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The map label for this gene is gph [C]

Identifier: 160875518

GI number: 160875518

Start: 2840584

End: 2841255

Strand: Direct

Name: gph [C]

Synonym: Sbal195_2406

Alternate gene names: 160875518

Gene position: 2840584-2841255 (Clockwise)

Preceding gene: 160875517

Following gene: 160875519

Centisome position: 53.12

GC content: 55.21

Gene sequence:

>672_bases
ATGAGTCTGGCACAGATCCAAGGCGTACTGTTCGATCTCGACGGCACCTTAGCCGATACCGCGCCGGATCTGGTGCAGGC
CCTTAATTTAAGTCTTCAGGACGTCGGCATCGCCGCGCAGCCGTTAGCGGCCATGCGCTACGCCGCATCCCACGGCAGTT
TTGCCTTAGTCGATGCGGCGATCCCCAATGCAGCGGATGATCTTCGTACTCAAGTTCAGCAAGGGCTGCTCGCCCACTAT
CAGCGCATTAATGGCGATCACTGTGCGCTATTCACAGGCATTGCAGCATTACTCGACTGGCTCGAGTTAACGCAGCTGCC
GTTTGGGGTGATCACCAACAAGCCAGCCCGCTTTACCCGTCCCTTATTGCGAAAACTGAATTTACACTTACGTATGCCCG
TTATCATCAGTGGCGATTCAACCAAACACCCAAAACCCCACACAGCACCTATGTTGTTAGGGGCTCAGCAACTGAACTGC
GCTCCAGAGCACATTTTGTATCTTGGGGATGCCGAGCGGGATTTGTTAGCAGCTAAGGCGGCGGGCATGTTAGGCGGCGT
TGCCCTATGGGGTTATCTGGGTGTCAACGACAAGCCATCGCAATGGCCAGCTCACGCACACTTTGCCAGCCCAACTGAGC
TACATCAGGCATTAGTCGACGCATTGGCCTAG

Upstream 100 bases:

>100_bases
GATGCATTAGGCATCAGCTACAACCCGCTGACGGGCATTTTTAAATACACGCCTAAAGTTGATGTCAATTACATGATCGC
AACGCGTAAGGTTGATTAAT

Downstream 100 bases:

>100_bases
AAAAACTCGCTAATAAAACGGCTAACAGACGTCACCATGACACTCAAAGATAAACCTTTTGCTAAAGCCAATATGCAGAC
ACACATAAGTGTGTTTGCCT

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSLAQIQGVLFDLDGTLADTAPDLVQALNLSLQDVGIAAQPLAAMRYAASHGSFALVDAAIPNAADDLRTQVQQGLLAHY
QRINGDHCALFTGIAALLDWLELTQLPFGVITNKPARFTRPLLRKLNLHLRMPVIISGDSTKHPKPHTAPMLLGAQQLNC
APEHILYLGDAERDLLAAKAAGMLGGVALWGYLGVNDKPSQWPAHAHFASPTELHQALVDALA

Sequences:

>Translated_223_residues
MSLAQIQGVLFDLDGTLADTAPDLVQALNLSLQDVGIAAQPLAAMRYAASHGSFALVDAAIPNAADDLRTQVQQGLLAHY
QRINGDHCALFTGIAALLDWLELTQLPFGVITNKPARFTRPLLRKLNLHLRMPVIISGDSTKHPKPHTAPMLLGAQQLNC
APEHILYLGDAERDLLAAKAAGMLGGVALWGYLGVNDKPSQWPAHAHFASPTELHQALVDALA
>Mature_222_residues
SLAQIQGVLFDLDGTLADTAPDLVQALNLSLQDVGIAAQPLAAMRYAASHGSFALVDAAIPNAADDLRTQVQQGLLAHYQ
RINGDHCALFTGIAALLDWLELTQLPFGVITNKPARFTRPLLRKLNLHLRMPVIISGDSTKHPKPHTAPMLLGAQQLNCA
PEHILYLGDAERDLLAAKAAGMLGGVALWGYLGVNDKPSQWPAHAHFASPTELHQALVDALA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=242, Percent_Identity=29.3388429752066, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23865; Mature: 23734

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAQIQGVLFDLDGTLADTAPDLVQALNLSLQDVGIAAQPLAAMRYAASHGSFALVDAA
CCHHHHHHEEEECCCCCCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCEEEEECC
IPNAADDLRTQVQQGLLAHYQRINGDHCALFTGIAALLDWLELTQLPFGVITNKPARFTR
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHH
PLLRKLNLHLRMPVIISGDSTKHPKPHTAPMLLGAQQLNCAPEHILYLGDAERDLLAAKA
HHHHHCCCEEECCEEEECCCCCCCCCCCCHHHHCHHHHCCCCHHEEEECCCCHHHHHHHH
AGMLGGVALWGYLGVNDKPSQWPAHAHFASPTELHQALVDALA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SLAQIQGVLFDLDGTLADTAPDLVQALNLSLQDVGIAAQPLAAMRYAASHGSFALVDAA
CHHHHHHEEEECCCCCCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCEEEEECC
IPNAADDLRTQVQQGLLAHYQRINGDHCALFTGIAALLDWLELTQLPFGVITNKPARFTR
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHH
PLLRKLNLHLRMPVIISGDSTKHPKPHTAPMLLGAQQLNCAPEHILYLGDAERDLLAAKA
HHHHHCCCEEECCEEEECCCCCCCCCCCCHHHHCHHHHCCCCHHEEEECCCCHHHHHHHH
AGMLGGVALWGYLGVNDKPSQWPAHAHFASPTELHQALVDALA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA