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The map label for this gene is 160873509

Identifier: 160873509

GI number: 160873509

Start: 436832

End: 438820

Strand: Reverse

Name: 160873509

Synonym: Sbal195_0384

Alternate gene names: NA

Gene position: 438820-436832 (Counterclockwise)

Preceding gene: 160873510

Following gene: 160873508

Centisome position: 8.21

GC content: 43.49

Gene sequence:

>1989_bases
ATGAAACTCTTCCGATTAGCGACTTTAGCTACGCTTTGCTTGCCTATGCTGTCCCTACATACTTTTGCAGCCGATACCAC
TGCAAGCAATACCTTATTGCTTGCACAGCAGTTCAGTAAAGGTGATGAATATTCAAATGTTAAAATATCTCCTACTGGTA
AATACTTAAGTGCAATCACGAGTGTCGAGGGGAAAAATGTTCTCTTAGTCTTAGATGCTCAAACCAAAAAACTCCTTAAT
GCGATACGCTTTCCCAGTAACGCTCAAGTCGGCGACTATGAATGGGCCAATAATGAGCGACTGGTACTGGCGAAAGAATA
CCTAAAAGGCTGGAGAGATGTTCCGCAGTACTACGGAGAATTATTGGCCGTGAATGCCGATGGTTCACGAAAGGCTTATC
TATTTGGCTTCGAAAGTGGCGAACAACAAACAGGTTCAAATATTAAGAAAAATACTGCAATAAATGCCACAGCATTTATT
CTCGATCCTCTGCCAGATGATGAGCGCTATATGCTGGTCAACGCTATTCCATGGAATAACGAGAGCAGCCTGAATATTGA
ATTAAAACAAGATGTATATCGAGTCGACCTGTTTACTGGGGTTCGTAAACGCATAACAGGAGCCCCGATAGGTCAAGCAC
GTTTTATGACAGATCATGAGGGTGAAGTCCGCTTCGTTGCAGGTGAGGACAGTAAAAACATCACTAAAGTGTTCTACCGC
AAAGACGGTGACTGGATAAATACCGACAAGCTAAACCTAGGCCTAACCGACTTTCAGCCACTTTCCTTCGCCGATGATAA
AAATGCGATTTATGCCGCTGGTCGCTCTCAAGGCGAAACCTTAGGGGTTTACAAGATTAATCTAGAAACGGGCGATAAGA
GCGAGATTATTCAAGATAAAAACGTTGATCCCAGCAATTTTTGGATTAACGGCACCAATAAACAACTTTACGCCGTCGAG
TTTGAAAATGGCTACCCAAGTTATGCCTTCGTCGATAATGAAGATTCGCACGCTAAATTACTAAAAGATCTGCTTGGTGC
CCTCCCAGGCCATCAAGTCCGAATTGTTAGCGAAACCCGAGATGCTGAAAAACTCGTTGTAGTTGCATTTAACGATCGTA
ATCCTGGTGATTACTACATATTTGATACGAAAAAACTGAAACTTGAATATCTAGCAGCCGCTAAAAAATGGCTCGACCCA
GAGCAAATGGCGGAGGTAAAACCCATCAGTTTCACCAGTCGTGATGGTAAAACAATCAACGGTTATTTAACGCTACCTTT
CGGTAAAGAAGCTAAAAATCTGCCCTTAGTTGTCAATCCGCACGGTGGTCCACACGGTATCCGTGACTGGTGGGGCTTTG
ACCCGCAAAACCAATATCTAGCGAGCCAAGGCATAGCAGTTCTACAAGTCAACTTCCGTGGTTCTGGCGGGTATGGCGAT
CAATTTGAACGTGCAGGTTATCAAAAATGGGGCTCAGATATACAACACGATATCATCGACGGTACCCAATATGTCATTGA
CCAAGGTTTCGCCGATAAGGAGCGTATCTGTATCGTTGGCGGCAGTTTTGGTGGTTACAGCGCCTTGCAGAGCGCCGTAC
TTGCTCCAGATATGTTTAAATGCGCCATAGGTGTAGCTGGCGTATATGATCTTGAATTGATGTTTAATGAAGGCGATGTT
GCCAGTAGACGCTCAGGCACTAGCTACCTCAAAGAAGTTCTTGGCCAAGATAAAGCGGTACTCAAAGCAATGTCTCCTTC
TGAAAATGTCGATAAACTCAAAGCAAACATACTATTGGTGCATGGTGGTGAAGATGATCGAGCGCCAATTGAGCAACTCG
AATCCCTCGAAAAAGGCCTAAAAGCTCACAATTATCCTTACCAAAAACTGGTAATGGACAATGAAGGGCACGGTTTTTAT
AACGATGAGCATAGAGCGAAATACTATGAACAAATGCTCAGCTTCCTAAAAACTAATCTAAAACTTTAG

