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The map label for this gene is pcoS [H]

Identifier: 160873755

GI number: 160873755

Start: 757279

End: 758715

Strand: Direct

Name: pcoS [H]

Synonym: Sbal195_0633

Alternate gene names: 160873755

Gene position: 757279-758715 (Clockwise)

Preceding gene: 160873754

Following gene: 160873756

Centisome position: 14.16

GC content: 42.66

Gene sequence:

>1437_bases
ATGTATTTTCGAACTCGTATTTTTGCCATATCTATTTTAACCGTGACAGCTGTGCTTACGTTGGTTATTAGCTTAAGTTG
GTCGCGTATTATGACCGTAGAATTGACTAACCTTGATTCTCGCCTTTGTATGGAAGCAAAACGCTTAATACCCAAACGTA
CATTGCTTGATGTAAATAACTCCGCTGACAATATAAGTAATTTACGCGATACTTCGCTTTCTGGTAGCCGGTTAATGACT
GATTTAACGGACAAGTTGCGAGTTAGTTCACCTAACCAATTAATGATCTCAGTAGGCTCTGTGGAGCAAGGGTTCATAAC
CGCGCCAACGGGGGGAGACGTACAAGATGTTATAAGTCGCTTACATTGGGTGAGCGCTGAGCCACTAGCGTTAACCGATA
ACAATAAAGCCAACGCTGTTTGTCAATTTGCCTTTTTTGAACATCAGCAAAACCAATGGCGAGCCAGTTTATTTCAAGCA
TCAAACCAACAAAGCTTTATCGCTGTGGATGTTGCTGCTACCACTAGCCAGTTAACGAGCACCTTGCAGGCAGCGCTGAT
TGTGGTTATTCCTTTTTCTCTACTGCTCAGTATTCTAGGGGCATGGTTTATCGCGACCAATACGATTAGACCAATAAATA
GATTACATAAAGCAATGGATAAGGTGACCCAAAAAGATCTTAGTCACCGTTTACCTGAGCATAAAGAAGACAAAGAGTTC
AAAATGTTGATTGATGCATACAATACGATGCTCGATCGCTTAGAGGACAGTTTTCGACAAGTTTCTCGTTTTACTGCGGA
TGCAGCTCATGAGCTAAAAACACCACTCACAGTGCTAAGAGGCAAGCTTGAACAAGCTGTATTGTCTGAAAACCCATCGC
AATTAGATCTCAATGCCATTCTTGATGAAGTGGGGCATTTGTCAGCCATGACCCGTAAATTGTTGCTGCTATCACAGGCG
GATTCTGGCTCTATGGCGTTGCATTTTGAGCCGATAAACATTACTGAATTAGTCGATGAGTTGATTGCCGATATGACCTT
GTTGTCGGATGAACTGGAGCTTGATTGTGAGATTGAGAAAGATTTAATCACTAAAGGCGATATTGTGTTGTTGAAGCAGC
TGTTAAATAATCTGCTCGTAAACGTAATGCGTTATAGCCTTACTCACAAAGTTGTGACTATTCACACCCGCCAAAACGAG
TCTGTTATAGAGGTGGTGATTAGCAATTTTTGCCTTCCGATATTAAACGACGTTAGGGTCAAACTGTTTAATCGTTTTTA
CCGCGGAGAACCCGCTTATACCCAAGGGATATCCGGCAGTGGTTTAGGGTTAAGTTTAGCCAGAGAAATTGCTCGCGCAC
ACGGTGGCGATCTTTCACTTGAGCCCAGCGAGAGTGAGGTTGTGACTATGCGGCTGTTGTTACCCATCGTTAAATGA

Upstream 100 bases:

>100_bases
CAGTAAAATGGCTTCATTAGAGAAGGCCGGAAAAATGGTCGGCGCCATTGAGTCGATCCGCGGCACAGGTTATCGCCTGA
GCATTCGATAAGGTTTTAAT

Downstream 100 bases:

>100_bases
CAACATTGTCATCCATCAGCGAAGCCTAATCGATACAATTAAGTTAACTCATTAATCGTTAACTTAATTGCTATGGAGGT
TAGGCCATGAAAACCCACAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MYFRTRIFAISILTVTAVLTLVISLSWSRIMTVELTNLDSRLCMEAKRLIPKRTLLDVNNSADNISNLRDTSLSGSRLMT
DLTDKLRVSSPNQLMISVGSVEQGFITAPTGGDVQDVISRLHWVSAEPLALTDNNKANAVCQFAFFEHQQNQWRASLFQA
SNQQSFIAVDVAATTSQLTSTLQAALIVVIPFSLLLSILGAWFIATNTIRPINRLHKAMDKVTQKDLSHRLPEHKEDKEF
KMLIDAYNTMLDRLEDSFRQVSRFTADAAHELKTPLTVLRGKLEQAVLSENPSQLDLNAILDEVGHLSAMTRKLLLLSQA
DSGSMALHFEPINITELVDELIADMTLLSDELELDCEIEKDLITKGDIVLLKQLLNNLLVNVMRYSLTHKVVTIHTRQNE
SVIEVVISNFCLPILNDVRVKLFNRFYRGEPAYTQGISGSGLGLSLAREIARAHGGDLSLEPSESEVVTMRLLLPIVK

Sequences:

>Translated_478_residues
MYFRTRIFAISILTVTAVLTLVISLSWSRIMTVELTNLDSRLCMEAKRLIPKRTLLDVNNSADNISNLRDTSLSGSRLMT
DLTDKLRVSSPNQLMISVGSVEQGFITAPTGGDVQDVISRLHWVSAEPLALTDNNKANAVCQFAFFEHQQNQWRASLFQA
SNQQSFIAVDVAATTSQLTSTLQAALIVVIPFSLLLSILGAWFIATNTIRPINRLHKAMDKVTQKDLSHRLPEHKEDKEF
KMLIDAYNTMLDRLEDSFRQVSRFTADAAHELKTPLTVLRGKLEQAVLSENPSQLDLNAILDEVGHLSAMTRKLLLLSQA
DSGSMALHFEPINITELVDELIADMTLLSDELELDCEIEKDLITKGDIVLLKQLLNNLLVNVMRYSLTHKVVTIHTRQNE
SVIEVVISNFCLPILNDVRVKLFNRFYRGEPAYTQGISGSGLGLSLAREIARAHGGDLSLEPSESEVVTMRLLLPIVK
>Mature_478_residues
MYFRTRIFAISILTVTAVLTLVISLSWSRIMTVELTNLDSRLCMEAKRLIPKRTLLDVNNSADNISNLRDTSLSGSRLMT
DLTDKLRVSSPNQLMISVGSVEQGFITAPTGGDVQDVISRLHWVSAEPLALTDNNKANAVCQFAFFEHQQNQWRASLFQA
SNQQSFIAVDVAATTSQLTSTLQAALIVVIPFSLLLSILGAWFIATNTIRPINRLHKAMDKVTQKDLSHRLPEHKEDKEF
KMLIDAYNTMLDRLEDSFRQVSRFTADAAHELKTPLTVLRGKLEQAVLSENPSQLDLNAILDEVGHLSAMTRKLLLLSQA
DSGSMALHFEPINITELVDELIADMTLLSDELELDCEIEKDLITKGDIVLLKQLLNNLLVNVMRYSLTHKVVTIHTRQNE
SVIEVVISNFCLPILNDVRVKLFNRFYRGEPAYTQGISGSGLGLSLAREIARAHGGDLSLEPSESEVVTMRLLLPIVK

Specific function: Probable member of a two-component regulatory system pcoS/pcoR. May activate pcoR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=255, Percent_Identity=30.1960784313725, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=30.03663003663, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788279, Length=277, Percent_Identity=30.3249097472924, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790551, Length=284, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=27.7533039647577, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787894, Length=292, Percent_Identity=26.027397260274, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=330, Percent_Identity=26.0606060606061, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=24.0343347639485, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=25.3218884120172, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=285, Percent_Identity=27.0175438596491, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=218, Percent_Identity=27.9816513761468, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788549, Length=217, Percent_Identity=27.1889400921659, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=25.9911894273128, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53348; Mature: 53348

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFRTRIFAISILTVTAVLTLVISLSWSRIMTVELTNLDSRLCMEAKRLIPKRTLLDVNN
CCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCHHEEECCC
SADNISNLRDTSLSGSRLMTDLTDKLRVSSPNQLMISVGSVEQGFITAPTGGDVQDVISR
CCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCHHHHHHH
LHWVSAEPLALTDNNKANAVCQFAFFEHQQNQWRASLFQASNQQSFIAVDVAATTSQLTS
HHCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
TLQAALIVVIPFSLLLSILGAWFIATNTIRPINRLHKAMDKVTQKDLSHRLPEHKEDKEF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
KMLIDAYNTMLDRLEDSFRQVSRFTADAAHELKTPLTVLRGKLEQAVLSENPSQLDLNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHH
LDEVGHLSAMTRKLLLLSQADSGSMALHFEPINITELVDELIADMTLLSDELELDCEIEK
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEECH
DLITKGDIVLLKQLLNNLLVNVMRYSLTHKVVTIHTRQNESVIEVVISNFCLPILNDVRV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KLFNRFYRGEPAYTQGISGSGLGLSLAREIARAHGGDLSLEPSESEVVTMRLLLPIVK
HHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYFRTRIFAISILTVTAVLTLVISLSWSRIMTVELTNLDSRLCMEAKRLIPKRTLLDVNN
CCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCHHEEECCC
SADNISNLRDTSLSGSRLMTDLTDKLRVSSPNQLMISVGSVEQGFITAPTGGDVQDVISR
CCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCHHHHHHH
LHWVSAEPLALTDNNKANAVCQFAFFEHQQNQWRASLFQASNQQSFIAVDVAATTSQLTS
HHCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
TLQAALIVVIPFSLLLSILGAWFIATNTIRPINRLHKAMDKVTQKDLSHRLPEHKEDKEF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
KMLIDAYNTMLDRLEDSFRQVSRFTADAAHELKTPLTVLRGKLEQAVLSENPSQLDLNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHH
LDEVGHLSAMTRKLLLLSQADSGSMALHFEPINITELVDELIADMTLLSDELELDCEIEK
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEECH
DLITKGDIVLLKQLLNNLLVNVMRYSLTHKVVTIHTRQNESVIEVVISNFCLPILNDVRV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KLFNRFYRGEPAYTQGISGSGLGLSLAREIARAHGGDLSLEPSESEVVTMRLLLPIVK
HHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]