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The map label for this gene is recG [H]

Identifier: 160873476

GI number: 160873476

Start: 397301

End: 399391

Strand: Reverse

Name: recG [H]

Synonym: Sbal195_0351

Alternate gene names: 160873476

Gene position: 399391-397301 (Counterclockwise)

Preceding gene: 160873477

Following gene: 160873475

Centisome position: 7.47

GC content: 52.56

Gene sequence:

>2091_bases
TTGAGTGCTAACGACTTGCAGCAATTGGATCTTGTTCCGATCACCGACCTCAAAGGCGTCGCCAAAAAGGTCGCGGAGAA
ACTCGCAAAGCTCGGCATCACAACAGTACAAGACCTGCTGTTTCACTTACCCCTGCGCTACGAAGACAGAACCCAAATCT
ATCCGATTGCCGCCCTTATGCCCGGCAGTTACGGCACCATAGAGGCTGAAATCCAATCGACGCAAATCATCCAAGGCCGC
AAGCGTATGCTGGTCTGCAATGTGCGCGACGATACGGGCAGCTTGAGCCTGCGCTTTTTCAACTTTTCTGTCGCCCAGCG
TAATGCCATGCAAAATGGTTTAATGATCCGCGCCTACGGTGAAGTGCGCCGTGGCGGCCATCAAGCTGAGATAGTGCATC
CAGAATATAAAGTCGTGTATCCCGGTGAAGATGTTCACCTAAGCGATACCCTAACGCCGATTTATCCCACAACTGAGGGC
TTAAAACAGGCGAGTTGGCTCAAGCTGACCGAGCAAGCTTTGGTATTACTGGAAGATGGCGGCTTAACTGAGCTGCTGCC
ACCGCAGTTGCAACCGAATAACATCAGCCTTAAACAAGCGTTGCAAACGCTGCATCGACCTCCTGCGGGGATCTCTCAGT
TCGATTTAGAGTTAGGTCAACACCCAGCCCAGCAGCGACTGGTGCAGGAAGAGTTACTCGCTCATAATCTCAGCATGCTA
CGCCTAAGGCAGCGCAGTAATTTAGATGCAGCGGTGACCATGCAGGCCACGGGGCAATTGCTCAATCCCTTCCTTGCCGC
TTTGCCCTTTAAACCCACGGGCGCCCAGCAAAGAGTGGTGGCCGATATAGGCAAAGATTTAGAAAAACCGCACCCTATGA
TGCGCTTAGTACAAGGGGATGTAGGTTCAGGTAAAACCTTAGTCGCGGCGATGGCTGCGCTGCAAGCGATTGAAAACGGT
TATCAAGTTGCCATGATGGCGCCGACCGAGCTATTGGCCGAGCAACATGCAACTAACTTTGCCGCTTGGTTTGAGCCACT
CGGGCTTAAAGTCGGTTGGCTAGCCGGTAAACTTAAAGGCAAGGCAAGAGCGCAATCCCTTGCGGATATTGAATCCGGCG
CAGCCCAAATGGTGATTGGCACCCATGCCATCTTCCAGCAGCATGTGGTCTTTAATAAACTCGGGTTAATTATCATAGAT
GAGCAGCACAGATTCGGCGTACACCAACGCTTAGGTCTGCGGGAAAAGGGCGTGAGCCAAGGTTTCCATCCGCATCAATT
GATCATGACGGCAACGCCGATCCCGCGCACGCTAGCGATGACAGCCTATGCGGATCTCGACACATCCATTATCGATGAAC
TGCCGCCGGGACGGACACCCGTGACCACAGTGGCGATTGCCGATTCTCGCCGCAACGAAGTGCTTGAACGGGTGCGTAAC
GCCGTCATCACAGATAAACGTCAGGCCTATTGGGTGTGTACTTTGATTGAAGAATCCGAAGTGCTCGAATGCCAAGCCGC
CGAAGACACGGCCGAAGAACTGCGCCTCGCCCTACCCGAGCTCAATATTGGCCTAGTGCATGGCAGGTTGAAGAGCGCTG
AGAAACAACAAATCATGGCCGATTTTAAGGCGGGCATCATTCATCTTCTGGTGGCGACAACAGTGATTGAAGTGGGCGTC
GATGTGCCTAATTCCAGCCTGATGATCATTGAAAACCCTGAACGTTTAGGCTTAGCACAACTACACCAACTACGCGGACG
AGTCGGCCGAGGCGCCATCGCAAGCCATTGTGTGTTACTCTACAAGGCGCCATTGAGCCATACCGCCACCCAAAGACTGA
GTGTACTCAGGCAAAGTAATGACGGTTTCATCATAGCGCAGAAAGATTTAGAAATTCGTGGCCCAGGTGAAGTGCTTGGC
ACTAAGCAAACGGGACTGGCCGAGCTGAAAATTGCCGATCTGGTGCGCGATCAAGCTTTGATCCCGCACATTCAAAAACT
GGCAAATCATGTGATGGCGCAGGCCCCCGAAAAAGTCGATGCGATAATCTTACGTTGGCTCGGGCACAAGCAGCACTATG
TGCAGGCTTAG

Upstream 100 bases:

>100_bases
CCGCAAACTGACGTTAGTTATGCTGGCAAATAAGTCCCTCATTCTGCTTGAGATTGCCTTACGCTTATTCTCTGTTAATA
TATGTATAAATTCACAGTGA

Downstream 100 bases:

>100_bases
GCAGTAAAGGGTAAAGGCCGAGGAGTGACATCTGCCTCGATACTCAAAATAAATTGTTTATGTTCAGCTAAGCGCTATAG
ACAAGCGCATGGAAACTTGC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MSANDLQQLDLVPITDLKGVAKKVAEKLAKLGITTVQDLLFHLPLRYEDRTQIYPIAALMPGSYGTIEAEIQSTQIIQGR
KRMLVCNVRDDTGSLSLRFFNFSVAQRNAMQNGLMIRAYGEVRRGGHQAEIVHPEYKVVYPGEDVHLSDTLTPIYPTTEG
LKQASWLKLTEQALVLLEDGGLTELLPPQLQPNNISLKQALQTLHRPPAGISQFDLELGQHPAQQRLVQEELLAHNLSML
RLRQRSNLDAAVTMQATGQLLNPFLAALPFKPTGAQQRVVADIGKDLEKPHPMMRLVQGDVGSGKTLVAAMAALQAIENG
YQVAMMAPTELLAEQHATNFAAWFEPLGLKVGWLAGKLKGKARAQSLADIESGAAQMVIGTHAIFQQHVVFNKLGLIIID
EQHRFGVHQRLGLREKGVSQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIADSRRNEVLERVRN
AVITDKRQAYWVCTLIEESEVLECQAAEDTAEELRLALPELNIGLVHGRLKSAEKQQIMADFKAGIIHLLVATTVIEVGV
DVPNSSLMIIENPERLGLAQLHQLRGRVGRGAIASHCVLLYKAPLSHTATQRLSVLRQSNDGFIIAQKDLEIRGPGEVLG
TKQTGLAELKIADLVRDQALIPHIQKLANHVMAQAPEKVDAIILRWLGHKQHYVQA

Sequences:

>Translated_696_residues
MSANDLQQLDLVPITDLKGVAKKVAEKLAKLGITTVQDLLFHLPLRYEDRTQIYPIAALMPGSYGTIEAEIQSTQIIQGR
KRMLVCNVRDDTGSLSLRFFNFSVAQRNAMQNGLMIRAYGEVRRGGHQAEIVHPEYKVVYPGEDVHLSDTLTPIYPTTEG
LKQASWLKLTEQALVLLEDGGLTELLPPQLQPNNISLKQALQTLHRPPAGISQFDLELGQHPAQQRLVQEELLAHNLSML
RLRQRSNLDAAVTMQATGQLLNPFLAALPFKPTGAQQRVVADIGKDLEKPHPMMRLVQGDVGSGKTLVAAMAALQAIENG
YQVAMMAPTELLAEQHATNFAAWFEPLGLKVGWLAGKLKGKARAQSLADIESGAAQMVIGTHAIFQQHVVFNKLGLIIID
EQHRFGVHQRLGLREKGVSQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIADSRRNEVLERVRN
AVITDKRQAYWVCTLIEESEVLECQAAEDTAEELRLALPELNIGLVHGRLKSAEKQQIMADFKAGIIHLLVATTVIEVGV
DVPNSSLMIIENPERLGLAQLHQLRGRVGRGAIASHCVLLYKAPLSHTATQRLSVLRQSNDGFIIAQKDLEIRGPGEVLG
TKQTGLAELKIADLVRDQALIPHIQKLANHVMAQAPEKVDAIILRWLGHKQHYVQA
>Mature_695_residues
SANDLQQLDLVPITDLKGVAKKVAEKLAKLGITTVQDLLFHLPLRYEDRTQIYPIAALMPGSYGTIEAEIQSTQIIQGRK
RMLVCNVRDDTGSLSLRFFNFSVAQRNAMQNGLMIRAYGEVRRGGHQAEIVHPEYKVVYPGEDVHLSDTLTPIYPTTEGL
KQASWLKLTEQALVLLEDGGLTELLPPQLQPNNISLKQALQTLHRPPAGISQFDLELGQHPAQQRLVQEELLAHNLSMLR
LRQRSNLDAAVTMQATGQLLNPFLAALPFKPTGAQQRVVADIGKDLEKPHPMMRLVQGDVGSGKTLVAAMAALQAIENGY
QVAMMAPTELLAEQHATNFAAWFEPLGLKVGWLAGKLKGKARAQSLADIESGAAQMVIGTHAIFQQHVVFNKLGLIIIDE
QHRFGVHQRLGLREKGVSQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIADSRRNEVLERVRNA
VITDKRQAYWVCTLIEESEVLECQAAEDTAEELRLALPELNIGLVHGRLKSAEKQQIMADFKAGIIHLLVATTVIEVGVD
VPNSSLMIIENPERLGLAQLHQLRGRVGRGAIASHCVLLYKAPLSHTATQRLSVLRQSNDGFIIAQKDLEIRGPGEVLGT
KQTGLAELKIADLVRDQALIPHIQKLANHVMAQAPEKVDAIILRWLGHKQHYVQA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI31542656, Length=317, Percent_Identity=26.1829652996845, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=66.1337209302326, Blast_Score=910, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=390, Percent_Identity=38.7179487179487, Blast_Score=235, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76664; Mature: 76533

