Click here to switch to the map view.

The map label for this gene is scoA

Identifier: 16080950

GI number: 16080950

Start: 4001976

End: 4002692

Strand: Reverse

Name: scoA

Synonym: BSU38990

Alternate gene names: 16080950

Gene position: 4002692-4001976 (Counterclockwise)

Preceding gene: 255767822

Following gene: 16080949

Centisome position: 94.95

GC content: 50.63

Gene sequence:

>717_bases
ATGGGAAAAGTGCTGTCATCAAGCAAGGAAGCTGCGAAACTGATTCATGATGGGGATACGCTGATCGCGGGAGGGTTTGG
GCTGTGCGGCATCCCTGAACAGCTCATTTTGTCTATAAGAGATCAGGGAGTAAAGGATTTAACCGTTGTCAGCAATAACT
GCGGAGTCGATGACTGGGGGCTTGGTTTGCTTCTGGCTAACAAGCAAATCAAGAAAATGATCGCTTCCTATGTCGGTGAA
AATAAAATTTTTGAGCGGCAGTTTTTAAGCGGAGAGCTTGAGGTAGAGCTTGTTCCCCAAGGAACGCTCGCTGAGAGAAT
TCGTGCAGGCGGTGCAGGCATACCGGGATTTTATACGGCGACAGGCGTCGGCACCTCCATAGCCGAGGGAAAAGAACATA
AAACATTCGGCGGCCGGACTTATGTGCTGGAGCGAGGCATTACCGGCGATGTGGCGATCGTCAAAGCGTGGAAAGCGGAC
ACCATGGGCAATTTGATTTTTAGGAAAACGGCGAGAAATTTCAATCCCATTGCCGCCATGGCAGGCAAGATCACGATTGC
CGAGGCGGAAGAAATCGTGGAAGCAGGAGAGCTCGATCCAGATCACATCCATACGCCGGGAATTTACGTACAGCATGTCG
TGCTTGGCGCGAGCCAAGAAAAACGGATTGAAAAACGAACAGTTCAGCAAGCATCGGGAAAGGGTGAGGCCAAGTGA

Upstream 100 bases:

>100_bases
TTTTTGCGATCACGCTCATTAAAACGGCTGCCGTATTTGCTGTGATCGCGATTTACAGCCTGACTGGTCTAGTGTAGAAG
AAAACGAAAGGGGCATCAAT

Downstream 100 bases:

>100_bases
AGGAAGCGAGAAAACGAATGGTCAAACGGGCTGTACAAGAAATCAAGGACGGCATGAATGTGAATCTCGGGATTGGAATG
CCGACGCTTGTCGCAAATGA

Product: succinyl CoA:3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MGKVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGVKDLTVVSNNCGVDDWGLGLLLANKQIKKMIASYVGE
NKIFERQFLSGELEVELVPQGTLAERIRAGGAGIPGFYTATGVGTSIAEGKEHKTFGGRTYVLERGITGDVAIVKAWKAD
TMGNLIFRKTARNFNPIAAMAGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGASQEKRIEKRTVQQASGKGEAK

Sequences:

>Translated_238_residues
MGKVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGVKDLTVVSNNCGVDDWGLGLLLANKQIKKMIASYVGE
NKIFERQFLSGELEVELVPQGTLAERIRAGGAGIPGFYTATGVGTSIAEGKEHKTFGGRTYVLERGITGDVAIVKAWKAD
TMGNLIFRKTARNFNPIAAMAGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGASQEKRIEKRTVQQASGKGEAK
>Mature_237_residues
GKVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGVKDLTVVSNNCGVDDWGLGLLLANKQIKKMIASYVGEN
KIFERQFLSGELEVELVPQGTLAERIRAGGAGIPGFYTATGVGTSIAEGKEHKTFGGRTYVLERGITGDVAIVKAWKADT
MGNLIFRKTARNFNPIAAMAGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGASQEKRIEKRTVQQASGKGEAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family

Homologues:

Organism=Homo sapiens, GI4557817, Length=254, Percent_Identity=55.5118110236221, Blast_Score=273, Evalue=8e-74,
Organism=Homo sapiens, GI11545841, Length=244, Percent_Identity=51.6393442622951, Blast_Score=239, Evalue=1e-63,
Organism=Escherichia coli, GI1788551, Length=222, Percent_Identity=45.4954954954955, Blast_Score=213, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=55.1440329218107, Blast_Score=262, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21358325, Length=247, Percent_Identity=50.6072874493927, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24655794, Length=247, Percent_Identity=50.6072874493927, Blast_Score=248, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SCOA_BACSU (P42315)

Other databases:

- EMBL:   D83026
- EMBL:   AL009126
- PIR:   B70079
- RefSeq:   NP_391778.1
- PDB:   3CDK
- PDBsum:   3CDK
- ProteinModelPortal:   P42315
- SMR:   P42315
- EnsemblBacteria:   EBBACT00000001195
- GeneID:   937468
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38990
- NMPDR:   fig|224308.1.peg.3904
- GenoList:   BSU38990
- GeneTree:   EBGT00050000001288
- HOGENOM:   HBG288750
- OMA:   VHRIVLN
- ProtClustDB:   CLSK888132
- BioCyc:   BSUB:BSU38990-MONOMER
- BRENDA:   2.8.3.5
- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163
- PANTHER:   PTHR13707
- SMART:   SM00882
- TIGRFAMs:   TIGR02429

Pfam domain/function: PF01144 CoA_trans

EC number: =2.8.3.5

Molecular weight: Translated: 25399; Mature: 25268

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGVKDLTVVSNNCGVDDWG
CCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCC
LGLLLANKQIKKMIASYVGENKIFERQFLSGELEVELVPQGTLAERIRAGGAGIPGFYTA
CEEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCCEEC
TGVGTSIAEGKEHKTFGGRTYVLERGITGDVAIVKAWKADTMGNLIFRKTARNFNPIAAM
CCCCCHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHH
AGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGASQEKRIEKRTVQQASGKGEAK
HCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKVLSSSKEAAKLIHDGDTLIAGGFGLCGIPEQLILSIRDQGVKDLTVVSNNCGVDDWG
CCCCCCCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCC
LGLLLANKQIKKMIASYVGENKIFERQFLSGELEVELVPQGTLAERIRAGGAGIPGFYTA
CEEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCCEEC
TGVGTSIAEGKEHKTFGGRTYVLERGITGDVAIVKAWKADTMGNLIFRKTARNFNPIAAM
CCCCCHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHH
AGKITIAEAEEIVEAGELDPDHIHTPGIYVQHVVLGASQEKRIEKRTVQQASGKGEAK
HCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377