Upstream 100 bases:

>100_bases
TTATTTTTAACCTTCCCTTCTTGTCTCACTAGCACTTTTGTTTTATCCTCGAAAAAACATTTTCAGAACAAAAAACACAA
TAAATTTACAAGGATGTCAG

Downstream 100 bases:

>100_bases
GATTGACTCAAACTTGCCGTCACTGCCAGTCTAAACTCGATTGGCAGTGGCTGATTTAAAGCCGATATCCGATAAGGACT
ATCGGCTTTTTCATGTGGCC

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: AARE; Acyl-peptide hydrolase; APH; Acylaminoacyl-peptidase [H]

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MKLFRLATLATLCLPMLSLHTFAADTTASNTLLLAQQFSKGDEYSNVKISPTGKYLSAITSVEGKNVLLVLDAQTKKLLN
AIRFPSNAQVGDYEWANNERLVLAKEYLKGWRDVPQYYGELLAVNADGSRKAYLFGFESGEQQTGSNIKKNTAINATAFI
LDPLPDDERYMLVNAIPWNNESSLNIELKQDVYRVDLFTGVRKRITGAPIGQARFMTDHEGEVRFVAGEDSKNITKVFYR
KDGDWINTDKLNLGLTDFQPLSFADDKNAIYAAGRSQGETLGVYKINLETGDKSEIIQDKNVDPSNFWINGTNKQLYAVE
FENGYPSYAFVDNEDSHAKLLKDLLGALPGHQVRIVSETRDAEKLVVVAFNDRNPGDYYIFDTKKLKLEYLAAAKKWLDP
EQMAEVKPISFTSRDGKTINGYLTLPFGKEAKNLPLVVNPHGGPHGIRDWWGFDPQNQYLASQGIAVLQVNFRGSGGYGD
QFERAGYQKWGSDIQHDIIDGTQYVIDQGFADKERICIVGGSFGGYSALQSAVLAPDMFKCAIGVAGVYDLELMFNEGDV
ASRRSGTSYLKEVLGQDKAVLKAMSPSENVDKLKANILLVHGGEDDRAPIEQLESLEKGLKAHNYPYQKLVMDNEGHGFY
NDEHRAKYYEQMLSFLKTNLKL

Sequences:

