLVLAGPFFIGLLALANRPTLPYGLGIC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
VPFAVLVQPSNTISFAIENTVSNALAIFVGVTVLYWLFKLITEPSQRLMQYRLLQSIQKD
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVHIAQHDDPEPWFNARMGDRLLRIASYEKGSGKSSRVFTDLVFTALNLGHVSIRMRRML
HHHHHCCCCCCCHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
QGISDTHLNLGLENALNLWQHNLGQAFIACAHGQVAEEFKISNEALLQALAQCPLPHEQF
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCHHHH
TMITGMFERITLTFERTAHSIAEQKNTSEK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLLLKSLFFPDRRTLIFAIKGVISMALALYVAMFLNLERPYWALVSAVFLQIRPESGLV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCE
IEKGLCQIGGTLVGALAGIAILNWFTPYPELALGLLACWIGLNSGLSAMVRQQNFVYAFA
ECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
MAGMTACLIVLIVMASPSTADSAKIFDVAQSRISEIVVGAICAVLVSSLLWPTKVKHSLQ
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LHAKNTINHTLNYLALELDLQGEHASRHEHIDTIMESVSALSDDSSAVIYEGPEGRGQSH
HHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
AANFLCNKTLSLLAAIQIFGRLQRNHSHLVSEPLAKSLANMRSSFTLMAQSSDYQECYKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHH
ARTLRYQLQQNLMQYRDRAPLETRLLKVAMELSADLIMVLKSYNVLTSHSAVQLSAPPME
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEECCCCHH
FHRDPLIGVTTGLRSMAVFVIGASLWIGTGSSAVLMMILLPVVFSIMMARQPLPMLTTIL
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RRILVGITIAVPLTVFYALPLLAQSSGDFEILVLVLAGPFFIGLLALANRPTLPYGLGIC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
VPFAVLVQPSNTISFAIENTVSNALAIFVGVTVLYWLFKLITEPSQRLMQYRLLQSIQKD
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVHIAQHDDPEPWFNARMGDRLLRIASYEKGSGKSSRVFTDLVFTALNLGHVSIRMRRML
HHHHHCCCCCCCHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
QGISDTHLNLGLENALNLWQHNLGQAFIACAHGQVAEEFKISNEALLQALAQCPLPHEQF
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCHHHH
TMITGMFERITLTFERTAHSIAEQKNTSEK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA