Click here to switch to the map view.

The map label for this gene is copR [H]

Identifier: 160873754

GI number: 160873754

Start: 756586

End: 757269

Strand: Direct

Name: copR [H]

Synonym: Sbal195_0632

Alternate gene names: 160873754

Gene position: 756586-757269 (Clockwise)

Preceding gene: 160873752

Following gene: 160873755

Centisome position: 14.15

GC content: 45.32

Gene sequence:

>684_bases
ATGAACGTATTGCTTGTCGAAGATGAACAAAAAATTGCAGATTTTATCTGTGAAGGTTTGCGTGCCAAACATTTCAACGT
CACTCATTGTGCCGATGGCAATCAAGGTTATCAGGCGGCAAGTAATAATACTCATGATGTGATTATTCTCGACATTATGC
TACCGGGCAGAGATGGTTTGGATATTCTTCGTTCGCTGCGTCAACAAGGTGTCGATACGCCCATTATTCTGCTTACGGCA
CGTAATGAATTGGGTGATCGCGTTCAAGGGTTAGACATGGGCGCTGATGATTACTTAGCAAAACCGTTTTATGTTGAAGA
GTTGCATGCTCGGATTCAAGCCTTGCTTCGACGGCATGGCGGCACACAACAGCATGTCGTTGAGGTAGGCGCGTTGCAAC
TTGATTGTATTAATCGAAGCATTAATTGTCAGGGTCAATCAGTCGAACTCACTAGCCGAGAATTTAGCTTGCTTGAACAC
TTAATGCGTTCACCTAACCAAGTATTAACCCGGGGGCAGTTGTTGGAGCATGTTTGGGGATACGACTTTGATCCTTGTAC
CAATGTTGTTGATGTGTGCATTAAACGCATCCGCAGTAAAATGGCTTCATTAGAGAAGGCCGGAAAAATGGTCGGCGCCA
TTGAGTCGATCCGCGGCACAGGTTATCGCCTGAGCATTCGATAA

Upstream 100 bases:

>100_bases
TGACAAGTCTTAATTTCTTAAATGACAATGTTGTCATATAGGTTGTGGGTACGGTGCGTCAGGTGAGATACTTTTAAGTG
TTTCCCAAGGATAAAACTCA

Downstream 100 bases:

>100_bases
GGTTTTAATATGTATTTTCGAACTCGTATTTTTGCCATATCTATTTTAACCGTGACAGCTGTGCTTACGTTGGTTATTAG
CTTAAGTTGGTCGCGTATTA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNVLLVEDEQKIADFICEGLRAKHFNVTHCADGNQGYQAASNNTHDVIILDIMLPGRDGLDILRSLRQQGVDTPIILLTA
RNELGDRVQGLDMGADDYLAKPFYVEELHARIQALLRRHGGTQQHVVEVGALQLDCINRSINCQGQSVELTSREFSLLEH
LMRSPNQVLTRGQLLEHVWGYDFDPCTNVVDVCIKRIRSKMASLEKAGKMVGAIESIRGTGYRLSIR

Sequences:

>Translated_227_residues
MNVLLVEDEQKIADFICEGLRAKHFNVTHCADGNQGYQAASNNTHDVIILDIMLPGRDGLDILRSLRQQGVDTPIILLTA
RNELGDRVQGLDMGADDYLAKPFYVEELHARIQALLRRHGGTQQHVVEVGALQLDCINRSINCQGQSVELTSREFSLLEH
LMRSPNQVLTRGQLLEHVWGYDFDPCTNVVDVCIKRIRSKMASLEKAGKMVGAIESIRGTGYRLSIR
>Mature_227_residues
MNVLLVEDEQKIADFICEGLRAKHFNVTHCADGNQGYQAASNNTHDVIILDIMLPGRDGLDILRSLRQQGVDTPIILLTA
RNELGDRVQGLDMGADDYLAKPFYVEELHARIQALLRRHGGTQQHVVEVGALQLDCINRSINCQGQSVELTSREFSLLEH
LMRSPNQVLTRGQLLEHVWGYDFDPCTNVVDVCIKRIRSKMASLEKAGKMVGAIESIRGTGYRLSIR

Specific function: Member of the two-component regulatory system CopS/CopR. Involved in the activation of copper resistance gene operon CopABCD. Phosphorylation of CopR by CopS would convert it into an active state to induce expression of the cop operon by binding to a spec

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=40.9691629955947, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=40.1785714285714, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=39.2857142857143, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=38.2608695652174, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.2678571428571, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=37.3333333333333, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.5638766519824, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=36.4444444444444, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=30.8370044052863, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.2445414847162, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.7586206896552, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=30.0429184549356, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1787229, Length=210, Percent_Identity=30.4761904761905, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=33.6206896551724, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=172, Percent_Identity=28.4883720930233, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25407; Mature: 25407

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLLVEDEQKIADFICEGLRAKHFNVTHCADGNQGYQAASNNTHDVIILDIMLPGRDGL
CCEEEECCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCH
DILRSLRQQGVDTPIILLTARNELGDRVQGLDMGADDYLAKPFYVEELHARIQALLRRHG
HHHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
GTQQHVVEVGALQLDCINRSINCQGQSVELTSREFSLLEHLMRSPNQVLTRGQLLEHVWG
CCHHHHHHHHHEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
YDFDPCTNVVDVCIKRIRSKMASLEKAGKMVGAIESIRGTGYRLSIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MNVLLVEDEQKIADFICEGLRAKHFNVTHCADGNQGYQAASNNTHDVIILDIMLPGRDGL
CCEEEECCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCH
DILRSLRQQGVDTPIILLTARNELGDRVQGLDMGADDYLAKPFYVEELHARIQALLRRHG
HHHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
GTQQHVVEVGALQLDCINRSINCQGQSVELTSREFSLLEHLMRSPNQVLTRGQLLEHVWG
CCHHHHHHHHHEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
YDFDPCTNVVDVCIKRIRSKMASLEKAGKMVGAIESIRGTGYRLSIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449873; 8078459 [H]