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The map label for this gene is epr

Identifier: 16080891

GI number: 16080891

Start: 3939869

End: 3941806

Strand: Direct

Name: epr

Synonym: BSU38400

Alternate gene names: 16080891

Gene position: 3939869-3941806 (Clockwise)

Preceding gene: 16080888

Following gene: 16080892

Centisome position: 93.46

GC content: 46.44

Gene sequence:

>1938_bases
ATGAAAAACATGTCTTGCAAACTTGTTGTATCAGTCACTCTGTTTTTCAGTTTTCTCACCATAGGCCCTCTCGCTCATGC
GCAAAACAGCAGCGAGAAAGAGGTTATTGTGGTTTATAAAAACAAGGCCGGAAAGGAAACCATCCTGGACAGTGATGCTG
ATGTTGAACAGCAGTATAAGCATCTTCCCGCGGTAGCGGTCACAGCAGACCAGGAGACAGTAAAAGAATTAAAGCAGGAT
CCTGATATTTTGTATGTAGAAAACAACGTATCATTTACCGCAGCAGACAGCACGGATTTCAAAGTGCTGTCAGACGGCAC
TGACACCTCTGACAACTTTGAGCAATGGAACCTTGAGCCCATTCAGGTGAAACAGGCTTGGAAGGCAGGACTGACAGGAA
AAAATATCAAAATTGCCGTCATTGACAGCGGGATCTCCCCCCACGATGACCTGTCGATTGCCGGCGGGTATTCAGCTGTC
AGTTATACCTCTTCTTACAAAGATGATAACGGCCACGGAACACATGTCGCAGGGATTATCGGAGCCAAGCATAACGGCTA
CGGAATTGACGGCATCGCACCGGAAGCACAAATATACGCGGTTAAAGCGCTTGATCAGAACGGCTCGGGGGATCTTCAAA
GTCTTCTCCAAGGAATTGACTGGTCGATCGCAAACAGGATGGACATCGTCAATATGAGCCTTGGCACGACGTCAGACAGC
AAAATCCTTCATGACGCCGTGAACAAAGCATATGAACAAGGTGTTCTGCTTGTTGCCGCAAGCGGTAACGACGGAAACGG
CAAGCCAGTGAATTATCCGGCGGCATACAGCAGTGTCGTTGCGGTTTCAGCAACAAACGAAAAGAATCAGCTTGCCTCCT
TTTCAACAACTGGAGATGAAGTTGAATTTTCAGCACCGGGGACAAACATCACAAGCACTTACTTAAACCAGTATTATGCA
ACGGGAAGCGGAACATCCCAAGCGACACCGCACGCCGCTGCCATGTTTGCCTTGTTAAAACAGCGTGATCCTGCCGAGAC
AAACGTCCAGCTTCGCGAGGAAATGCGGAAAAACATCGTTGATCTTGGTACCGCAGGCCGCGATCAGCAATTTGGCTACG
GCTTAATCCAGTATAAAGCACAGGCAACAGATTCAGCGTACGCGGCAGCAGAGCAAGCGGTGAAAAAAGCGGAACAAACA
AAAGCACAAATCGATATCAACAAAGCGCGAGAACTCATCAGCCAGCTGCCGAACTCCGACGCCAAAACTGCCCTGCACAA
AAGACTGGATAAAGTACAGTCATACAGAAATGTAAAAGATGCGAAAGACAAAGTCGCAAAGGCAGAAAAATATAAAACAC
AGCAAACCGTTGACACAGCACAAACTGCCATCAACAAGCTGCCAAACGGAACAGACAAAAAGAACCTTCAAAAACGCTTA
GACCAAGTAAAACGATACATCGCGTCAAAGCAAGCGAAAGACAAAGTTGCGAAAGCGGAAAAAAGCAAAAAGAAAACAGA
TGTGGACAGCGCACAATCAGCAATTGGCAAGCTGCCTGCAAGTTCAGAAAAAACGTCCCTGCAGAAACGCCTTAACAAAG
TGAAGAGCACCAATTTGAAGACGGCACAGCAATCCGTATCTGCGGCTGAAAAGAAATCAACTGATGCAAATGCGGCAAAA
GCACAATCAGCCGTCAATCAGCTTCAAGCAGGCAAGGACAAAACGGCATTGCAAAAACGGTTAGACAAAGTGAAGAAAAA
GGTGGCGGCGGCTGAAGCAAAAAAAGTGGAAACTGCAAAGGCAAAAGTGAAGAAAGCGGAAAAAGACAAAACAAAGAAAT
CAAAGACATCCGCTCAGTCTGCAGTGAATCAATTAAAAGCATCCAATGAAAAAACAAAGCTGCAAAAACGGCTGAACGCC
GTCAAACCGAAAAAGTAA

