Click here to switch to the map view.

The map label for this gene is pepQ [H]

Identifier: 160876344

GI number: 160876344

Start: 3808112

End: 3809899

Strand: Direct

Name: pepQ [H]

Synonym: Sbal195_3238

Alternate gene names: 160876344

Gene position: 3808112-3809899 (Clockwise)

Preceding gene: 160876341

Following gene: 160876346

Centisome position: 71.22

GC content: 49.89

Gene sequence:

>1788_bases
ATGTCACATTCAATTGCCAGCCGCCTCGGTGCCATTCGCAGCGAATTATCTTCCGCCAATCTCGATGCTTTTATCATTCC
CCGCGCCGACGAGTATCTGGGCGAATATGTGCCAGAACATAACGAACGTTTGTACTGGGCAACCAACTTCACTGGCTCGG
CAGGTATGGCTATCGTATTGAAAGATAAAGCCGCTATCTTTACCGACGGCCGTTATACGGTTCAAGTTCGTCTGCAAGTG
GATGCCGCACTTTTCAGCTATGAAAGCCTGACAGACACACCGCAAATTGAATGGTTATGTGACACGCTACCAGCGGGGTC
ACGCGTTGGCTTCGATGCACGCTTGCATACTTTAGCTTGGTTTGAAAATGCCAAAGCGACCTTAAACAAAGCCCAAATCG
AATTAGTGGTGGTTGAGCAAAATCCTATCGATTTATATTGGCAGGATCGCCCCGCACCATCGAGTGCGCCAATCACGTTA
TTCAGTAACGAGAGTGCCGGTAAAACCAGTCTACAAAAACGCATTGAAATTGGCGCCTTAGTAAAAAAAGCCGGTGCTGA
TGTCGCGTTGATCGCCGCCTTAGATTCTTTCTGCTGGTTGTTAAATATTCGCGGTAACGATGTGCCGCGTCTGCCCGTTG
TGCTCGGCAGTGCCCTACTCCACGCTAATGGCGATATGCAGCTGTTTACCGATTTAAGCAAACTCCCTGACGGCATCGAG
GAGCATGTCGGTGCAGGCGTTAGCTTTAAAAGTGAAGCGTCCCTCGCCGATACGCTGGCGAGTTTATCAGGCGTTAAACT
GCTCGCCGATCCAAACTCAGCTAACGCTTGGGCGCAAAATCTCGCCCGTGAAGCGGGGGCTAAATTGATTGCTGGAATTG
ATCCCGTTTCTTTACCTAAAGCACAGAAAAATCCTTCAGAACTTGCCGGAATGCGCGCTTGTCACATTCGTGATGGCGTT
GCAGTGAGCCGCTTCCTTGCATGGTTAGATGCCGAAGTTGCCGCCAAGCGTATGCACGATGAAGCCACGCTTGCCGATAA
ATTAGAAAGCTTCCGCCTGCAAGATGAGCGCTATCGCGAGCCAAGTTTCGACACGATTTCAGCAGCGGGCCCCAATGCCG
CCATGTGCCATTACAATCATAACAATGGCACACCTGCGATGATGACGATGGACAGCATCTACTTAGTGGATTCTGGCGCG
CAATATATCGATGGCACTACAGATGTGACCCGTACTATTGCGATTGGCAAAGTGACCGATGAACATAAAAAAATGGTCAC
GCTGGTACTAAAAGGCCATATCGCACTGGACCAAGCTCGCTTCCCTAAAGGCACCTCAGGCCAGCAGCTCGATGCATTCG
CCCGCCAATATTTATGGCAGCATGGTTTTGATTACGACCACGGCACAGGCCATGGCGTGGGTCACTTTTTAAGTGTGCAC
GAAGGTCCACAGCGCATAGGTAAAAATGTCAACGGTATCGCACTGATGCCAGGCATGGTGCTTTCCAACGAGCCGGGTTA
TTACCGTGCGGAGTGTTTTGGTATTCGCTTAGAAAACTTAGTCGTAGTGCAACACTGCGAAGCACTGAAAGGGATAGAGC
GTGAGATGTATGAGTTCGATGCACTGACGATGATCCCTATGGATGCACGCCTTATCGATAAGAGCCTGTTAACGCAAGGG
GAAATCGACTGGTTCAATGCTTACCATCAGCAAGTATTCAATACTCTTTCCCCGCTGATGTCGGGTGATGAACTCGCTTG
GTTAACGCAAGTGACTAAAGCGATTTAA

Upstream 100 bases:

>100_bases
ATCCGAGCTGGTTAGAACTCAAATAAACATAGACCTACTTATCCTTAGGCAAGCTTTGCCTACCGACTAGCACAGCGTGC
AAGTCTCACTTGGAGCCCAT

Downstream 100 bases:

