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The map label for this gene is aer [H]

Identifier: 160876346

GI number: 160876346

Start: 3811916

End: 3813517

Strand: Direct

Name: aer [H]

Synonym: Sbal195_3240

Alternate gene names: 160876346

Gene position: 3811916-3813517 (Clockwise)

Preceding gene: 160876344

Following gene: 160876347

Centisome position: 71.29

GC content: 50.37

Gene sequence:

>1602_bases
ATGAACCATATCGGCCCTGAATGGACACACAAAATGAGTCAGAGTAACGCGTCTGCCAACAGAACACTGAATACACAGAG
ATCAGATCAAGAAATTCGCTTAACACCACAGGACGAACTCATTTCCACCACCGACACTCGCGGTGTTATCACTTACGTTA
ATGCCCGTTTTGCCGAAGTCTCAGGCTATAGCGCCCAAGAGTTAGTCGGCAGTGCCCACAATATGGTTCGTCATCCCGAT
ATGCCGAGCGCCGCCTTTAAAGAAATGTGGGAAAAGCTTAAGTCGGGCCAATCTTGGCGCGGCATAGTGAAAAACCGCTG
CAAAAATGGTGGCTTCTATTGGGTCGATGCCTTTGTCTCGCCATTGTTTGAAAACGGCACCATTATCGGTTATCAATCGG
TGCGTATTCAGCCTCAGGCCGCCTACGTCAGCAAAGCAAATGAGATATACCAAAGACTTAAACTGGATAAATCCATTTCT
AAGCCCTTAAGCTTAATGCAGAAACGTATCCTCTCGGCGGTTGTCGCCTCGACCGGCCTGCTGATCGCAGGCTACTTTTG
GGGCTGGGGCGTGATTATCGCTGGGGCGGTTTTGATGAGTTTAAACTTGGCTATTTTCTACGATGAGGCCTTTCGCATTC
CCGCTAAACTGATTGAAATGCAAACCAAATACGACTCTATCAGTCGTTACATCTACTCGGGTGCCGATACGTCTTCTATC
CTCGACTTCCAGCTCATCATGCTGCAGGCCAAAATGAATGGCGTACTGGGGCGCACTCAAGATCAAGCCAATCAATTGCA
CGCAATTGCCGATCAATTAGTGGTCGCGACCGAGCAAACCTATGTCAGCCTAGATCAAGAGAAAAGTCAGTTAGAACAGC
TCTCTGGCGCGATGGAAGAAATGAGTTCAACCATCACAGAAGTGGCGCAGAATACCCATCTCACGTCCACCAGCATCAAT
ACCGCCTACGATCTCTGCCTTAAAAGCAGCGCCAATATGAAGGCCAACACTCAAAAAGTGGAACAACTGGCCAAGTCTGT
TGCCGATGCCGCTAACAATGCCCATCAATTGAATAAAGAAGCCGAGCAAGTTGCTAATGCGATGGGCGAAATTGACTCCA
TCGCCGAGCAAACCAATCTTCTCGCCCTCAATGCGGCCATTGAAGCTGCCCGTGCGGGTGAACAAGGCCGTGGGTTTGCC
GTGGTCGCCGATGAAGTGCGCGCGCTGTCGAGCCGAACCCAACTGTCGACCAACAGTATTTCAAAAAGTGTCGATAAGAT
GTTCACTATGCTCAACGCATGGGCCAAAGAAATGGAACAAAGCCGCCAACACGCGGAGCGCTGCGCTAGCGACATCCAAC
TGTCCGCCGACAATGTGAATACCCTTTACCAAGAAGTGAGTGATATCCACACCTTTGCCCAGCAAAATGCGGTCGCAGCG
GATCAACAGCGCCAAGTGGTCAACGAGATTGCCAGCAACATACACTCCATCACCCATTCAAGCGCAGAGAACTTGGCCGC
GACCCATCTGATTGGTGATGCCGCCCATCTGCTTAAGCATAATGCCGAGAAAGCCCTCGGCTTGAGACGCACTTTCGGTT
AG

Upstream 100 bases:

>100_bases
TATACCCATACAAAAATGATAGTCTTATCACATAACAAGCTTACCCCAATGAGAGTAAGCGCAAGAAAATTAGCGCCTAA
CACCGCGCCCCTGAACCCCA

Downstream 100 bases:

>100_bases
TCATAAGCAAGATATAAAATGCCGCAGCCAAAACTGCGGCATTTTTCTATCGCGTTCATTTAGCCCATTCTTTGCGCCAG
CCGTCACTCAACCTTAAATC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MNHIGPEWTHKMSQSNASANRTLNTQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGSAHNMVRHPD
MPSAAFKEMWEKLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGYQSVRIQPQAAYVSKANEIYQRLKLDKSIS
KPLSLMQKRILSAVVASTGLLIAGYFWGWGVIIAGAVLMSLNLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSI
LDFQLIMLQAKMNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQNTHLTSTSIN
TAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFA
VVADEVRALSSRTQLSTNSISKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAA
DQQRQVVNEIASNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG

Sequences:

>Translated_533_residues
MNHIGPEWTHKMSQSNASANRTLNTQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGSAHNMVRHPD
MPSAAFKEMWEKLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGYQSVRIQPQAAYVSKANEIYQRLKLDKSIS
KPLSLMQKRILSAVVASTGLLIAGYFWGWGVIIAGAVLMSLNLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSI
LDFQLIMLQAKMNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQNTHLTSTSIN
TAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFA
VVADEVRALSSRTQLSTNSISKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAA
DQQRQVVNEIASNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG
>Mature_533_residues
MNHIGPEWTHKMSQSNASANRTLNTQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEVSGYSAQELVGSAHNMVRHPD
MPSAAFKEMWEKLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGYQSVRIQPQAAYVSKANEIYQRLKLDKSIS
KPLSLMQKRILSAVVASTGLLIAGYFWGWGVIIAGAVLMSLNLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSI
LDFQLIMLQAKMNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEEMSSTITEVAQNTHLTSTSIN
TAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKEAEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFA
VVADEVRALSSRTQLSTNSISKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAA
DQQRQVVNEIASNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=501, Percent_Identity=29.7405189620758, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI2367378, Length=227, Percent_Identity=31.2775330396476, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788195, Length=220, Percent_Identity=28.1818181818182, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787690, Length=220, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788194, Length=169, Percent_Identity=31.3609467455621, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 58656; Mature: 58656

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIGPEWTHKMSQSNASANRTLNTQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEV
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEEEECHHHHHC
SGYSAQELVGSAHNMVRHPDMPSAAFKEMWEKLKSGQSWRGIVKNRCKNGGFYWVDAFVS
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHH
PLFENGTIIGYQSVRIQPQAAYVSKANEIYQRLKLDKSISKPLSLMQKRILSAVVASTGL
HHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LIAGYFWGWGVIIAGAVLMSLNLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSI
HHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LDFQLIMLQAKMNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSSTITEVAQNTHLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKE
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQLSTNSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
SKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHCCHHH
DQQRQVVNEIASNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure
MNHIGPEWTHKMSQSNASANRTLNTQRSDQEIRLTPQDELISTTDTRGVITYVNARFAEV
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEEEECHHHHHC
SGYSAQELVGSAHNMVRHPDMPSAAFKEMWEKLKSGQSWRGIVKNRCKNGGFYWVDAFVS
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHH
PLFENGTIIGYQSVRIQPQAAYVSKANEIYQRLKLDKSISKPLSLMQKRILSAVVASTGL
HHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LIAGYFWGWGVIIAGAVLMSLNLAIFYDEAFRIPAKLIEMQTKYDSISRYIYSGADTSSI
HHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LDFQLIMLQAKMNGVLGRTQDQANQLHAIADQLVVATEQTYVSLDQEKSQLEQLSGAMEE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSSTITEVAQNTHLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKE
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AEQVANAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQLSTNSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
SKSVDKMFTMLNAWAKEMEQSRQHAERCASDIQLSADNVNTLYQEVSDIHTFAQQNAVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHCCHHH
DQQRQVVNEIASNIHSITHSSAENLAATHLIGDAAHLLKHNAEKALGLRRTFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]