Upstream 100 bases:

>100_bases
TAAACAACCCTGCCCATGAAAAATTTTTTCCTTCTTACTATTAATCTCTCTTTTTTTCTCCGATATATATATCAAACATC
ATAGAAAAAGGAGATGAATC

Downstream 100 bases:

>100_bases
CCAAAAACCTTTAAGATTTGCATTCCAAGTCTTAAAGGTTTTTTTCATTCTAAGAACACCACACACAACCTTTTTCCCAT
CCATTGTACAGGCTTTTCAT

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MKNMSCKLVVSVTLFFSFLTIGPLAHAQNSSEKEVIVVYKNKAGKETILDSDADVEQQYKHLPAVAVTADQETVKELKQD
PDILYVENNVSFTAADSTDFKVLSDGTDTSDNFEQWNLEPIQVKQAWKAGLTGKNIKIAVIDSGISPHDDLSIAGGYSAV
SYTSSYKDDNGHGTHVAGIIGAKHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQGIDWSIANRMDIVNMSLGTTSDS
KILHDAVNKAYEQGVLLVAASGNDGNGKPVNYPAAYSSVVAVSATNEKNQLASFSTTGDEVEFSAPGTNITSTYLNQYYA
TGSGTSQATPHAAAMFALLKQRDPAETNVQLREEMRKNIVDLGTAGRDQQFGYGLIQYKAQATDSAYAAAEQAVKKAEQT
KAQIDINKARELISQLPNSDAKTALHKRLDKVQSYRNVKDAKDKVAKAEKYKTQQTVDTAQTAINKLPNGTDKKNLQKRL
DQVKRYIASKQAKDKVAKAEKSKKKTDVDSAQSAIGKLPASSEKTSLQKRLNKVKSTNLKTAQQSVSAAEKKSTDANAAK
AQSAVNQLQAGKDKTALQKRLDKVKKKVAAAEAKKVETAKAKVKKAEKDKTKKSKTSAQSAVNQLKASNEKTKLQKRLNA
VKPKK

Sequences:

