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The map label for this gene is scoB

Identifier: 16080949

GI number: 16080949

Start: 4001329

End: 4001979

Strand: Reverse

Name: scoB

Synonym: BSU38980

Alternate gene names: 16080949

Gene position: 4001979-4001329 (Counterclockwise)

Preceding gene: 16080950

Following gene: 255767821

Centisome position: 94.93

GC content: 49.16

Gene sequence:

>651_bases
GTGAAGGAAGCGAGAAAACGAATGGTCAAACGGGCTGTACAAGAAATCAAGGACGGCATGAATGTGAATCTCGGGATTGG
AATGCCGACGCTTGTCGCAAATGAGATACCCGATGGCGTTCACGTCATGCTTCAGTCGGAAAACGGCTTGCTCGGAATTG
GCCCCTATCCTCTGGAAGGAACGGAAGACGCGGATTTGATCAATGCGGGAAAGGAAACGATCACTGAAGTGACAGGCGCC
TCTTATTTTGACAGCGCTGAGTCATTCGCGATGATAAGAGGCGGGCATATCGATTTAGCTATTCTCGGCGGAATGGAGGT
TTCGGAGCAGGGGGATTTGGCCAATTGGATGATCCCGGGCAAAATGGTAAAAGGGATGGGCGGCGCCATGGATCTCGTCA
ACGGGGCGAAACGAATCGTTGTCATCATGGAGCACGTCAATAAGCATGGTGAATCAAAGGTGAAAAAAACATGCTCCCTT
CCGCTGACAGGCCAGAAAGTCGTACACAGGCTGATTACGGATTTGGCTGTATTTGATTTTGTGAACGGCCGCATGACACT
GACGGAGCTTCAGGATGGTGTCACAATTGAAGAGGTTTATGAAAAAACAGAAGCTGATTTCGCTGTAAGCCAGTCTGTAC
TCAATTCTTAA

Upstream 100 bases:

>100_bases
CGCCGGGAATTTACGTACAGCATGTCGTGCTTGGCGCGAGCCAAGAAAAACGGATTGAAAAACGAACAGTTCAGCAAGCA
TCGGGAAAGGGTGAGGCCAA

Downstream 100 bases:

>100_bases
TGGGAAGGTGTTTGACATGAGAAAACAAGTCGCTTTGGTGACAGGGGCTGCCGGCGGAATCGGATTCGAAATCGCAAGAG
AATTCGCCCGGGAAGGTGCC

Product: succinyl CoA:3-oxoacid CoA-transferase subunit B

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEGTEDADLINAGKETITEVTGA
SYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWMIPGKMVKGMGGAMDLVNGAKRIVVIMEHVNKHGESKVKKTCSL
PLTGQKVVHRLITDLAVFDFVNGRMTLTELQDGVTIEEVYEKTEADFAVSQSVLNS

Sequences:

>Translated_216_residues
MKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEGTEDADLINAGKETITEVTGA
SYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWMIPGKMVKGMGGAMDLVNGAKRIVVIMEHVNKHGESKVKKTCSL
PLTGQKVVHRLITDLAVFDFVNGRMTLTELQDGVTIEEVYEKTEADFAVSQSVLNS
>Mature_216_residues
MKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEGTEDADLINAGKETITEVTGA
SYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWMIPGKMVKGMGGAMDLVNGAKRIVVIMEHVNKHGESKVKKTCSL
PLTGQKVVHRLITDLAVFDFVNGRMTLTELQDGVTIEEVYEKTEADFAVSQSVLNS

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family

Homologues:

Organism=Homo sapiens, GI4557817, Length=214, Percent_Identity=57.9439252336449, Blast_Score=251, Evalue=2e-67,
Organism=Homo sapiens, GI11545841, Length=214, Percent_Identity=53.2710280373832, Blast_Score=234, Evalue=5e-62,
Organism=Escherichia coli, GI1788552, Length=208, Percent_Identity=53.3653846153846, Blast_Score=247, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17531517, Length=213, Percent_Identity=54.9295774647887, Blast_Score=244, Evalue=3e-65,
Organism=Drosophila melanogaster, GI21358325, Length=211, Percent_Identity=54.9763033175355, Blast_Score=238, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24655794, Length=211, Percent_Identity=54.9763033175355, Blast_Score=237, Evalue=3e-63,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): SCOB_BACSU (P42316)

Other databases:

- EMBL:   D83026
- EMBL:   AL009126
- PIR:   C70079
- RefSeq:   NP_391777.1
- PDB:   3CDK
- PDBsum:   3CDK
- ProteinModelPortal:   P42316
- SMR:   P42316
- EnsemblBacteria:   EBBACT00000003236
- GeneID:   937453
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38980
- NMPDR:   fig|224308.1.peg.3903
- GenoList:   BSU38980
- GeneTree:   EBGT00050000001287
- HOGENOM:   HBG353770
- OMA:   MEVWLQS
- PhylomeDB:   P42316
- ProtClustDB:   CLSK2301489
- BioCyc:   BSUB:BSU38980-MONOMER
- BRENDA:   2.8.3.5
- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164
- PANTHER:   PTHR13707
- SMART:   SM00882
- TIGRFAMs:   TIGR02428

Pfam domain/function: PF01144 CoA_trans

EC number: =2.8.3.5

Molecular weight: Translated: 23331; Mature: 23331

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01274 COA_TRANSF_2

Important sites: ACT_SITE 47-47

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEG
CCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCEEEEEECCCCEEECCCCCCCC
TEDADLINAGKETITEVTGASYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWMIPG
CCCCHHHHCCHHHHHHHCCCHHHCCHHHHHEEECCCEEEEEECCCCCCCCCCCCCCCCCH
KMVKGMGGAMDLVNGAKRIVVIMEHVNKHGESKVKKTCSLPLTGQKVVHRLITDLAVFDF
HHHHCCCHHHHHHCCHHHEEHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VNGRMTLTELQDGVTIEEVYEKTEADFAVSQSVLNS
HCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEG
CCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCEEEEEECCCCEEECCCCCCCC
TEDADLINAGKETITEVTGASYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWMIPG
CCCCHHHHCCHHHHHHHCCCHHHCCHHHHHEEECCCEEEEEECCCCCCCCCCCCCCCCCH
KMVKGMGGAMDLVNGAKRIVVIMEHVNKHGESKVKKTCSLPLTGQKVVHRLITDLAVFDF
HHHHCCCHHHHHHCCHHHEEHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VNGRMTLTELQDGVTIEEVYEKTEADFAVSQSVLNS
HCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377