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANDLQQLDLVPITDLKGVAKKVAEKLAKLGITTVQDLLFHLPLRYEDRTQIYPIAALM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEEC
PGSYGTIEAEIQSTQIIQGRKRMLVCNVRDDTGSLSLRFFNFSVAQRNAMQNGLMIRAYG
CCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEHHHHHHHHHCCCEEEEEH
EVRRGGHQAEIVHPEYKVVYPGEDVHLSDTLTPIYPTTEGLKQASWLKLTEQALVLLEDG
HHHCCCCCEEEECCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECC
GLTELLPPQLQPNNISLKQALQTLHRPPAGISQFDLELGQHPAQQRLVQEELLAHNLSML
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RLRQRSNLDAAVTMQATGQLLNPFLAALPFKPTGAQQRVVADIGKDLEKPHPMMRLVQGD
HHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
VGSGKTLVAAMAALQAIENGYQVAMMAPTELLAEQHATNFAAWFEPLGLKVGWLAGKLKG
CCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHHHCCCEEEEHHHHHCC
KARAQSLADIESGAAQMVIGTHAIFQQHVVFNKLGLIIIDEQHRFGVHQRLGLREKGVSQ
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCEEEECCCHHCCHHHHCCCCHHHHCC
GFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIADSRRNEVLERVRN
CCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHH
AVITDKRQAYWVCTLIEESEVLECQAAEDTAEELRLALPELNIGLVHGRLKSAEKQQIMA
HHHCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
DFKAGIIHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGAIASHCVLL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHEEEE
YKAPLSHTATQRLSVLRQSNDGFIIAQKDLEIRGPGEVLGTKQTGLAELKIADLVRDQAL
EECCCCHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
IPHIQKLANHVMAQAPEKVDAIILRWLGHKQHYVQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
SANDLQQLDLVPITDLKGVAKKVAEKLAKLGITTVQDLLFHLPLRYEDRTQIYPIAALM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEEC
PGSYGTIEAEIQSTQIIQGRKRMLVCNVRDDTGSLSLRFFNFSVAQRNAMQNGLMIRAYG
CCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEHHHHHHHHHCCCEEEEEH
EVRRGGHQAEIVHPEYKVVYPGEDVHLSDTLTPIYPTTEGLKQASWLKLTEQALVLLEDG
HHHCCCCCEEEECCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECC
GLTELLPPQLQPNNISLKQALQTLHRPPAGISQFDLELGQHPAQQRLVQEELLAHNLSML
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RLRQRSNLDAAVTMQATGQLLNPFLAALPFKPTGAQQRVVADIGKDLEKPHPMMRLVQGD
HHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
VGSGKTLVAAMAALQAIENGYQVAMMAPTELLAEQHATNFAAWFEPLGLKVGWLAGKLKG
CCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHHHCCCEEEEHHHHHCC
KARAQSLADIESGAAQMVIGTHAIFQQHVVFNKLGLIIIDEQHRFGVHQRLGLREKGVSQ
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCEEEECCCHHCCHHHHCCCCHHHHCC
GFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAIADSRRNEVLERVRN
CCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHH
AVITDKRQAYWVCTLIEESEVLECQAAEDTAEELRLALPELNIGLVHGRLKSAEKQQIMA
HHHCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
DFKAGIIHLLVATTVIEVGVDVPNSSLMIIENPERLGLAQLHQLRGRVGRGAIASHCVLL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHEEEE
YKAPLSHTATQRLSVLRQSNDGFIIAQKDLEIRGPGEVLGTKQTGLAELKIADLVRDQAL
EECCCCHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
IPHIQKLANHVMAQAPEKVDAIILRWLGHKQHYVQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]