>Translated_645_residues
MKNMSCKLVVSVTLFFSFLTIGPLAHAQNSSEKEVIVVYKNKAGKETILDSDADVEQQYKHLPAVAVTADQETVKELKQD
PDILYVENNVSFTAADSTDFKVLSDGTDTSDNFEQWNLEPIQVKQAWKAGLTGKNIKIAVIDSGISPHDDLSIAGGYSAV
SYTSSYKDDNGHGTHVAGIIGAKHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQGIDWSIANRMDIVNMSLGTTSDS
KILHDAVNKAYEQGVLLVAASGNDGNGKPVNYPAAYSSVVAVSATNEKNQLASFSTTGDEVEFSAPGTNITSTYLNQYYA
TGSGTSQATPHAAAMFALLKQRDPAETNVQLREEMRKNIVDLGTAGRDQQFGYGLIQYKAQATDSAYAAAEQAVKKAEQT
KAQIDINKARELISQLPNSDAKTALHKRLDKVQSYRNVKDAKDKVAKAEKYKTQQTVDTAQTAINKLPNGTDKKNLQKRL
DQVKRYIASKQAKDKVAKAEKSKKKTDVDSAQSAIGKLPASSEKTSLQKRLNKVKSTNLKTAQQSVSAAEKKSTDANAAK
AQSAVNQLQAGKDKTALQKRLDKVKKKVAAAEAKKVETAKAKVKKAEKDKTKKSKTSAQSAVNQLKASNEKTKLQKRLNA
VKPKK
>Mature_645_residues
MKNMSCKLVVSVTLFFSFLTIGPLAHAQNSSEKEVIVVYKNKAGKETILDSDADVEQQYKHLPAVAVTADQETVKELKQD
PDILYVENNVSFTAADSTDFKVLSDGTDTSDNFEQWNLEPIQVKQAWKAGLTGKNIKIAVIDSGISPHDDLSIAGGYSAV
SYTSSYKDDNGHGTHVAGIIGAKHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQGIDWSIANRMDIVNMSLGTTSDS
KILHDAVNKAYEQGVLLVAASGNDGNGKPVNYPAAYSSVVAVSATNEKNQLASFSTTGDEVEFSAPGTNITSTYLNQYYA
TGSGTSQATPHAAAMFALLKQRDPAETNVQLREEMRKNIVDLGTAGRDQQFGYGLIQYKAQATDSAYAAAEQAVKKAEQT
KAQIDINKARELISQLPNSDAKTALHKRLDKVQSYRNVKDAKDKVAKAEKYKTQQTVDTAQTAINKLPNGTDKKNLQKRL
DQVKRYIASKQAKDKVAKAEKSKKKTDVDSAQSAIGKLPASSEKTSLQKRLNKVKSTNLKTAQQSVSAAEKKSTDANAAK
AQSAVNQLQAGKDKTALQKRLDKVKKKVAAAEAKKVETAKAKVKKAEKDKTKKSKTSAQSAVNQLKASNEKTKLQKRLNA
VKPKK

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family

Homologues:

Organism=Homo sapiens, GI4506775, Length=239, Percent_Identity=28.4518828451883, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4505579, Length=387, Percent_Identity=27.6485788113695, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI20336244, Length=316, Percent_Identity=30.6962025316456, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71987206, Length=269, Percent_Identity=31.2267657992565, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324576, Length=299, Percent_Identity=31.438127090301, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320775, Length=302, Percent_Identity=30.794701986755, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319893, Length=225, Percent_Identity=32.4444444444444, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45550681, Length=183, Percent_Identity=28.9617486338798, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17136192, Length=268, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUBE_BACSU (P16396)

Other databases:

- EMBL:   X53307
- EMBL:   M22407
- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S11504
- RefSeq:   NP_391719.1
- ProteinModelPortal:   P16396
- SMR:   P16396
- MEROPS:   S08.126
- EnsemblBacteria:   EBBACT00000000713
- GeneID:   937332
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38400
- NMPDR:   fig|224308.1.peg.3845
- GenoList:   BSU38400
- GeneTree:   EBGT00050000000194
- HOGENOM:   HBG752219
- OMA:   VIVVYKN
- PhylomeDB:   P16396
- ProtClustDB:   CLSK888109
- BioCyc:   BSUB:BSU38400-MONOMER
- GO:   GO:0006508
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259
- Gene3D:   G3DSA:3.40.50.200
- PANTHER:   PTHR10795
- PRINTS:   PR00723

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8; SSF52743 Pept_S8_S53; SSF54897 Prot_inh_propept

