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The map label for this gene is lytR

Identifier: 16080618

GI number: 16080618

Start: 3663281

End: 3664201

Strand: Direct

Name: lytR

Synonym: BSU35650

Alternate gene names: 16080618

Gene position: 3663281-3664201 (Clockwise)

Preceding gene: 16080605

Following gene: 16080620

Centisome position: 86.9

GC content: 41.8

Gene sequence:

>921_bases
ATGAGAAACGAACGCAGAAAAAAGAAAAAAACTTTATTACTGACAATTTTAACGATAATCGGACTTCTTGTACTCGGAAC
TGGCGGCTATGCATACTACTTATGGCATAAAGCAGCTTCAACCGTGGCAAGTATTCATGAAAGCATTGATAAATCTAAAA
AGAGGGATAAAGAGGTCAGTATCAATAAAAAAGATCCTTTTTCCGTCTTAATCATGGGTGTGGATGAACGCGACGGCGAT
AAGGGCCGTGCCGATACGCTCATTTATATGACCGTTAACCCAAAAACGAATACAACCGACATGGTCAGCATTCCGCGTGA
CACGTATACAAAAATTATCGGAAAAGGCACAATGGATAAAATCAACCATTCATACGCTTTCGGCGGCACACAGATGACGG
TAGACACTGTTGAGAACTTCCTCGATGTTCCGGTTGATTATTTTGTGAAAGTGAACATGGAAAGCTTTAGAGACGTTGTT
GATACACTTGGCGGCATTACAGTTAACAGCACATTCGCGTTCAGTTATGACGGTTATTCGTTCGGCAAAGGAGAAATCAC
GCTGAACGGAAAAGAAGCGCTCGCTTATACCCGGATGAGAAAAGAAGATCCGAGAGGCGACTTCGGACGCCAGGACCGCC
AGCGCCAAGTCATCCAAGGTATTATTAATAAAGGCGCTAATATTTCTTCCATCACGAAATTCGGAGATATGTTTAAAGTT
GTTGAAAATAATGTGAAAACGAACTTGACCTTCGATAACATGTGGGATATCCAGTCCGATTACAAAGGTGCGCGGAAACA
TATTAAACAGCACGAACTAAAAGGTACAGGCACGAAAATCAATGGAATTTACTACTACCAAGCTGATGAAAGCGCCCTTT
CCGATATTACAAAAGAGCTGAAGGAAAGCCTCGAAAAGTAA

Upstream 100 bases:

>100_bases
AAAACGACTATTTTAGGATTTCATTCTTGTATTAAATAGAGTTGTATTTATTGGAAATTTAACTCATAATGAAAGTAATT
TAACAGACGAGGTGCAAAGG

Downstream 100 bases:

>100_bases
AACAAAAAGAAGCTTCGCACAATGTGCAAAGCTTCTTTTTTATTTGCCTGTAAATGAATCCGGTTGTTCTTTTCGATACC
CGTAATGAAACAGCAATTCT

Product: membrane-bound transcriptional regulator LytR

Products: NA

Alternate protein names: Membrane-bound protein lytR

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRNERRKKKKTLLLTILTIIGLLVLGTGGYAYYLWHKAASTVASIHESIDKSKKRDKEVSINKKDPFSVLIMGVDERDGD
KGRADTLIYMTVNPKTNTTDMVSIPRDTYTKIIGKGTMDKINHSYAFGGTQMTVDTVENFLDVPVDYFVKVNMESFRDVV
DTLGGITVNSTFAFSYDGYSFGKGEITLNGKEALAYTRMRKEDPRGDFGRQDRQRQVIQGIINKGANISSITKFGDMFKV
VENNVKTNLTFDNMWDIQSDYKGARKHIKQHELKGTGTKINGIYYYQADESALSDITKELKESLEK

Sequences:

>Translated_306_residues
MRNERRKKKKTLLLTILTIIGLLVLGTGGYAYYLWHKAASTVASIHESIDKSKKRDKEVSINKKDPFSVLIMGVDERDGD
KGRADTLIYMTVNPKTNTTDMVSIPRDTYTKIIGKGTMDKINHSYAFGGTQMTVDTVENFLDVPVDYFVKVNMESFRDVV
DTLGGITVNSTFAFSYDGYSFGKGEITLNGKEALAYTRMRKEDPRGDFGRQDRQRQVIQGIINKGANISSITKFGDMFKV
VENNVKTNLTFDNMWDIQSDYKGARKHIKQHELKGTGTKINGIYYYQADESALSDITKELKESLEK
>Mature_306_residues
MRNERRKKKKTLLLTILTIIGLLVLGTGGYAYYLWHKAASTVASIHESIDKSKKRDKEVSINKKDPFSVLIMGVDERDGD
KGRADTLIYMTVNPKTNTTDMVSIPRDTYTKIIGKGTMDKINHSYAFGGTQMTVDTVENFLDVPVDYFVKVNMESFRDVV
DTLGGITVNSTFAFSYDGYSFGKGEITLNGKEALAYTRMRKEDPRGDFGRQDRQRQVIQGIINKGANISSITKFGDMFKV
VENNVKTNLTFDNMWDIQSDYKGARKHIKQHELKGTGTKINGIYYYQADESALSDITKELKESLEK

Specific function: Plays an attenuator role for both its own and lytABC operon expression, and thus regulates the expression of the major autolytic amidase of B.subtilis

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYAT_BACSU (Q02115)

Other databases:

- EMBL:   M87645
- EMBL:   AL009126
- EMBL:   Z22516
- PIR:   A47679
- RefSeq:   NP_391445.1
- ProteinModelPortal:   Q02115
- SMR:   Q02115
- EnsemblBacteria:   EBBACT00000002442
- GeneID:   936787
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU35650
- NMPDR:   fig|224308.1.peg.3571
- GenoList:   BSU35650
- GeneTree:   EBGT00070000031934
- HOGENOM:   HBG304505
- OMA:   TQDQTTT
- ProtClustDB:   PRK09379
- BioCyc:   BSUB:BSU35650-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01140
- InterPro:   IPR004474
- TIGRFAMs:   TIGR00350

Pfam domain/function: PF03816 LytR_cpsA_psr

EC number: NA

Molecular weight: Translated: 34587; Mature: 34587

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12a64a2c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNERRKKKKTLLLTILTIIGLLVLGTGGYAYYLWHKAASTVASIHESIDKSKKRDKEVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
INKKDPFSVLIMGVDERDGDKGRADTLIYMTVNPKTNTTDMVSIPRDTYTKIIGKGTMDK
CCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEECCHHHHHHHHCCCCHHH
INHSYAFGGTQMTVDTVENFLDVPVDYFVKVNMESFRDVVDTLGGITVNSTFAFSYDGYS
CCCCEEECCCEEEHHHHHHHHHCCCHHEEEECHHHHHHHHHHHCCEEECCEEEEEECCEE
FGKGEITLNGKEALAYTRMRKEDPRGDFGRQDRQRQVIQGIINKGANISSITKFGDMFKV
ECCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VENNVKTNLTFDNMWDIQSDYKGARKHIKQHELKGTGTKINGIYYYQADESALSDITKEL
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHHHHHHHHHH
KESLEK
HHHHCH
>Mature Secondary Structure
MRNERRKKKKTLLLTILTIIGLLVLGTGGYAYYLWHKAASTVASIHESIDKSKKRDKEVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
INKKDPFSVLIMGVDERDGDKGRADTLIYMTVNPKTNTTDMVSIPRDTYTKIIGKGTMDK
CCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEECCHHHHHHHHCCCCHHH
INHSYAFGGTQMTVDTVENFLDVPVDYFVKVNMESFRDVVDTLGGITVNSTFAFSYDGYS
CCCCEEECCCEEEHHHHHHHHHCCCHHEEEECHHHHHHHHHHHCCEEECCEEEEEECCEE
FGKGEITLNGKEALAYTRMRKEDPRGDFGRQDRQRQVIQGIINKGANISSITKFGDMFKV
ECCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VENNVKTNLTFDNMWDIQSDYKGARKHIKQHELKGTGTKINGIYYYQADESALSDITKEL
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHHHHHHHHHH
KESLEK
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1357079; 9384377; 8126437