>100_bases
GTCGTCATTTAAATCATCTTCTAAATCCGTTATATGCTACAAAATAAAGCGCCCAAGACTATGAGCCTTGGGCGTTTTTT
TAGCACTGCTTCTGTACTTT

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MSHSIASRLGAIRSELSSANLDAFIIPRADEYLGEYVPEHNERLYWATNFTGSAGMAIVLKDKAAIFTDGRYTVQVRLQV
DAALFSYESLTDTPQIEWLCDTLPAGSRVGFDARLHTLAWFENAKATLNKAQIELVVVEQNPIDLYWQDRPAPSSAPITL
FSNESAGKTSLQKRIEIGALVKKAGADVALIAALDSFCWLLNIRGNDVPRLPVVLGSALLHANGDMQLFTDLSKLPDGIE
EHVGAGVSFKSEASLADTLASLSGVKLLADPNSANAWAQNLAREAGAKLIAGIDPVSLPKAQKNPSELAGMRACHIRDGV
AVSRFLAWLDAEVAAKRMHDEATLADKLESFRLQDERYREPSFDTISAAGPNAAMCHYNHNNGTPAMMTMDSIYLVDSGA
QYIDGTTDVTRTIAIGKVTDEHKKMVTLVLKGHIALDQARFPKGTSGQQLDAFARQYLWQHGFDYDHGTGHGVGHFLSVH
EGPQRIGKNVNGIALMPGMVLSNEPGYYRAECFGIRLENLVVVQHCEALKGIEREMYEFDALTMIPMDARLIDKSLLTQG
EIDWFNAYHQQVFNTLSPLMSGDELAWLTQVTKAI

Sequences:

>Translated_595_residues
MSHSIASRLGAIRSELSSANLDAFIIPRADEYLGEYVPEHNERLYWATNFTGSAGMAIVLKDKAAIFTDGRYTVQVRLQV
DAALFSYESLTDTPQIEWLCDTLPAGSRVGFDARLHTLAWFENAKATLNKAQIELVVVEQNPIDLYWQDRPAPSSAPITL
FSNESAGKTSLQKRIEIGALVKKAGADVALIAALDSFCWLLNIRGNDVPRLPVVLGSALLHANGDMQLFTDLSKLPDGIE
EHVGAGVSFKSEASLADTLASLSGVKLLADPNSANAWAQNLAREAGAKLIAGIDPVSLPKAQKNPSELAGMRACHIRDGV
AVSRFLAWLDAEVAAKRMHDEATLADKLESFRLQDERYREPSFDTISAAGPNAAMCHYNHNNGTPAMMTMDSIYLVDSGA
QYIDGTTDVTRTIAIGKVTDEHKKMVTLVLKGHIALDQARFPKGTSGQQLDAFARQYLWQHGFDYDHGTGHGVGHFLSVH
EGPQRIGKNVNGIALMPGMVLSNEPGYYRAECFGIRLENLVVVQHCEALKGIEREMYEFDALTMIPMDARLIDKSLLTQG
EIDWFNAYHQQVFNTLSPLMSGDELAWLTQVTKAI
>Mature_594_residues
SHSIASRLGAIRSELSSANLDAFIIPRADEYLGEYVPEHNERLYWATNFTGSAGMAIVLKDKAAIFTDGRYTVQVRLQVD
AALFSYESLTDTPQIEWLCDTLPAGSRVGFDARLHTLAWFENAKATLNKAQIELVVVEQNPIDLYWQDRPAPSSAPITLF
SNESAGKTSLQKRIEIGALVKKAGADVALIAALDSFCWLLNIRGNDVPRLPVVLGSALLHANGDMQLFTDLSKLPDGIEE
HVGAGVSFKSEASLADTLASLSGVKLLADPNSANAWAQNLAREAGAKLIAGIDPVSLPKAQKNPSELAGMRACHIRDGVA
VSRFLAWLDAEVAAKRMHDEATLADKLESFRLQDERYREPSFDTISAAGPNAAMCHYNHNNGTPAMMTMDSIYLVDSGAQ
YIDGTTDVTRTIAIGKVTDEHKKMVTLVLKGHIALDQARFPKGTSGQQLDAFARQYLWQHGFDYDHGTGHGVGHFLSVHE
GPQRIGKNVNGIALMPGMVLSNEPGYYRAECFGIRLENLVVVQHCEALKGIEREMYEFDALTMIPMDARLIDKSLLTQGE
IDWFNAYHQQVFNTLSPLMSGDELAWLTQVTKAI

