Click here to switch to the map view.

The map label for this gene is gtaB

Identifier: 16080620

GI number: 16080620

Start: 3665629

End: 3666507

Strand: Direct

Name: gtaB

Synonym: BSU35670

Alternate gene names: 16080620

Gene position: 3665629-3666507 (Clockwise)

Preceding gene: 16080618

Following gene: 16080628

Centisome position: 86.95

GC content: 43.0

Gene sequence:

>879_bases
ATGAAAAAAGTACGTAAAGCCATAATTCCAGCAGCAGGCTTAGGAACACGTTTTCTTCCGGCTACGAAAGCAATGCCGAA
AGAAATGCTTCCTATCGTTGATAAACCTACCATTCAATACATAATTGAAGAAGCTGTTGAAGCCGGTATTGAAGATATTA
TTATCGTAACAGGAAAAAGCAAGCGTGCGATTGAGGATCATTTTGATTACTCTCCTGAGCTTGAAAGAAACCTAGAAGAA
AAAGGAAAAACTGAGCTGCTTGAAAAAGTGAAAAAGGCTTCTAACCTGGCTGACATTCACTATATCCGCCAAAAAGAACC
TAAAGGTCTCGGACATGCTGTCTGGTGCGCACGCAACTTTATCGGCGATGAGCCGTTTGCGGTACTGCTTGGTGACGATA
TTGTTCAGGCTGAAACTCCAGGGTTGCGCCAATTAATGGATGAATATGAAAAAACACTTTCTTCTATTATCGGTGTTCAG
CAGGTGCCCGAAGAAGAAACACACCGCTACGGCATTATTGACCCGCTGACAAGTGAAGGCCGCCGTTATCAGGTGAAAAA
CTTCGTTGAAAAACCGCCTAAAGGCACAGCACCTTCTAATCTTGCCATCTTAGGCCGTTACGTATTCACGCCTGAGATCT
TCATGTATTTAGAAGAGCAGCAGGTTGGCGCCGGCGGAGAAATTCAGCTCACAGACGCCATTCAAAAGCTGAATGAAATT
CAAAGAGTGTTTGCTTACGATTTTGAAGGCAAGCGTTATGATGTTGGTGAAAAGCTCGGCTTTATCACAACAACTCTTGA
ATTTGCGATGCAGGATAAAGAGCTTCGCGATCAGCTCGTTCCATTTATGGAAGGTTTACTAAACAAAGAAGAAATCTAA

Upstream 100 bases:

>100_bases
TTATCCGATATCATAAAAATGTGTAAAAACATATTGAAAAGGGTAAATAGAGAATAGTTTAACCATAAATTTTTTCGATC
ATAAGGAAGGTGCCTTTTAA

Downstream 100 bases:

>100_bases
ACAAAAAGGCTATTGGACATTCATCCAATAGCCTTTTTTTATTTCAACATCAAAGTCAATGTATGCTCTTCATTATCAAC
TGCGAAGACCTGATCAACGG

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKSKRAIEDHFDYSPELERNLEE
KGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNFIGDEPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQ
QVPEEETHRYGIIDPLTSEGRRYQVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEI
QRVFAYDFEGKRYDVGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNKEEI

Sequences:

>Translated_292_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKSKRAIEDHFDYSPELERNLEE
KGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNFIGDEPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQ
QVPEEETHRYGIIDPLTSEGRRYQVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEI
QRVFAYDFEGKRYDVGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNKEEI
>Mature_292_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKSKRAIEDHFDYSPELERNLEE
KGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNFIGDEPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQ
QVPEEETHRYGIIDPLTSEGRRYQVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEI
QRVFAYDFEGKRYDVGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNKEEI

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family

Homologues:

Organism=Escherichia coli, GI1787488, Length=291, Percent_Identity=45.0171821305842, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1788355, Length=277, Percent_Identity=42.5992779783394, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1788351, Length=233, Percent_Identity=30.0429184549356, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790224, Length=239, Percent_Identity=28.4518828451883, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): GTAB_BACSU (Q05852)

Other databases:

- EMBL:   L12272
- EMBL:   Z22516
- EMBL:   AL009126
- PIR:   A40650
- RefSeq:   NP_391447.1
- ProteinModelPortal:   Q05852
- SMR:   Q05852
- EnsemblBacteria:   EBBACT00000000783
- GeneID:   936797
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU35670
- NMPDR:   fig|224308.1.peg.3573
- GenoList:   BSU35670
- GeneTree:   EBGT00050000000561
- HOGENOM:   HBG688195
- OMA:   PKGTAPS
- PhylomeDB:   Q05852
- ProtClustDB:   CLSK2518282
- BioCyc:   BSUB:BSU35670-MONOMER
- BioCyc:   MetaCyc:MONOMER-8824
- BRENDA:   2.7.7.9
- InterPro:   IPR005771
- InterPro:   IPR005835
- TIGRFAMs:   TIGR01099

Pfam domain/function: PF00483 NTP_transferase

EC number: =2.7.7.9

Molecular weight: Translated: 33070; Mature: 33070

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKS
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDYSPELERNLEEKGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNF
CHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
IGDEPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQQVPEEETHRYGIIDPLTSEG
CCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCC
RRYQVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEI
CEEHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHEEHHHHCCCCCCEEHHHHHHHHHHH
QRVFAYDFEGKRYDVGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNKEEI
HHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKS
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDYSPELERNLEEKGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNF
CHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
IGDEPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQQVPEEETHRYGIIDPLTSEG
CCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCC
RRYQVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEI
CEEHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHEEHHHHCCCCCCEEHHHHHHHHHHH
QRVFAYDFEGKRYDVGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNKEEI
HHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659