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The map label for this gene is desR [H]

Identifier: 160873477

GI number: 160873477

Start: 399561

End: 400157

Strand: Reverse

Name: desR [H]

Synonym: Sbal195_0352

Alternate gene names: 160873477

Gene position: 400157-399561 (Counterclockwise)

Preceding gene: 160873478

Following gene: 160873476

Centisome position: 7.48

GC content: 54.1

Gene sequence:

>597_bases
ATGAAGATTTTATTGGCGGAAGACCAAGCCATGGTGCGAGGCGCGCTCGCCGCACTCCTCACGCTTGCGGGAGGCTTTAA
TATCACCCAAGCGAGTGACGGCGACGAGGCCCTAGGCCTACTCAAACAGCAAAGCTTTGATCTCTTGCTAACCGACATCG
AAATGCCTGGCCGCACAGGCCTAGAGCTTGCCGCTTGGTTAAAGGATCAACATAGTCAAACTAAGGTCGTGGTCATCACC
ACTTTCGGCCGCGCGGGCTATATCAAACGCGCGATCGAAGCCGGTGTCGGCGGTTTTCTGCTTAAAGATGCGCCCTCGGA
AACCTTAGTCAACGCGATTCAACAAGTTATGGCGGGTAAACGGGTAATCGATCCTGAACTGGCCATGATGGCAATTGGTG
ACGTCGACCCACTCAACGATAAAGAGCGCCGCGCTCTACGCCTCGCCAGTGAAGGCAAATCAACCGCCGACATCGCCGAA
ACCCTCTTTATCGCCGAAGGCACAGTGCGTAACTACCTCTCCGAAGCCATAGCTAAACTCAATGCCAGCAACAGAATCGA
TGCAGCACGCATCGCCAAACAAAAGGGCTGGCTATAA

Upstream 100 bases:

>100_bases
TACGCGAACGTCTCGACAGCTTAGGCGGCAGCTTGAGCTATAATCTCGAACAGGGATATGCATTTACCGTCAGTTTACCT
TTGCAGGGAGCAACAGATTA

Downstream 100 bases:

>100_bases
ACACGCTCACGGTTAACCACTCTTTCGTTCATATCGACAATTTCTGCGGCCTTAGCCGAAACCTAAGGGCCGCAAACTGA
CGTTAGTTATGCTGGCAAAT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKILLAEDQAMVRGALAALLTLAGGFNITQASDGDEALGLLKQQSFDLLLTDIEMPGRTGLELAAWLKDQHSQTKVVVIT
TFGRAGYIKRAIEAGVGGFLLKDAPSETLVNAIQQVMAGKRVIDPELAMMAIGDVDPLNDKERRALRLASEGKSTADIAE
TLFIAEGTVRNYLSEAIAKLNASNRIDAARIAKQKGWL

Sequences:

>Translated_198_residues
MKILLAEDQAMVRGALAALLTLAGGFNITQASDGDEALGLLKQQSFDLLLTDIEMPGRTGLELAAWLKDQHSQTKVVVIT
TFGRAGYIKRAIEAGVGGFLLKDAPSETLVNAIQQVMAGKRVIDPELAMMAIGDVDPLNDKERRALRLASEGKSTADIAE
TLFIAEGTVRNYLSEAIAKLNASNRIDAARIAKQKGWL
>Mature_198_residues
MKILLAEDQAMVRGALAALLTLAGGFNITQASDGDEALGLLKQQSFDLLLTDIEMPGRTGLELAAWLKDQHSQTKVVVIT
TFGRAGYIKRAIEAGVGGFLLKDAPSETLVNAIQQVMAGKRVIDPELAMMAIGDVDPLNDKERRALRLASEGKSTADIAE
TLFIAEGTVRNYLSEAIAKLNASNRIDAARIAKQKGWL

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=25.6038647342995, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790102, Length=192, Percent_Identity=28.125, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1787473, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=23.5, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788712, Length=201, Percent_Identity=22.3880597014925, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21263; Mature: 21263

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLAEDQAMVRGALAALLTLAGGFNITQASDGDEALGLLKQQSFDLLLTDIEMPGRTG
CEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCC
LELAAWLKDQHSQTKVVVITTFGRAGYIKRAIEAGVGGFLLKDAPSETLVNAIQQVMAGK
HHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCC
RVIDPELAMMAIGDVDPLNDKERRALRLASEGKSTADIAETLFIAEGTVRNYLSEAIAKL
CCCCCHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHC
NASNRIDAARIAKQKGWL
CCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MKILLAEDQAMVRGALAALLTLAGGFNITQASDGDEALGLLKQQSFDLLLTDIEMPGRTG
CEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCC
LELAAWLKDQHSQTKVVVITTFGRAGYIKRAIEAGVGGFLLKDAPSETLVNAIQQVMAGK
HHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCC
RVIDPELAMMAIGDVDPLNDKERRALRLASEGKSTADIAETLFIAEGTVRNYLSEAIAKL
CCCCCHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHC
NASNRIDAARIAKQKGWL
CCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]