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI93141226, Length=604, Percent_Identity=35.5960264900662, Blast_Score=359, Evalue=4e-99,
Organism=Homo sapiens, GI264681563, Length=603, Percent_Identity=36.318407960199, Blast_Score=355, Evalue=6e-98,
Organism=Homo sapiens, GI264681565, Length=603, Percent_Identity=34.6600331674959, Blast_Score=322, Evalue=5e-88,
Organism=Escherichia coli, GI1788728, Length=343, Percent_Identity=26.8221574344023, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17509539, Length=599, Percent_Identity=34.2237061769616, Blast_Score=332, Evalue=4e-91,
Organism=Caenorhabditis elegans, GI25149105, Length=595, Percent_Identity=29.9159663865546, Blast_Score=262, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322999, Length=651, Percent_Identity=31.4900153609831, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI17137632, Length=599, Percent_Identity=39.0651085141903, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI161078230, Length=598, Percent_Identity=29.4314381270903, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI21357287, Length=598, Percent_Identity=29.4314381270903, Blast_Score=251, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 65216; Mature: 65085

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSIASRLGAIRSELSSANLDAFIIPRADEYLGEYVPEHNERLYWATNFTGSAGMAIVL
CCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEE
KDKAAIFTDGRYTVQVRLQVDAALFSYESLTDTPQIEWLCDTLPAGSRVGFDARLHTLAW
ECCEEEEECCEEEEEEEEEEEEHHHHHHHCCCCCCCEEHCCCCCCCCCCCCCHHHHHHHH
FENAKATLNKAQIELVVVEQNPIDLYWQDRPAPSSAPITLFSNESAGKTSLQKRIEIGAL
HHCCHHHCCEEEEEEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
VKKAGADVALIAALDSFCWLLNIRGNDVPRLPVVLGSALLHANGDMQLFTDLSKLPDGIE
HHHCCCCEEEHHHHHCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
EHVGAGVSFKSEASLADTLASLSGVKLLADPNSANAWAQNLAREAGAKLIAGIDPVSLPK
HHHCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCCCCC
AQKNPSELAGMRACHIRDGVAVSRFLAWLDAEVAAKRMHDEATLADKLESFRLQDERYRE
CCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
PSFDTISAAGPNAAMCHYNHNNGTPAMMTMDSIYLVDSGAQYIDGTTDVTRTIAIGKVTD
CCCCEEECCCCCCEEEEEECCCCCCEEEEEEEEEEEECCCHHCCCCCHHEEEEEEECCCH
EHKKMVTLVLKGHIALDQARFPKGTSGQQLDAFARQYLWQHGFDYDHGTGHGVGHFLSVH
HHHHEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECC
EGPQRIGKNVNGIALMPGMVLSNEPGYYRAECFGIRLENLVVVQHCEALKGIEREMYEFD
CCHHHHCCCCCCEEECCCEEECCCCCCEEEEEEEEEHHHEHHHHHHHHHHHHHHHHHHHC
ALTMIPMDARLIDKSLLTQGEIDWFNAYHQQVFNTLSPLMSGDELAWLTQVTKAI
CEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SHSIASRLGAIRSELSSANLDAFIIPRADEYLGEYVPEHNERLYWATNFTGSAGMAIVL
CCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEE
KDKAAIFTDGRYTVQVRLQVDAALFSYESLTDTPQIEWLCDTLPAGSRVGFDARLHTLAW
ECCEEEEECCEEEEEEEEEEEEHHHHHHHCCCCCCCEEHCCCCCCCCCCCCCHHHHHHHH
FENAKATLNKAQIELVVVEQNPIDLYWQDRPAPSSAPITLFSNESAGKTSLQKRIEIGAL
HHCCHHHCCEEEEEEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
VKKAGADVALIAALDSFCWLLNIRGNDVPRLPVVLGSALLHANGDMQLFTDLSKLPDGIE
HHHCCCCEEEHHHHHCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
EHVGAGVSFKSEASLADTLASLSGVKLLADPNSANAWAQNLAREAGAKLIAGIDPVSLPK
HHHCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCCCCC
AQKNPSELAGMRACHIRDGVAVSRFLAWLDAEVAAKRMHDEATLADKLESFRLQDERYRE
CCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
PSFDTISAAGPNAAMCHYNHNNGTPAMMTMDSIYLVDSGAQYIDGTTDVTRTIAIGKVTD
CCCCEEECCCCCCEEEEEECCCCCCEEEEEEEEEEEECCCHHCCCCCHHEEEEEEECCCH
EHKKMVTLVLKGHIALDQARFPKGTSGQQLDAFARQYLWQHGFDYDHGTGHGVGHFLSVH
HHHHEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECC
EGPQRIGKNVNGIALMPGMVLSNEPGYYRAECFGIRLENLVVVQHCEALKGIEREMYEFD
CCHHHHCCCCCCEEECCCEEECCCCCCEEEEEEEEEHHHEHHHHHHHHHHHHHHHHHHHC
ALTMIPMDARLIDKSLLTQGEIDWFNAYHQQVFNTLSPLMSGDELAWLTQVTKAI
CEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]