EC number: NA

Molecular weight: Translated: 69696; Mature: 69696

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00136 SUBTILASE_ASP; PS00137 SUBTILASE_HIS; PS00138 SUBTILASE_SER

Important sites: ACT_SITE 142-142 ACT_SITE 172-172 ACT_SITE 326-326

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMSCKLVVSVTLFFSFLTIGPLAHAQNSSEKEVIVVYKNKAGKETILDSDADVEQQYK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHCCCCCCHHHHHH
HLPAVAVTADQETVKELKQDPDILYVENNVSFTAADSTDFKVLSDGTDTSDNFEQWNLEP
HCCEEEEECCHHHHHHHHCCCCEEEEECCEEEEECCCCCCEEEECCCCCCCCCHHCCCCH
IQVKQAWKAGLTGKNIKIAVIDSGISPHDDLSIAGGYSAVSYTSSYKDDNGHGTHVAGII
HHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEECCCCHHHEECCCCCCCCCCCCEEEEEE
GAKHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQGIDWSIANRMDIVNMSLGTTSDS
ECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCHHHHCCEEEEEEECCCCCCH
KILHDAVNKAYEQGVLLVAASGNDGNGKPVNYPAAYSSVVAVSATNEKNQLASFSTTGDE
HHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHCEEEEEECCCHHHHCCCCCCCCC
VEFSAPGTNITSTYLNQYYATGSGTSQATPHAAAMFALLKQRDPAETNVQLREEMRKNIV
EEECCCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
DLGTAGRDQQFGYGLIQYKAQATDSAYAAAEQAVKKAEQTKAQIDINKARELISQLPNSD
HCCCCCCCCCCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCH
AKTALHKRLDKVQSYRNVKDAKDKVAKAEKYKTQQTVDTAQTAINKLPNGTDKKNLQKRL
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DQVKRYIASKQAKDKVAKAEKSKKKTDVDSAQSAIGKLPASSEKTSLQKRLNKVKSTNLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHH
TAQQSVSAAEKKSTDANAAKAQSAVNQLQAGKDKTALQKRLDKVKKKVAAAEAKKVETAK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVKKAEKDKTKKSKTSAQSAVNQLKASNEKTKLQKRLNAVKPKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNMSCKLVVSVTLFFSFLTIGPLAHAQNSSEKEVIVVYKNKAGKETILDSDADVEQQYK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHCCCCCCHHHHHH
HLPAVAVTADQETVKELKQDPDILYVENNVSFTAADSTDFKVLSDGTDTSDNFEQWNLEP
HCCEEEEECCHHHHHHHHCCCCEEEEECCEEEEECCCCCCEEEECCCCCCCCCHHCCCCH
IQVKQAWKAGLTGKNIKIAVIDSGISPHDDLSIAGGYSAVSYTSSYKDDNGHGTHVAGII
HHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEECCCCHHHEECCCCCCCCCCCCEEEEEE
GAKHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQGIDWSIANRMDIVNMSLGTTSDS
ECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCHHHHCCEEEEEEECCCCCCH
KILHDAVNKAYEQGVLLVAASGNDGNGKPVNYPAAYSSVVAVSATNEKNQLASFSTTGDE
HHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHCEEEEEECCCHHHHCCCCCCCCC
VEFSAPGTNITSTYLNQYYATGSGTSQATPHAAAMFALLKQRDPAETNVQLREEMRKNIV
EEECCCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
DLGTAGRDQQFGYGLIQYKAQATDSAYAAAEQAVKKAEQTKAQIDINKARELISQLPNSD
HCCCCCCCCCCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCH
AKTALHKRLDKVQSYRNVKDAKDKVAKAEKYKTQQTVDTAQTAINKLPNGTDKKNLQKRL
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DQVKRYIASKQAKDKVAKAEKSKKKTDVDSAQSAIGKLPASSEKTSLQKRLNKVKSTNLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHH
TAQQSVSAAEKKSTDANAAKAQSAVNQLQAGKDKTALQKRLDKVKKKVAAAEAKKVETAK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVKKAEKDKTKKSKTSAQSAVNQLKASNEKTKLQKRLNAVKPKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2116590; 3142851; 7934828; 9384377