>Translated_662_residues
MKLFRLATLATLCLPMLSLHTFAADTTASNTLLLAQQFSKGDEYSNVKISPTGKYLSAITSVEGKNVLLVLDAQTKKLLN
AIRFPSNAQVGDYEWANNERLVLAKEYLKGWRDVPQYYGELLAVNADGSRKAYLFGFESGEQQTGSNIKKNTAINATAFI
LDPLPDDERYMLVNAIPWNNESSLNIELKQDVYRVDLFTGVRKRITGAPIGQARFMTDHEGEVRFVAGEDSKNITKVFYR
KDGDWINTDKLNLGLTDFQPLSFADDKNAIYAAGRSQGETLGVYKINLETGDKSEIIQDKNVDPSNFWINGTNKQLYAVE
FENGYPSYAFVDNEDSHAKLLKDLLGALPGHQVRIVSETRDAEKLVVVAFNDRNPGDYYIFDTKKLKLEYLAAAKKWLDP
EQMAEVKPISFTSRDGKTINGYLTLPFGKEAKNLPLVVNPHGGPHGIRDWWGFDPQNQYLASQGIAVLQVNFRGSGGYGD
QFERAGYQKWGSDIQHDIIDGTQYVIDQGFADKERICIVGGSFGGYSALQSAVLAPDMFKCAIGVAGVYDLELMFNEGDV
ASRRSGTSYLKEVLGQDKAVLKAMSPSENVDKLKANILLVHGGEDDRAPIEQLESLEKGLKAHNYPYQKLVMDNEGHGFY
NDEHRAKYYEQMLSFLKTNLKL
>Mature_662_residues
MKLFRLATLATLCLPMLSLHTFAADTTASNTLLLAQQFSKGDEYSNVKISPTGKYLSAITSVEGKNVLLVLDAQTKKLLN
AIRFPSNAQVGDYEWANNERLVLAKEYLKGWRDVPQYYGELLAVNADGSRKAYLFGFESGEQQTGSNIKKNTAINATAFI
LDPLPDDERYMLVNAIPWNNESSLNIELKQDVYRVDLFTGVRKRITGAPIGQARFMTDHEGEVRFVAGEDSKNITKVFYR
KDGDWINTDKLNLGLTDFQPLSFADDKNAIYAAGRSQGETLGVYKINLETGDKSEIIQDKNVDPSNFWINGTNKQLYAVE
FENGYPSYAFVDNEDSHAKLLKDLLGALPGHQVRIVSETRDAEKLVVVAFNDRNPGDYYIFDTKKLKLEYLAAAKKWLDP
EQMAEVKPISFTSRDGKTINGYLTLPFGKEAKNLPLVVNPHGGPHGIRDWWGFDPQNQYLASQGIAVLQVNFRGSGGYGD
QFERAGYQKWGSDIQHDIIDGTQYVIDQGFADKERICIVGGSFGGYSALQSAVLAPDMFKCAIGVAGVYDLELMFNEGDV
ASRRSGTSYLKEVLGQDKAVLKAMSPSENVDKLKANILLVHGGEDDRAPIEQLESLEKGLKAHNYPYQKLVMDNEGHGFY
NDEHRAKYYEQMLSFLKTNLKL

Specific function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus [H]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9C family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=236, Percent_Identity=26.271186440678, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI18765694, Length=246, Percent_Identity=28.8617886178862, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI16933540, Length=241, Percent_Identity=26.9709543568465, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI295842403, Length=307, Percent_Identity=26.0586319218241, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI52426756, Length=307, Percent_Identity=26.0586319218241, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI295849272, Length=307, Percent_Identity=26.3843648208469, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI85787627, Length=307, Percent_Identity=26.0586319218241, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI295842359, Length=307, Percent_Identity=26.0586319218241, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI194394146, Length=205, Percent_Identity=29.7560975609756, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25144540, Length=438, Percent_Identity=26.027397260274, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25144537, Length=669, Percent_Identity=23.3183856502242, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25144543, Length=551, Percent_Identity=24.3194192377495, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17552908, Length=222, Percent_Identity=31.0810810810811, Blast_Score=119, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI25149159, Length=256, Percent_Identity=29.6875, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17550672, Length=218, Percent_Identity=27.0642201834862, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508019, Length=205, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508017, Length=205, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550825, Length=228, Percent_Identity=29.8245614035088, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553511, Length=228, Percent_Identity=29.8245614035088, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45551969, Length=228, Percent_Identity=29.8245614035088, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582257, Length=237, Percent_Identity=27.0042194092827, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17933704, Length=218, Percent_Identity=29.3577981651376, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221331178, Length=218, Percent_Identity=29.3577981651376, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI161083744, Length=218, Percent_Identity=29.3577981651376, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR001375
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.4.19.1 [H]

Molecular weight: Translated: 73930; Mature: 73930

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFRLATLATLCLPMLSLHTFAADTTASNTLLLAQQFSKGDEYSNVKISPTGKYLSAIT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCEEEECCCCHHHHHHH
SVEGKNVLLVLDAQTKKLLNAIRFPSNAQVGDYEWANNERLVLAKEYLKGWRDVPQYYGE
CCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHCCC
LLAVNADGSRKAYLFGFESGEQQTGSNIKKNTAINATAFILDPLPDDERYMLVNAIPWNN
EEEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCC
ESSLNIELKQDVYRVDLFTGVRKRITGAPIGQARFMTDHEGEVRFVAGEDSKNITKVFYR
CCEEEEEECCCEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEE
KDGDWINTDKLNLGLTDFQPLSFADDKNAIYAAGRSQGETLGVYKINLETGDKSEIIQDK
CCCCEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCHHHHHCCC
NVDPSNFWINGTNKQLYAVEFENGYPSYAFVDNEDSHAKLLKDLLGALPGHQVRIVSETR
CCCCCCEEEECCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCC
DAEKLVVVAFNDRNPGDYYIFDTKKLKLEYLAAAKKWLDPEQMAEVKPISFTSRDGKTIN
CCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCEEECCCCCEEE
GYLTLPFGKEAKNLPLVVNPHGGPHGIRDWWGFDPQNQYLASQGIAVLQVNFRGSGGYGD
EEEECCCCCCCCCCCEEECCCCCCCCCCHHCCCCCCCHHHHHCCEEEEEEEEECCCCCCC
QFERAGYQKWGSDIQHDIIDGTQYVIDQGFADKERICIVGGSFGGYSALQSAVLAPDMFK
HHHHHHHHHHCCCHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHH
CAIGVAGVYDLELMFNEGDVASRRSGTSYLKEVLGQDKAVLKAMSPSENVDKLKANILLV
HHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHEECCCCCCCCEEEEEEEEE
HGGEDDRAPIEQLESLEKGLKAHNYPYQKLVMDNEGHGFYNDEHRAKYYEQMLSFLKTNL
ECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
KL
CC
>Mature Secondary Structure
MKLFRLATLATLCLPMLSLHTFAADTTASNTLLLAQQFSKGDEYSNVKISPTGKYLSAIT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCEEEECCCCHHHHHHH
SVEGKNVLLVLDAQTKKLLNAIRFPSNAQVGDYEWANNERLVLAKEYLKGWRDVPQYYGE
CCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHCCC
LLAVNADGSRKAYLFGFESGEQQTGSNIKKNTAINATAFILDPLPDDERYMLVNAIPWNN
EEEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCC
ESSLNIELKQDVYRVDLFTGVRKRITGAPIGQARFMTDHEGEVRFVAGEDSKNITKVFYR
CCEEEEEECCCEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEE
KDGDWINTDKLNLGLTDFQPLSFADDKNAIYAAGRSQGETLGVYKINLETGDKSEIIQDK
CCCCEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCHHHHHCCC
NVDPSNFWINGTNKQLYAVEFENGYPSYAFVDNEDSHAKLLKDLLGALPGHQVRIVSETR
CCCCCCEEEECCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCC
DAEKLVVVAFNDRNPGDYYIFDTKKLKLEYLAAAKKWLDPEQMAEVKPISFTSRDGKTIN
CCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCEEECCCCCEEE
GYLTLPFGKEAKNLPLVVNPHGGPHGIRDWWGFDPQNQYLASQGIAVLQVNFRGSGGYGD
EEEECCCCCCCCCCCEEECCCCCCCCCCHHCCCCCCCHHHHHCCEEEEEEEEECCCCCCC
QFERAGYQKWGSDIQHDIIDGTQYVIDQGFADKERICIVGGSFGGYSALQSAVLAPDMFK
HHHHHHHHHHCCCHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHH
CAIGVAGVYDLELMFNEGDVASRRSGTSYLKEVLGQDKAVLKAMSPSENVDKLKANILLV
HHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHEECCCCCCCCEEEEEEEEE
HGGEDDRAPIEQLESLEKGLKAHNYPYQKLVMDNEGHGFYNDEHRAKYYEQMLSFLKTNL
ECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
KL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966; 12037315 [H]